Free Printable Ceutics - Exam 1 - Dosage Forms Miroshnyk

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Worksheets

Ceutics - Exam 1 - Dosage Forms Miroshnyk

Total questions: 43

Worksheet time: 3hrs 1mins

Name

Class

Date

1.

What are the classifications of dosage forms in the physical state

a)

solids

b)

semi-solids

c)

liquids

d)

disperse systems

e)

enteral

2.

What are the classifications of dosage forms in the intended action phase

a)

systemic

b)

local

c)

enteral

d)

parenteral

3.

What are the classifications of dosage forms in the route of administration

a)

systemic

b)

local

c)

enteral

d)

parenteral

4.

What are the classifications of dosage forms in the duration of action

a)

systemic

b)

local

c)

fast acting

d)

long acting

5.

What does the route of administration depend on

a)

drug

b)

formulation

c)

patient factors

d)

dosage

6.

How many ROA does the FDA define

a)

117

b)

118

c)

220

d)

113

7.

What are the enteral (enteros = intestine) ROA

a)

oral

b)

rectal

c)

sublingual

d)

nasal

8.

What are paraenteral (para = beside; avoiding intestinal tract) ROA

a)

intravenous/ intramuscular/ subsuteneous injections

b)

pulmonary

c)

transdermal

d)

nasal, otic, occular

e)

rectal

9.

What site of administration is involved with the oral route

a)

mouth

b)

subcutaneous, intramuscular, intradermal, intravenous

c)

mouth (inhaled)

d)

skin surface

10.

What site of administration is involved with the parenteral route

a)

mouth

b)

subcutaneous, intramuscular, intradermal, intravenous

c)

mouth (inhaled)

d)

skin surface

11.

What site of administration is involved with the pulmonary route

a)

mouth

b)

subcutaneous, intramuscular, intradermal, intravenous

c)

mouth (inhaled)

d)

skin surface

12.

What site of administration is involved with the topical route

a)

mouth

b)

subcutaneous, intramuscular, intradermal, intravenous

c)

mouth (inhaled)

d)

skin surface

13.

What site of administration is involved with the transdermal route

a)

mouth

b)

subcutaneous, intramuscular, intradermal, intravenous

c)

mouth (inhaled)

d)

skin surface

14.

What effect do drugs via the oral route have on the body?

a)

typically systemic

b)

only systemic

c)

mainly local pulmonary

d)

local

15.

What effect do drugs via the parenteral injection have on the body?

a)

typically systemic

b)

only systemic

c)

mainly local pulmonary

d)

local

16.

What effect do drugs via the pulmonary route have on the body?

a)

typically systemic

b)

only systemic

c)

mainly local pulmonary

d)

local

17.

What effect do drugs via the topical route have on the body?

a)

typically systemic

b)

only systemic

c)

mainly local pulmonary

d)

local

18.

What effect do drugs via the transdermal route have on the body?

a)

typically systemic

b)

only systemic

c)

mainly local pulmonary

d)

local

19.

What are the advantages of the oral route of administration

a)

non-invasive

b)

convenient

c)

a wide range of pH available for absorption of various drugs through GIT

d)

most natural

e)

rapid predictable absorption

20.

What are the disadvantages of the oral route of administration

a)

slow drug response

b)

chances for irregular absorption

c)

degradation of certain drugs due to stomach acid

d)

intestinal enzymes

e)

more expensive

21.

What are the dosage forms of the oral route of administration

a)

tablets/capsules

b)

elixirs

c)

solutions/syrups

d)

suspensions

e)

emulsions

22.

What are the advantages of the parenteral injection route of administration

a)

rapid predictable absorption

b)

deliver drugs that are poorly absorbed from GI/degrades in GI tract

c)

escapes first pass effect

d)

useful in infant, elderly, comatose and uncooperative patients

e)

degradation of certain drugs due to stomach acid

23.

What are the disadvantages of the parenteral injection route of administration

a)

more expensive

b)

no retrieval

c)

requires trained personnel (IV)

d)

more complex drug delivery system

24.

What are the dosage forms of the parenteral injection route of administration

a)

sterile solutions

b)

suspensions

c)

aerosols

d)

ointments

25.

What are the advantages of the pulmonary route of administration

a)

targeted delivery to bronchiolar epithelium

b)

more complex drug delivery system

c)

patients need training

d)

dose variability

26.

What are the disadvantages of the pulmonary route of administration

a)

targeted delivery to bronchiolar epithelium

b)

more complex drug delivery system

c)

patients need training

d)

dose variability

27.

What are the dosage forms of the pulmonary route of administration

a)

aerosols

b)

powders

c)

ointments

d)

creams

28.

What are the advantages of the topical route of administration

a)

convenient

b)

can be removed

c)

local action

d)

escapes first pass effect

29.

What are the disadvantages of the topical route of administration

a)

non-standardized

b)

subjective dosing

c)

expensive

d)

dose variability

30.

What are the dosage forms of the topical route of administration

a)

powders

b)

ointments

c)

pastes

d)

creams/lotions

e)

sprays

31.

What are the advantages of the transdermal route of administration

a)

convenient

b)

can be removed

c)

escapes first pass effect

d)

controlled delivery of drugs

32.

What are the disadvantages of the transdermal route of administration

a)

expensive

b)

only low mol. wt. drugs with high partition coefficient are suitable for transdermal formulations

c)

escapes first pass effect

d)

controlled delivery of drugs

33.

What are the dosage forms of the transdermal route of administration

a)

transdermal patches

b)

discs

c)

sprays

d)

creams

34.

How do drugs work

a)

API in a dosage form, ROA, drug absorption, molecular drug targets

b)

ROA, API in a dosage form, drug absorption, molecular drug targets

c)

drug absorption, ROA molecular drug targets, API

d)

API in a dosage form, drug absorption, ROA, molecular drug targets

35.

Bioavailability is the rate and extent to which a drug substance is ______ from a dosage form and becomes available at the site of drug action

a)

absorbed

b)

disposed

c)

processed

36.

Consider two dosage forms of verapamil, oral tablets and intravenous (IV) injections. How would you predict bioavailability of these two dosage forms?

a)

Equal

b)

Unequal, with oral bioavailability being higher

c)

Unequal, with oral bioavailability being lower

37.

How much bioavailability would a drug given by an intravenous injection be within the body

a)

100%

b)

Variable

c)

50%

d)

90%

38.

How much bioavailability would a drug given by oral dosage forms be within the body

a)

100%

b)

Variable

c)

50%

d)

90%

39.

What is the correct order of bioavailability ranking of oral dosage forms from most to least

a)

solutions, suspensions, capsules, uncoated tablets, coated tablets

b)

solutions, suspensions, capsules, coated tablets, uncoated tablets

c)

solutions, suspensions, uncoated tablets, coated tablets, capsules

d)

solutions, suspensions, coated tablets, uncoated tablets, capsules

40.

What are some physico-chemical properties of drug

a)

solid-state form

b)

particle size

c)

pKa

d)

log P/log D

41.

What are some factors affecting bioavailability

a)

physico-chemical properties of drug

b)

pharmaceutical excipients

c)

dosage form characteristics

d)

physiologic factors and patient characteristics

42.

What dosage form characteristics affect bioavailability

a)

disintegration/dissolution rate

b)

storage conditions

c)

solid-state form

d)

particle size

43.

What physiologic factors and patient characteristics affect bioavailability

a)

gastric emptying time/intestinal transit time

b)

gastrointestinal pH

c)

other drug effects, food, fed, or fast condition

d)

fluids

e)

drug metabolism (biotransformation)

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