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Immune System

Total questions: 83

Worksheet time: 49mins

Name
Class
Date
1.
What is the interstitial fluid?
a)
fluid that surrounds lymph nodes
b)
fluid that surrounds body cells
c)
fluid that surrounds lymphocytes
d)
fluid that surrounds monocytes
2.
What are macrophages?
a)
lymph nodes
b)
attack foreign substances
c)
large ducts
d)
swallow phaocytose
3.
What lymphocytes are present in nodes?
a)
t and b
b)
b and m
c)
m and t
d)
t and p
4.
what do lymph nodes produce?
a)
lymphocytes
b)
lympocytes
c)
lymphcytes
d)
lymphocites
5.
where is the thymus gland located?
a)
upper mediastinum between the lungs
b)
upper right quadrant 
c)
lower left quadrant 
d)
upper left quadrant?
6.
what does cell mediated immunity NOT involve 
a)
antibodies
b)
t cells
7.

Vaccinations help prepare the body to fight invasions of a specific pathogen by

a)

inhibiting antigen production

b)

stimulating antibody production

c)

inhibiting WBC production

d)

stimulating RBC production

8.

T cells complete their development in the

a)

bone marrow

b)

spleen

c)

lymph nodes

d)

thymus

9.

Which of the following is an example of naturally acquired active immunity?

a)

antibodies passing from mother to child in the womb

b)

a child receives the MMR vaccine

c)

a child is bitten by a rabid animal and receives injections of antibodies

d)

an adults contracts Strep throat and recovers in a couple of weeks

10.

B lymphocytes are responsible for

a)

humoral immunity

b)

cell-mediated immunity

c)

regulating the immune response

d)

immunological surveillance

11.

This type of immune cell will cause a secondary response if the same antigen is present again.

a)

Basophil

b)

memory cell

c)

natural killer cell

d)

helper T cell

12.

Neutrophils, basophils, eosinophils, monocytes and lymphocytes are all examples of

a)

leukocytes

b)

neurons

c)

passive immunity

d)

cytotoxic t cells

13.

Which cell is needed to activate B cells?

a)

phagocytes

b)

plasma cells

c)

helper T cells

d)

cytotoxic T cells

14.

A Y-shaped protein that attaches to a specific foreign substance is called the

a)

T cell

b)

antigen

c)

antibody

d)

B cell

15.

Which of the following is NOT a sign of inflammation?

a)

redness

b)

swelling

c)

paleness

d)

pain

16.

The most numerous and main cell in the inflammatory response is the ________.

a)

monocyte

b)

neutrophil

c)

macrophage

d)

basophil

17.

This type of immune cell is present in parasitic infections.

a)

basophils

b)

eosinophils

c)

neutrophils

d)

monocytes

18.

This type of immune cells is present during allergic reactions due it's release of histamine.

a)

neutrophil

b)

esosinophil

c)

basophil

d)

monocyte

19.

___________ are glands that like filters to remove germs. They are found in the armpit, groin and neck.

a)

thymus

b)

spleen

c)

lymph nodes

d)

lymph

20.

A(n) _________ reaction occurs when the immune system overreacts to exposure to antigens in the environment.

a)

lymph nodes

b)

infection

c)

allergic

d)

immune

21.

The __________ system protects your body from sickness and germs.

a)

cardiovascular

b)

immune

c)

respiratory

d)

urinary

22.

Cytotoxic T cells

a)

do not require a specific antigen

b)

rid the body of cancer cells

c)

rid the body of cells that have become infected with viruses

d)

both b and c

23.

Which of the following cells are primarily targeted by HIV?

a)

nerve cells

b)

phagocytes

c)

helper T cells

d)

cytotoxic T cells

24.

The first line of defense is

a)

the body's barriers to keeping infection out

b)

the inflammatory response

c)

the infection response

d)

the acquired immune response

25.

These molecules are recognized as foreign to the body.

a)

B-cells

b)

T-cells

c)

antigens

d)

antibodies

26.

Chemical messengers produced by cells of the immune system which bind to the specific receptors on pathogens

a)

B cells

b)

T cells

c)

antigens

d)

antibodies

27.

A(n)________ is when the production or function of immune cells is abnormal.

a)

infectious

b)

pathogen

c)

immunodeficiency

d)

active immunity

28.

Histamines directly cause:

a)

Helper T cells to mark pathogens for destruction

b)

Cytotoxic T cells to become activated

c)

B and T cells to create memory cells

d)

Blood vessels to dilate and leak fluid and WBC's

29.

Saliva, tears, and sweat contain which enzyme?

a)

lysozyme

b)

protein kinase

c)

hydrochloric acid

d)

lactase

30.

Interferon is a chemical messenger sent from a virus infected cell. What is its function?

a)

Causes neighboring cells to make proteins to block viral reproduction

b)

Calls white blood cells over to take care of the infection

c)

Causes neighboring cells to build up thicker cell membranes so the viruses can't enter

31.

Which of the following are considered "Professional Antigen Presenting Cells"?

a)

B Cells

b)

Macrophage

c)

Dendritic Cells

d)

T Cells

32.

Means: "programmed cell death"

a)

Natural Killer Cell

b)

Mitosis

c)

Apoptosis

d)

CD4 and CD8

33.

Natural Killer (NK) Cells target:

a)

Cancerous cells

b)

Virus invaded cells

c)

A specific antigen marker on some type of pathogen

34.

Natural Killer cells cause which of the following?

a)

Release of cytokines which alert other immune cells

b)

Punch holes in a cell infected with viruses

c)

Release an enzyme into an infected cell which switches on apoptosis

d)

Cytotoxic T cells to shoot everything in site with perforin

35.

Helper T Cells have a special protein on their surface called:

a)

CD4

b)

CD8

36.

CD8 proteins are found on which of the following cell types?

a)

B Cells

b)

Macrophages

c)

Cytotoxic T Cells

d)

Natural Killer Cells

37.

A B cell that is actively making antibodies is called a(n)

a)

memory B cell

b)

plasma cell

c)

Helper T cell

d)

Naive B cell

38.

Helper T Cells activate which of the following?

a)

Cytotoxic T Cells

b)

B Cells

c)

Macrophages

d)

Natural Killer Cells

39.

What happens directly after a Helper T cell bumps into an antigen that matches it's surface receptor?

a)

It divides and differentiates like crazy

b)

The cell turns into a memory T cell

c)

It shoots enzymes out to kill the pathogen

d)

It creates antibodies

40.

If a person has already had chicken pox, why do they generally not get sick a second time?

a)

Memory B and T cells activate the immune system before the virus has a chance to make you sick

b)

Natural killer cells recognize the pathogen quicker

c)

Your 1st line of defense does a better job

41.

Which of the following is part of the humoral response?

a)

antibodies

b)

Cytotoxic T cells

c)

Natural Killer Cells

d)

Lysozyme

42.

After an infection is effectively been dealt with, what happens?

a)

Suppressor T cells help stop the immune response

b)

More antibodies are made so that memory cells can keep record

c)

Cytotoxic T cells shed their CD8 proteins

43.

Which of the following is NOT part of the 3rd line of defense?

a)

B cells

b)

T Cells

c)

Antibodies

d)

Macrophages

44.
Where are lymphocytes produced?
a)
bladder
b)
bone marrow
c)
thymus
d)
appendix
45.
Both T cells and B cells produce memory cells.
a)
True
b)
False
46.
Fluid that is pushed out of the capillaries and into the surrounding tissues 
a)
mucus
b)
tears
c)
lymph
d)
saliva
47.
An immune response that does not involve antibodies but rather involves the activation of macrophages and natural killer cells:
a)
Acquired Passive Immunity
b)
Natural Immunity
c)
Acquired Active Immunity
d)
Cell-Mediated Immunity
48.
The nurse practitioner gives out immunization shots for measles, mumps and rubella. What type of immunity to these diseases would someone get?
a)
Artificial acquired immunity
b)
Natural acquired immunity
c)
Natural immunity
d)
Passive acquired immunity
49.
A primary immune response is ____; and a secondary immune response is___.
a)
very important; less important
b)
very rapid; very slow
c)
slower; faster
d)
none of these is correct
50.
Which of the following are embedded in the wall of the small intestines?
a)
thymus
b)
spleen
c)
tonsils
d)
Peyer's patches
51.
What is the function of the lymphatic system?
a)
Drains tissue fluids, waste products & flights against infection.
b)
Prevent swelling
c)
Removes toxins & waste 
d)
Fights against infection 
52.
These cells are responsible for identifying the "enemy" in an immune response.
a)
Killer-T Cells
b)
B Cells
c)
Helper-T Cells
d)
Antibodies
53.
A nonspecific defensive response of the body to tissue injury characterized by dilation of blood vessels and swelling.
a)
immunity
b)
interferon
c)
immunization
d)
inflammation
54.
When the exaggerated reaction of the immune system to an allergen causes extensive bronchial constriction, mucus production, and excessive capillary permeability, resulting in circulatory collapse and death, this is known as:
a)
Seizure
b)
Anaphylactic Shock
c)
Medical Coma
d)
Hyperventilation
55.
If the infection gets too serious what cell comes to aid?
a)
B cells
b)
T cells
c)
dendritic cell
d)
phagacytes
56.
What is innate immunity?
a)
a type of general protection that humans have. Many of the germs that affect other species don't harm us.
b)
immunity that is "borrowed" from another source and it lasts for a short time
c)
This type of immunity develops throughout our lives
57.
What is adaptive immunity?
a)
a type of general protection that humans have. Many of the germs that affect other species don't harm us.
b)
 immunity that is "borrowed" from another source and it lasts for a short time
c)
This type of immunity develops throughout our lives
58.
What is passive immunity?
a)
a type of general protection that humans have. Many of the germs that affect other species don't harm us.
b)
 immunity that is "borrowed" from another source and it lasts for a short time
c)
This type of immunity develops throughout our lives
59.

How does AIDS disrupt homeostasis?

a)

It prevents the digestive system from breaking down food.

b)

It weakens the immune system so the body can't fight pathogens.

c)

It stops mitochondria from carrying out cell respiration.

60.

A key part of the humoral immune response is

a)

the attack of cytotoxic T cells on infected host cells.

b)

the production of antibodies by plasma cells.

c)

perforation of infected host cells by perforin.

d)

the attack of phagocytes on living pathogens.

61.

Which of the following cell types is responsible for the humoral immune response?

a)

B cells

b)

neutrophils

c)

natural killer cells

d)

macrophages

62.

Which of the following doesn't contain HIV?

a)

Blood

b)

Breastmilk

c)

Sweat

d)

Seminal & Vaginal fluids

63.
Needs host cell to reproduce.
a)
Virus
b)
Bacteria
c)
Fungus
64.

Symptoms include abnormally high WBC count, fever, strand infections, fatigue & nosebleeds.

a)

anemia

b)

mononucleosis

c)

polycythemia

d)

leukemia

65.
Vaccines stimulate the body to produce...
a)
autoimmune diseases
b)
helper t-cells
c)
fever
d)
antibodies
66.

_______ response is when Cytotoxic T cells, a type of lymphocytic white blood cell, “target” intracellular pathogens when antigens are displayed on the outside of the cells.

a)

Humoral Response

b)

Cell Mediated Response

67.

In the ___________ response, B cells, also known as B lymphocytes, are a type of white blood cell/lymphocyte. They function in the immunity component of the adaptive immune system by secreting antibodies

a)

Cell Mediate Response

b)

Humoral Response

68.

How do immune cells communicate by cell to cell contact

a)

Mucous : Acidity

b)

MHC : Helper T Cells

c)

Inflammation: Histamine

69.
All of these are part of the innate immune response except: 
a)
B cells
b)
mast cells
c)
natural killer cells
d)
macrophages
70.
These cells bind to antigen presenting cells signaling them to produce cytokines that stimulate B and T cells to divide
a)
helper T cell
b)
mast cell
c)
cytotoxic T cell
d)
plasma cells
71.

) An epitope is

a)

part of the interferons that penetrate foreign cells.

b)

a protein protruding from the surface of B cells.

c)

two structurally similar antibodies dissolved in the blood plasma

d)

that part of an antigen that actually binds to an antigen receptor.

72.

A patient who can produce antibodies against some bacterial pathogens, but not against viral infections, probably has a disorder in his

a)

B cells

b)

plasma cells.

c)

t cells

d)

macrophages

73.

Antibodies are

a)

carbohydrates.

b)

amino acids.

c)

lipids.

d)

proteins.

74.
These molecules are responsible for inducing a fever during the innate immune response. 
a)
interferons
b)
cytokines
c)
complement
d)
antibodies
75.

The MHC (major histocompatibility complex) is important in …

a)

tracking viral invaders.

b)

identifying bacterial pathogens.

c)

recognizing parasitic pathogens.

d)

distinguish self from non-self.

76.

What are plasma cells?

a)

Cells that produce few antibodies.

b)

The cells responsible for immunological memory.

c)

The effector cells of humoral immune response.

d)

The cells responsible for phagocytosis of foreign organism.

77.

There are three stages of defence against pathogenic bacteria in human immunity system, as listed below. Arrange the stages in a CORRECT sequence.

I. The phagocytic action of macrophages.

II. The action of T-cells and antibody-producing cells.

III. The production of antimicrobial enzymes and Ig A by the mucous membranes

a)

I, II, III

b)

II, III, I

c)

III, II, I

d)

II, I, II

78.

If a person's bone marrow were destroyed by radiation, which of the following cells could NOT be produced?

I. T cells

II. B cells

III. Plasma cells

a)

I only

b)

I and II only

c)

II and III only

d)

I, II and III

79.

Which one of these are NOT antigen antibody interaction

a)

Opsonization

b)

Neutralization

c)

Combination

d)

Activation of complement system

80.

All of the followings are lymphoid organs except for

a)

Spleen

b)

Thymus

c)

Pancreas

d)

Bone marrow

81.

Interleukin-1 is secreted by

a)

Helper T cell

b)

Killer cell

c)

B cell

d)

Antigen Presenting Cell

82.

What is the purpose secreting interleukin-2

a)

To activate B cell

b)

To activate Plasma cell

c)

To activate Helper T cell

d)

To activate

83.
What function does mucus play in the immune system?
a)
traps foreign particles from entering the body
b)
moistens food
c)
produces WBCs
d)
acts as a lubricant

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