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AP Bio Chp 20 Biotechnology

Total questions: 63

Worksheet time: 57mins

Name
Class
Date
1.

Which of the following is used to cut DNA from organisms?

a)

Gel Electrophoresis

b)

Restriction Enzymes

c)

Karyotypes

d)

Haplotypes

2.

A DNA molecule produced by combining DNA from different sources is called?

a)

Mutant DNA

b)

Polyploid DNA

c)

Diploid DNA

d)

Recombinant DNA

3.

A genetically engineered organism that contains a new gene from a different organism is called?

a)

Bacterial

b)

Genetic

c)

Transgenic

d)

Multigenic

4.
What was the first cloned animal?
a)
Dolly the Sheep
b)
Robby the Rat
c)
Milton the Mouse
d)
Beth the Goat
5.

Two llamas are produced with the exact same DNA in a science lab. What is this known as?

a)

Stem Cell Therapy

b)

Genetically Modified Organisms

c)

Cloning

d)

Gene Therapy

6.

What is gene therapy?

a)

Inserting copies of a healthy gene directly into cells with a mutated gene

b)

Producing organisms with identical copies of DNA

c)

Crossing two individuals that have similar desirable characteristics or traits

d)

Crossing two individuals that have different characteristics or traits

7.

When genes from one organism are inserted into the genes of another organism that is know as...

a)

Stem Cell Therapy

b)

Genetic Engineering

c)

Cloning

d)

Selective Breeding

8.

If scientists engineer the DNA of tomatoes to make them survive in cold temperatures, what do type of technology do those tomatoes become?

a)

Human Genome Project

b)

Genetically Modified Organisms

c)

Punnett Squares

d)

Gene Therapy

9.

Which type of cell can become any type of cells? (also known as a "blank" cell)

a)

Adult stem cells

b)

Ovum cell

c)

Embryonic stem cells

d)

Heart cell

10.

What are the two types of stem cells?

a)

Adult cells and somatic cells

b)

Embryonic cells and brain cells

c)

Adult cells and embryonic cells

d)

Embryonic cells and teens cells

11.

Mammoths pictured here are an extinct relative of the current elephants that are known today. Mammoth DNA has been discovered frozen in time with little breakdown of the DNA sequence. Recently scientists have been able to use gene sequencing to piece together fragments of extinct mammoth DNA and elephant DNA. Their work will be used to create a complete sequence of DNA that could be used in the cloning of a mammoth. In order to complete this task, researchers would need to insert the DNA into an embryo and place that embryo inside an Asian elephant in order to grow and develop. What would be an ethical concern associated with using an endangered Asian elephant to grow the embryo containing the cloned mammoth DNA?

a)

Cloning is a technology that is too new to be used in action without further research on the topic.

b)

The introduction of a new mammoth species would increase biodiversity for the already declining elephant population.

c)

Using gene sequencing to alter the DNA of an extinct organism could produce a new species of elephant completely different from the mammoth.

d)

Since the Asian elephant is already at risk for extinction, using this elephant to grow a mammoth instead of its own species could further lead to the decrease in the Asian elephant population.

12.

In the United States, there has been relatively little experimentation involving the insertion of genes from other species into human DNA. What is one reason for the limitations of these experiments?

a)

The subunits of human DNA are different from the DNA subunits of other species.

b)

Inserting foreign DNA into human DNA would require using completely new techniques.

c)

Human DNA always promotes human survival, so there is no need to insert foreign genes into it.

d)

There are many ethical questions to be answered before inserting foreign genes into human DNA.

13.

A farmer is considering the advantages of cloning a herd of cattle from a single cow. What is one advantage of a cloned herd?

a)

All cattle in the herd would have the most desired traits.

b)

All cattle in the herd would have more genetic variation.

c)

All cattle in the herd would have more resistance to diseases.

d)

All cattle in the herd would have much longer life spans.

14.

Scientists have produced a genetically modified orange tree that is resistant to disease. Which of the following is the best example of a potential benefit to society that could result from this biotechnology?

a)

reduction in orange crops produced

b)

increase in orange crops produced

c)

increase in the cost of orange crop

d)

a change in the distribution of insects that pollinate orange flowers

15.

Animal pharming is becoming more popular as the demand for human proteins and vaccines continues to grow. Animal pharming is the process of using transgenic animals to produce human drugs such as insulin and human growth hormone. Transgenic animals are animals which have been genetically transformed by splicing and inserting foreign genes into their chromosomes. If successful, the inserted gene can enable an animal to make certain proteins in its milk, blood, sperm, or eggs. Which of the following is NOT true about transgenic animals?

a)

Transgene DNA may insert itself into the genome in a way that disrupts the animal’s normal gene function.

b)

Transgenic animals cannot pass their ability to produce the desired drug to its offspring.

c)

Transgenic animals can produce the desired drug at high levels without endangering its own health.

d)

Transgenic animals can be easily tested for the new gene.

16.

What prevents scientists from cloning humans despite the fact that other mammals such as sheep have been cloned?

a)

Cloning humans would take too much time to reproduce.

b)

There are many ethical problems involved in cloning humans.

c)

The technology to clone humans has not been explored.

d)

Human reproduction is very different from that of other mammals.

17.
An application of using DNA technology to help environmental scientists would be ___.
a)
use PCR to analyze DNA at a crime scene
b)
create a tobacco plant that glows in the dark
c)
clone the gene for human growth hormone to treat pituitary dwarfism
d)
make transgenic bacteria that can be used to clean up oil spills more quickly than do the natural bacteria
18.
Recombinant DNA are currently used to produce____.
a)
clothing dye, cheese, and laundry products
b)
human antibiotics and vaccines
c)
crops that taste better and stay fresh longer
d)
all of these
19.
A gene gun and a virus may both be classified as ____ because they are mechanisms by which foreign DNA may be transferred into a host cell.
a)
bacteria
b)
plasmids
c)
vectors
d)
splicers
20.
A ____ is a small ring of DNA found in a bacterial cell.
a)
virus
b)
plasmid
c)
gene bullet
d)
PCR
21.
The entire collection of genes within human cells is referred to as the ______.
a)
human genome
b)
karyotype
c)
pedigree
d)
gene map
22.
____ is an application of the human genome project that involves the insertion of normal genes into cells with defective genes in order to correct genetic disorders.
a)
gene gun
b)
gene mapping
c)
gene linkage
d)
gene therapy
23.
Which information was most important to the development of genetic engineering techniques?
a)
the observation of nondominant alleles
b)
the discovery of lethal genes
c)
the formulation of Punnett squares
d)
the structure of the DNA molecule
24.
Researchers have been working on cloning animals such as sheep. Which result is most likely to be a negative result such as cloning?
a)
development of extra organs
b)
premature death
c)
a low rate of genetic diseases
d)
delayed aging
25.

Which best describes a controversial issue associated with the use of genetically modified crops?

a)

the use of genetically modified crops to increase potential yield

b)

the short term use of genetically modified crops in famine stricken countries

c)

the development of genetically modified crops which are resistant to herbicides

d)

the long term effects which may arise from the use of genetically modified crops

26.

What happens after the DNA from the sample is applied to the DNA microarray?

a)

the mRNA falls off the spot

b)

the DNA comes apart

c)

the tRNA will join the complementary strand

d)

the cDNA will hybridize with the single stranded DNA molecules on the microarray

27.

In the microarray, what does the RED color indicate?

a)

these genes are not expressed or turned off

b)

these genes are expressed or turned on in cancer

c)

these genes are expressed in healthy cells

d)

there are no genes in this cell

28.

What does the GREEN color indicate in DNA microarray?

a)

these genes are expressed in cancer

b)

these genes are not expressed in cancer

c)

these genes are not expressed in healthy cells

d)

there are no genes in these cells

29.

What does the YELLOW color indicate in DNA microarray?

a)

this gene is expressed in cancer cells only

b)

this gene is expressed in healthy cells only

c)

there are no genes in the cell

d)

this gene is expressed in both cancer and healthy cells

30.

From microarray data, what can we conclude?

a)

genes that cause cancer

b)

which genes may be affected in cancer

c)

genes that stop cancer

d)

which cells have genes

31.

What does BLACK indicate in dna microarray?

a)

gene expression in cancer cells

b)

gene expression in healthy and cancer cells

c)

no gene expression

d)

gene expression in healthy cells

32.

Gene regulation is the process of doing what?

a)

producing proteins

b)

replicating DNA

c)

producing RNA

d)

determining which genes will be turned on or off

33.

True or False: One example of gene regulation is when the cells from the breast do not produce insulin the way that the cells from the pancreas do.

a)

True

b)

False

34.

True or False. Every body cell in your body contains the exact same chromosomes.

a)

True

b)

False

35.

An oncogene is a gene that

a)

produces proteins that slow cell division

b)

is over-expressed in cancer

c)

repairs errors in DNA

d)

is normally present and active in all cells

36.

A proto oncogene is

a)

a gene that codes for a protein

b)

a gene that initiates and regulates the production of RNA for genes

c)

a hole that is poked into the bacterial cell membrane

d)

a normal gene that controls cell growth

37.

Tumor suppressor genes

a)

slow down the rate of cell death

b)

control the rate of cell division and cell death

c)

produce factors that control aging

d)

enable cells to grow out of control

38.

Oligonucleotide microarray can be used to detect and identify multiple viruses in a single sample.

a)

True

b)

False

39.

An electrical current is used to separate a mixture of DNA fragments from one another.

a)

Cloning

b)

gene sequencing

c)

restriction map

d)

gel electrophoresis

40.

Enzymes that cut DNA molecules when they identify specific nucleotide sequences.

a)

gel electophoresis

b)

plasmid

c)

restriction enzymes

d)

cloning

41.

These show the length of DNA fragments between restriction sites in a strand of DNA.

a)

restriction maps

b)

cloning

c)

gene sequencing

d)

bioinformatics

42.

A technique that produces millions or even billions of copies of a specific DNA sequence in just a few hours.

a)

gene sequencing

b)

PCR

c)

DNA microarray

d)

cloning

43.

A representation of parts of an individual's DNA that can be used to identify a person at the molecular level.

a)

transgenic

b)

gene sequencing

c)

genomics

d)

DNA fingerprinting

44.

The changing of an organism's DNA to give the organism new traits.

a)

recombinant DNA

b)

genomics

c)

bioinformatics

d)

genetic engineering

45.

The biological role of restriction enzymes in bacteria is to

a)

repair DNA

b)

induce DNA crossover

c)

cleave foreign DNA.

d)

All

46.

The short DNA fragments that are placed onto a microarray are called _____.

a)

Probes

b)

marker

c)

m RNA

d)

Test sequences

47.

DNA Microarray is also called as

a)

DNA Chip

b)

RNA Chip

c)

Protein Chip

d)

None

48.

CRISPR can edit DNA. What organisms naturally has CRISPR?

a)

Viruses

b)

Humans

c)

Plants

d)

Bacteria

49.

Why do bacteria have CRISPR? Check all that apply.

a)

To be able to remember which viruses they have been infected with

b)

To be able to edit virus DNA

c)

To cut apart virus DNA thereby stopping the virus infection

d)

To be able to edit their own DNA

50.

How does the guide RNA help the cell know where to cut the DNA?

a)

Guide RNA helps to find the PAM

b)

Guide RNA is complementary to the DNA sequence

c)

Guide RNA always binds to the same sequence of DNA

d)

Like restriction sites, they are always palindromes

51.

What is the role of the guide RNA?

a)

It helps the cell repair the DNA

b)

ensures that the Cas9 enzyme cuts at the right point in the genome

c)

Recognizes PAM sequences and opens up the DNA

d)

makes a cut across both strands of the DNA

52.

What does the cas9 protein do?

a)

Prevents viruses from entering bacteria

b)

Cut RNA

c)

Cut DNA

d)

Binds to RNA

53.

CRISPR-Cas9 is a type of ________ system found in bacteria.

a)

digestive

b)

endocrine

c)

circulatory

d)

immune

54.

Scientists have adapted it to turn it into a biotechnology tool for _______ DNA.

a)

building

b)

editing

c)

destroying

d)

synthesizing

55.

The enzyme portion of this complex is called ________.

a)

CRISPR

b)

Replicase

c)

Lysozyme

d)

Cas9

56.

What type of RNA is used as a GPS of sorts, to find or locate specific genes?

a)

mRNA

b)

gRNA

c)

tRNA

d)

rRNA

57.

What is PAM?

a)

a 3 letter sequence for binding on the target DNA

b)

the main gene portion of the DNA

c)

the cut site for Cas9

d)

a 10 letter sequence for binding on the target DNA

58.
Which factor can affect the epigenome?
a)
nutrition
b)
exercise
c)
stress 
d)
all of these factors can affect the epigenome
59.

Putting the gene for bioluminescence into a fish is an example of...

a)

Genetic Engineering

b)

Mutagens

c)

Environmental impact on genetics

d)

Gene Mutation

60.
Activation or deactivation of genes by environmental experiences throughout development
a)
turn on genes
b)
gene expression
c)
environmental factors
d)
gene markers
61.

1. Epigenetics is most concerned with

a)

changes in a person’s genotype resulting from environmental influences.

b)

the expression of a particular gene as influenced by external inputs.

c)

environmental influences on gene expression over experiential influences.

d)

the heritability of genotypes that have been altered over multiple generations.

62.

Which of the following best describes how genes can be regulated in the body?

a)

Genes are regulated through mutations that occur.

b)

External and Internal factors can affect which genes a cell expresses.

c)

Genes can only be regulated by changing the DNA sequence.

d)

None of these

63.
How does CRISPR differ from previous techniques of gene editing?
a)
slower, more expensive, but more accurate
b)
faster, cheaper, and more accurate
c)
faster, more expensive, more accurate
d)
slower, cheaper, less accurate