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GLYCOLYSIS, TCA, ETC

Total questions: 60

Worksheet time: 20mins

Name
Class
Date
1.
This glycolysis process happens in the presence of oxygen.
a)
Anaerobic
b)
Aerobic
c)
ETC
d)
Kreb's Cycle
2.
A 43-year-old man presented with symptoms of weakness, fatigue, shortness of breath, and dizziness. His hemoglobin level was less than 7 g/dl (normal for a male being greater than 13.5 g/dl). Red blood cells isolated from the patient showed abnormally low level of lactate production. A deficiency of which one of the following enzymes would be the most likely cause of this patient’s anemia?
a)
Phosphofructokinase
b)
Pyruvate kinase
c)
Hexokinase
d)
Lactate dehydrogenase
3.
A conversion of pyruvate to glucose.
a)
Gluconeogenesis
b)
ETC
c)
ATP
d)
Secret
4.

Biochemistry is the basic language of all biologic science

a)

true

b)

false

c)

both true and false

d)

neither true nor false

5.
Compared with the resting state, vigorously contracting skeletal muscle shows:
a)
An increased conversion of pyruvate to lactate
b)
Decreased oxidation of pyruvate to CO2 and water.
c)
A decreased NADH/NAD+ ratio.
d)
Decreased levels of fructose 2,6-bisphosphate
6.

During strenuous exercise, the NADH formed in the glyceraldehyde-3-phosphate dehydrogenase reaction in skeletal muscle must be re-oxidized to NAD+ if glycolysis is to continue. The most important reaction involved in the re-oxidation of NADH is:

a)

Fructose-1,6-bisphosphate to Dihydroxyacetone phosphate

b)

Dihydroxyacetone phosphate to glycerol-3-phosphate

c)

Glucose-6-phosphate to fructose-6-phosphate

d)

Pyruvate to lactate

7.
During the conversion of glucose to pyruvate, two NADH molecules are generated. Which of the following steps generates NADH?
a)
Conversion of glyceraldehy-3-phosphate to 1,3-bisphosphoglycerate
b)
Conversion of fructose-6-phosphate to fructose-1,6-bisphosphate
c)
Conversion of 3-phosphoglycerate to 2-phosphoglycerate
d)
Conversion of phosphoenol pyruvate to pyruvate
8.

Enantiomers are ?

a)

mirror images.

b)

non-mirror images.

c)

different in d/l carbon location.

d)

same carbon , same number of oxygen.

9.
Glucokinase is expressed primarily in...
a)
The tissues
b)
The skin cells
c)
The brain cells
d)
The liver and in the pancreatic cells
10.
Glycolysis occurs in ___________
a)
Cytoplasm
b)
Mitochondria
c)
Nucleus
d)
Ribosome
11.

The anaerobic conversion of 1 mol of glucose to 2 mol of lactate by fermentation is accompanied by a net gain of:

a)

1 ATP

b)

1 NADH

c)

2 ATP

d)

2 NADH

12.
How is alanine made?
a)
From pyruvate
b)
From the release of adesonine triphosphate
c)
from amino acids
d)
from the process in cytoplasm
13.

The conversion of 1mol of fructose-1,6-bisphosphate to 2mol of pyruvate by the glycolytic pathway results in a net formation of:

a)

1 NAD+ AND 2 ATP

b)

1 NADH AND 1 ATP

c)

2 NADH AND 2 ATP

d)

2 NADH AND 4 ATP

14.
How many ATPs will be produced in glycolysis?
a)
1
b)
2
c)
3
d)
4
15.

How many NADH formation are there in Krebs Cycle?

a)

6

b)

4

c)

3

d)

2

16.
In glycolysis, a six-carbon glucose molecule is split in half to form ____ molecules of pyruvic acid.
a)
2
b)
3
c)
4
d)
5
17.
In Glycolysis, what happens after the process of 2-phosphoglycerate?
a)
Removal of CO2 to form PEP
b)
Isomerization then forming PEP
c)
Removal of H2O to form PEP
d)
Energy Harvesting then forming PEP
18.
In Glycolysis, What kind of process will G6P (Glucose 6-Phosphate) undergo to turn into F6P (Fructose 6-Phosphate)?
a)
ATP investment
b)
Isomerization
c)
Glycogenesis
d)
ATP harvest
19.
It breaks down glucose into two molecules of pyruvate that occurs in the cytoplasm
a)
Glycolysis
b)
ATP
c)
gluconeogenesis
d)
Gatorade
20.
it is activated by phosphofructokinase.
a)
Pyruvate Kinase
b)
Glucokinase
c)
Hexokinase
d)
Isomerase
21.
It provide ‚Immediate Energy, for cells.
a)
Protein
b)
Fats
c)
Carbohydrates
d)
Nucleic Acid
22.

Oxidation followed by phosphorylation produces two NADH molecules and two molecules of BPG, each with one high-energy nitrate bond.

a)

True.

b)

False.

c)

Both True and False

d)

Neither True nor False

23.
Pyruvate is converted to ___ that provides a substrate for gluconeogenesis that replenishes the citric acid cycle intermediates
a)
Pyruvate decarboxylase
b)
Oxaloacetate
c)
Ethanol
d)
Acetyl coA
24.

Pyruvic acid is called_________.

a)

energy

b)

enzyme

c)

protein carrier

d)

metabolic intermediate

25.
The energy payoff phase occurs after glucose is split into how many carbon sugars?
a)
One.
b)
Two.
c)
Three.
d)
Four.
26.
The major biomolecular energy source in the absence of oxygen
a)
Sucrose
b)
Fructose
c)
Glucose
d)
Di ako chin-ose
27.

The process of glycolysis needs L-Glucose

a)

true

b)

false

c)

both true and false

d)

neither true nor false

28.
The reaction catalyzed by phosphofructokinase 1:
a)
Is activated by high concentrations of ATP and citrate.
b)
Uses fructose 1-phosphate as substrate.
c)
Is the rate-limiting reaction of the glycolytic pathway
d)
Is inhibited by fructose 2,6-bisphosphate
29.
The sum of all chemical changes occurring in the cell, tissue, or the body.
a)
Cellular Respiration
b)
Catabolic
c)
Metabolism
d)
Gluconeogenesis
30.
This glycolysis process happens in the absence of oxygen and allows production of ATP for tissues that lack mitochondria or cells deprived of oxygen.
a)
Aerobic
b)
Anaerobic
c)
Kreb's Cycle
d)
ETC
31.
This is where glycolysis takes place.
a)
Ketone
b)
Cytosol of the cell
c)
Mitochondria
d)
Cytoplasm
32.
Through glycolysis, the 'high energy' intermediate molecules of _____ and _____ are synthesised.
a)
ATP and NADH
b)
Acetyl and Lactate
c)
ATP and ADP
d)
ATP and NAD
33.
What does Acetyl CoA turn into after glycolysis?
a)
ATP, ADH, NADH
b)
ATP, CO2, DHAP
c)
ATP, CO2, H2O
d)
ATP, CO2, PYRUVATE
34.
What does ATP mean?
a)
Adenosine Triphosphate
b)
Adenosine Tetraphosphate
c)
Aldehyde Triphosphate
d)
Ayaw ku na siz
35.
What does ETC mean?
a)
Electron Transport Chain
b)
Electric Transportation Chain
c)
Electron Transportation Channel
d)
Ewan ko na lang if di mo pa alam sagot bes
36.
What enzyme is responsible in the 9th reaction of glycolysis?
a)
hexokinase
b)
aldolase
c)
enolase
d)
glyceraldehyde
37.
What enzyme plays an important role in the production of ATP?
a)
Aldolase
b)
Phosphofructokinase
c)
Hexokinase
d)
phosphoglycerate kinase
38.
What happens after 2-phosphoglycerate?
a)
It loses a molecule of water and becomes phosphoenolpyruvate (PEP)
b)
It gains a molecule of water and becomes phosphoenolpyruvate (PEP)
c)
It loses a molecule of water and becomes phosphoglyceratepyruvate (PEP)
d)
It gains a molecule of water and becomes phosphoglyceratepyruvate (PEP)
39.

What is ATP?

a)

Stands for adesonine triphosphate It is the primary source of energy in cells

b)

Stands for adrenaline triphosphate It is the primary source of energy in cells

c)

Stands for adenosine triphosphate It is the primary source of energy in cells

d)

Stands for aldosterone triphosphate It is the primary source of energy in cells

40.
What is catabolic?
a)
Sum of all the chemical changes occurring in the body
b)
Provide "immediate energy"
c)
Degradative; Break down complex molecules
d)
All of the above
41.
What is the enzyme of Glucose-6-Phosphate?
a)
phosphofructokinase
b)
glyceraldehydes-3-phosphate dehydrogenase
c)
enolase
d)
hexokinase
42.
What is the meaning of G3P
a)
Glutamate -3-phosphate
b)
Glyceraldehyde-3-phosphate
c)
Glyceraldehyde-3-potassium
d)
Guanine-3-phosphate
43.
What is the most important enzyme which is the control point for the glycolysis to continue?
a)
Phosphofructokinase
b)
Hexokinase
c)
Phosphoglyceratekinase
d)
Glyceraldehyde phosphate dehydrogenase
44.
What is the net ATP yield of glycolysis?
a)
1 ATP
b)
4 ATP
c)
2 ATP
d)
4 ATP
45.

what is the power house of the cell

a)

mitochondria

b)

mitochondrion

c)

nucleus

d)

Golgi apparatus

46.
What is the process by which one molecule of glucose is converted into two molecules of pyruvate, two hydrogen ions and two molecules of water?
a)
Matrix
b)
Glycolysis
c)
ETC
d)
Glycolisis
47.
What is the product of glucose and glucose?
a)
Lactose
b)
Galactose
c)
Maltose
d)
Glycogen
48.
What is the the first step in glycolysis cycle?
a)
Pyruvate
b)
Glucose-6-phosphate
c)
Fractose-6-phosphate
d)
none of the above
49.
What is the word related to enantiomer?
a)
Mirror
b)
Different formula
c)
Non comparable
d)
Deoxyribose
50.
What process happens in the matrix of the mitochondria?
a)
Glycolysis
b)
Electron Transport Chain
c)
Kreb's Cycle
d)
None of the above
51.
Where does glycolysis occur?
a)
Mitochondria
b)
Cytosol
c)
Inner Membrane
d)
Cristae
52.

Glucokinase is an isoenzyme of hexokinase which produced by which of the following?

a)

kidney

b)

muscle

c)

liver

d)

brain

53.
Where does NADH and FADH need to enter to create ATP
a)
Cristae
b)
Electron Transport Chain
c)
Liver
d)
Mitochondria
54.

Which of the following statements is not true concerning glycolysis in anaerobic muscle?

a)

Fructose-1,6-bisphosphate is one of the enzymes of the pathway

b)

It is an endergonic process

c)

It results in net synthesis of ATP

d)

It results in synthesis of NADH

55.
Which of the following can NOT be a Catabolic reaction?
a)
Carbohydrates
b)
Proteins
c)
Lipids
d)
Amino Acids
56.

Which of the following does not define glycolysis?

a)

Energy is released

b)

Occurs whether or not phosphate is present

c)

It partially oxides glucose

d)

Splitting of sugar

57.
Which of the following enzyme catalyzes the first step of glycolysis?
a)
Aldolase
b)
Pyruvate kinase
c)
Hexokinase
d)
Phosphofructokinase
58.
Which of the following molecules can be broken down into acetyl and enter the citric acid cycle?
a)
Amino acids
b)
Fatty acids
c)
Pyruvate
d)
All of the above
59.
Which of the following statements about the reactions of glycolysis is correct?
a)
In glycolysis glucose-6-phosphate is split into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate
b)
In glycolysis fructose-6-phosphate is split into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate.
c)
In glycolysis fructose-1:6-bisphosphate is split into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate
d)
In glycolysis glucose-6-phosphate is isomerized to fructose-1:6-bisphosphate.
60.
Within the inner matrix of the mitochondrion are:
a)
The enzymes of the citric acid cycle
b)
The components of the electron transport chain
c)
The enzymes of the glycolytic pathway
d)
Site for ATP synthase

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