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Unit 5 HBio Exam

Total questions: 63

Worksheet time: 35mins

Name
Class
Date
1.

Clearly describe the general structure of nucleic acids

a)

Long chainlike formation made of nucleotides (adenine, thymine, cytosine, guanine)

b)

Circular structure made up of ribosomes

c)

Single stranded DNA, square like structure

d)

Single celled organisms

2.

 One sentence that clearly illustrates the relationship between “nucleotide” and “nucleic acid”.

a)

Nucleotides are the monomer that in quantity make up nucleic acids.

b)

Nucleic acids make up nucleotides.

c)

No relationship

d)

Both are involved in cellular respiration

3.

DNA

a)

 Genetic code for living organisms like humans, plants and animals

b)

includes the bases adenine, thymine, guanine, and cytosine

c)

Double Helix structure

d)

Single stranded, contains uracil

4.

RNA

a)

genetic code for viruses

b)

uses adenine, uracil, guanine, and cytosine (NOT thymine)

c)

single stranded

d)

double stranded

5.

Distinguish between the 3’ and 5’ ends of a nucleic acid.

a)

5’ end (LEADING) is the end with a phosphate at the top of the strand, the 3’ end (LAGGING) is the side with a sugar at the top of the strand.

b)

3' end is the end with a phosphate at the top of the strand, the 5' end is the side with a sugar at the top of the strand

6.

 If 22% of an organism’s DNA contains ADENINE nucleotides, how many THYMINE nucleotides will the DNA contain?  Guanine?  Cytosine?

a)

22% THYMINE, 28% GUANUNE, 28% CYTOSINE

b)

44% THYMINE, 22% GUANINE, 20% CYTOSINE

c)

40% ADENINE, 40%THYMINE, 10% GUANINE, 10% CYTOSINE

d)

50% THYMINE

7.

what does helicase do????????!!!!!!!!!!!!!!!!!

a)

separates dna strands

b)

breaks apart hydrogen bonds holding the bases together

c)

glues okazagi fragments together

d)

primes the strand for DNA polymerase

8.

RNA primase

a)

prepares the strand by adding a RNA primer so that Polymerase can know where to start doing its job

b)

breaks apart hydrogen bonds holding bases together

c)

glues okazaki fragments together

d)

forms h2o molecules

9.

DNA Polymerase

a)

accurately adds the complementary bases from RNA onto the DNA strand (Uracil to Adenine, Guanine to Cytosine, ect.)

b)

 builds the new bases in the 3' to 5' direction on both the leading and lagging strand

c)

adds an extra codon as a buffer to keep genetic information safe during movement

d)

breaks apart DNA molecules and releases them into the concentration gradient

10.

ligase

a)

glues the new bases to the original bases as well as Okazaki fragments together to form a flawless strand. 

b)

breaks apart hydrogen bonds

c)

separates DNA strands

d)

adds deoxyribonucleic acids into carbon dioxide

11.

Given a strand of DNA and the DIRECTION replication occurs, determine which strand is the leading strand and which is the lagging strand.

a)

5’ is the leading strand and 3’ is the lagging strand. Leading strand builds 3’ to 5’ and lagging strand codes 3' to 5' but it looks like polymerase is building backwards on a lagging strand.

b)

3' to 5'

c)

5’ end (leading) is the end with a phosphate at the top of the strand, the 3’ end (lagging) is the side with a sugar at the top of the strand.

d)

ERRORX_

12.

Why is the lagging strand referred to by that name?

a)

It is called lagging strand because it builds in the opposite direction of the replication fork, also because of the okazaki fragments that cause  a delay in replication.

b)

it builds slower than the leading strand because it only builds 5' to 3' which appears to be backwards on the lagging strand

c)

because it does not code properly

13.

okazaki fragments

a)

Small segments of DNA on the lagging strand that are later glued together by ligase

b)

are a result of the lagging strand only able to build 3' to 5' and rushing to the top of the newly unwinded DNA, even if it is not finished building.

14.

why do okazaki fragments exist?

a)

 DNA unwinds and the lagging strands polyamerase can only build bases in the 5' to 3' direction. Becauseof this the polyamerase needs to keep racing up to where the DNA is being unravelled, even if it is not finished with the application of the complimentary bases necessary. In result, the lagging strand has fragments of DNA instead of one long continuous strand. The fragments created are Okazaki fragments. 

b)

the direction of photosynthesis

c)

guanine connects to cytosine

15.

what is the central dogma of biology?

a)

Chromosomes are made of DNA 

b)

Segments of DNA code for protein

c)

Protein in turn relates to a trait (eye color, enzymes, hormones, hemoglobin in blood cells, proteins in the cell membrane)

d)

A theory that genetic code flows only in one direction, from DNA to RNA to Protein or RNA directly to Protein.

e)

this beautiful creature

16.

carries the blueprint/ instructions for a specific protein. delivers these instructions in order for the protein to be built. 

a)

messenger RNA (mRNA)

b)

transfer RNA

(tRNA)

c)

ribosomal RNA

(rRNA)

d)

DNA

17.

forms part of the ribosome, is exported to the cytoplasm to help translate the instructions brought from mRNA into protein. Created of single stranded RNA.

a)

ribosomal RNA

rRNA

b)

transfer RNA

tRNA

c)

messenger RNA

mRNA

d)

DNA

18.

serves as a link/bridge between the mRNA molecule and the growing chain of amino acids that makeup protein, transfers amino acids and brings them to the ribosome.

a)

transfer RNA

tRNA

b)

messenger RNA

mRNA

c)

ribosomal rna

rRNA

d)

DNA

19.

 a type of enzyme that is responsible for forming new copies of DNA in the form of nucleic acid molecules. Replicates DNA molecules to build a new strand of DNA during DNA replication.

a)

DNA Polymerase

b)

RNA Polymerase

20.

 syntheses RNA by following a strand of DNA, copies DNA sequence and translates it into RNA language during transcription.

a)

RNA Polymerase

b)

DNA Polymerase

21.

transcription vs DNA replication

a)

Transcription is involved in replicating the DNA into RNA, while DNA replication makes another copy of DNA, not RNA

b)

Theyre the same thing

c)

DNA Replication replicates DNA into RNA and transcription makes another copy of DNA

22.

transcription

a)

comes before translation (C before L)

b)

the creation of RNA from the DNA language template where the code in the DNA is converted into a complimentary RNA code.

c)

the synthesis of a protein from an mRNA template where the code in the mRNA is converted into an amino acid sequence in a protein.

23.

translation

a)

the synthesis of a protein from an mRNA template where the code in the mRNA is converted into an amino acid sequence in a protein.

b)

comes second (C before L)

c)

the RNA that was built in transcription from the original DNA template is now being converted into an amino acid codon to code for a specific protein.

d)

the creation of RNA from the DNA language template where the code in the DNA is converted into a complementary RNA code.

24.

  a three letter base that codes for an amino acid

a)

codon

b)

anti codon

c)

hydrogen base

d)

phosphate

25.

the complimentary codon that corresponds to a given codon. For example, CGG is the _________ to GCC.

a)

anti codon

b)

codon

c)

granum

d)

golgi body

26.

consists of two separate RNA-protein complexes, known as the small and large subunits. The large subunit sits on top of the small subunit, with an RNA template sandwiched between the two. Made of both RNA and protein, is the site of protein synthesis in the cell.

a)

ribosome

b)

large vesicle

c)

nucleus

d)

nuclear envelope

27.

A chromosome is composed of long folded strands of what?

a)

DNA tightly coiled many times around proteins called histones.

b)

wheat, barley, tomato seeds

c)

carbohydrates

d)

lipids

28.

On chromosomes are many genes. Define gene.

a)

The basic unit of heredity, passed from parents to children

b)

lipids that do not work in passive transport

c)

genome

d)

found in the golgi apparatus

29.

a mutation is DNA when a single nucleotide is changed to a different base

a)

point mutation

b)

frameshift mutation

30.

the addition or deletion of one or more nucleotide bases that are not added or taken in multiples of three, throwing off the whole sequence. 

a)

frameshift mutation

b)

point mutation

31.

 the addition of one of more nucleotide bases into a sequence of nucleotides, this can be a type of frameshift mutation

a)

insertion

b)

deletion

c)

substitution

32.

 the deletion of one or more nucleotides from a strand of DNA, up to a whole strand of DNA can be lost due to this mutation.

a)

deletion

b)

insertion

c)

substitution

33.

one nucleotide base is substituted for another nucleotide base

a)

deletion

b)

insertion

c)

substitution

34.

the most problematic mutation out of the following options:

insertion

deletion

or substitution

a)

insertion

b)

deletion

c)

substitution

35.
a)

LOOK AT THIS PICTURE IMMIDIATLY

b)

NOTICE THE 5' SIDE HAS A PHOSPHATE ON TOP AND 3' SIDE HAS A SUGAR BASE ON TOP THATS HOW YOU TELL THE DIFFERENCE

36.

what is the sugar found in RNA

a)

ribose

b)

deoxyribose

c)

sugar

d)

hydrogen

37.

where does transcription take place

a)

nucleus

b)

ribosome

c)

golgi

38.

The picture below shows the steps of DNA replication beginning with step one and ending with step three.


​Because you are reusing the old, or parent, DNA strand DNA replication is said to be

a)

Semi- Conservative

b)

Semi-discontinuous

c)

Continuous

d)

Fully-Conserveative

39.

The picture below shows an enzyme unwinding and unzipping DNA.

​What is the name of this enzyme?

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

40.

Match he nucleotide with its complementary nucleotide. (DNA to DNA).


Adenine -

a)

Thymine

b)

Guanine

c)

Cytosine

41.

Match he nucleotide with its complementary nucleotide. (DNA to DNA).


Cytosine-

a)

Thymine

b)

Guanine

c)

Adenine

42.

Which is the first step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

43.

Which is the second step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

44.

Which is the third step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

45.

Which is the fourth step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

46.

Which letter in the picture below depicts the leading strand in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

47.

Which letter in the picture below depicts the lagging strand in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

48.

Which letter in the picture below depicts the replication fork in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

49.

If a person suffered from a disorder where their DNA fragments were unable to fill in the missing slots in between the fragments of the lagging strand, they would most likely have a disorder that affected which enzyme?

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

50.

DNA replication runs from ______' to _____' and is said to be ______________________

a)

5, 3, antiparallel

b)

3, 5, antiparallel

c)

5, 3, parallel

d)

3, 5, parallel

51.

The directionality of DNA is said to be ___________, because it is side by side by goes in opposite directions.

a)

Anti-directional

b)

Parallel

c)

Anti-parallel

d)

Anti-uniform

52.

Nitrogen bases are joined by which type of bond?

a)

polar bonds

b)

hydrogen bonds

c)

phosphate bonds

d)

deoxyribose bonds

53.

What is a mutation?

a)

Adenine

b)

a change/mistake in DNA

c)

a copy of the original DNA

d)

Guanine

54.

Frameshift mutations result from -

a)

additions

b)

substitutions

c)

deletions

d)

all of these

55.

Point mutations result from -

a)

none of these

b)

substitutions

c)

additions

d)

deletions

56.

in DNA what is the sugar called

a)

deoxyribose

b)

ribose

c)

sugar

d)

glyerin

57.

what is the backbone of DNA made of

a)

sugar and phosphates

b)

rna

c)

protein

d)

molecules

58.

where in EUKARYOTIC cells does DNA replication take place?

a)

nucleus

b)

golgi

c)

cytoplasm

d)

nuclear envelope

59.

where in PROKARYOTIC cells does DNA replication take place

a)

cytoplasm

b)

nucleus

c)

central vesicle

60.

where can RNA be found in a eukaryotic cell?

a)

inside the nucleus

b)

outside the nucleus

c)

the golgi

d)

chloroplast

61.

proteins are made of

a)

polypeptide chains

b)

skin

c)

molecules

d)

atoms

62.

which of the following is an example of a purine

a)

adenine and guanine

b)

adenine and thymine

c)

cytosine and guanine

63.

is this a nucleotide

a)

yes

b)

no