WorksheetsBB ASSESSMENT QUIZ MODULE
Total questions: 50
Worksheet time: 24mins
All of the following were approaches in naming antigens before the ISBT except?
Adopting the name of the country of the antibody producer
Using the name of the scientist discovering the antigen,
Derivation of the name of the first antibody maker or reactive donor
Deriving the antigen name based on ISBT working party
ISBT Designation: 700
Blood group system antigens
Blood group collection antigens
High incidence series antigens
Low incidence series antigens
ISBT Designation: 201
Blood group system antigens
Blood group collection antigens
High incidence series antigens
Low incidence series antigens
It is the description of which antigens are present o n
an individual s RBCs and simply indicates the results of
serologic tests on those RBCs
Genotype
Allelles
Phenotype
Genes
Based on the ISBT guidelines, each antigen is given a six digit identification number and the first three digits represents all of the following except?
Blood group system
Blood Groupg Collection
Low and High Incidence series
Antigen
The Lutheran Blood Group System has an ISBT no. assigned as?
004
003
006
005
The Lewis Blood Group System has an ISBT no. assigned as?
004
007
002
005
It is composed of antigens produced by alleles at a single gene locus or at loci so closely linked that crossing over does not occur.
Blood Group Collection
High Incidence Series
Low Incidence Series
Blood Group System
What is the ISBT number for the Lu3 antigen?
005001
005002
005003
005004
What is the ISBT number for the k antigen?
004001
004002
005001
005002
What is the ISBT number for the P1 antigen?
003001
003002
003003
003004
The Lutheran Blood Group is found in chromosome no. ?
9
1
4
19
All of the following blood group antigens belongs to carbohydrate group except?
ABO
I
GLOB
KEL
The only blood group systems wherein antigens are adsorbed from plasma.
JK
KEL
LE
RH
This blood group system has antigens that belongs to multi-pass membrane protein.
JK
KEL
LE
RH
These are rare alleles that do not encode any antigen.
Dominant allele
Recessive allele
Silent allele
Codominant allele
Antigens with prevalence of less than 1% in the general
population.
Low Incidence
High Incidence
Blood Group Collection
Blood Group Sytem
Antigens with prevalence of less than 90% in the general
population.
Low Incidence
High Incidence
Blood Group Collection
Blood Group Sytem
AKA nuisance antibodies
Clinically Nonsignificant Antibodies
Clinically Significant Antibodies
IgG antibody
Warm Reacting antibodies
Named after the first antibody producer reported by Mourant in 1946
KEL
LE
FY
JK
ISBT 209 is assigned to which blood group collection?
COST
I
ER
GLOB
ISBT 700005 was assigned to what low incidence series?
By
Bi
Pta
Jea
The most common Lewis Phenotype among whites:
Le (a+ b+)
Le (a- b+)
Le (a- b-)
Le (a+ b+)
Lewis phenotype of fetus.
Le (a+ b+)
Le (a- b+)
Le (a- b-)
Le (a+ b+)
The most common Lewis Phenotype among Asians:
Le (a+ b+)
Le (a- b+)
Le (a- b-)
Le (a+ b+)
It serves as the epitope for the tumor marker CA 19-9 found in gastrointestinal and other malignancies.
Sialyl Lea
Ley
Leb
H
Jsa and Jsb are antigens that belongs to:
Kidd
Lewis
Kell
Duffy
Kell antigen expression is dependent upon the presence of the?
XK protein
KX protein
Kk protein
KK protein
Aside form ABO and Rh antibodies, ___is the most common antibody seen in the blood bank.
Anti-Jka
Anti-K
Anti-Lua
Anti-Lea
When RBCs lack expression of all Kell antigens but have the
K x antigen, this is called?
Kell null/Ko
Macleod Phenotype
Duffy null
Lu null
When RBCs lack Kx and another high prevalence antigen, Km (K 20 and have marked depression of all other Kell antigens, this is called?
Kell null/Ko
Macleod Phenotype
Duffy null
Macleod Syndrome
It was named after a multiply transfused hemophiliac who was found to have the first described example of anti Fya.
KEL
LU
FY
LE
The most prevalent Duffy phenotype among blacks
Fy (a+b-)
Fy (a-b-)
Fy (a+b+)
Fy (a-b+)
The most prevalent Duffy phenotype among chinese nationals.
Fy (a+b-)
Fy (a-b-)
Fy (a+b+)
Fy (a-b+)
Indivduals with these phenotype can resist infection with
Plasmodium knowlesii and P vivax.
Fy (a+b-)
Fy (a-b-)
Fy (a+b+)
Fy (a-b+)
Antigens of this blood group system are destroyed during enzyme treatment.
KEL
LU
LE
FY
It results from the interaction of Rh and Duffy genes and usually not present on Rh null RBCs.
Fy3
Fy5
Fy6
Fya
Fyb
Receptor for P. vivax.
Fy3
Fy5
Fy6
Fya
Fyb
This antibody is found in the serum of an Fy(a-b-)individuals.
Anti-Fya
Anti-Fyb
Anti-Fy5
Anti-Fy3
Anti-Fy6
It is a simple and straightforward system consisting of only
three antigens.
KEL
JK
FY
LE
Antigens belonging to this blood group system are urea
transporter.
KEL
JK
FY
LE
Its antibodies are difficult to detect serologically because they are found in combination with other antibodies.
KEL
JK
FY
LE
Have a notorious reputation in blood bank as a common cause of delayed hemolytic transfusion reaction.
Kel antibodies
Kidd antibodies
Lewis antibodies
Duffy antibodies
This blood group system was discovered on a patient with lupus in 1945.
KEL
FY
JK
LU
LE
This antigen was assigned to the Globoside blood group system.
P
Luke and PX2
Pk
P1
These antigens have been found in plasma as glycosphingolipids and as glycoproteins in hydatid cyst
fluid.
P1 and P
P and Pk
P1 and Pk
All of the above
This antibody was formerly known a anti Tja
Anti-P1
Anti-P1Pk
Anti-PP1Pk
Anti-P
Associated with Paroxysmal Cold Hemoglobinuria.
Anti-P1
Anti-P1Pk
Anti-PP1Pk
Anti-P
Auto-anti-P
First described in the serum of Mrs Jay, a p individual with adenocarcinoma of the stomach.
Anti-P1
Anti-P1Pk
Anti-PP1Pk
Anti-P
Auto-anti-P
A receptor for shiga toxins, which cause shigella dysentery and E coli associated hemolytic uremic syndrome
P1 antigen
Pk antigen
PP1Pk antigen
P antigen
