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WorksheetsPharmaceutical Excipients - Dr. J
Total questions: 18
Worksheet time: 2hrs 30mins
Which of these is a Lubricant?
Acacia Mucilage
Lactose
Magnesium Stearate
MCC
Microcrystalline cellulose (MCC) is used as what type of excipient?
Diluent/Filler
Viscosity enhancer agents
Wetting agent
Disintegrating agent
Lakes are water soluble and Dyes are not water soluble
True
False
Which of these can be used as both an anti-adherent and glidant
Magnesium Stearate
Talc
Kaolin
Powdered Sugar
Corn Starch
Which of these is used as a diluent/filler
Mannitol
Sucrose
Warm gelatin solution
Polyvinylpyrrolidone (PVP)
MCC
Which of these are wetting agents?
MCC
Sodium Lauryl Sulfate
Spans
Tweens
Starches
What is the mannitol in this list used for?
Lubricant
Diluent
Binder
Sweetening Agent
Wetting agent
What is the sodium carboxymethylcellulose used for in this list?
Binder
Disintegrating Agent
Glidant
Wetting agent
Adsorbing Agent
Which of these excipients are binders?
Primojel
Methyl cellulose
Starch paste
Tragacanth Mucilage
PVP
An alcoholic solution is desirable when therapeutic agent is susceptible to hydrolysis
True
False
Which of the following inactive ingredients are required to prepare IR tablets by using the wet granulation method
FD&C Blue #1 Lake
Kaolin
Magnesium Stearate
MCC
Starch paste
Which excipients are needed to form tablets?
Diluents
Disintegrating agents
Lubricants
Coloring agent
Binders
When do you get a capping problem in a tablet?
Adding small and large granules together
High powder porosity
Putting a binding agent in the ingredients
Adding a glidant
How do you fix a mottling problem?
Slowly at low temperature and continuous stirring
Rapidly stirring and at high temperature
Placing the tablet through a sieve
Increasing the concentration of color
How do you prevent or fix a picking problem in a tablet?
Increasing the disintegrating agent
Controlling the moisture content
Adding sufficient anti-adherent
Adding less diluent
Which method would be ideal for low dose drugs?
Dry granulation
Direct compression
Wet granulation
Which tests are required by USP?
Weight variation
Tablet hardness
Drug content uniformity
Tablet disintegration
Drug dissolution test
If a drug has a high contact angle it means the drug is hydrophilic and you must add a wetting agent to lower the interfacial tension
True
False
