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BIOCHEM FINAL TEST

Total questions: 110

Worksheet time: 6hrs 30mins

Name
Class
Date
1.

The prokaryotic cell is about the size of a eukaryotic mitochondria.

a)

TRUE

b)

FALSE

2.

The prokaryotic ribosomes float free in the cytoplasm.

a)

TRUE

b)

FALSE

3.

cytoskeleton is

a)

fibrous proteins under the cell membrane

b)

location of protein synthesis

c)

location of most RNA synthesis

d)

location of most protein sorting

4.

ribosomes

a)

location of protein synthesis

b)

location of most RNA synthesis

c)

location of most protein sorting

d)

vesicle that moves molecules between organelles

5.

nucleus

a)

location of most RNA synthesis

b)

location of most protein sorting

c)

vesicle that moves molecules between organelles

d)

location of most protein modifications

6.

Golgi

a)

location of most protein sorting

b)

vesicle that moves molecules between organelles

c)

location of most protein modifications

d)

location of most ATP synthesis

7.

transport vesicle

a)

vesicle that moves molecules between organelles

b)

location of most protein modifications

c)

location of most ATP synthesis

d)

vesicle pinched in from cell membrane

8.

smooth endoplasmic reticulum

a)

location of most protein modifications

b)

location of most ATP synthesis

c)

vesicle pinched in from cell membrane

d)

vesicle that releases molecules from the cell

9.

mitochondria

a)

location of most ATP synthesis

b)

vesicle pinched in from cell membrane

c)

vesicle that releases molecules from the cell

d)

location of most highly digestive enzymes

10.

endosome

a)

vesicle pinched in from cell membrane

b)

vesicle that releases molecules from the cell

c)

location of most highly digestive enzymes

d)

location of protein synthesis

11.

secretory vesicle

a)

vesicle that releases molecules from the cell

b)

location of most highly digestive enzymes

c)

location of most RNA synthesis

d)

location of protein synthesis

12.

lysosome

a)

location of most highly digestive enzymes

b)

location of protein synthesis

c)

vesicle that releases molecules from the cell

d)

location of most protein modifications

13.

-CH3

a)

POLAR

b)

NON-POLAR

14.

-OH

a)

NON-POLAR

b)

POLAR

15.

-NH2

a)

POLAR

b)

NON-POLAR

16.

-CH2CH2CH3

a)

NON-POLAR

b)

POLAR

17.

Water tends to stick to other water molecules. The primary reason for this is due to which attractive force?

a)

hydrogen bonds

b)

hydrophobic interactions

c)

double bonds

d)

disulfide linkages

18.

What is a hydronium ion?

a)

3 water molecules sticking together

b)

water with one of its hydrogens missing.

c)

water with an extra H+

d)

2 water molecules sticking together

19.

To make up a pH=6.86, 0.1M phosphate buffer, using the Henderson-Hasselbach equation, plug in the pH and the pKa for sodium phosphate monobasic (6.86).

What is the concentration of the monobasic relative to the dibasic?

a)

[dibasic]=10*[monobasic]

b)

[monobasic]=[dibasic]

c)

[monobasic]=10*[dibasic]

d)

None of the above

20.

basic relative to the other compound

a)

sodium phosphate dibasic

b)

sodium phosphate monobasic

21.

acid relative to the other compound

a)

sodium phosphate dibasic

b)

sodium phosphate monobasic

22.

-CH3

a)

METHYL

b)

ETHER

c)

ESTHYL

d)

PRIMARY AMINE

23.

C-O-C

a)

METHYL

b)

ETHER

c)

METHYLENE

d)

ALCOHOL

24.

-CH2-

a)

ETHYL

b)

METHYLENE

c)

ALCOHOL

d)

PRIMARY AMINE

25.

C-OH

a)

ALCOHOL

b)

METHYL

c)

ETHYL

d)

PRIMARY AMINE

26.

-CH2-CH3

a)

ETHYL

b)

ALCOHOL

c)

METHYLENE

d)

METHYL

27.

C-NH2

a)

PRIMARY AMINE

b)

METHYL

c)

ALCOHOL

d)

METHYLENE

28.

Glucose and Fructose are what type of isomers?

a)

STRUCTURAL

b)

ROTOMERS

c)

CIS-TRANS

d)

R-S

29.

The type of double bonds found in most unsaturated fatty acids are:

a)

CIS

b)

TRANS

30.

alkene

a)

ALKANE

b)

PRIMARY ALCOHOL

c)

SECONDARY ALCOHOL

d)

ALDEHYDE

31.

ALDEHYDE

a)

PRIMARY ALCOHOL

b)

SECONDARY ALCOHOL

c)

ALDEHYDE

d)

ALKANE

32.

KETONE

a)

SECONDARY ALCOHOL

b)

PRIMARY ALCOHOL

c)

ALDEHYDE

d)

ALKANE

33.

CARBOXYLIC ACID

a)

ALDEHYDE

b)

PRIMARY ALCOHOL

c)

SECONDARY ALCOHOL

d)

ALKANE

34.

carboxylic acid and phosphoric acid

a)

ANHYDRIDE

b)

AMIDE

35.

amine and carboxylic acid

a)

ESTER

b)

AMIDE

c)

ANHYNDRIDE

36.

alcohol and carboxylic acid

a)

ESTER

b)

HEMIACETAL

c)

AMIDE

37.

alcohol and aldehdye

a)

HEMIACETAL

b)

ESTER

c)

ANHYDRIDE

38.

What is a hydronium ion

a)

2 water molecules sticking together

b)

3 water molecules sticking together

c)

water with an extra H+

d)

water with one of its hydrogens missing

39.

Water has which chemical property?

a)

it's slightly polar

b)

it's slightly non-polar

c)

it's very non-polar

d)

it's very polar

40.

The pH of a solution when an acid is half dissociated is the:

a)

pKb

b)

Ka

c)

pKa

d)

pH

41.

Which of the following is contains glucose (a1-4) bond? (pick all that apply)

a)

amylose

b)

sucrose

c)

maltose

d)

lactose

42.

D-glucose is epimerized on carbon #2. What did it become?

a)

L-glucose

b)

D-mannose

c)

D-galactose

d)

D-ribose

43.

Draw glycerol. How many stereoisomers are there?

a)

1 (no chiral carbons)

b)

2 (1 chiral carbon)

c)

4

d)

5

44.

When glucose forms a ring, what happened?

a)

one of the ketone group reacted with the aldehyde

b)

one of the alcohol groups reacted with the aldehyde

c)

one of the alcohol groups reacted with the ketone

d)

All of the above

45.

Which of the following is an epimer of glucose?

a)

amylose

b)

glycogen

c)

fructose

d)

mannose

46.

Which of the following sugars contains only glucose?

a)

lactose

b)

sucrose

c)

maltose

d)

heparin

47.

What biochemical feature is common in cellulose and is not found in glycogen?

a)

alpha 1-4 bonds

b)

alpha 1-1 alpha bonds

c)

beta 1-4 bonds

d)

alpha 1-6 bonds

48.

If a urine sample of a diabetic patient has Copper (II) Nitrate added to it, is heated and as a result a brick red precipitate forms, what most likely happened?

a)

glucose is reduced

b)

glucose is oxidized

c)

glucose is aminated

d)

glucose is phosphorylated

49.

Is D-2-deoxyglucose the same thing as D-2-deoxygalactose?

a)

NO

b)

YES

50.

Draw glyceraldehyde. How many stereoisomers can there be?

a)

1 (NO CHIRAL CARBONS)

b)

2 (1 CHIRAL CARBON)

c)

3

d)

4

51.

Which of the following sugars contains a ketone?

a)

cellulose

b)

glycogen

c)

fructose

d)

glucose

52.

What is another biochemical name for a repeating disaccharide?

a)

sucrose

b)

glycan

c)

peptide

d)

maltose

53.

The enzyme lactase, found in our intestine, breaks which type of bond?

a)

Glc(alpha1-4)

b)

Glc(beta1-4)

c)

Gal(beta1-4)

d)

All of the above

54.

Fructose contains which of the following functional groups? (pick all that applied)

a)

hemiacetal

b)

ketone

c)

alcohol

d)

amine

55.

A patient has tested positive for having reducing sugar in his urine. Which of the following sugars best fits the definition of a reducing sugar? (Select all that apply)

a)

lactose

b)

galactose

c)

maltose

d)

mannose

e)

glucose

56.

Saturated Fat

a)

C16:0

b)

C18:3(delta)9,12,15

c)

C18:2(delta)9,12

d)

C18:1(delta)9

57.

OMEGA 3

a)

C16:0

b)

C18:3(delta)9,12,15

c)

C18:2(delta)9,12

d)

C18:0

58.

omega-6

a)

C18:2(delta)9,12

b)

C18:1(delta)9

c)

C18:0

d)

C20:4(delta)5,8,11,14

59.

saturated fat

a)

C18:0

b)

C20:4(delta)5,8,11,14

c)

C16:0

d)

C18:3(delta)9,12,15

60.

omega-9

a)

C18:1(delta)9

b)

C18:0

c)

C20:4(delta)5,8,11,14

d)

C18:2(delta)9,12

61.

omega-6

a)

C20:4(delta)5,8,11,14

b)

C18:3(delta)9,12,15

c)

C18:1(delta)9

d)

C16:0

62.

Which of the following will have the highest melting point?

a)

C18:0

b)

C18:1

c)

C18:2

d)

C18:3

63.

saturated

a)

no carbon to carbon double bonds

b)

has one carbon to carbon double bond

c)

has two or more carbon to carbon bonds

d)

the last double bond is 3 carbons in from the end

64.

monounsaturated

a)

has one carbon to carbon double bond

b)

has two or more carbon to carbon bonds

c)

the last double bond is 3 carbons in from the end

d)

no carbon to carbon double bonds

65.

polyunsaturated

a)

has two or more carbon to carbon bonds

b)

the last double bond is 3 carbons in from the end

c)

has one carbon to carbon double bond

d)

no carbon to carbon double bonds

66.

omega-3 fatty acid

a)

the last double bond is 3 carbons in from the end

b)

has one carbon to carbon double bond

c)

has two or more carbon to carbon bonds

d)

no carbon to carbon double bonds

67.

an unsaturated fatty acid has which of the following functional groups.

a)

ester

b)

alkene

c)

carboxylic acid or a carboxylate

d)

alkane

e)

ether

68.

Most glycolipids have which of the following groups?

a)

oligosaccharides

b)

ketone

c)

alkane

d)

amide

e)

sphingosine

69.

If grease from cooking clogs your kitchen sink, which of the following agents is most likely to degrade and disolve the triglyceride component of this grease?

a)

NaOH

b)

alcohol

c)

HCl

d)

water

70.

Draw a typical phosphodiglyceride. Which of the following funtional groups would be found on a phosphodiglyceride with a choline head group?

a)

Ester

b)

Quaternary Amine

c)

Alkene

d)

Alkane

e)

Phosphoester

71.

Which of the following are lysosomal lipid storage disorders?

a)

Tay-Sachs disease

b)

Sanhoff's diease

c)

Gaucher's disease

d)

I-Cell Disease

e)

Niemann-Pick and Fabry's diease

72.

Which of the following is derived from cholesterol?

a)

Vitamin A

b)

Vitamin B1

c)

Vitamin B2

d)

Vitamin D

73.

Fatty Acid

a)

CH3(CH2)xCOOH

b)

Similar to a phosphodiglyceride but with an ether at position 1

c)

Glycerol esterified to 2 fatty acids and to a phosphate, esterified to choline or one of several other small molecules with an alcohol group

d)

has repeating 5 carbon units

74.

Plasmalogen

a)

Similar to a phosphodiglyceride but with an ether at position 1

b)

Glycerol esterified to 2 fatty acids and to a phosphate, esterified to choline or one of several other small molecules with an alcohol group

c)

has repeating 5 carbon units

d)

Glycerol esterified to 3 fatty acids

e)

has 4 fused rings

75.

Phosphodiglyceride

a)

Glycerol esterified to 2 fatty acids and to a phosphate, esterified to choline or one of several other small molecules with an alcohol group

b)

has repeating 5 carbon units

c)

Glycerol esterified to 3 fatty acids

d)

Similar to a phosphodiglyceride but with a serine rather than a glycerol and a C-C bond at position 1 and a amide at position 2

76.

Isoprenoids

a)

has repeating 5 carbon units

b)

has repeating 5 carbon units

c)

has 4 fused rings

d)

CH3(CH2)xCOOH

77.

Triglyceride

a)

Glycerol esterified to 3 fatty acids

b)

has 4 fused rings

c)

Similar to a phosphodiglyceride but with an ether at position 1

d)

Similar to a phosphodiglyceride but with a serine rather than a glycerol and a C-C bond at position 1 and a amide at position 2

78.

Steriod

a)

has 4 fused rings

b)

Similar to a phosphodiglyceride but with a serine rather than a glycerol and a C-C bond at position 1 and a amide at position 2

c)

Glycerol esterified to 3 fatty acids

d)

Similar to a phosphodiglyceride but with an ether at position 1

79.

Sphingolipid

a)

Similar to a phosphodiglyceride but with a serine rather than a glycerol and a C-C bond at position 1 and a amide at position 2

b)

Glycerol esterified to 3 fatty acids

c)

has repeating 5 carbon units

d)

Glycerol esterified to 2 fatty acids and to a phosphate, esterified to choline or one of several other small molecules with an alcohol group

80.

Glucose and Fructose are what type of isomers?

a)

rotomers

b)

R-S

c)

structural

d)

cis-trans

81.

The hydrogens of water will mostly hydrogen bond to the non-bonding electron pairs of which atoms? (Pick more than one answer.)

a)

nitrogen

b)

neon

c)

oxygen

d)

carbon

82.

What is the side group on “G”?

a)

-CH3

b)

-CH(CH3)2

c)

-CH2-OH

d)

-H

83.

Which of the following amino acids is aromatic?

a)

K

b)

A

c)

Q

d)

F

84.

Which amino acid has a hydrogen as its side group?

a)

Glycine

b)

Phenylalanine

c)

Valine

d)

Glutamate

85.

What is a zwitterion?

a)

A molecule with positive charges

b)

A molecule with equal numbers of positive and negative charges at the same time

c)

A molecule with negative charges

86.

There are 26 standard amino acids.

a)

TRUE

b)

FALSE

87.

Which level of Protein organization is held together only by hydrogen bonding?

a)

PRIMARY

b)

SECONDARY

c)

TEARTIARY

d)

QUATERNARY

88.

Mad Cow Disease is caused by:

a)

A virus that causes holes in the brain tissue

b)

Prion proteins that have refolded

c)

A toxin in tainted beef that blocks the brains ability to synthesize prion proteins.

d)

Prion proteins that have become cross-linked to other prion proteins

89.

The primary force that holds most tertiary structures together are:

a)

Ionic bonds

b)

Hydrophobic forces

c)

Covalent bonds

d)

Hydrogen bonds

e)

Salt bridges

90.

Which of the following bonds has the most restricted rotation compared to the others?

a)

phi

b)

psi

c)

peptide

91.

In sickle cell anemia, why does the HbS (sickle hemoglobin) cause sickling of the cell?

a)

It has lost positive charges on it causing it to form rod shaped crystals inside the cell.

b)

It has additional positive charges on it that push out the edges of the cell.

c)

It has additional negative charges on it that push out the edges of the cell.

d)

It has lost both positive and negative charges on it causing it to form rod shaped crystals inside the cell.

e)

It has lost negative charges on it causing it to form rod shaped crystals inside the cell.

92.

Which amino acid is the most abundant in our blood?

a)

Tyrosine

b)

Arginine

c)

Glutamine

d)

Glycine

93.

What is the one letter code for the aromatic amino acid with the largest molecular weight?

a)

W

b)

G

c)

A

d)

M

94.

Amino Acid Sequence

a)

PRIMARY STRUCTURE

b)

SECONDARY STRUCTURE

c)

TERTIARY STRUCTURE

d)

QUATERNARY STRUCTURE

95.

Alpha Helix and Beta Sheet

a)

SECONDARY STRUCTURE

b)

PRIMARY STRUCTURE

c)

TERTIARY STRUCTURE

d)

QUATERNARY STRUCTURE

96.

Protein Folding

a)

PRIMARY STRUCTURE

b)

SECONDARY STRUCTURE

c)

TERTIARY STRUCTURE

d)

QUATERNARY STRUCTURE

97.

Protein Assembly

a)

PRIMARY STRUCTURE

b)

SECONDARY STRUCTURE

c)

TERTIARY STRUCTURE

d)

QUATERNARY STRUCTURE

98.

The prokaryotic cell is about the size of a eukaryotic mitochondria.

a)

TRUE

b)

FALSE

99.

The prokaryotic ribosomes float free in the cytoplasm.

a)

TRUE

b)

FALSE

100.

Which of the following functional groups increase the water solubility of a molecule.

a)

amine

b)

phenyl

c)

carboxylate

d)

alcohol

101.

What is the pH of a neutral solution.

a)

1

b)

2

c)

6

d)

7

e)

12

102.

Is D-2-deoxyglucose the same thing as D-2-deoxygalactose?

a)

YES

b)

NO

103.

Which of the following is a 5 carbon sugars?

a)

glycogen

b)

ribose

c)

manose

d)

fructose

104.

When glucose forms a ring, what happened?

a)

one of the alcohol groups reacted with the aldehyde

b)

one of the alcohol groups reacted with the ketone

c)

one of the ketone group reacted with the aldehyde

d)

All of the above

105.

Which of the following sugars contains only glucose?

a)

maltose

b)

glucose

c)

heparin

d)

sucrose

106.

Most amino acids are composed of:

a)

D-amino acids

b)

L-amino acids

107.

What is the one letter abbreviation for Tryptophan?

a)

W

b)

F

c)

A

d)

M

108.

The amino acid "S" has an alcohol on its side group.

a)

TRUE

b)

FALSE

109.

Which of the following amino acids has a acid side group?

a)

A

b)

C

c)

E

d)

G

110.

Which of the following amino acids is aromatic?

a)

E

b)

F

c)

H

d)

G

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