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CLCHEM1 Midterm Assessment 1 - Carbohydrates

Total questions: 60

Worksheet time: 31mins

Name
Class
Date
1.

Stored form of glucose is termed as:

a)

Polysaccharide

b)

Cellulose

c)

Glycogen

d)

Glucogen

2.

Classification of sugars such as ribose and deoxyribose

a)

Tetrose

b)

Pentose

c)

Hexose

d)

Aldose

3.

Glucose, fructose, and lactose are classified as _______ based on the number of carbon chains.

a)

Tetrose

b)

Pentose

c)

Hexose

d)

Aldose

4.

On what number of Carbon is the hydroxyl group located according to the stereochemistry of carbohydrates?

a)

3

b)

4

c)

5

d)

6

5.

It is formed by the interaction of two monosaccharides plus water.

a)

Disaccharide

b)

Oligosaccharide

c)

Polysaccharide

d)

None

6.

Storage form of carbohydrates in plants that can be digested by man

a)

Starch

b)

Cellulose

c)

Both

d)

Glycogen

e)

D

7.

True or False. Glucose is the principal sugar circulating in the bloodstream.

a)

True

b)

False

8.

Considered as the most important glucose consumer

a)

Muscles

b)

Bones

c)

Brain

d)

Retina

9.

Which of the following is synonymous with ptyalin?

a)

Saivary amylase

b)

Pancreatic amylase

c)

Lipase

d)

All of the digestive enzymes

10.

Glucose is absorbed via Passive Transport.

a)

True

b)

False

11.

In the large intestine, pancreatic amylase and other enzymes convert the food into simple sugars.

a)

True

b)

False

12.

Glucose should be phosphorylated to be able to enter the cell.

a)

True

b)

False

13.

Pyruvate is a 3-carbon molecule and is an intermediate product of glycolysis.

a)

True

b)

False

14.

65% of glycogen is stored in the liver.

a)

True

b)

False

15.

Glycogenesis is the conversion of glucose into glycogen for storage.

a)

True

b)

False

16.

Cortisol is produced by the adrenal cortex to stimulate gluconeogenesis and is considered as a hypoglycemic agent.

a)

True

b)

False

17.

Glucagon is secreted by the beta cells of islets of Langerhans of pancreas to increase the glucose concentration.

a)

True

b)

False

18.

It increases the cell uptake of glucose.

a)

Insulin

b)

Glucagon

c)

Somatostatin

d)

All

19.

Growth hormone is also known as somatostatin.

a)

True

b)

False

20.

Type 1 DM

a)

Insulin resistance with insulin secretory defect

b)

Juvenile onset

c)

Treated by means of diet and exercise

d)

Associated with rare cases of ketosis

21.

Type 1 DM

a)

Insulin dependent

b)

Associated with rare cases of ketosis

c)

Insulin resistance with insulin secretory defect

d)

More common DM type

22.

Type 2 DM

a)

Caused by autoantibodies against beta cells of the pancreas

b)

Accounts for <10% of DM cases

c)

Treated by means of diet and exercise

d)

Insulin dependent

23.

Type 2 DM

a)

Associated with rare cases of ketosis

b)

With absolute deficiency of insulin

c)

Caused by autoantibodies against beta cells of the pancreas

d)

Insulin dependent

24.

Type 1 DM

a)

Caused by autoantibodies against beta cells of the pancreas

b)

Partial insulin deficiency

c)

Adult onset

d)

All

25.

Renal threshold of glucose

a)

The plasma concentration of glucose at which the active transport stops

b)

160 to 180 mg/dL

c)

Both

d)

None

26.

Site of glucose reabsorption

a)

Glomerulus

b)

PCT

c)

DCT

d)

Nephron

27.

Arises when the extra-metabolic demands of the fetus put stress on the ability of the mother to produce adequate amounts of insulin for glucose utilization

a)

Type 1 DM

b)

Type 2 DM

c)

GDM

d)

Other types

28.

Enzyme added to the reaction to convert alpha D-glucose to beta D-glucose in glucose oxidase method

a)

Dehydrogenase

b)

Mutarotase

c)

Decarboxylase

d)

Isomerase

29.

Gold standard or reference method for glucose measurement

a)

Glucose oxidase

b)

Hexokinase

c)

Hagedorn-Jensen

d)

Benedict's

30.

Glucose + fructose

a)

Sucrose

b)

Lactose

c)

Maltose

d)

Galactose

31.

Converts a disaccharide to glucose and galactose

a)

Sucrase

b)

Maltase

c)

Lactase

d)

All

32.

With normal renal function, glucosuria occurs when the plasma glucose level exceeds ___ mg/dL.

a)

130

b)

160

c)

180

d)

200

33.

2 units of glucose form what sugar?

a)

Lactose

b)

Sucrose

c)

Maltose

d)

Ribose

34.

On what type of diabetes mellitus is insulinopenia or absolute insulin deficiency present?

a)

Type 1

b)

Type 2

c)

GDM

d)

All

35.

The most common congenital form of glycogen storage disease

a)

Von Gierke

b)

Pompe

c)

Cori

d)

Andersen

36.

Enzyme deficient in individuals with Von Gierke's Disease

a)

Alpha-1,4-glucosidase

b)

Glucose-6-phosphatase

c)

Phosphorylase

d)

Branching enzyme

37.

GSD with absence of branching enzyme

a)

Von Gierke

b)

Pompe

c)

Cori

d)

Andersen

38.

GSD with absence of debranching enzyme

a)

Von Gierke

b)

Pompe

c)

Cori

d)

Andersen

39.

Absence of alpha-1-4 glucosidase can lead to cardiorespiratory failure as it affects all organs. This is a characteristic of what GSD?

a)

Von Gierke

b)

Pompe

c)

Cori

d)

Andersen

40.

Occurs due to elevated insulin levels or impaired glucose production and absorption

a)

Hypoglycemia

b)

Hyperglycemia

c)

Polyphagia

d)

Polyuria

41.

Glucagon and other hyperglycemic factors are stimulated when the plasma glucose level falls at around __ to __ mg/dL.

a)

50, 55

b)

60, 65

c)

65, 70

d)

70, 75

42.

Hypoglycemic symptoms are related to the central nervous system and appear when the plasma glucose level falls at around __ to __ mg/dL.

a)

50, 55

b)

55, 60

c)

60, 65

d)

65, 70

43.

Substance released by the islet cells of Langerhans, together with insulin; can serve as a marker of Type 1 and Type 2 DM

a)

Glucagon

b)

C-Peptide

c)

Proinsulin

d)

All

44.

Screening test for serum glucose to diagnose DM

a)

FBS

b)

RBS

c)

2-hour PPBS

d)

HbA1c

45.

Monitoring test for blood glucose levels; indicated in cases of insulin shock, ketonic comatose, and emergency cases

a)

FBS

b)

RBS

c)

2-hour PPBS

d)

HbA1c

46.

In normal individuals, glucose concentration goes back to normal _ hours after a meal.

a)

1

b)

2

c)

3

d)

4

47.

Confirmatory test for serum glucose levels

a)

FBS

b)

RBS

c)

OGTT

d)

HbA1c

48.

Glucose load given in pregnant women for GTT (in grams)

a)

50

b)

75

c)

100

d)

150

49.

Glucose load given in adults for GTT (in grams)

a)

50

b)

75

c)

100

d)

150

50.

Glucose load given in children for GTT (in grams/kg body weight)

a)

1.25

b)

1.50

c)

1.75

d)

2.00

51.

Estimate of blood glucose for the past 2-3 months

a)

Glycated hemoglobin

b)

Fructosamine

c)

Glycated albumin

d)

HbA1c

52.

Estimate of blood glucose for the past 2-3 weeks

a)

Glycated hemoglobin

b)

Fructosamine

c)

Glycated albumin

d)

HbA1c

53.

True or False. RBG is a more reliable monitoring test than HbA1c.

a)

True

b)

False

54.

True or False. Column chromatography is the more preferred method for HbA1c determination.

a)

True

b)

False

55.

Estimate plasma glucose of individual with 6% of HbA1c (in mg/dL)

a)

97

b)

126

c)

154

d)

183

56.

Positive result indicates early indication of nephropathy or renal disease

a)

Creatinine

b)

Micral Test

c)

HbA1c

d)

Albumin

57.

Anticoagulant which can be used in glucose testing if analysis is to be delayed

a)

EDTA

b)

Sodium citrate

c)

Sodium fluoride

d)

Any

58.

Rate of glucose metabolism at room temperature (in mg/dL/hr)

a)

2

b)

5

c)

7

d)

10

59.

Rate of glucose metabolism at 4 degrees Celsius (in mg/dL/hr)

a)

2

b)

5

c)

7

d)

10

60.

Represents the carbohydrates in the cyclic form; more representative of the actual structure

a)

Fisher

b)

Haworth

c)

Tertiary

d)

Quaternary