DC Conversion >>> NSR and Anticoagulants are needed for A-Fluttler. What type of effect does A-Flutter have on ventricles?

I am an NRTI; inhibit HIV replication; act as substrates for reverse transcriptase.

AE: lactic acidosis, hepatic steatosis (fatty liver) r/t motochondrial toxicity, risk of MI; hypersensitivity.

Testing for HLA-B*5701; monitor CV/LA; practice safe sex

I delay the absorption of carbs; reduce postprandial hyperglycemia; inhibit alpha glucosidase.

AE: liver dysfunction > long-term; anemia d/t Fe absorption.

Monitor liver and s/s hepatic injury.

Suffering from digoxin toxicity but don't want the expensive tx? I decrease absorption in GI.

If you have hyperglycemia, it could be DKA or HHS. Which one would it be if you had a BG = 720 with no significant ketone production or acidosis?

I inhibit replication. My topical method treats HSV; PO I can treat HSV & VZV. IV would be used for immunocompromised pts. AE: phlebitis; nephro/neuro toxic (confusion, hallucinations, etc).

Potential for viral resistance. Monitor renal/fluid/neuro. Tx decreases s/s of genitalis.

Pts need avoid sex. RN use finger cot/gloves w/ topical.

I am an IM adenovirus vector vaccine to prevent C-19. I act as a recombinant, replication-incompetent adenovirus vector.

AE: hypersensitivity, inj site swelling, fatigue, myalgia, nausea, thrombosis w/ thrombocytopenia, and Guillain-Barre Syndrome.

CDC advises mRNA over adenovirus vectors; Pt ed include duration of protention, time btw doses, prep to maximum doses/vial, follow storage precautions, treat site soreness w/ OTC analgesics, monitor pt 15 mins post-adm

When the immune system attacks/damages nerves causing weakness/paralysis, what am I?

What is the normal K range?

BBs and CCBs are similar. Both end up doing what to the heart?

As far as emetic response, activation takes place in the _?

If successful, SVT converts to NSR. I decrease electrical activity in the SA Node, slow conduction through AV, and decrease HR.

AE: SInus bradycardia, dyspnea (bronchoconstriction)

Short HL (1.5-10 secs); IV close to the heart. Pt must be on telemetry; EKG

I am a DRI; bind with renin (reduce influence of RAAS). I am a tx for HTN.

AE: diarrhea, low risk for hyperkalemia, angioedma, and cough. Risk of fetal injury.

Monitor I/O, v/s, weight, electrolytes if on multiple HTN meds.

I am a 5-HT3 receptor antagonist; tx for IBS-D in women only.

AE: Well tolerated to death; constipation, impaction, obstruction, perforation, ischemic colitis.

FDA-RM; Stop meds if not controlled in 4 wks

I am used as tx for fatal ventricular dysrhythmias. I widen QRS, prolong PR/QT intervals.

AE: Multiple risks w/ severe organ toxicitiies; Phototoxicity (bluish-gray skin)

Grapefruit juice increases levels of several meds (digoxin, warfarin, -statins)

I am a polyene antibiotic that binds to fungal cell membranes to increase permeability w/ leakage. I am a broad spectrum fungal, the DOC for most systemic mycoses like ringworms, thrush, and candidiasis.

AE: Infusion reactions, dysrhythmias, nephrotoxic, neurotoxic (damage/degeneration), hypokalemia

Minimize infusion reactions w/ meds (antipyretics, antihistamines, antiemetics, corticosterroids). Monitor v/s every 15 mins; Monitor EKG/CMP/I&O/Renal; Combo tx w/ Flucytosine>>>Crytococcal Meningitis

You have peptic ulcer disease and are taking other meds, considering the use of OTC antacids, what should pts be aware of?

Flecainide is very slow and lidocaine, a local anasthetic, is very fast. This last one, a sodium channel blocker, has immediate results. What am I?

Going with empiric therapy for an infection, after collecting the culture, what abx would be used prior to having the results?

I am an antiemetic - substance P/Nuerokinin 1 antagonist. I am a monotx for post-op NV; Combo tx for CINV.

AE: fatigue, dizziness, diarrhea, hepatic injury

There is prolonged duration of action for acute/delayed CINV; may need higher doses of warfarin and PO: contraceptives

What is the alternative name for unstable atherosclerosis?

Which form of atherosclerosis has coronary spasm?

I am a macrolide abx; bacteriostatic. I am a first alternative to PCN if allergy is present. I am a first line for pertussis, diphteria, chlamydia, respiratory/GI/GU/SSTI infections.

AE: GI; Prolonged QT; Hepatotoxicity; Ototoxicity (CNVIII); Numerous med interactions

PO: Empty stomach maximizes absorption; eat if upset stomach. Avoid w/ pts w/ QT prolongation. Monitor EKG. Increases HL of theophylline/warfarin.

I weaken bacterial cell wall through inhibition of transpeptidases. I treat infections caused by gram + (strep, enterococcus, staph). There may be cross allergies to cephalosporins.

RNs must assess history of allergies. Monitor CBC, v/s, infection s/s. C-Diff possible.

Combo tx w/ lactobacillus

I am a stimulant laxative. I treat opioid-related constipation.

AE: Suppositories may cause burning sensation.

Don't chew tablets; high abuse potential. Take no sooner than 1 hr of eating milk/antacids.

I am an mRNA C-19 vaccine. You can take me 2+1 or 3+1 for immunocompromised pts. Traditional vaccine reations; lypadenopathy within 24-48/hrs.

Muse use purple in 6 hrs; grey in 12 hrs.

Treat injection site pain with OTC analgesics.

What BP medications would you recommend to an African-American patient?

I am a SGLT2 (sodium glucose) inhibitor for TII diabetics. I block reabsorption of filtered glucose leading to glucosuria.

AE: GU Fungal infections, UTI, postural hypotension, dizziness (geriatric pts), and (very rare) lower limb amputation.

Educate about GU infections, fall precautions for pts w/ diuretics, and monitor for pain, soreness, sores, ulcers, and infections of the lower legs.

Ceftriaxone is a cephalosporin that is used because it can cross the BBB to treat bacterial meningitis. What generation cephalosporin is it?

I am used for mild/moderate cases of malaria caused by P. Vivax and P. Falciparum. I am also used as a prophylaxis of infections in erythrocytes (RBC).

AE: rare w/ prophylactic dosage; I can create GI upset and visual changes (blurred vision).

Monitor patients w/ hepatic disease. I will not prevent primary liver infection.

I am a FQ (fluroquinolone). I inhibit 2 enzymes needed for DNA replication and cell division. I am a broad spectrum abx for gram - and some gram + infections of respiratory, urinary, GI, bones, joints, skin, and soft tissue.

AE: There are CNS effects. The most recognizable AE is I can rupture that achilles tendon! I also prolong QT (usually concurrent w/ dysrhythmia meds). I have phototoxicity, GI effects, and C-Diff potential.

Educate about tendon, sunscreen/other protection, and seperate tx from dairy products.

I am a lincosamide abx; bacteriostatic. I am used to treat anaerobic infections outside of CNS. I am a first-line for severe group A strep/gangrene.

AE: C-Diff of various degrees; non-C-Diff diarrhea too.

Monitor stools. If >5, C-Diff potential. Excessive neuromuscular blockade can lead to respiratory paralysis if concurrent w/ NMBA (succinylcholine). Monitor I/O and hypotension if IV.

Which virus can you "get" w/ direct contact w/ bodily fluids in pts that are immunocompromised because healthy people keep it "restrained"?

I am a cyclic lipopeptide. I cause efflux of intracellular potassium that depolarizes the cell. I inhiibit synthesis of alot and cause cell death. I treat gram + infections only (MRSA/VRE); currently S. Aureas bloodstream/endocarditis.

AE: GI upset, myopathy (if on statin), hypotension/HTN

Monitor for myalgia, heart function (CK), and v/s

I am a systemic corticosteroid and an anti-inflammatory. I am used for C-19 pts requiring hospitalization. Pts are usually on mechanical ventilation/ECMO; tx for up to 10 days as mono/combo.

AE: Adrenal suppression, aptahy/depression. Pts show cushing's disease, GI upset, hyperglycemia, and infection.

Monitor labs, pt response to tx; Pt may require glycemic control post-discharge. Monitor cushing's s/s (weight gain, striae, fragile skin).

I am a positive inotropic (strengthen force) and negative dromotropic (slow rate) medication given to HF patients. I have a narrow therapeutic range of 0.5-0.8 ng/mL.

Be careful, you don't want to spend $4k/treatment should toxicity be an issue.

I am an antidote for severe digoxin toxicity. I am the expensive treatment with an onset <1 minute. What am I?

I am an opioid antidiarrheal; I decrease intestinal motility to allow more time for absorption of fluids and electrolytes.

AE: Excess creates morphine-like responses. Pts w/ IBD may develop toxic megacolon.

I am a schedule V med; prepare Naloxone/Narcan for OD.

I am a surfactant laxative; I alter stool consistency to decrease tension and facilitate water penetration.

AE: Minimal, occasional cramping, nausea, diarrhea, and a bitter taste.

Drink w/ a full glass of water.

I am a tetracycline; bacteriostatic. I inhibit transfer of RNA to mRNA. I am a broad spectrum for gram + and gram -. I am a 1st-line for rickettsial, chlamydia, brucellosis, cholera, mycoplasma pneumonia, lyme disease, anthrax, and Gastric H. Pylori.

AE: bone growth suppression, teeth discoloration in peds, alteration in normal flora, and photosensitivity.

There is decreased absorption of Ca, Fe, and Mg. Interactions w/ contraceptives (ineffective) and anticoagulants (enhance effect).

I am a cannabinoid, antiemetic. I treat CINV; appetite stimulation to prevent/reverse weight loss.

AE: marijuana-like, tachycardia, hypotension

I am currently a schedule III; low doses > stimulate appetite; high doses > prevent emesis

I am a NNRTI. I inhibit HIV replication.

AE: CNS symptoms (dizziness, insomnia, drowsiness, dreams, trouble concentrating), rash, teratogenicity.

There are numerous interactions, take meds ah (bed) - can reduce CNS effects. Educate on CNS symptoms/rash.

I am a fusion inhibitor for HIV. I block entry into CD4 I am used for infections resistant to other tx.

AE: SQ reactions, pneumonia s/s, and hypersensitivity

Educate on SQ administration - rotate sites; monitor respiratory and integumentary (skin)

I inhibit arabinosyl transferase which leads to impaired cell wall synthesis. I am a 1st-line for TB; also treat MAC.

AE: hepatoxicity, GI upset, and optic neuritis (CNII)

Educate/Monitor hepatitis, vision. Give w/ food to minimize GI upset.

I induce erythropoiesis and reticulocytes from bone marrow to the bloodstream. I am used to treat anema in pts w/ chronic renal failure, palliation of chemo-anemia, HIV pts w/ zidovudine, and pre-op for elective surgery.

AE: HTN (d/t rise in hematocit) and increased risk for MI, CVA, and HF

Don't agitate vial, monitor CV, liver, Fe, CBC, and hemoglobin (<=10-11). Monitored by FDA-RM

I am a glucagon-like Peptide-1 (GLP-1) antidiabetic given SQ. I cause same effects as endogenous incretins (slow gastric emptying, release of insulin, inhibit postprandial glucagon release, suppress appetite).

AE: NVD, increased risk of pancreatitis/renal impairment, hypersensitivity

Educate/Monitor s/s pancreatitis, rash, and allergy;

I am a histamine-2 receptor antagonist; I reduce gastric secretions into the GI. I am tx for duodenal/gastic ulcers, GERD, Zollinger-Ellison (too much gastric acid), aspiration pneumonitis, heartburn, and sour stomach.

AE: CNS related confusion/hallucinations, lethargy, and seizures.

Not needed w/ food; educate on lifestyle changes concurrent with pharmacotherapy

I stimulate production, maturation, and activation of neutrophils. I am used for myelosuppressive chemo, bone marrow transplant, and neutropenia (WBC).

AE: bone pain, leukocytosis

Don't agitate vial, monitor for pain (use OTC analgesics), d/c if ANC reaches 10k

I reduce conduction veolicity in atria, ventricles, and His-Purkinje; I delay repolarization and refractory period. I am used for severe ventricular dysrhythmias.

I am an azole. I inhibit synthesis of ergosterol by increasing membrane permeability. I am a broad spectrum antifungal for mycoses of esophaegeal, oropharyngeal, peritonela, urinary tract, vaginal, and systemic candida. I am the DOC for blastomycosis, histoplasmosis, and candidiasis.

AE: skin rash w/ possible Stephens Johnson

There are multiple drug interactions; educate/assess skin rash

I am a loop diuretic; I act in the thick segment of the ascending limb of Henle's. I block reabsorption of Na/Cl - preventing reabsorption of water. I am a tx for PE d/t heart failure; I also treat edema non-responsive to other tx and uncontrollable HTN.

AE: Decreased Na, Cl, K, and BP. Transient ototoxicity (increased by other ototoxic meds). Dehydration w/ increased risk of thrombosis/emboli. Ventricular dysrhythmia are associated w/ digoxin use

Assess/Monitor I&O, v/s, weight, hearing, and electrolytes (w/ med interaction), administer am-early pm, slow IV 10-20 mg/min; educate about K-rich foods

I inhibit replication by suppressing synthesis. I am used to prevent/treat CMV in immunocompromised pts.

AE: granulocytopenia, thrombocytopenia, and teratogenic

Monitor WBC/PLT; Pregnancy is contraindicated d/t fetus/embryo effects

I am an aminoglycoside; bactericidal. I treat gram + cocci and aerobic gram - bacilli like e. coli, klebsiella, and pseudomonas. I am reserved for serious infections.

AE: nephrotoxic, ototoxicity (CNVIII)

Monitor/assess serum peak/trough, urinary output, liver enzymes, hearing/balance. Increase fluid intake unless contraindicated

I am a protease inhibitor and NS5A inhibitor. I am a combo for Hepatitis C (1-6) with or w/o cirrhosis.

AE: nausea, fatigue, headache. There are possible reactions w/ HBV that can lead to further hepatic injury/failure

Pts must be tested for HBV and HCV prior to treatment. Monitor hepatitis, liver, and promote adherence due to long regiman for tx.

I am a carbapenem antibiotic. I have a very broad coverage (MDRO for bone, joint, SSTI, UTI, intraabdominal, and pelvic).

AE: GI, seizures, and superinfections

Combo tx prevents rapid metabolism in the kidneys; Reserve for use w/ infections not covered by other tx; seizure precaution (tx reduces valproic acid >>> seizures)

I am a protease inhibitor; the combo tx increases plasma concentration via metabolism inhibition. I am used to treat C-19.

AE: HTN, diarrhea, altered taste, and maylgia

Pt education on regimen (q2/25 days) There are numerous interactions, assess med usage/history. Risk of HIV resistance if undiagnosed/uncontrolled

I have PCN actions while inhibiting b-lactamase w/ my combo tx. I have an extended spectrum of coverage (PCN, gram -, and anaerobic: pseudomonaas, enterobacter, kiebsiella).

AE: low toxicity, allergic reactions

Same considerations as PCN; monitor IV and med compatibility

I am a sulfonylurea, oral antidiabetic to treat TII only.

AE: Hypoglycemia for pts w/ kidney/liver function; very rarely >>> SJS/TENS and CV toxicity

Educate pts on s/s for hypoglycemia. Contraindicated for pregnancy/breastfeeding. Pts must AVOID ETOH. Concurrent tx w/ BB can diminish sulfonylurea benefits

_ affects face/oropharynx and is transmitted through oral contact; _ shows up on the genitals and is transmitted through the sex.

Which are used to detect for HIV antibodies?

Select all of the elements associated with a DASH diet.

I am a vasodilator. I am tx for essential HTN, HTN crisis, and HF.

AE: reflex tachycardia, increased BV, and SLE syndrome.

Combo w/ isosorbide dinitrate for HF, combo w/ BB to reduce reflex tachycardia, combo w/ diuretic to reduce Na/H2O retention; monitor v/s and excessive hypotension

Thiazide diuretic; action in the early segment of the distal convoluted tubule. I block reabsorption of Na/Cl; a modest diuretic. I am a treatment for essential HTN; edema 2nd to HF, hepatic/renal disease.

AE: Same as loop w/o ototoxicity

Do not adminster to pts w/ low GFR; monitor I&O, v/s, weight, electrolytes; administer AM-early PM

I block viral entry, synthesis of messenger RNA/proteins, viral assembly/release. I am used to treat HCV and HBV.

AE: Flu-like s/s; neuropsychiatric (confusion, depression, mania); bone marrow suppression (w/ long-term tx)

Treat pain w/ OTC analgesic (acetaminophe); Monitor mental/CBC/hepatitis s/s/liver

I am primary tx/prophylaxis for TB; I inhibit synthesis of mycolic acid needed for mycobacterial cell walls. I am bactericidal to actively dividing bx; bacteriostatic to dormant bx.

AE: hepatotoxicity, neuropahty (may improve w/ B6), pyridoxine deficiency, optic neuritis, and hyperglycemia

Don't take w/ antacids (decrase absorption), educate s/s hepatitis, monitor liver, educate s/s peripheral neuropathy (B6), report visual changes, risk for non-adherence due to length of tx.

I (possibly) inhibit lipic/nucleic acid synthesis. I am a 1st-line for TB; used as combo for active TB.

AE: Hepatotoxicity, hyperuricemia (uric acid in urine)

Educate/Assess hepatitis s/s, monitor liver/serum uric acid levels, gout s/s; use NSAID PRN for pain

I bind K in the large intestine and get pooped out; tx for hyperkalemia.

AE: GI irritation, NV, constipation/diarrhea, hypokalemia

Assess bowel sounds, motility prior to administration, monitor EKG/electrolytes

I decrease automaticity with the heart; leads to accelerated repolarization w/ little/no effect on EKG. I am a short-term tx for ventricular dysrhythmia.

AE: CNS effects like confusion/drowsiness

I can be intradermal at 2/4%

I am an oxazolidinone abx; bacteriostatic; I block formation of initiation complex. I have very broad coverage for MDRO (VRE/MRSA), HCAP, CAP, staph/strep in skin/skin structure.

AE: HA, NVD, myelosuppression, neuropathy

Monitor CBC, I&O, w/ food decreases GI upset, monitor drug interactions.

MAO > HTN crisis; SSRI > Serotonin Syndrome

I am a nitrofuran abx; It is believed to interfere w/ bacterial carbohydrate metabolism and disrupt cell wall formation. I have broad spectrum gram + and gram - coverage. I am prophylaxis/tx for acute lower UTI.

AE: GI, pulmonary reactions, various hematologic effects

Not for upper UTI; encourage water intake; drink cranberry juice and avoid other nephrotoxic meds

I'm an ACE inhibitor while increasing levels of bradykinin. I am used to treat HTN, HF, post-MI therapy, prevention of MI, CVA, and death w/ clients who pose high risk, diabetic neuropathy.

AE: 1st-dose hypotension, cough (issue), angioedema (issue), hyperkalemia, fetal injury

Monitor BP/electrolytes, isntruct provider > cough/angioedmema, DAILY WEIGHTS

I am a protease inhibitor (needed for virion maturation which leaves virion immature and noninfectious); the combo boosts effects.

AE: Diarrhea, hyperglycemia w/ onset of diabetes, lipodystrophy, hyperlipidemia, prolonged PR/QT

Monitor EKG; less resistance as combo; stable at room temp (short); refrigerate (long-term); Educate pts on lipid/glucose control

I am benzo used as combo for CINV; I potentiate/increase effects of GABA for CNS depression, sedation, and suppression of emesis.

AE: CNS depression > respiratory, depression

Monitor neuro/respiratory; may need help with EPS due to phenothiazine

I am an ARB prescribed for HTN; I reduce risk of stroke, MI, and death for high risk CV, diabetic neuropathy, and diabetic retinopathy pts

AE: angioedema, fetal injury

ARBs are first choice if ACE cough/edema aren't tolerated; monitor BP if on multiple meds; educate/contact if angioedema

I am the only chlorine channel activator; laxative. I enhance the motility of small intestine/colon. I am a tx for IBS-C (female pts 18+).

AE: N/D, chest discomfort

Administer w/ food to reduce nausea

I'm a bulk-forming laxative similar to dietary fiber. I swell in water to form viscous solution/gel by softening fecal mass/increase bulk w/ growth from bacteria. I am a temporary tx for constipation, diverticulosis, and IBS.

AE: minimal due to minimal systemic absorption; esophageal obstruction if not with water/juice

Educate pts about proper administration

I'm an antiulcer medication that creates a gel to cover ulcers/a barrier against acid and pepsin. I treat duodenal/gastric ulcers.

AE: constipation w/ no serious side effects

Impedes absorption of some meds; don't administer meds (phenytoin, theophylline, digoxin, warfarin, and FQ) at least 2 hrs from sucralfate

In the hospital, a patient is suffering from angina pectoris. One NTG pill was taken 5 mins ago, what is the FIRST thing you should do next?

I am an osmotic diuretic. I am a prophylaxis for renal failure with hypovolemic shock/severe hypotension. I reduce intracranial/intraocular pressure.

AE: Edema w/ HF pts; fluid/electrolyte imbalances

Use filtered needles to prevent microscopic crystals; monitor changes in ICP. If urine output declines, stop immediately.

I am a K-sparing/aldosterone antagonist diuretic; I have very little urinary output as monotherapy/often combo w/ furosemide. I treat essential HTN; edema/HF

AE: hyperkalemia, endocrine effects menstruating, impotence, hirsutism (facial hair), and deepened voice

Monitor I&O, v/s, weight, electrolytes and interactions w/ ACEi, ARBs, and DRI Educate pts on K-rich diet

I am a CCR5 antagonist; against infections resistant to other tx. I block entry into CD4 by binding w/ CCR5 (needed for entry).

AE: likelihood of hepatic injury and risk for CV/MI

Educate/monitor liver, CV; CCR5 tropism must be performed prior to tx

I am an analog RNA polymerase inhibitor; tx for C-19 pts requiring hospitalization.

AE: severe bradycardia; elevated liver enzymes, HTN, prolonged prothrombin (delayed clotting)

Monitor liver, RUQ pain, renal function; if hypersensitivity d/c tx

I am an integrase strand transfer inhibitor that prevents insertion into host cells.

AE: Elevated liver enzymes, skin hypersensitivity; resistance is common.

Monitor hepatic injury, trend liver enzymes; educate pts on skin hypersensitivity (stop meds immediately)

I inhibit cell wall synthesis by binding to precursors of wall biosynthesis. I am a gram + for bone, joint, and bloodstream infections (MRSA and C-Diff).

AE: Nephrotoxic, ototoxic, Red Man Syndrome (rash on face, neck, and upper torso); VRE

PO for CDI; monitor trough levels, liver/renal; avoid concurrent w/ nephrotoxic Use appropriate hygience/cleaning w/ C-Diff Trough is achieved on 3rd dose

I am a biguanide, oral antidiabetic; first-line tx for TII and gestational diabeties. I can be mono or combo tx.

AE: GI-ND and decrease of appetite, toxicity related to lactic acidosis; decreased B12/folic acid absorption

Educate LA s/s, monitor renal impairment b/c med is excreted unchanged, stop for elective contrast CT/admission, potential weight loss vs other PO tx; B12/folic acid supplements needed

I am a thiazolidinediones that activates PPAR gamma to turn on insulin responsiveness (carb & lipid metabolism) for TII only (mono but usually combo).

AE: HF 2/2 fluid retition (especially if pre-existing), ovulation in premenopausal/risk of fractures for women, bladder cancer

Educate/monitor s/s HF, GU history, interactions w/ CYP2C8 inhibitors (atorvastatin, ketoconazole, rifampin, cimetidine)

I am a prokinetic; enhance upper GI motility by enhancing the action of acetylcholine. I am PO for diabetic gastroparesis, GERD suppression. I am IV for Post-Op NV; CINV

AE: Sedation, diarrhea (w/ high dosage); long-term tx >>> Tardive dyskinesia (epetitive, involuntary movements, such as grimacing and eye blinking)

Monitor responses to tx to limit TD (especially older pts); Assess GI function prior to administration

I am a nitroimidazole abx that interacts w/ bacterial DNA that causes strand breakage and loss of helical structure. I am a treatment for anaerobic bx infections - particularly CDI. I also have antiprotozal coverage.

AE: GI, HA, dry mouth/fatigue, neutropenia/thromocytopenia. I increase toxicities of lithium, benzos, cyclosporine, CCB, mood stabilizers, warfarin

Educate pts not to drink ETOH > disulfiram reactions; monitor med interactions r/t altered metabolism; give w/ food for GI upset

I am incorporated into viral RNA polymerase and lead to viral genome errors/replication inhibition. I am used to treat symptomatic/non-severe C-19.

AE: Not greater than placebo; animal studies suggest bone/cartilage effects; no peds usage

Pt education on regimen (q2/5days); not available commerically, currently EUA - AmericsourceBergen Capsules w/ or w/o food; don't cursh/open/break

I'm an acid-fast bacteria that resists decolorizing by dilute acid in staining. I am rod-shaped and often found in lungs due to their O2 requirements. Infections in lungs cause granulomas; other sites include bones, cerebral cortex, kidneys, liver, and GU.

What is the 1st-line for NV related to pregnancy?

I am a dihydropyridine calcium channel blocker w/ minimal activity on the heart. I'm tx for angina pectoris; HTN.

AE: Peripheral edema, flushing, headache, dizziness, reflex tachycardia

Reflex tachycardia is suppressed when in combo w/ BB (metoprolol); diuretics for peripheral edema; assess BP/HR prior to administration

I result in prolonged depolarization, repolarization, widened QRS, and prolonged QT intervals. I am DOC for malaria, SVT, A-Fib, A-Flutter, and sustained SVT.

AE: vasodilation, hypotension, diarrhea, blurry vision, bitter taste (CNIX), tinnitus (ringing in the ears)

Doubles digoxin levels

I'm a vasodilator administered for chest pain, angina pectoris. Accelerate care!!!

AE: Headache, hypotension, reflex tachycardia (d/t < BP), avoid touching/rebound NTG headache

Discontinue slowly to avoid vasospasm; avoid ETOH and other hypotensive/PDE5 (Viagara/Cialis>>>fatal hypotension/absolute contraindication) Nitro tolerance can be rapid/reversed quickly Pts should have low/no mid at least 8 hrs (at light)

I am an IV vasodilator for severe HF (fast/short-term tx). I am DOC: HTN crisis/emergencies and as tx for controlled hypotension during surgery to reduce bleeding.

AE: profound hypotension, monitor BP; cyanide poisoning w/ liver disease; thiocyanate toxicity (confusion, hallucinations, delirium, seizures)

Monitor v/s, EKG, BP, initial infusion 0.3-0.5 mcg/kg titrated slowly; NA/H2O retention; manage edema w/ furosemide

I am a PO/topical polyene abx that binds to fungal cell membranes to increase permeability. My coverage is similar to amphotericin B w/ limited toxicity used for oropharngeal candidiasis prophylaxis in pts w/ neutropenia and treatment for oral/vaginal candidiasis

GI: GI upset, rash, and urticaria (red itchy welts on skin)

Monitor PO w/ kids, can be given with lozenge/troche; educate on proper administration w/ oral suspensions

I'm a serotonin receptor antagonist; antiemetic for CINV and other uses.

AE: Headache, Diarrhea, and Prolonged QT/Torsades de Pointes (amplitude and twisting of the QRS complexes around the isoelectric line).

Monitor EKG; infuse slowly over 15 mins (30 mins if pre-chemo). I am effective mono, but extremely effective w/ dexamethasone

Got the flu? I inhibit neuraminidase to prevent viral replication and prevent newly formed viral particles from spreading. I must be given within 48 hrs.

AE: NV, hypersensitivity, and neuropsychiatric s/s (rare)

Rapid flu testing to cofnirm before diagnosis; assess vaccination history and onset of s/s, educate pts to monitor allergic reactions (on skin)

I am a proton pump inhibitor; I inhibit H, K, and ATPase to prevent generation of gastric acid. I'm tx for duodenal/gastric/GERD, Zollinger-Ellison (too much acid), aspiration pneumonitis, stress ulcer prophylaxis.

AE: minor w/ short-term tx, fractures, rebound acid hypersecretion, decrease Mg w/ long-term, and C-Diff diarrhea

Enteric coated tx - no crush, open, chew; take before meals (ac)

I am a thiazolidinediones that activates PPAR gamma to turn on insulin responsive genes responsible for carbohydrate/lipid metabolism for TII diabetes - mono/combo tx.

AE: HF 2/2 fluid retention; Ovulation in premenopausal women, increased risk of fractures, bladder cancer

Educate on s/s of HF, assess GU history, interactions w/ CYP2C8 inhibitors (atorvastatin, ketoconazole, rifampin, cimetidine)

I am an enzyme that is associated with the PCN immunities/resistance that many strong bacterias have. PCN that inhibit this are called penicillinases. Nafcillin is resistant to the same enzyme.

I decrease autonmaticity of the SA node, decreased velocity through AV node, decreased myocardial contractility, and prolonged PR Interval. I am tx for tachycardias (sinus & recurrent ventricular tachycardia).

AE: HF/AV Block, hypotension, bronchospams (pts w/ asthma/COPD); use of 2nd Gen BB b/c propanolol is contraindicated

I am a dopamine antagonist; antiemetic. I am tx for CINV; post-op NV w/ additional off-label use for pregnancy NV.

AE: respiratory depression, possible death w/ <2 yrs, altered cardiac conduction, CNS depression, EPS, local tissue injury, chemical irritation, gangrene if IV/IM

Monitor respiratory in <2 yrs; very slow IV Combo w/ codeine, high potential for abuse

I inhibit lipid/nucleic acid synthesis, a 1st-line for TB; combo tx for active TB.

AE: Heptatoxicity, hyperuricemia (uric acid in urine)

Educate/Assess: hepatitis, liver, uric acid levels; Report gout s/s treat pain PRN NSAID

I am an osmotic laxative that creates salts to draw water into intestinal contents; stool softener. I am tx for bowel prep for procedures/chronic constipation.

AE: nausea, bloating, cramping, flatulence, diarrhea, dehydration, Mg toxicity

Prevents dehydration and monitoring I&O, increase fluid intake; educate pts that bowel movement may take 2-4 days

I'm a combo, an isotonic solution that leads to no F/E imbalance. Tx includes 2-4L.

AE: nausea, bloating, abdominal discomfort

It involves contrates of heme in parasitized erythrocytes; IV therapy is DOC: severe malaria.

AE: Hypotension, acute circulatory failure

Watch for wide QRS/prolonged QT intervals. Slow IV administration; monitor EKG/BP, slow IV if noted; monitor electrolytes (K & Mg)

First new anginal in 25 yrs w/ modest affects. Lowers cardiac O2 demand; improves exercise tolerance/decreases pain; combined w/ nitrates/amlodipine

AE: Prolongs QT (ventricular dysrhythmias > torsades de pointes)

Increases BP by 15 in pts w/ renal impairments, monitor; several interaction; monitor EKG

Never monotx; only effective combo w/ interferon alfa. I increase the effect of interferon alfa.

AE: interferon alfa s/s, hemolytic anemia (RBC destroyed faster than made), fetal injury

Monitor mental, CBC, hepatitis/liver s/s, extended use of contraception due to prolonged HL

I am a rifamycin class abx; primary tx/prophylaxis for TB; used combo w/ another med due to resistance. I can treat leprosy (1/month dose) and MAC (w/ ethambutol and macrolide).

AE: Hepatoxicity, bodily fluids red-orange-brown discoloration, hematologic disorders, accelerated metabolism of contraceptives

Educate s/s for hepatitis, monitor liver/CBC, educate about discoloration, child-bearing females need contraceptives

I'm a peptide mimetic that increases PLT counts binding/activating human thrombopoietin receptors; minimizes thrombocytopenia in pts w/ myelosuppressive radiation and others w/ immune thrombocytopenia.

AE: abdominal pain, dizziness/headache, arthralgia, oropharyngeal pain, thromboembolism, progression of MDS>AML

Be careful w/ dosage calc, syringes w/ 0.01 mL graduations; monitor CBC; PLT should be >=50k

I am a DPP-4 inhibitor, oral antidiabetic for TII only, usually combo w/ metformin.

AE: Pancreatitis (fatal hemorrhagic/necrotizing)=rare, hypersensitivity (SJS/TENS), angioedema, and anaphylaxis

Educate on s/s of pancreatitis/rash/allery

I am an antiulcer tx that creaes a gel that adheres to the ulcer crater; protection for acid/pepsin. I am a tx for duodenal/gastric ulcers.

AE: constipation, no serious ones

May impede absorption of some meds; limit administration to 2 hrs from other meds like phenytoin, theophyllin, digoxin, warfarin, and FQ antibiotics (ciprofloxacin)

I'm a combo of sulfonamide/folate synthesis inhibitor; bacteriostatic. I am a broad spectrum for gram+ and gram -. I am commonly used for UTI, otitis media, bronchitis, shigellosis, and P. Jiroveci pneumonia.

AE: Sulfonamide > hypersensitivity (SJS/TENS), blood dyscrasias

AE: Trimethoprim > megaloblastic anemia, hyperkalemia, fetal damage

Monitor rash (stop immediately), cross with other sulfas, monitor CBC/CMP

I represent a lack of growth for hours after discontinuation of abx.

Starting treatment prior to having the lab results of the culture you collected.

I represent a lab measure of lowest concentration needed to prevent growth of a bx.

How would you describe the inotropic, chronotropic, dromotropic effects of digoxin?

Identify the s/s of digoxin toxicity.

Most important electrolytes associated with dysrhythmias?

The therapeutic range for digoxin is 0.5-2 ng/mL. What is the best practice dosage to reduce risk of toxicity?

Thiazide diuretics are modest diuretics and should not be given to pts w/ low GFR. What type of diuretic should be given as a 1st-line diuretics for HF. This is effective w/ low GFR.

First treatment for African-Americans dealing with HF?

I am a synthetic form of BNP, a short-term use for very severe/acute decompensated HF.

AE: V-Tach, headache, hypotension

I am a phenylalkylamine calcium channel blocker; I am a tx for angina pectoris, essential HTN, and dysrhythmias.

AE: constipation, cardiosuppression w/ bradycardia, AV block, and decreased contractility

Monitor interactions w/ other cardiac meds and grapefruit juice; asses BP/HR prior to administration With OD, use gastric lavage, activated charcoal, IVF, calcium gluconate, and trendelenburg

Got HF? I'm a RAAS inhibitor that decreases symptoms and prolongs life, what am I?

Select the correct alignment of hepatitis and method of transmission/contraction.

Select all that applies to ARBs.