wayground logo

Free Printable Worksheets

Font size

S
M
L
XL
Worksheets

Human Heredity (H)

Total questions: 90

Worksheet time: 1hrs 25mins

Name
Class
Date
1.
What is an autosome?
a)
automobile built for one person
b)
chromosome that does not determine gender
c)
chromosome that does determine gender
d)
a plant because they do photosynthesis
2.
How many TOTAL chromosomes do humans have?
a)
2
b)
44
c)
46
d)
23
3.
This is a picture of chromosomes arranged in homologous pairs---what is it called? 
a)
Genome
b)
Punnett Square 
c)
Karyotype
d)
Autosomal cells 
4.
Looking at the karyotype, is this person male or female?
a)
There is no way to tell from a karyotype.
b)
Male 
c)
Female 
d)
This person has a genetic disorder
5.
A gene located on the sex chromosome
a)
autosome
b)
sex-linked
c)
genetic disorder
d)
sex gene
6.
This is a chart used to analyze the pattern of inheritance that shows the relationships in a family.
a)
pedigree
b)
genotype
c)
genome
d)
karyotype
7.
Which of the following disorders is a direct result of nondisjunction?
a)
sickle cell disease 
b)
Turner's syndrome
c)
Huntington's disease
d)
cystic fibrosis
8.
The genotype of the affected son and daughter at the bottom of this pedigree...
a)
homozygous dominant
b)
homozygous recessive
c)
heterozygous
d)
Can't tell
9.
This trait always shows up in an organism when the allele is present
a)
dominant allele
b)
codominance
c)
probability
d)
recessive allele
10.
This trait is hidden whenever the dominant allele is present
a)
dominant allele
b)
codominance
c)
recessive allele
d)
Punnett Square
11.
Non disjunction of chromosomes occurs during
?
a)
Meiosis
b)
Mitosis
c)
Replication 
12.
Mutations affect the ________ of a protein. Because of this the proteins ______ is affected as well. 
a)
gene, function 
b)
sequence, gene
c)
shape,function
13.
a)
Male
b)
Female
14.

About how many genes does the human genome contain?

a)

46

b)

1 billion

c)

200-300

d)

20,000-30,000

15.
When can a mutation be passed on to offspring?
a)
only when the mutation is present during or occurs during mitosis
b)
only when the mutation is present during or occurs during meiosis
c)
when the mutation occurs during mitosis or meiosis
d)
when the mutation occurs in somatic cells
16.
What chromosome is affected by Down's Syndrome?
a)
23
b)
18
c)
13
d)
21
17.

What percentage of sperm cells contain an "X" chromosome?

a)

0%

b)

50%

c)

100%

d)

75%

18.

A dominant pedigree is shown. What is the genotype of II-1?

a)

AA

b)

Aa

c)

aa

19.

A dominant pedigree is shown. What are the potential genotypes of individual I-2?

a)

Aa

b)

aa

c)

AA or Aa

d)

AA

20.

An X-linked recessive trait is shown. Who is more likely to have this disease?

a)

males

b)

females

21.

In the pedigree shown, what is the genotype of individual 1?

a)

AA

b)

AA or Aa

c)

aa

d)

aa or AA

22.

An autosomal recessive trait is shown. How many male individuals have a genotype "aa"?

a)

7

b)

24

23.

In which type of cell division do chromosomal mutations occur?

a)

Mitosis

b)

Meiosis

24.

The proteins found on the surface of RBCs that allow us to type blood as A, B, O or AB are called

a)

antigens

b)

antibodies

c)

aggluntates

d)

Rh factors

25.

What is produced by your body in response to foreign antigens, such as the wrong type of blood?

a)

agglutinates

b)

clotting factors

c)

phagocytes

d)

antibodies

26.
If two parents are heterozygous for type A blood, what is the probability that their offspring would have type O blood?
a)
100 %
b)
75%
c)
50%
d)
25%
27.
What types of blood can a person with AB RECEIVE?
a)
B only
b)
AB, A, B, O
c)
AB and O only
d)
A only
28.
What type of blood is the universal donor?
a)
O
b)
AB
29.
An individual's blood type is determined by
a)
environment
b)
genetics
c)
both environment and genetics
d)
your children's blood type
30.

In the image above, what is the percentage of the offspring has the possibility of inheriting blood type O?

a)

0%

b)

25%

c)

50%

d)

100%

31.
Which blood type is the UNIVERSAL DONOR?
a)
O+
b)
O-
c)
AB+
d)
AB-
32.

What inheritance patterns makes the blood type AB possible?

a)

incomplete dominance

b)

multiple alleles

c)

codominance

d)

total dominance

33.
Determine the sex of the individual whose karyotype is displayed in the image.
a)
female
b)
male
34.
Determine the sex of the individual whose karyotype is displayed in the image.
a)
female
b)
male
35.
A pair of identical chromosomes shown in a karyotype, one inherited from mom, and one inherited from dad are called
a)
sister chromotids
b)
centromeres
c)
homologous chromosomes
d)
autosomes
36.
A sperm contains
a)
Both an X and a Y chromosome
b)
Two X chromosomes
c)
An X OR a Y chromosome
d)
only a Y chromosome
37.
An egg contains
a)
22 autosomes and an X chromosome
b)
22 autosomes and an Y chromosome
c)
44 autosomes and 2 X chromosomes
d)
44 autosomes and an X and a Y chromosome
38.
Chromosome pairs 1-22 are referred to as
a)
sex chromosomes
b)
sister chromatids
c)
a karyotype
d)

autosomes

39.
A picture of paired chromosomes is a
a)
sister chromatid
b)
centromere
c)
syndrome
d)
karyotype
40.
What is the haploid number for this Karyotype?
a)
26
b)
27
c)
52
d)
54
41.
What would indicate a human male?
a)
XX
b)
X
c)
XY
d)
XXY
42.
A person with Turner syndrome has only one X chromosome. This means one of their gametes was missing a chromosome.
Which of the following is why gametes sometimes lack a complete chromosome?
a)
Incomplete dominance
b)
Nondisjunction
c)
Inversion mutation
d)
Substitution mutation
43.

SELECT ALL THAT APPLY:

a)

Male

b)

Female

c)

No chromosomal abnormalities

d)

Trisomy 21

44.

SELECT ALL THAT APPLY:

a)

Male

b)

Female

c)

No chromosomal abnormalities

d)

Trisomy 21

45.

Which of the following is an autosomal recessive disorder?

a)

Huntington's disease

b)

sickle cell anemia

c)

colorblindness

d)

Hemophilia

46.

Which of the following is a autosomal dominant disorder?

a)

Huntington's

b)

Cystic fibrosis

c)

Hemophilia

d)

Sickle cell anemia

47.

Which of the following is a sex-linked disorder?

a)

Hemophilia

b)

Sickle cell anemia

c)

Cystic fibrosis

d)

Huntington's

48.

Which of the following is NOT a chromosomal disorder?

a)

Turner's syndrome

b)

Downs syndrome

c)

Klinefelter's syndrome

d)

Huntington's

49.
Which disease or disorder is caused by the inheritance of two mutated alleles?
a)
Down Syndrome
b)
Colorblindness
c)
Cystic Fibrosis
d)
Hemophilia
50.
Which genetic disorder or disease is a sex-linked trait and carried on the X chromosome?
a)
Cystic Fibrosis
b)
Sickle-cell Disease
c)
Hemophilia
d)
Down Syndrome
51.
What chromosome is affected by hemophilia?
a)
x
b)
y
c)
21
d)
13
52.

Why is Down syndrome called trisomy 21

a)

The person has 21 pairs of chromosomes instead of 23.

b)

The person has an abnormal gene on chromosome 21.

c)

The syndrome is caused by having 21 pairs of autosomes.

d)

The syndrome results from an extra chromosome 21.

53.

What is the effect of sickle-cell anemia?

a)

blocked respiratory pathways

b)

decreased neurological functions

c)

inefficient oxygen transportation

d)

susceptibility to contracting malaria

54.

A man carrying the allele for Huntington’s disease marries a woman who is homozygous recessive for the allele. What is the probability that their offspring will develop Huntington’s disease?

a)

25 percent

b)

50 percent

c)

75 percent

d)

100 percent

55.

Which disorder is characterized by the inability to break down a proteins (specifically phenylalanine) and can be treated by a special diet?

a)

Huntington's

b)

Tay Sachs

c)

Cystic fibrosis

d)

PKU

56.

Which disorder is characterized by the inability to break down lipids in the brain and nervous system and usually results in death by ages 3-5?

a)

Tay-Sachs

b)

Cystic fibrosis

c)

Huntington's

d)

PKU

57.
What do half colored symbols represent?
a)
The individual is a carrier (heterozygous).
b)
The individual expresses the trait.
c)
The individual has both recessive alleles.
d)
The individual has both dominant alleles.
58.

Disease that caused the body to produce thick and sticky mucus that can clog the lungs and obstruct the pancreas.

a)

hemophilia

b)

cystic fibrosis

c)

tay sachs

d)

sickle cell anemia

59.

Why do sex-linked disorders affect men more than women?

a)

males only have 1 X chromosome

b)

males do not have an X chromosome

c)

girls always have 2 defective X chromosomes

d)

males only have Y chromosomes

60.

Identify the substitution mutation that results in an abnormally shaped protein and that causes a reduced ability to bind and transport oxygen.

a)

Cystic fibrosis

b)

Sickle cell anemia

c)

Huntington's

d)

Hemophilia

61.

45 + XX

a)

Klinfelter's syndrome

b)

Male Down's Syndrome

c)

Female Down's Syndrome

d)

Turner's Syndrome

62.
How many base pairs (bp) are in the human genome?
a)
1 billion bp
b)
4 billion bp
c)
3 billion bp
d)
3.5 billion bp
63.

4. About how many genes are there in the human genome?

a)

a) 2,500

b)

b) 20,500

c)

c) 205,000

64.

1. What is a genome?

a)

a) A group of related genes

b)

b) The complete set of a species' genes

c)

c) Someone who studies genes

65.

What is a genetic mutation

a)

the making of a zombie

b)

any change in the DNA base pairs

c)

the process of duplicating the DNA in a cell

66.

A substitution mutation occurs when

a)

a base pair is missing from the DNA strand

b)

a base pair is added to the DNA strand

c)

a base pair is replaced with a different base pair

67.

An insertion/additon mutation occurs when

a)

a base pair is missing from the DNA strand

b)

a base pair is added to the DNA strand

c)

a base pair is replaced with a different base pair

68.

A deletion mutation occurs when

a)

a base pair is missing from the DNA strand

b)

a base pair is added to the DNA strand

c)

a base pair is replaced with a different base pair

69.

A mutation that helps an organism survive and reproduce

a)

harmful mutation

b)

helpful mutation

c)

neutral mutation

70.

A mutation that decreases an organism's ability to survive and reproduce

a)

harmful mutation

b)

helpful mutation

c)

neutral mutation

71.

Mutations are...

a)

Changes in the sequence of DNA

b)

Broken chromosomes

c)

Bad genes

72.

Mutations can benefit humans because they can:

a)

Cause illness

b)

Make an organism more suited to live in its environment.

c)

Make organisms live shorter lives

d)

Cause organisms to grow extra limbs.

73.
What causes mutations?
a)
Mistakes in replication or environmental substances
b)
The amino acids
c)
Passed down by genetics
d)
It's how your born
74.

Mutations are random.

a)

True

b)

False

75.

Why are insertion and deletion mutations so harmful?

a)

They change all of the codons from the mutation on down the line, which changes the amino acid sequence

b)

They insert things that an organism doesn't need.

c)

They often delete things that organisms need.

d)

Insertion and deletions are not any more harmful than substitution mutations.

76.
Why is the order of amino acids so important?
a)
The order of amino acids dictates what shape the protein will fold into.
b)
It is not important. The protein folding chamber will force the protein to fold into the correct shape.
77.

A nucleotide base is inserted or deleted shifting the entire DNA sequence. Entire protein will be changed.

a)

Substitution Mutation

b)

Silent Mutation

c)

Frameshift Mutation

d)

Translocation

78.

A substitution mutation that has no effect

on amino acids sequence

a)

Insertion Mutation

b)

Translocation

c)

Silent Mutation

d)

Deletion Mutation

79.
A mutation that does NOT show up through protein function is called
a)
deletion mutation
b)
inversion mutation
c)
silent mutation
d)
transverse mutation
80.
DNA molecule segment is : TTACGCAAG
The mutated DNA segment is TTACGCAAC. This is an example of ___ mutation.
a)
Base Substitution
b)
Base Insertion
c)
Base Inversion
d)
Translocation
81.
What type of gene mutation has occurred here? Normal-
AGA-TTC-ATA-GCG
Mutant-
AGA-TTC-AAT-AGC-G
a)
deletion frameshift
b)
insertion frameshift
c)
substitution
d)
nonsense
82.

Mutations are__________

a)

Harmful

b)

Harmful or beneficial

c)

Neutral

d)

Harmful, neutral, or beneficial

83.

A piece of one chromosome detaches and reattaches to a different chromosome

a)

deletion

b)

duplication

c)

inversion

d)

translocation

84.

The chromosomal mutation shown in the image is a

a)

deletion

b)

duplication

c)

inversion

d)

translocation

85.

The chromosomal mutation shown in the image is a

a)

deletion

b)

duplication

c)

inversion

d)

translocation

86.

The chromosomal mutation shown in the image is a

a)

deletion

b)

duplication

c)

inversion

d)

translocation

87.

The chromosomal mutation shown in the image is a

a)

deletion

b)

duplication

c)

inversion

d)

translocation

88.

Nondisjunction

a)

When a segment of a chromosome breaks off.

b)

When a segment of a chromosome breaks off, flips, and reattaches.

c)

When a segment of a chromosome is copied or doubles.

d)

When a segment of a chromosome breaks and attaches to a non homologous chromosome.

e)

When entire chromosomes don't separate evenly during meiosis.

89.
The following karyotype illustrates an example of which syndrome?
a)
Turner's Syndrome
b)
Klienfelter's Syndrome
c)
Edward's Syndrome
d)
Down Syndrome
90.
Notice the abnormal 23rd chromosome.  This individual suffers from which chromosomal genetic disorder?
a)
Klienfelter's Syndrome
b)
Down Syndrome
c)
Cris-du-Chat Syndrome
d)
Andrew's Syndrome

Similar Resources on Wayground

SC.912.L.18.9 - Photosynthesis & Cellular Respiration

88 questions

SC.912.L.18.9 - Photosynthesis & Cellular Respiration

quiz

Worksheet

•

9th - 11th Grade

APES Review

90 questions

APES Review

quiz

Worksheet

•

9th - 12th Grade

Biology Roots

93 questions

Biology Roots

quiz

Worksheet

•

9th Grade

Viruses and Taxonomy

90 questions

Viruses and Taxonomy

quiz

Worksheet

•

9th - 10th Grade

Cells, Cell Parts, and Cell Transport Review for TEST 2

88 questions

Cells, Cell Parts, and Cell Transport Review for TEST 2

quiz

Worksheet

•

9th Grade

Unit 2 Test Review

85 questions

Unit 2 Test Review

quiz

Worksheet

•

8th - 10th Grade

SOL Review - BIO.5 DNA & Genetics

85 questions

SOL Review - BIO.5 DNA & Genetics

quiz

Worksheet

•

9th - 12th Grade

Biology Spring 2022 Final Review

95 questions

Biology Spring 2022 Final Review

quiz

Worksheet

•

9th - 10th Grade