Anutonomic Nervous System Drugs

Multiple Choice

Which neurotransmitter is released by postganglionic fibers in the sympathetic nervous system?

• Acetylcholine

• Dopamine

• Norepinephrine

• Serotonin

Multiple Select

Which of the following are effects of sympathetic nervous system activation?

• Dilates pupils

• Increases heart rate

• Stimulates bile release

• Constricts bronchioles

Fill in the Blanks

Drugs that mimic the sympathetic neurotransmitters norepinephrine and epinephrine are called

agonists.

Multiple Choice

Which adrenergic agonist drug is primarily used for bronchodilation in emergency situations such as anaphylaxis?

• Dopamine

• Norepinephrine

• Epinephrine

• Acetylcholine

Open Ended

Explain how adrenergic agonist drugs affect the cardiovascular and respiratory systems.

Multiple Choice

Which of the following are the four main adrenergic receptors?

• Alpha1, Alpha2, Beta1, Beta2

• Alpha, Beta, Gamma, Delta

• Alpha1, Beta1, Gamma1, Delta2

• Alpha2, Beta2, Gamma2, Delta1

Multiple Choice

Which adrenergic receptor is primarily responsible for bronchodilation?

• α1 receptor

• α2 receptor

• β1 receptor

• β2 receptor

Fill in the Blanks

The drug Methyldopa is an agonist for the alpha

-adrenergic receptor.

Multiple Choice

Stimulation of which adrenergic receptor leads to vasodilation and decreased blood pressure?

• α1 receptor

• α2 receptor

• β1 receptor

• β2 receptor

Open Ended

Explain how stimulation of beta-1 adrenergic receptors affects the heart and kidney.

Multiple Select

Which of the following are effects of beta-2 adrenergic receptor activation?

• Bronchodilation

• Increased heart contractility

• Relaxation of uterine smooth muscle

• Activation of glycogenolysis

Multiple Choice

Which enzyme is responsible for inactivating norepinephrine inside the neuron?

• Catechol-O-methyltransferase (COMT)

• Monoamine oxidase (MAO)

• Acetylcholinesterase

• Adenylate cyclase

Multiple Choice

Which of the following best describes the mechanism of action of indirect-acting sympathomimetic drugs?

• They directly bind to adrenergic receptors to produce effects.

• They increase the release or inhibit the reuptake of norepinephrine.

• They act on both adrenergic receptors and increase norepinephrine release.

• They inhibit the degradation of norepinephrine by enzymes.

Multiple Select

Which of the following are ways sympathomimetic drugs can prolong the action of neurotransmitters?

• Inhibiting reuptake

• Inhibiting degradation by enzyme action

• Increasing neurotransmitter synthesis

• Blocking receptor binding

Fill in the Blanks

Examples of endogenous catecholamines are epinephrine, norepinephrine, and

.

Multiple Choice

Which adrenergic receptor subtype is primarily responsible for bronchodilation when stimulated by agonists like albuterol?

• Alpha-1

• Alpha-2

• Beta-1

• Beta-2

Open Ended

Explain the difference between selective and nonselective adrenergic agonists, providing an example of each.

Multiple Choice

What is a primary clinical use of epinephrine due to its nonselective action on adrenergic receptors?

• Treatment of hypertension

• Management of anaphylactic shock

• Relief of chronic pain

• Reduction of fever

Multiple Choice

Which of the following is a common side effect of Albuterol Sulfate?

• Bradycardia

• Hyperglycemia

• Hypotension

• Constipation

Open Ended

Explain how alpha 2-adrenergic agonists lower blood pressure and provide an example of such a drug.

Fill in the Blanks

Drugs that block the effects of the adrenergic neurotransmitter are called

.

Multiple Select

Which of the following are true about alpha-adrenergic antagonists?

• They block alpha-adrenergic receptor sites.

• They are divided into selective and nonselective groups.

• They are used to treat peripheral vascular disease.

• They increase blood pressure.

Multiple Choice

Match the adrenergic blocker receptor to its primary response: Alpha1, Beta1, Beta2.

• Alpha1 - Vasodilation; Beta1 - Decreases heart rate; Beta2 - Constricts bronchioles

• Alpha1 - Increases heart rate; Beta1 - Vasodilation; Beta2 - Inhibits glycogenolysis

• Alpha1 - Constricts bronchioles; Beta1 - Reduces force of contractions; Beta2 - Decreases blood glucose

• Alpha1 - Suppresses ejaculation; Beta1 - Increases heart rate; Beta2 - Contracts uterus

Open Ended

Why are nonselective beta blockers contraindicated in patients with asthma?

Multiple Choice

What are the two main divisions of the peripheral nervous system?

• Autonomic nervous system and somatic nervous system

• Brain and spinal cord

• Sympathetic and parasympathetic nervous systems

• Central and peripheral nervous systems