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WorksheetsExam 3
Total questions: 58
Worksheet time: 13mins
Name
Class
Date
1.
Which is NOT a type of artificial cloning?
a)
Reproductive
b)
Therapeutic
c)
Molecular
d)
Twinning
2.
Animals can be cloned by fusing an entire somatic cell with an enucleated egg cell.
a)
true
b)
false
3.
Embryos created by SCNT will have the same mitochondrial DNA as the somatic cell donor.
a)
true
b)
false
4.
Embryos created by SCNT will have the same mitochondrial DNA as the oocyte (egg) donor.
a)
true
b)
false
5.
Dolly the sheep was the first animal clone.
a)
true
b)
false
6.
Dolly the sheep was the first mammal cloned from an adult's cell.
a)
true
b)
false
7.
Cloned animals always look identical to each other.
a)
true
b)
false
8.
The goal of therapeutic cloning is to produce embryonic stem cells.
a)
true
b)
false
9.
Following SCNT, the embryo is fertilized in vitro.
a)
true
b)
false
10.
On which chromosome are the alleles for orange and black fur located in cats?
a)
X
b)
Y
c)
21
d)
3
11.
"Epigenetics" refers to mutations in the DNA sequence caused by environmental factors.
a)
true
b)
false
12.
Epigenetic changes include DNA methylation and histone modification.
a)
true
b)
false
13.
Epigenetic modifications can lead to changes in gene expression.
a)
true
b)
false
14.
AquAdvantage Salmon have an added gene to protect them from freezing.
a)
true
b)
false
15.
Which is NOT a way AquAdvantage Salmon are different to wild salmon?
a)
Triploid
b)
Grow year round
c)
All female
d)
Eat less each mealtime
16.
AquAdvantage Salmon are only grown in land-based facilities and not in ocean pens.
a)
true
b)
false
17.
AquAdvantage Salmon are sterile because a fertility gene was mutated.
a)
true
b)
false
18.
AquAdvantage Salmon exhibit increased feed conversion, which means they use their feed more efficiently than regular salmon.
a)
true
b)
false
19.
Antithrombin prevents excessive clotting of blood.
a)
true
b)
false
20.
Antithrombin promotes the clotting of blood.
a)
true
b)
false
21.
ATryn is the brand name of a recombinant human antithrombim
a)
true
b)
false
22.
Which of the following products did we NOT see goats making this course?
a)
ATryn
b)
Spider silk protein
c)
Ruconest
23.
Ruconest is a drug that is produced by genetically-modified rabbits in their milk
a)
true
b)
false
24.
Chinese Hamster Ovary (CHO) cells are commonly used to produce human proteins in culture.
a)
true
b)
false
25.
IVF is a pre-requisite for PGD.
a)
true
b)
false
26.
X-linked diseases typically manifest (show up) in females.
a)
true
b)
false
27.
"Aneuploid" means that part of a chromosome is attached to another.
a)
true
b)
false
28.
"Translocation" means that part of a chromosome is attached to another.
a)
true
b)
false
29.
"Aneuploid" means that there is an abnormal number of chromosomes.
a)
true
b)
false
30.
"Translocation" means that there is an abnormal number of chromosomes.
a)
true
b)
false
31.
Mosaic embryos have a mixture of genotypes.
a)
true
b)
false
32.
The CAR T-cell process involves performing gene editing on cells removed from our bodies.
a)
true
b)
false
33.
CRISPR has been used on human embryos that have gone on to become babies.
a)
true
b)
false
34.
What is Cas9?
a)
Nuclease
b)
Guide RNA
c)
Antibody
d)
Pharmaceutical
35.
All deletions in the dystrophin gene cause DMD.
a)
true
b)
false
36.
What does dystrophin NOT do?
a)
Attach to the cytoskeleton
b)
Attach to a protein in the cell membrane
c)
Support muscle fiber cells
d)
Get secreted
37.
What process is most likely to lead to a female showing DMD symptoms?
a)
Uncontrolled cell growth
b)
Exposure to radiation
c)
Exposure to mutagenic chemicals
d)
X-inactivation
38.
Exons are parts of DNA that…
a)
encode amino acids
b)
are removed during splicing
c)
are between genes
d)
promote secretion of protein products
39.
Introns are parts of DNA that…
a)
encode amino acids
b)
are removed during splicing
c)
are between genes
d)
promote secretion of protein products
40.
Exon-skipping molecular masks work on the…
a)
pre-mRNA
b)
DNA
c)
proteins
d)
mature mRNA
41.
Exon skipping by molecular masks does NOT…
a)
restore the reading frame
b)
shorten the resulting protein
c)
change the DNA
d)
affect RNA splicing
42.
Mini- and Micro-dystrophin bind to both the cytoskeleton and a protein in the cell membrane.
a)
true
b)
false
43.
CRISPR methods cannot be used to cause exon skipping.
a)
true
b)
false
44.
Frameshift mutations change the sequence of proteins but not their length.
a)
true
b)
false
45.
Monoclonal antibodies are NOT…
a)
used to treat some cancers
b)
used to detect some pregnancies
c)
made by hybridomas
d)
able to be replicated inside a patient
46.
Herceptin is a…
a)
monoclonal antibody
b)
CAR T-cell therapy
c)
oncolytic virus
d)
dystrophin replacement
47.
T-VEC is a…
a)
monoclonal antibody
b)
CAR T-cell therapy
c)
oncolytic virus
d)
dystrophin replacement
48.
Each hyridoma cell makes only one kind of mAb
a)
true
b)
false
49.
Chimeric antigen receptors are using in…
a)
monoclonal antibodies
b)
CAR T-cell therapy
c)
oncolytic viruses
d)
dystrophin replacement
50.
Chimeric antigen receptors…
a)
Only bind to antigen
b)
Activate antibody production
c)
Bind to antigen AND activate T-cell functions
d)
Bind to antigen AND activate antibody production
51.
Autologous T cells are from…
a)
the patient's body
b)
a healthy donor's body
52.
Genetically-modified oncolytic viruses do NOT…
a)
infect cancer cells
b)
trigger release of tumor antigens
c)
stimulate the immune system to target 'cold' tumors
d)
have a systemic effect
53.
Due to climate change, plants are able to grow closer to the poles than they used to
a)
true
b)
false
54.
Cabbage, Kale, and Broccoli are closely-related vegetables
a)
true
b)
false
55.
Seed shattering was selected for in plant domestication
a)
true
b)
false
56.
Plant breeders want a uniform population of plants to use in cross-breeding
a)
true
b)
false
57.
Some hybrids are more robust than either of their parents
a)
true
b)
false
58.
Glyphosate is NOT…
a)
Roundup ingredient
b)
Non-selective
c)
Engineered into plants
d)
Herbicide
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