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Drugs acting on CNS - 2 & NSAIDs

Total questions: 50

Worksheet time: 27mins

Name
Class
Date
1.

All of the following are bronchodilators except :

a)

Sevoflurane

b)

Isoflurane

c)

Nitrous oxide

d)

Halothane

2.

Diffusion hypoxia is avoided by:

a)

Combining Nitrous oxide with halothane

b)

Giving 100% O2 before nitrous oxide is administered

c)

Giving 100% O2 after nitrous oxide is discontinued

d)

Reducing the dosage of nitrous oxide

3.

General anesthetic with antiemetic effect:

a)

Thiopentone

b)

Halothane

c)

Propofol

d)

Ketamine

4.

Drugs having redistribution:

a)

Thiopentone

b)

Propofol

c)

Ketamine

d)

Etomidate

5.

GA drug indicated in hypovolemia:

a)

Ketamine

b)

Etomidate

c)

Thiopentone

d)

Propofol

6.

Dexmedetomidine is a :

a)

Central α1 antagonist

b)

Central α1 agonist

c)

Central α2 antagonist

d)

Central α2 agonist

7.

Drug given to hasten gastric emptying before surgery:

a)

Domperidone

b)

Ondansetron

c)

Omeprazole

d)

Lorazepam

8.

Electric cautery is contraindicated in GA with:

a)

Propofol

b)

Halothane

c)

Ether

d)

Methohexitone

9.

Select the false statement about desflurane

a)

Causes hypotension

b)

Not hepatotoxic

c)

d-TC dose can be reduced with it

d)

Causes seizures

10.

Choose the correct statement

a)

Thiopentone causes sympathetic stimulation

b)

Thiopentone causes laryngospasm

c)

Ketamine causes bronchoconstriction

d)

Ketamine has weak analgesic effect

11.

Select the LA with longest duration of action among the following:

a)

Articaine

b)

Procaine

c)

Tetracaine

d)

Mepivacaine

12.

Factors affecting onset of action of LAs:

a)

Lipid solubility

b)

Rate of diffusion

c)

pKa

d)

Plasma protein binding

13.

Drug useful in ventricular arrythmias

a)

Bupivacaine

b)

Ropivacaine

c)

Prilocaine

d)

Lignocaine

14.

LA causing mucosal irritation

a)

Procaine

b)

Cocaine

c)

Chlorprocaine

d)

Articaine

15.

LA metabolised in plasma :

a)

Lignocaine

b)

Chlorprocaine

c)

Mepivacaine

d)

Prilocaine

16.

EMLA is used in all except :

a)

Infants

b)

Venesection

c)

Skin grafting

d)

Burns dressing

17.

Anesthesia given for cesarean section in obstetrics

a)

Epidural anesthesia

b)

Spinal anesthesia

c)

Bier's block

d)

Nerve block anesthesia

18.

Propranolol impairs lignocaine clearance by:

a)

Reducing hepatic metabolism

b)

Reducing hepatic blood flow

c)

Reducing absorption from GIT

d)

Reducing distribution in blood

19.

Spinal anesthesia is contraindicated in all except:

a)

Children

b)

Sepsis

c)

Hypertension

d)

Shock

20.

Benoxinate is used for:

a)

Anal mucosa anesthesia

b)

Spinal anesthesia

c)

Corneal anesthesia

d)

IV regional anesthesia

21.

Which of the following is a weak μ receptor antagonist?

a)

Buprenorphine

b)

Pentazocine

c)

Methadone

d)

Tapentadol

22.

Which of the following is a pethidine congener ?

a)

Loperamide

b)

Lacosamide

c)

Dextropropoxyphene

d)

Diphenyl

23.

Drug reaction seen with pethidine but not with morphine :

a)

Respiratory depression

b)

Biliary spasm

c)

Miosis

d)

Tremors

24.

Miosis produced by morphine is due to its action on:

a)

Occulomotor nerve

b)

Edinger-Westphal nucleus

c)

Sphicter pupillae

d)

Dilator pupillae

25.

Morphine acts on pain perception at:

a)

Spinal level

b)

Supraspinal level

c)

Peripheral nerves

d)

Autonomic nerves

26.

Opioid causing NA reuptake inhibition

a)

Tramadol

b)

Pentazocine

c)

Methadone

d)

Buprenorphine

27.

Analgesia is 100 times more potent than morphine for :

a)

Nalbuphine

b)

Fentanyl

c)

Pethidine

d)

Buprenorphine

28.

Drug used in postanesthetic shivering:

a)

Morphine

b)

Codeine

c)

Pethidine

d)

Pentazocine

29.

Opioid antagonist used to treat alcoholism:

a)

Naloxone

b)

Naltrexone

c)

Nalmefene

d)

All of these

30.

Buprenorphine is:

a)

A less potent analgesic than morphine

b)

A drug causing postural hypotension

c)

Used in opioid dependence therapy

d)

Noscapine congener

31.

The NSAID Diflunisal is a:

a)

Salicylic acid derivative

b)

Propionic acid derivative

c)

Enolic acid derivative

d)

Acetic acid derivative

32.

NSAIDs affect normal body temperature

a)

True

b)

False

33.

Which of the following is not seen with Aspirin?

a)

Angioneurotic edema

b)

Bronchospasm

c)

Hypoprothrombinemia

d)

Analgesic neuropathy

34.

NSAIDs with glucocorticoids potentiate

a)

Ulcerogenic effect

b)

Hypersensitivity

c)

Antiplatelet effect

d)

Anti-inflammatory effect

35.

Preferred drug for closure of patent ductus arteriosus

a)

Aspirin

b)

Indomethacin

c)

Ibuprofen

d)

Paracetamol

36.

NSAID used in metastatic cancer pain:

a)

Diclofenac

b)

Ketorolac

c)

Acelcofenac

d)

Piroxicam

37.

Peptic ulcer is rare with:

a)

Etoricoxib

b)

Acetaminophen

c)

Piroxicam

d)

Naproxen

38.

Which of the following drug reactions are seen with acute overdose of paracetamol?

a)

Hepatotoxicity

b)

Nephrotoxicity

c)

Skin rashes

d)

All of these

39.

Which of the following drugs inhibit glutamate release?

a)

Riluzole

b)

Carisoprodol

c)

Baclofen

d)

Methocarbamol

40.

Histamine release is NOT seen with:

a)

Mivacurium

b)

Atracurium

c)

Suxamethonium

d)

Cisatracurium

41.

Most rapid acting skeletal muscle relaxant:

a)

Rapacuronium

b)

Rocuronium

c)

Vecuronium

d)

Mivacurium

42.

Which of the following antibiotics DO NOT potentiate the effects of d-TC?

a)

Aminoglycosides

b)

Ampicillin

c)

Clindamycin

d)

Tetracycline

43.

Effect of skeletal muscle relaxants are increased with all except:

a)

Isoflurane

b)

Ketamine

c)

Myasthenia gravis

d)

Hyperkalemia

44.

Sugammadex blocks the action of

a)

Rocuronium

b)

Vecuronium

c)

Rapacuronium

d)

Pancuronium

45.

Botulinum toxin is used in all except:

a)

Cosmetic procedures

b)

Dystonia

c)

Preanesthetic

d)

Sialorrhoea

46.

Non depolarising NMJ blocker causing ganglionic blockade:

a)

d-TC

b)

Rapacuronium

c)

Pipecuronium

d)

Cisatracurium

47.

Select the neuroprotective drugs :

a)

Piracetam

b)

Piribedil

c)

Gingko biloba

d)

Memantine

48.

Drug used in parkinsonism and stroke

a)

Citicoline

b)

Gingko biloba

c)

Memantine

d)

Galantamine

49.

Drugs used in narcolepsy are all except:

a)

Modafinil

b)

Amphetamine

c)

Dextroamphetamine

d)

Methylphenidate

50.

Which of the following drugs can cause arrhythmias?

a)

Doxapram

b)

Methylphenidate

c)

Atomoxetine

d)

Modafinil

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