Liquid dosage form provides maximum therapeutic response in a target population with easy to shallow dosage form

Liquid dosage forms are prepared by:

Water and methylene

The rate of solution depends to the particle size and extent of agitation.

Recommended alcohol limit for OTC oral products. Which of the following is correct?

Alcohol can be used as solvent and stabilizer.

FACTORS AFFECTING SOLUBILITY EXCEPT

Useful as hydroalcoholic solvent in various

pharmaceutical processes and preparations

Iodine solution uses water as solvent.

Iodine tincture uses alcoholic solution.

Clysters is/are EXCEPT

Agitation can help speed up the absorption of a liniment.

Liquor calcis is used as an astringent.

Liquor Picis Carbonis is used as systemic anti-eczematic.

Uses of rubbing alcohol EXCEPT

Glycerin aka

Which of the ff. is correct about Glycerin?

Used as preservative and stabilizer if glycerin is not available

Purified water, USP is obtained by

Purified water is used in preparations and in finished and manufactured products, except for the

preparation of parenterals and ophthalmic

products.

Ion exchange resin uses heat to sterility purposes.

Techniques to hasten dissolution EXCEPT

used to inhibit crystallization and to modify solubility

The recommended adult dose is 4L, drink 240 mL of oral colonic lavage solution every 10 minutes until 4 L is consumed.

Cherry and Orange Syrups are good vehicle for drugs requiring acid medium.

While cocoa syrup effectively masks bitter tasting drugs.

Ora-Sweet and Ora-Sweet SF are alcohol-containing vehicle for extemporaneous compounding of syrup. Raspberry Syrup is used to disguise salty or sour taste of drugs.

For syrup,15-20% of alcohol can be used as a preservative.

The following is correct about syrup EXCEPT

METHODS OF PREPARING SYRUPS EXCEPT

Elixirs are the preferred vehicle for salts because alcohol accentuates saline taste

These are medicated elixirs EXCEPT

Brandy came from grapes. Whiskey came from malt and grain.

Methods of Preparation (SPIRIT) EXCEPT

Are CLEAR, SATURATED AQUEOUS SOLUTIONS OF VOLATILE OILS or other aromatic or volatile substances

Alcoholic or hydroalcoholic solutions prepared

from vegetable materials and chemical substances

Which of the following is correct?

Liquid extracts of vegetable drugs that

contain alcohol as a solvent, preservative, or

both.

Most topical solutions and tinctures are prepared by simple solution method. Other solutions are prepared by chemical reaction.

In a subacetate solution, the ratio of aluminum oxide to acetic acid is ____, where as in the acetate solution is _____.

Calcium hydroxide topical solution a.k.a.

It is used as antiseptic nowadays

METHODS OF PREPARING SOLUTIONS (TOPICAL SOLUTION) EXCEPT

Which of the following is correct?

Mouthwash cannot be a gargles. Gargles can be a mouthwash

The following can be used as gargles EXCEPT

Pyroxillin is composed of nitric acid and sulfuric acid in cotton. Collodions are ethereal solutions

Components of glycerites EXCEPT

Collodion is an internal preparation.

Wide mouth bottle is used to store collodion.

Tolu Balsam Tincture is a non medicated tincture. It contains 20% tincture

Use of mouthwash EXCEPT

A product will not be called syrup without ____

Which is the correct pair

the most commonly used purification of water in a water refilling station

Virlix is an example of oral solution. Cloxacillin sodium is reconstituted before administered

Omega pain Killer is an

glycerin can be used as stabilizers, solvent, preservatives

Liniment should be rubbed to enhanced faster absorption.

Enema should have the label for ”Shake well before use”.

Use as sore throat pain, sore mouth pain, and minor mouth irritation

Iso-alcoholic elixir is mixing of low alcoholic elixir and high alcoholic elixir. The primary solvent of elixir is alcohol and water.

A “For External Use” label should be affixed to;

I. Bentonite Magma

II. Calamine Lotion

III. Cod Liver Oil Emulsion

Flexible Collodion, USP contains these following ingredients:

Salicylic acid collodion, USP contains the following ingredients:

Which of the ff. is correct?

Contains clove oil and mixtures of phenol

with camphor or creosote

HLB value needed for an water-in-oil type of emulsion:

If water is the internal phase, then the emulsion is referred to as;

Which is true in o/w emulsion

Which is not a suspension

Liquified gas propellant used in aerosol products

Drugs or combination of drugs that by virtue of their high vapor pressure can be carried by an air current to the nasal passages where they exert their effect.

rank which dissolves fast: tablet, suspension, capsule, solution

Magnesium aluminum silicate is also known as;

the dispersed phase is referred to as:

Course dispersions

Coarse dispersions describes suspensions and emulsions. It range from 0.5 um to 50 um

TRUE FOR SUSPENSION EXCEPT

rate of settling of particles is dependent on EXCEPT

the larger the particles size the faster it will settle at the bottom

lotions are prepared by trituration and simple solution method

Kaolin mixture is used as anti-helmintics

microemulsion are thermodynamically stable. it means that separation will happen very slowly

macroemulsion

Bottle method are _____ method

Flavorant can only be synthetic

ALCOHOL CONTENT OF ELIXIR FOR TRADITIONAL

Majority of suspension in the market are antibiotics.

The more viscous is the medium, the more it will settle to the bottom

Particle size reduction is accomplished by:

the smaller particle size is better, to reduce scratching of cornea and irritation from eyes

Barium Sulfate for Suspension may be employed orally or rectally for diagnostic visualization of the GIT.

Dilution Test (If freely mixes with water)

conducts electric current

the process in which two or more droplet "stick" together to form an aggregates

the process in which two or more droplets merge together to form a single large droplets

Most hydrophilic colloids are anionic except methylcellulose (cationic) and chitosan (neutral)

Natural hydrophilic colloids that can be used internally and externally

The following are example of suspending agents (inorganic salts) EXCEPT

Lotions have lower viscosity than creams and gels.

The following is correct EXCEPT

Are semisolid systems consisting of either suspensions made up of small inorganic particles or large organic molecules enclosed and interpenetrated by a liquid

Inorganic gels has two-phase systems. Organic gels has three phase systems.

taking up a certain amount of

liquid without a measurable increase in

volume

taking up of a liquid by a gel with an increase in volume

the dispersion medium is squeezed out in droplets upon standing, and the gel shrinks

formed when liquid is removed from gel and only framework remains

A dispersion in which the dispersed phase is composed of small globules of liquid distributed throughout another liquid, in which it is immiscible.

used for most pharmaceutical aerosol

drugs for asthma except

Holds the gasket in placed and return the valve to closed position when pressure is released

form w/o emulsion but rarely used as they darken the preparation

Example of colloidal clays EXCEPT

The use of surfactants result in the lowering of interfacial tension between two immiscible liquids.

In dye solubility test, if the dye is dissolve and

uniformly diffuse it is ____

Disadvantages of Aerosol EXCEPT

Fever–producing organic substances arising from microbial contamination of a parenteral

product.

intrasynovial

In emergencies, IV administration of a drug may be lifesaving because of the placement of the drug directly into the circulation and the prompt action

less rapid but generally longer lasting than

those obtained from IV administration

Insulin is usually injected through ____

injection of 0.1ml for diagnostic

Example of "for injectable suspension"

Fixed vegetable oils EXCEPT

Packaged in single-dose containers of type I or type II glass that do not exceed the capacity of 1 liter

Injection that contains Sodium Chloride, Potassium Chloride, Calcium Chloride

Consideration in compounding parenterals EXCEPT

METHODS OF STERILIZATION

odd one out

Pyrogen test except

Less effective than steam sterilization.

Single-dose package includes:

SMALL VOLUME PARENTERALS EXCEPT

allowed to flow into the peritoneal cavity, used to remove toxic substances normally excreted by the kidney

Bioogical products are administered parenterally but some are given orally

Administered orally

Most ophthalmic products cannot be sterilized by heat due to active principles or polymers used to increase viscosity are not stable to heat

isotonicity limits of an ophthalmic solution in terms of

sodium chloride or its osmotic equivalent may range

from ____ without marked discomfort to the eye.

Purpose of viscosity for ophthalmic prep.

Ophthalmic solutions’ optimal viscosity is ____ centipoles.

Which one is correct for nasal spray?

Vehicle is used in hospital with oxygen. If oxygen is used alone, it is very dry.

Instrument used for inhalation therapy EXCEPT

For the treatment of ear infections, inflammation, or pain EXCEPT

For otic meds, cotton swabs placed in the ear before administration of drops will prevent excess medication from dripping out of the ear

In parenteral prep., once a drug is administered it cannot be retrieved

LIQUIFIED GAS EXCEPT

Takes place when the internal phase has a lesser density than the external phase