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WorksheetsPrinciples Of Inheritance And Variation
Total questions: 102
Worksheet time: 51mins
Genetics is the branch of biology which deals with
variation
inheritance
Both (a) and (b)
study of characters
The inheritance of characters from parents to offspring is
variation
heredity
inheritance
resemblance
The tendency of offspring to differ from their parents is called
variation
heredity
inheritance
resemblance
Mendel’s hybridisation experimental material was
Pisum sativum
Lathyrus odoratus
Oryza sativa
Mirabilis jalapa
Which one from those given below is the period of Mendel’s hybridisation experiments?
1856-1863
1840-1850
1857-1869
1870-1877
Mendel investigated characters in garden pea plant manifested in two traits which were
similar
non-zygote
identical
opposite
A true breeding line is characterised by the presence of
stable trait inheritance due to the continuous selfpollination
varying traits in different generations due to the cross pollination
single trait in all generations due to allogamy
varying trait inheritance in a single generation due to geitonogamy
How many pairs of true breeding varieties were selected by Mendel for his experiment on pea plant?
12
13
14
15
Out of 7 contrasting trait pairs selected by Mendel, how many traits were dominant and recessive?
7 and 7
8 and 6
6 and 8
5 and 9
Among the following characters, which one was not considered by Mendel in his experiments on pea?
Stem – Tall or Dwarf
Trichomes – Glandular or Non-glandular
Seed – Green or Yellow
Pod – Inflated or Constricted
Which is correct about traits choosen by Mendel for his experiment on pea plant?
Terminal pod was dominant
Constricted pod was dominant
Green coloured pod was dominant
Tall plants were recessive
What contributed to Mendel’s success?
I. Selection of pureline pea varieties.
II. Knowledge of history.
III. Selecting one character at a time.
IV. Statistical analysis and mathematicallogic.
Choose the correct option
I, II, III and IV
II and III
I, III and IV
II, III and IV
The first hybrid progeny obtained by Mendel were called
F1 -progeny
F0 -progeny
F2 -progeny
F3 -progeny
F1 -progeny of a cross between pure tall and dwarf plant is always
tall
short
intermediate
None of these
According to Mendel’s observation, which generation of progeny always represents the phenotype of the dominant parent?
F4
F2
F1
F0
The Mendel crossed true breeding tall and dwarf plant varieties in his experiment. Tallness was the dominant character and dwarfness was recessive. The recessive character appeared in
F1
F2
F3
F2 and F3
How did Mendel obtained recessive (dwarf) character in F2 -generation?
By self-pollinating F1
By self-pollinating F2
By cross-pollinating F1
By cross-pollinating F2
The proportion of plants that were dwarf and tall, respectively in F2 -generation of Mendel’s experiment was
41 th and 43 th
43 th and 41 th
32 rd and 31 rd
31 rd and 34 rd
Mendel crossed tall and dwarf plants. In F2 -generation both the tall and dwarf plants were produced. This shows
blending of characters
atavism
non-blending of characters
intermediate characters
During his experiments, Mendel used the term factor for
genes
traits
characters
qualities
Genes which codes for a pair of contrasting characters are
recessive character
dominant character
alleles
alternative gene
Choose the incorrect match.
Phenotype – Physical appearance of an organism
Genotype – Expressed genes
Homozygous – Identical alleles of a gene present at the same locus
Heterozygous – Genes of an allelic pair are not same
Number of gametes produced by a homozygous and a heterozygous individuals of genotype AA and Aa, respectively are
1 and 2
2 and 3
3 and 5
many
A cross in which parents differ in a single pair of contrasting character is called
monohybrid cross
dihybrid cross
trihybrid cross
tetrahybrid cross
The phenotypic ratio of a monohybrid cross in F2 -generation is
3 : 1
1 : 2 : 1
2 : 1 : 1
9 : 3 : 3 : 1
The genotypic ratio of a monohybrid cross in F2 -generation is
3 : 1
1 : 2 : 1
2 : 1 : 1
9 : 3 : 3 : 1
F2 -generation in a Mendelian cross showed that both genotypic and phenotypic ratios are same as 1 : 2 : 1. It represents a case of
codominance
dihybrid cross
monohybrid cross with complete dominance
monohybrid cross with incomplete dominance
If the male plant has the genotype TT and the female plant has the genotype tt then they contribute pollen and egg, respectively with
T and T gametes
tt and TT gametes
TT and tt gametes
T and t gametes
Graphical representation to calculate the probability of all possible genotype of an offspring in genetic cross is called
Bunett square
Morgan square
Punnett square
Mendel square
Test cross involves a cross between
recessive F1 -plant and dominant F2 -plant
recessive F2 -plant and dominant F3 -plant
dominant F2 -plant and recessive parent plants
dominant F2 -plant and heterozygous parent plants
Mendel performed test cross to know the
genotype of F1
genotype of F2
genotype of F3
genotype of F4
When alleles of two contrasting characters are present together and one of the character expresses itself during the cross while the other remains hidden gives the
aw of purity of gametes
law of segregation
law of dominance
law of independent assortment
The allele which expresses itself in both homozygous and heterozygous condition is called
dominant allele
recessive allele
incomplete dominant allele
split allele
3:1 ratio in F2 -generation is explained by
law of partial dominance
law of dominance
law of incomplete dominance
law of purity of gametes
The law of dominance is applicable in inheritance of
seed colour in pea
flower colour in Mirabilis jalapa
starch grain size in pea
roan coat colour in cattles
Mendel’s principle of segregation means that the germ cells always receive
one pair to alleles
one quarter of the genes
either one allele of father or one allele of mother
any pair of alleles
The law based on fact that the characters do not show any blending and both the characters are recovered as such in F2 -generation although one character was absent in F1 -progeny, is
law of purity of gametes
law of independent assortment
law of incomplete dominance
law of dominance
The types of gametes formed by the genotype RrYy are
RY, Ry, rY, ry
RY, Ry, ry, ry
Ry, Ry, Yy, ry
Rr, RR, Yy, YY
In law of independent assortment how many factors are involved (for a dihybrid cross)
1
2
3
4
In Mendel’s experiments with garden pea, round seed shape (RR) was dominant over wrinkled seeds (rr) and yellow colour (YY) was dominant over green colour (yy). What are the expected phenotypes in the F1 -generation of the cross RRYY × rryy?
Only round seeds with yellow cotyledons
Only wrinkled seeds with yellow cotyledons
Only wrinkled seeds with green cotyledons
Round seeds with yellow cotyledons and wrinkled seeds with yellow cotyledons
In cross between pure breeding pea plants having yellow round (YYRR) and green wrinkled (yyrr) seeds, find out the total seeds (plants) having yellow colour in F2 -generation.
12
10
14
11
In a cross between plants having yellow round (YYRR) and green wrinkled (yyrr) seeds, what will be the ratio between seeds having yellow and green seed colour?
3 : 2
3 : 1
9 : 7
7 : 9
Total number of round seed in the F2 -generation of a cross between plants having pure yellow round and pure green wrinkled seeds is
9
12
11
1
Ratio observed in dihybrid cross (phenotypically)
3 : 1
1 : 2 : 1
9 : 7
9 : 3 : 3 : 1
The number of different genotypes observed in the F2 -generation of a dihybrid cross are
9
12
4
6
Mendel’s result on inheritance of characters were rediscovered by
de Vries
Correns
von Tschermak
All of these
The literal meaning of chromosome is
painted body
coloured body
doubling body
thread-like body
The concept of chromosome movement during meiosis to explain Mendel’s laws was used by
Sutton and Boveri
Malthus
Correns
Morgan
The chromosomes as well as genes occur in pair and the two alleles of a gene pair are located on
homologous chromosomes
non-homologous chromosomes
single chromosome
All of the above
Who proposed the chromosomal theory of inheritance?
Sutton and Mendel
Boveri and Morgan
Morgan and Mendel
Sutton and Boveri
Experimental evidences of chromosomal theory of inheritance was given by
S Boveri
TH Morgan
de Vries
W Sutton
Morgan’s experimental organism was
Drosophila melanogaster
Mangifera indica
Mirabilis jalapa
Drosophila indica
Both chromosome and gene (Mendelian factors) whether dominant or recessive are transmitted from generation to generation in
changed form
unaltered form
altered form
disintegrated form
Choose the incorrect pairing among the following.
Sutton and Boveri – Chromosome theory
Walter and Boveri – Behaviour of chromosome during cell divisions
TH Morgan – Mutation
Henking – Barr bodies
Linked genes that were observed by Morgan were present on
X-chromosome
different chromosome
heterologous chromosome
paired chromosome
Strength of the linkage between the two genes is
proportionate to the distance between them
inversely proportionate to the distance between them
depend on the chromosomes
depend upon the size of chromosomes
In Morgan’s experiment, white and yellow genes were linked tightly, while white and miniature wing were loosely linked. The per cent recombination shown by these genes were
50% each
72% and 8.3%, respectively
0.3% and 53%, respectively
1.3% and 37.2%, respectively
In a test cross involving F1 dihybrid flies, more parental-type offspring were produced than the recombinant type offspring. This indicates
chromosomes failed to separate during meiosis
the two genes are linked and present on the same chromosome
Both of the characters are controlled by more than one gene
the genes are located on two different chromosomes
The frequency of recombination between gene pairs on the same chromosome as a measure of the distance between genes was explained by
Gregor J Mendel
Alfred Sturtevant
Sutton-Boveri
TH Morgan
What map unit (centi Morgan) is adopted in the construction of genetic maps?
A unit of distance between two expressed genes representing 100% cross over
A unit of distance between genes on chromosomes, representing 1% cross over
A unit of distance between genes on chromosomes, representing 50% cross over
A unit of distance between two expressed genes representing 10% cross over
Choose the incorrect pair with respect to sex determination in different organisms.
Grasshopper = XO type
Birds = ZZ-ZW type
Drosophila = XX-XO type
Human = XX-XY type
In XX and XY type of sex-determination
males are heterogametic
females are isogametic
Both (a) and (b)
None of the option is correct
Male heterogamety is seen in
Humans
Grasshopper
Drosophila
All of these
Choose the incorrect pair amongst the following
Male bird – Homogametic
Female bird – Heterogametic
Male Drosophila – Heterogametic
None of the above
The chromosomal denotation for heterogametic female and homogametic males are
ZW and ZZ
ZO–ZZ
XX–XO
Both (a) and (b)
The number of chromosomes in females and males honeybees are
32
16
32 and 16, respectively
16 and 32, respectively
The unfertilised eggs in honeybees develop into
males
queen
worker
Both (a) and (c)
In honeybees, male and female gametes are produced through
mitosis
mitosis and meiosis, respectively
meiosis
meiosis and mitosis, respectively
Mutation is a phenomena which results in alteration in sequences of
DNA
RNA
proteins
Both (a) and (b)
Mutation may result in
change in genotype
change in phenotype
change in metabolism
All of these
Chromosomal abberation is commonly found in the
cancer cells
normal cells
healthy cells
autosomal cells
Point mutation arises due to the change in
single base DNA
single base pair of DNA
segment of DNA
double base pair of DNA
If there are four different types of nitrogenous bases (A, T, G and C) then how many different types of transitions and transversion are possible?
Transition = 8, Transversion = 4
Transition = 4, Transversion = 4
Transition = 8, Transversion = 4
Transition = 4, Transversion = 8
Sickle-cell anaemia is a classical example of
frame-shift mutation
point mutation
Both (a) and (b)
Frame-shift mutation arises due to
deletion of base pair of DNA
insertion of base pair of DNA
Both (a) and (b)
change in single base pair of DNA
Mutagens are
chemical agents which cause change in DNA
physical agents which cause mutation
Both (a) and (b)
None of the above
Analysis of traits of several generation of a family in the form of diagram is called
gene analysis
chromosome analysis
allele analysis
pedigree analysis
Pedigree analysis is very important in human beings because
it helps genetic counselors to avoid disorders
it shows origin of traits
it shows the flow of traits in family
All of the above
Colour blindness in humans
results in defect in either red or green cone of eyes
is caused due to the mutation in gene found on X-chromosome
affects males more frequently than females
All of the above
A woman has an X-linked condition on one of her X-chromosomes. This chromosome can be inherited by
Only grand children
Only sons
Only daughters
Both (b) and (c)
A normal-visioned man whose father was colourblind, marries a woman whose father was also colourblind. They have their first child as a daughter. What are the chances that this child would be colourblind?
100%
0%
25%
50%
A man whose father was colourblind marries a woman, who had a colourblind mother and normal father. What percentage of male children of this couple will be colourblind ?
25%
0%
50%
75%
A normal woman whose father was colourblind, marries a normal man. What kinds of children can be expected and in what proportion ?
All daughters normal, 50% of sons colourblind
All daughters normal, all sons colourblind
50% daughters colourblind, all sons normal
All daughters colourblind, all sons norma
Which of the following most appropriately describes haemophilia?
X-linked recessive gene disorder
Chromosomal disorder
Dominant gene disorder
Recessive gene disorder
In haemophilia, the affected protein is a part of a cascade of protein which is involved in the
formation of RBCs
formation of WBCs and platelets
coagulation of blood
anticoagulation
In sickle-cell anaemia,
Both parents are heterozygous carriers, but are unaffected
Single pair of allele controls the disease
Only Hb Hb s s show diseased phenotype
All of the above
In individual suffering from phenylketonuria,
enzyme phenylalanine hydroxylase is absent
phenylalanine do not convert to tyrosine
phenylpyruvic acid is formed
All of the above
Thalassemia in humans
is an autosome linked recessive blood disorder
can transmit from parents to offspring when both parents are unaffected carriers (heterozygous)
caused due to the mutation or deletion of one of the α or β-globin chain
All of the above
α-thalassemia in humans is controlled by
HBA1 and HBA2 genes on chromosome 16
HBA1 gene on chromosome 12
HBA2 gene on chromosome 11
HBA1 and HBA2 genes on chromosome 9
β-thalassemia in humans is controlled by
HBA2 gene on chromosome 16
HBB gene on chromosome 11
HBA1 gene on chromosome 15
HBA1 and HBA2 gene on chromosome 8
Failure of segregation of chromatid during cell division cycle results in the gain or loss of chromosome which as called
aneuploidy
hypopolyploidy
hyperpolyploidy
polyploidy
A cell telophase stage is observed by a student in a plant brought from the field. He tells his teacher that this cell is not like other cells at telophase stage. There is no formation of cell plate and thus the cell is containing more number of chromosomes as compared to other dividing cells. This would result in
polyploidy
somaclonal variation
polyteny
aneuploidy
Non-disjunction in meiosis results in
trisomy
normal diploid
gene mutation
None of these
A disease caused by an autosomal primary non-disjunction is
Down’s syndrome
Klinefelter’s syndrome
Turner’s syndrome
Sickle-cell anaemia
Karyotype of Down’s syndrome has how many chromosomes?
43
46
47
45
I. Short statured body with small round head. II. Furrowed tongue and partially opened mouth. III. Palm is broad with characteristic palm crease. IV. Slow physical, psycomotor and mental development. These are the characters of
Down’s syndrome
Turner’s syndrome
Klinefelter’s syndrome
Edward syndrome
Choose the correct pair.
Gynacoemastia – Development of breasts
Turner’s syndrome – Loss of an X-chromosome in females
Polyploidy – Seen in plants
All of the above
What is the genetic disorder in which an individual has an overall masculine development gynaecomastia and is sterile?
Klinefelter’s syndrome
Edward syndrome
Down’s syndrome
Turner’s syndrome
Klinefelter’s syndrome results from
XX egg and Y from sperm
XX egg and XY sperm
X egg and XY sperm
Both (a) and (c)
In which genetic condition, each cell in the affected person, has three sex chromosomes XXY?
Thalassemia
Klinefelter’s syndrome
Phenylketonuria
Turner’s syndrome
Female suffering from Turner’s syndrome possess
45 + XO
rudimentary ovaries
lack of secondary sexual characters
All of the above
Which of the following are chromosomal disorders.
I. Colour blindness
II. Down’s syndrome
III. Phenylketonuria
IV. Turner’s syndrome
V. Thalassaemia
I, II and III
II, IV and V
III, IV and V
II and IV
