Provides coagulation enzymes

(a)  

Ordered nearly to everyone who visit a physician or admitted to hospital

(a)  

Who describe worms in blood in 1657

(a)  

He gave an account to RBC on 1674

(a)  

Described platelets as petites plaques

(a)  

Developed wright stain on 1902

(a)  

Polychromatic mixture of acidic and basic dyes

(a)  

Occupies 1/3 the center of Rbc

(a)  

Often reflected of reduced RBC count and RBC hemoglobin concentration

(a)  

Condition that may lead to hyperviscosity

(a)  

Dilution ration Typical for RBC count

(a)  

Glass pipette designed to 1:200 dilution ratio of RBC

(a)  

A glass counting chamber

(a)  

When Automated particle counters became available

(a)  

First automated counter patented on 1953 was by

(a)  

Joseph and wallace coulter principle

(a)  

Weak solution of K cyanide and K ferricyanide

(a)  

Whole blood is mixed w/ measured Drabkin rgt and hemoglobin is converted to

(a)  

Normal hematocrit

(a)  

A.k.a. packed cell volume

(a)  

Often see between rbc and plasma

(a)  

light-colored layer between the RBCs and plasma.

(a)  

The MCV, volume measurement is recorded in what unit

(a)  

reflects RBC diameter on a Wright-stained blood film.

(a)  

expressed in g/dL

(a)  

reflects RBC staining intensity and amount of central pallor.

(a)  

MCH is expresses in

(a)  

reflects the mass of hemoglobin and parallels the MCHC

(a)  

Extreme RBC volume variability is visible on the Wright-stained blood film as variation in diameter and is called

(a)  

In the Wright-stained blood film, 0.5% to 2% of RBCs exceed the 6- to 8-mm average diameter and stain slightly blue-gray. These are

(a)  

RBC production site

(a)  

closely observed because they indicate the ability of the bone marrow to increase RBC production in anemia due to blood loss or excessive RBC destruction

(a)  

stain used to differentiate and count these young RBCs.

(a)  

are dyes absorbed by live cells

(a)  

Young RBCs contain ribonucleic acid (RNA) and are called (a)   when the RNA is visualized using vital stains.

a loosely related category of cell types dedicated to protecting their host from infection and injury

(a)  

WBCs typical dilution ratio is

(a)  

The normal WBC count ranges

(a)  

A decreased WBC count (fewer than 4500/mL)

(a)  

increased WBC count (more than 11,500/mL)

(a)  

phagocytic cells whose major purpose is to engulf and destroy microorganisms and foreign material, either directly or after they have been labeled for destruction by the immune system

(a)  

An increase in neutrophils is called

(a)  

has many causes, but it is often caused by certain medications or viral infections.

(a)  

describe bands

(a)  

An increase in bands also signals bacterial infection and is customarily called as

(a)  

bright orange-red, regular cytoplasmic granules filled with proteins involved in immune system regulation.

(a)  

elevated eosinophil count is called (a)  

often signals a response to allergy or parasitic infection

(a)  

cells with dark purple, irregular cytoplasmic granules that obscure the nucleus.

(a)  

contain histamines and various other proteins.

(a)  

is rare and often signals a hematologic disease.

(a)  

is an uncontrolled proliferation of WBCs.

(a)  

comprise a complex system of cells that provide for host immunity.

(a)  

often is associated with viral infections.

(a)  

often associated with drug therapy

or immunodeficiency.

(a)  

is more prevalent in people older than 65 years,

(a)  

common form of childhood leukemia

(a)  

is an immature macrophage passing through the blood from its point of origin, usually the bone marrow, to a targeted tissue location.

(a)  

most abundant cell type in the body, more abundant than RBCs or skin cells

(a)  

monocytes comprise a minor component of peripheral blood WBCs.

(a)  

occupy every body cavity; some are motile and some are immobilized.

(a)  

Macrophage tasks are to identify and phagocytose (engulf and consume) foreign particles and assist the lymphocytes in mounting an immune response through the assembly and presentation of (a)  

true blood cells that maintain blood vessel integrity by initiating vessel wall repairs

(a)  

the major cells that control hemostasis

(a)  

a series of cellular and plasma based mechanisms that seal wounds, repair vessel walls, and maintain vascular patency (unimpeded blood flow)

(a)  

have largely replaced visual platelet counting and provide greater accuracy

(a)  

Elevated platelet counts,signal inflammation or trauma but convey modest intrinsic significance.

(a)  

is a rare malignant condition characterized by extremely high platelet counts and uncontrolled platelet production.

(a)  

a common consequence of drug treatment and may be life-threatening.

(a)  

When one of the results from the profiling instrument is abnormal, the instrument provides an indication of this, sometimes called a

(a)  

specialized, demanding, and fundamental CBC activity.

(a)  

To accomplish a blood film examination, the microscopist prepares a (a)   blood film on a glass microscope slide, allows it to dry, and fixes and stains it using Wright or Wright-Giemsa stain

WBCs to determine their percent distribution. This process is referred to as determining the

(a)  

endodermal cells that form the inner surface of the blood vessel

(a)  

key component of hemostasis,

(a)  

employs a complex sequence of plasma proteins, some enzymes, and some enzyme cofactors

(a)  

a third system of enzymes and cofactors digests clots to restore vessel patency, a process called

(a)  

are precursors to RBCs

(a)  

mature to form bands and neutrophils, eosinophils, and basophils

(a)  

produce platelets

(a)  

biopsy specimen, enhanced by (a)   staining, may reveal abnormalities in bone marrow architecture indicating leukemia, bone marrow failure, or one of a host of additional hematologic disorders.

Results of examination of bone marrow aspirates and biopsy specimens are compared with (a)   results generated from the peripheral blood to correlate findings and develop pattern-based diagnoses.

may occasionally be employed to differentiate abnormal myeloid, erythroid, and lymphoid cells.

(a)  

Since 1980, however, (a)   have enabled identification of cell lines by detecting lineage-specific antigens on the surface or in the cytoplasm of leukemia and lymphoma cells

a membrane protein that is present in the megakaryocytic lineage and may be diagnostic for megakaryoblastic leukemia

(a)  

are time-honored stains that in most laboratories have been replaced by flow cytometry immunophenotyping, cytogenetics, and molecular diagnostic techniques

(a)  

time-honored form of molecular technology, is employed in bone marrow aspirate examination to find gross genetic errors

(a)  

a reciprocal translocation between chromosomes 9 and 22 that is associated with chronic myelogenous leukemia

(a)  

t(15;17), a translocation between chromosomes 15 and 17 associated with (a)  

the fastest-growing area of laboratory medicine, enhance and even replace some of the advanced hematologic methods.

(a)  

uses graduated concentrations of saline solutions to detect spherocytes in hereditary spherocytosis or warm autoimmune hemolytic anemia

(a)  

osmotic fragility test uses graduated concentrations of saline solutions to detect spherocytes (RBCs with proportionally reduced surface membrane area) in (a)   or warm autoimmune hemolytic anemia

phenotypically detects an inherited RBC enzyme deficiency causing severe episodic hemolytic anemia

(a)  

used to detect and diagnose sickle cell anemia and other inherited qualitative hemoglobin abnormalities and thalassemias

(a)  

One of the oldest hematology tests and detects inflammation and roughly estimates its intensity

(a)  

An internal standard methodology that supports hematology laboratory applications.

(a)