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Antiulcers Drugs

Total questions: 33

Worksheet time: 17mins

Name
Class
Date
1.

Which patient is at highest risk for developing peptic ulcer disease?

a)

25-year-old who exercises daily

b)

45-year-old with lactose intolerance

c)

60-year-old who uses NSAIDs daily

d)

30-year-old who avoids caffeine

2.

Antacids work by:

a)

Blocking histamine receptors

b)

Inhibiting proton pumps

c)

Neutralizing hydrochloric acid

d)

Eradicating H. pylori

3.

Which antacid combines magnesium and aluminum to balance bowel effects?

a)

Tums

b)

Rolaids

c)

Maalox

d)

Sucralfate

4.

Which instruction is most important when administering antacids?

a)

Crush tablets before use

b)

Separate from other oral drugs by at least 1 hour

c)

Take with other oral medications

d)

Take on an empty stomach only

5.

Which medication is an H2 receptor antagonist?

a)

Omeprazole

b)

Sucralfate

c)

Misoprostol

d)

Famotidine

6.

Which side effect is associated with H2 blockers?

a)

Hypomagnesemia

b)

Erectile dysfunction

c)

Tendon rupture

d)

Ototoxicity

7.

Which drugs are classified as proton pump inhibitors?
Select all that apply.

a)

Omeprazole

b)

Pantoprazole

c)

Famotidine

d)

Lansoprazole

8.

Long-term use of PPIs increases the risk of:

a)

Kidney stones

b)

Liver failure

c)

Osteoporosis and hip fractures

d)

Hearing loss

9.

Which lab value should be monitored in a patient on long-term PPI therapy?

a)

Potassium

b)

Sodium

c)

Platelets

d)

Magnesium

10.

PPIs can cause hypomagnesemia and vitamin B12 deficiency

a)

True

b)

False

c)

False, only hypomagnesemia

11.

How should PPIs be administered for best effectiveness?

a)

At bedtime

b)

With meals

c)

Before meals, preferably in the morning

d)

After meals

12.

Sucralfate works by:

a)

Neutralizing stomach acid

b)

Blocking histamine receptors

c)

Coating and protecting the ulcer

d)

Decreasing prostaglandin production

13.

Histamine H2 Receptor Antagonists works by

a)

Blocks histamine; histamine increases acid production

b)

Decreases acid secretion; Inhibits hydrogen/potassium ATPase

c)

Covers ulcer and protects it from acid and pepsin

d)

decreases gastric acid secretion and increases the production of protective mucus

14.

Which is the most common side effect of sucralfate?

a)

Diarrhea

b)

Constipation

c)

Hypotension

d)

Hypoglycemia

15.

When should sucralfate be administered?

a)

With meals

b)

Immediately after meals

c)

Once daily in the morning

d)

On an empty stomach, 1 hour before meals and at bedtime

16.

Proton Pump Inhibitors decreases acid secretion by Inhibiting hydrogen/potassium ATPase

a)

True

b)

False

17.

Which medication is a prostaglandin analogue?

a)

Famotidine

b)

Vancomycin

c)

Sucralfate

d)

Misoprostol

18.

Misoprostol is primarily used to:

a)

Treat GERD

b)

Prevent NSAID-induced ulcers

c)

Neutralize gastric acid

d)

Eradicate H. pylori

19.

Misoprostol is contraindicated in which patient?

a)

Older adults

b)

Patient with GERD

c)

Pregnant woman

d)

Patient taking NSAIDs

20.

Sucralfate belongs to which drug class?

a)

Proton pump inhibitor

b)

Pepsin inhibitor / GI protectant

c)

Antacid

d)

Prostaglandin analogue

21.

Which of the following drugs is an antacid?

a)

Maalox (magnesium hydroxide/aluminum hydroxide)

b)

Famotidine

c)

Sucralfate

d)

Omeprazole

22.

Match the drug with its main purpose or action:

  1. 1. Omeprazole

  2. 2. Sucralfate

  3. 3. Misoprostol

  4. 4. Maalox

A. Neutralizes gastric acid
B. Coats and protects ulcers
C. Suppresses gastric acid and increases mucus for NSAID prevention
D. Inhibits hydrogen/potassium ATPase to reduce acid

(a)  

23.

Which is a common side effect of H2 blockers like Famotidine?

a)

Diarrhea

b)

Headache and dizziness

c)

Tinnitus

d)

Hypomagnesemia

24.

What should the nurse monitor for a patient taking antacids (e.g., Maalox)?

a)

Serum magnesium and phosphate

b)

Platelet count

c)

Hearing loss

d)

Liver function tests

25.

A patient taking PPIs long-term should be monitored for:

a)

Liver toxicity

b)

Photosensitivity

c)

Hypomagnesemia, B12 deficiency, osteoporosis

d)

Hypomagnesemia oly

26.

Which antiulcer medication’s side effect is constipation and requires increased fluids and fiber?

a)

Omeprazole

b)

Sucralfate

c)

Misoprostol

d)

Famotidine

27.

Patient teaching for all antiulcer drugs should include:

a)

Avoid alcohol, aspirin, and NSAIDs

b)

Stop medication once symptoms improve

c)

Take only before bedtime

d)

Crush all tablets for faster action

28.

A patient taking antacids for more than 2 weeks should:

a)

Continue until symptoms resolve

b)

Consult HCP

c)

Take double dose

d)

Stop abruptly

29.

Which medications are most likely to be included in a dual drug therapy program for peptic ulcer disease from H. pylori?

a)

Tetracycline and metronidazole

b)

Omeprazole and clarithromycin

c)

Ranitidine and amoxicillin

d)

Ciprofloxacin and sucralfate

30.

A patient with peptic ulcer disease is noted to have a positive breath test for H. pylori. The nurse would anticipate treating the patient with

a)

antacids and narcotics.

b)

pepsin inhibitors and antiemetics.

c)

proton pump inhibitors and antibiotics.

d)

emetic agents and tranquilizers.

31.

An older adult patient reports taking aluminum hydroxide on a daily basis to relieve symptoms of gastroesophageal reflux disease. The nurse needs to evaluate for which condition?

a)

Constipation

b)

Diarrhea

c)

Flatuenlence

d)

Abdominal Pain

32.

A patient with a gastric ulcer is ordered sucralfate. This medication works to

a)

calm the patient to reduce acid production.

b)

block the H2 receptors

c)

neutralize the gastric acids

d)

coat the gastric lining

33.

A patient who complains of gastric distress from aspirin will most likely benefit from the administration of which medication?

a)

Misoprotsol

b)

Lanzoprazole

c)

Magaldrate

d)

Magnesium Trisilicate

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