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1.

Using the above table calculate Percentage of Cells Dividing in a Cancerous Lung (a)

2.

Using the above table calculate Percentage of Cells at Rest in a Normal Stomach (a)

3.

Using the above table calculate Percentage of Cells Dividing in a Cancerous Ovary: (a)

4.

What type of molecule stimulates the cell to enter the cell cycle?

a)

Cyclins

b)

Cyclin-dependent kinases

c)

Cytokines and growth factors

d)

Tyrosine kinases

5.

What are the protein kinases that control the passage of a cell through the cell cycle called?

a)

Cdk activating kinases

b)

Cyclin-dependent kinases

c)

Cyclins

d)

Tyrosine kinases

6.

Cyclin dependent kinases are fully activated by which of the following

a)

binding to cyclins

b)

phosphorylation by Cdk activating protein kinase.

c)

binding to cyclin, plus phosphorylation by a Cdk activating protein kinase

d)

phosphorylation by a tyrosine kinase

7.

phosphorylation by a tyrosine kinase

a)

true

b)

false

8.

Each cyclin dependent kinase (Cdk) is activated by a specific cyclin and works at one specific checkpoint in the cell cycle. True or false?

a)

true

b)

false

9.

The enzyme aspartate carbomyltransferase (ACTase) is a key regulatory enzyme in nucleotide metabolism in bacteria. The activity of this enzyme was studied in the bacterium Helicobacter pylori, an important human pathogen. ACTase activity and the growth of H. pylori were measured at different concentrations of carbomoyl aspartate (CAA), the end product of the reaction catalysed by ACTase.

State the growth of H. pylori at a CAA concentration of 30 mmol dm^–3

(a)

10.

The enzyme aspartate carbomyltransferase (ACTase) is a key regulatory enzyme in nucleotide metabolism in bacteria. The activity of this enzyme was studied in the bacterium Helicobacter pylori, an important human pathogen. ACTase activity and the growth of H. pylori were measured at different concentrations of carbomoyl aspartate (CAA), the end product of the reaction catalysed by ACTase

Calculate the change in ACTase activity between CAA concentrations of 20 and 40 mmol dm^–3.

(a)

11.

Enzyme driven metabolic pathways can be made more efficient by

a)

Concenrating enzymes within specific cellular compartments

b)

grouping enzymes into free-floating, multienzyme complexes

c)

fixing enzymes into membranes so that they are adjacent to each other

d)

All of the above

12.

Which of the following statements about enzymes or their function is true?

a)

Enzymes do not alter the overall change in free energy for a reaction

b)

Enzymes are proteins whose 3-D form is key to their function

c)

Enzymes speed up reactions by lowering activation energy

d)

All of the above

13.

Tryprotophan synthetase of E.coli, a typical bifunctional oligomeric enzyme consists of:

a)

a protein designated A

b)

two proteins designated A and B

c)

a protein A and one subunit A

d)

a protein designated B

14.

In the enzyme catalyzed reaction shown below, what will be the effect on substances A, B, C, and D of inactivating the enzyme labeled E2?

A----(E1)----> B ----(E2)----> C ----(E3)---->

a)

A, B, C, and D will all still be produced

b)

A, B, C will still be produced, but not D

c)

A and B will still be produced, but not C or D

d)

A will still be produced, but not B, C, or D

15.

How is the enzyme COX-1 important in human health?

a)

It helps to transport carbon dioxide in the blood

b)

It is critical for the biosynthesis of DNA

c)

It is a chemical derivative of aspirin

d)

It catalyzes the production of hormones that maintain the stomach lining

16.

Label the following

(a)

17.

Label the following

(a)

18.

Label the following

(a)

19.

Label the following

(a)

20.

Label the following

(a)

21.

Label the following

(a)

22.

Label the following

(a)

23.

A polysaccharide made for storage of glucose in plants (usually in bulbs and tubers)

a)

fructose

b)

glycogen

c)

starch

d)

cellulose

24.

A polysaccharide made for storage of glucose in animals (takes place in the liver)

a)

glycogen

b)

starch

c)

cellulose

d)

lactose

25.

The polysaccharide used as a structural component in plant cell walls

a)

cellulose

b)

lactose

c)

ribose

d)

glucose

26.

All are essential fatty acids except

a)

Linoleic acid

b)

Linolenic Acid

c)

Arachidonic Acid

d)

Stearic Acid

27.

Cholesterol is a precursor of all except:

a)

Bile salts

b)

Bilirubin

c)

Steriods

d)

Vitamin D

28.

Which out of the following is a fatty acid with 16 carbon atoms and one double bond?

a)

Palmitoleic Acid

b)

Oleic Acid

c)

Erucic Acid

d)

Elaidic Acid

29.

Which out of the following is a fatty acid with 20 carbon atoms and five double bonds? (1)

a)

Timnodonic Acid

b)

Clupanodonic Acid

c)

Arachidonic Acid

d)

Nervonic Acid

30.

Which out of the followings is not a derived lipid?

a)

Ketone body

b)

PGE2

c)

Diacylglycerol

d)

Galactosyl ceramide

31.

In cells, which of the following can catalyze reactions involving hydrogen peroxide, provide cellular energy, and make proteins, in that order?

a)

Peroxisomes, mitochondria, and ribosomes

b)

Peroxisomes, mitochondria, and lysosomes

c)

Peroxisomes, mitochondria,and Golgi apparatus

d)

Lysosomes, chloroplasts, and ribosomes

e)

Smooth endoplasmic reticulum, mitochondria, and ribosomes

32.

Which of the following organelles is not matched with its corresponding function?

a)

Ribosome, protein synthesis

b)

Nucleolus, ribosome production

c)

Golgi apparatus, sugar synthesis

d)

Nucleus, DNA replication

e)

Chloroplasts, photosynthesis

33.

Cell fractionation is the most appropriate procedure for preparing ____ for study. (1)

a)

isolated cells which are normally found tightly attached to neighbouring cells

b)

cells without a functional cytoskeleton

c)

isolated organelles

d)

the basic macromolecules

e)

bone and other similar cells which are situated within a mineral framework

34.

Label A of this cell shown

(a)

35.

Label B of this cell shown

(a)

36.

Label C of this cell shown

(a)

37.

Label D of this cell shown

(a)

38.

Label E of this cell shown

(a)

39.

Label F of this cell shown

(a)

40.

Label G of this cell shown

(a)

41.

Label H of this cell shown

(a)

42.

Label I of this cell shown

(a)

43.

Label J of this cell shown

(a)

44.

Label K of this cell shown

(a)

45.

Label L of this cell shown

(a)

46.

Label M of this cell shown

(a)

47.

Label N of this cell shown

(a)

48.

Label O of this cell shown

(a)

49.

Label P of this cell shown

(a)

50.

In the chromosome structure I represents

a)

Two Identical Chromatids

b)

Centromere

c)

DNA molecule

d)

Centrosome

e)

Chromosome

51.

In the chromosome structure ii represents

a)

d arm

b)

Centromere

c)

p arm

d)

Sister

e)

k arm

52.

In the chromosome structure iii represents

a)

Helix

b)

Centromere

c)

Centriole

d)

Centrosome

e)

Chromosome

53.

In the chromosome structure I represents

a)

p arm

b)

z arm

c)

DNA molecule

d)

q arm

e)

Chromosome

54.

In the chromosome structure I represents

a)

Two Identical Chromatids

b)

Centromere

c)

DNA molecule

d)

Centrosome

e)

Chromosome

55.

In chromosome mapping, one map unit represents (

a)

the distance between one gene and the next on a chromosome.

b)

1% crossing over between two sites on a chromosome.

c)

1% of the length of the chromosome

d)

10% crossing over between two sites on a chromosome

e)

10% of the length of the chromosome

56.

Which refers to turning a chromosome segment around 180º and rejoining it to the original chromosome?

a)

inversion

b)

translocation

c)

deletion

d)

duplication

e)

monosomy

57.

Which refers to the loss of a complete chromosome?

a)

inversion

b)

translocation

c)

deletion

d)

duplication

e)

monosomy

58.

Which refers to the movement of a piece of one chromosome to another nonhomologous chromosome?

a)

inversion

b)

translocation

c)

deletion

d)

duplication

e)

monosomy

59.

Which refers to the loss of a portion of a chromosome?

a)

inversion

b)

translocation

c)

deletion

d)

duplication

e)

monosomy

60.

Which refers to the addition of an extra segment of a chromosome?

a)

inversion

b)

translocation

c)

deletion

d)

duplication

e)

monosomy

61.

Which of the above diagrams illustrates what happens during an inversion?

a)

b)

c)

d)

62.

Which diagram is illustrating a translocation?

a)

b)

c)

d)

63.

Which of the above abnormalities is the cause of Williams or Cri du chat syndrome?

a)

b)

c)

d)

64.

Which of the above abnormalities can lead to Down's syndrome?

a)

b)

c)

d)

65.

Energy is

a)

the ability to break or form chemical bonds

b)

the ability to do work

c)

the ability to change things

d)

the ability to break chemical bonds

66.

Food has _______________________________ energy

a)

stored chemical energy

b)

energy ready for cells to use

c)

stored kinetic energy

d)

high energy phosphates

67.

In photosynthesis the energy starts as ____________ energy and ends up as ______________ energy

a)

light; heat

b)

heat; light

c)

chemical; chemical

d)

light; chemical

68.

In cellular respiration the energy starts as ____________ energy and ends up as ______________ energy.

a)

light; heat

b)

heat; light

c)

chemical; chemical

d)

light; chemical

69.

Energy READY for the cells to use is most commonly stored in

a)

NADP+

b)

ATP

c)

ADP

d)

glucose

e)

NADPH

70.

Label the name of the actions indicated by the i in the below diagram

a)

Translation

b)

Scission

c)

SNARE assembly

d)

Translocation

e)

Budding

71.

Indicate which of the following statements are true about the role of vesicles in the transportation of materials. <br />True Statements :

a)

Materials are transported to the Golgi apparatus for processing

b)

Vesicles are membrane bound packages/droplets

c)

Vesicles cannot carry proteins

d)

Vesicle can be formed by pinching off/budding off a piece from a membrane

e)

Materials in vesicles are never transported to the plasma membrane

72.

Size is mostly 10-100μm

a)

Eukaryotic

b)

Prokaryotic

73.

Duration of cell cycle is short, takes 20-60 minutes to complete

a)

Eukaryotic

b)

Prokaryotic

74.

Transcription occurs in the cytoplasm

a)

Eukaryotic

b)

Prokaryotic

75.

Microtubules are present

a)

Eukaryotic

b)

Prokaryotic

76.

Plasmids are rarely found

a)

Eukaryotic

b)

Prokaryotic

77.

Mesosomes are absent

a)

Eukaryotic

b)

Prokaryotic

78.

Cytoplasm shows streaming movements

a)

Eukaryotic

b)

Prokaryotic

79.

Lysosomes are absent

a)

Eukaryotic

b)

Prokaryotic

80.

Genetic material is circular or linear

a)

Eukaryotic

b)

Prokaryotic

81.

Multicellular forms are rare

a)

Eukaryotic

b)

Prokaryotic

82.

Unlike those of prokaryotes, eukaryotic cell walls are composed of:

a)

A carbohydrate matrix cross-linked by short polypeptides

b)

Glycolipids and protein fibers

c)

Cellulose fibers embedded in a matrix

d)

Chitin

e)

Proteins and histones

83.

Which characteristic do eukaryotic and prokaryotic flagella have in common?

a)

Chemical composition

b)

Structure

c)

Location in the cell

d)

Function

e)

Source of Energy

84.

Channel/ carrier proteins membrane protein function

a)

used in cell surface reactions

b)

binding cells together

c)

communication between cells

d)

passive transport across the membrane

e)

active transport across the membrane

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Total questions: 84

Worksheet time: 42mins

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