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HISTO CONNECTIVE TISSUE PART 1

Total questions: 66

Worksheet time: 40mins

Name
Class
Date
1.

It is a major constituent of connective tissue which consist of different combinations of protein fibers & ground substance.

a)

EXTRACELLULAR MATRIX

b)

MESENCHYME

c)

GROUND SUBSTANCES

d)

CONNECTIVE TISSUES

2.

it is a omplex anionic, hydrophilic

proteoglycans, glycosaminoglycans

(GAGs), and multiadhesive

glycoproteins

a)

EXTRACELLULAR MATRIX

b)

MESENCHYME

c)

GROUND SUBSTANCES

d)

CONNECTIVE TISSUES

3.

It is where the connective tissue originates

(a)  

4.

“Spindle-shaped” and is undifferentiated & have large nuclei

w/ prominent nucleoli & fine chromatin

(a)  

5.

2 types of connectuve tissue cells

(a)  

6.

A type of tissue cells that is relatively stable, exhibit little movement &

can be regarded as permanent resident of the tissue.

a)

Resident population cell

b)

Wandering population cell

c)

Mesenchymal cells

7.

A type of tissue cell which consist of cells that have migrated into the

tissue from the blood in response to specific stimuli.

a)

Resident population cell

b)

Wandering population cell

c)

Mesenchymal cells

8.

Example/s of wandering cell population

a)

Macrophages and WBC only

b)

Collagen and Adipocyte

c)

Collagen, Macrophages and WBC

d)

Adipocytes, Collagen, Macrophages, and WBC

9.

Fibroblast has an active nucleus

a)

TRUE

b)

FALSE

c)

MAYBE

10.

It is the most common cells in CT and produces and maintains most of the ECM

components.

a)

FIBROBLAST

b)

FIBROCLAST

c)

ADIPOCYTES

d)

MACROPHAGES

11.

2 TYPES OF FIBROBLAST

(a)  

12.

Termed as "Fibroblast"

(a)  

13.

Termed as "Fibrocyte"

(a)  

14.

What fibroblast is involved in wound healing

a)

Myo-fibroblast

b)

Fibrocyte

c)

Active fibroblast

d)

Multinuclear Giant Cells

15.

Smaller, spindle-shaped w/ fewer processes & much lesser RER, &

contains a darker, more heterochromatic nucleus (has prominent dark area)

a)

Myo-fibroblast

b)

Fibrocyte

c)

Active fibroblast

d)

Multinuclear Giant Cells

16.

Also known as the fat cell

(a)  

17.

Specialized for cytoplasmic storage of lipid as neutral fats

a)

adipocyte

b)

macrophages

c)

mast cells

d)

plasma cells

18.

This is where you will find the mesenchymal cells

(a)  

19.

the most abundant protein of the body

a)

COLLAGEN

b)

MAST CELLS

c)

ADIPOCYTES

d)

MICROGLIA

20.

When adipocytes accumulate in large numbers, they are called (a)  

21.

Well-developed phagocytic ability and specialize in turnover of protein fibers

and removal of dead cells, tissue debris, or other particulate material

a)

MACROPHAGES AND THE MONONUCLEAR

PHAGOCYTE SYSTEM

b)

MONONUCLEAR

PHAGOCYTE SYSTEM

c)

CONNECTIVE TISSUE CELL SYSTEM

d)

ADIPOSE CELL SYSTEM

22.

Cell that is found in the connective tissue

a)

HISTIOCYTE

b)

KUPFFER CELL

c)

MICROGLIA

d)

OSTEOCLAST

23.

Cell that is found in the liver

a)

HISTIOCYTE

b)

KUPFFER CELL

c)

MICROGLIA

d)

OSTEOCLAST

24.

Cell that is found in the nervous tissue

a)

HISTIOCYTE

b)

KUPFFER CELL

c)

MICROGLIA

d)

OSTEOCLAST

25.

Cell that is found in the bone

a)

HISTIOCYTE

b)

KUPFFER CELL

c)

MICROGLIA

d)

OSTEOCLAST

26.

Cell that is found in the lungs

a)

HISTIOCYTE

b)

ALVEOLAR MACROPHAGE

c)

MICROGLIA

d)

LANGERHAN'S CELL

27.

Cell that is found in the epidermis

a)

HISTIOCYTE

b)

ALVEOLAR MACROPHAGE

c)

MICROGLIA

d)

LANGERHANS' CELL

28.

Cell that is found in the epididymis lymph nodes

a)

HISTIOCYTE

b)

ALVEOLAR MACROPHAGE

c)

DENDRIC CELL

d)

LANGERHANS' CELL

29.

When macrophages are stimulated, they change their morphologic characteristics and properties, becoming (a)  

30.

When adequately stimulated, macrophages may increase in size and

fuse to form (a)  

31.

They usually form scar tissue

a)

Multinuclear giant cells

b)

Macrophages

c)

Plasma cells

d)

Mast cells

32.

ablity of a cell to change the color of a basic dye

(a)  

33.

Characterized by a very basophilic cytoplasm, dotted with a lot of

basophilic secretory granules

a)

Multinuclear giant cells

b)

Macrophages

c)

Plasma cells

d)

Mast cells

34.

sulfated GAG that acts locally as an anticoagulant

a)

Heparin

b)

Histamine

c)

Phospholipid

d)

Serine Proteases

35.

Promotes increased vascular permeability and smooth musclecontraction

a)

Heparin

b)

Histamine

c)

Phospholipid

d)

Serine Proteases

36.

Activate various mediators of inflammation

a)

Heparin

b)

Histamine

c)

Phospholipid

d)

Serine Proteases

37.

Numerous near small blood vessels in skin and mesenteries

a)

Perivascular mast cells

b)

Mucosal mast cells

c)

Vascular mast cells

d)

B-lymphocyte

38.

Lines digestive and respiratory tracts

a)

Perivascular mast cells

b)

Mucosal mast cells

c)

Vascular mast cells

d)

B-lymphocyte

39.

(a)   is/are the last differential stage of the B-lymphocyte

40.

B-lymphocyte-derived, antibody producing cells

a)

Multinuclear giant cells

b)

Macrophages

c)

Plasma cells

d)

Mast cells

41.

plasma cells are normally found in the peripheral blood as well as in tissues

a)

TRUE

b)

FALSE

c)

SOMETIMES

42.

Blood by migrating between the endothelial cells lining the venules to

enter connective tissue by a process called _____

a)

Diapedesis

b)

Chemotaxis

c)

Cytokines

d)

Serine proteases

43.

phenomenon by which specific cell types are attracted by

specific molecules, draws much larger numbers of leukocytes into inflamed

tissues.

a)

Diapedesis

b)

Chemotaxis

c)

Cytokines

d)

Serine proteases

44.

most abundant collagen/s. It forms large eosinophil bundles known as collagen fibers.

a)

COLLAGEN TYPE I

b)

FIBRILLAR COLLAGENS

c)

TRANSMEMBRANE COLLAGENS

d)

MULTIPLEXINS

45.

Transmembrane collagen found in focal adhesions

a)

COLLAGEN TYPE XIII

b)

COLLAGEN TYPE XVII

c)

COLLAGEN TYPE XVIII

d)

COLLAGEN TYPE XXV

46.

Transmembrane collagen found w/in the hemidesmosomes

a)

COLLAGEN TYPE XIII

b)

COLLAGEN TYPE XVII

c)

COLLAGEN TYPE XVIII

d)

COLLAGEN TYPE XXV

47.

Transmembrane collagen found in metastatic cancer cells

a)

COLLAGEN TYPE XIII

b)

COLLAGEN TYPE XVII

c)

COLLAGEN TYPE XVIII

d)

COLLAGEN TYPE XXV

48.

Transmembrane collagen found in brain-specific collagen

a)

COLLAGEN TYPE XIII

b)

COLLAGEN TYPE XVII

c)

COLLAGEN TYPE XVIII

d)

COLLAGEN TYPE XXV

49.

responsible for collagen suprastructure in the basement membrane of epithelial cells.

a)

TYPE IV

b)

TYPE VI

c)

TYPE VII

d)

TYPE VIII

50.

forms beaded filaments

a)

TYPE IV

b)

TYPE VI

c)

TYPE VII

d)

TYPE VIII

51.

forms anchoring fibrils that attach the basement membrane to the ECM.

a)

TYPE IV

b)

TYPE VI

c)

TYPE VII

d)

TYPE VIII

52.

Provide supporting framework for the cellular constituents of various tissues and organs.

a)

RETICULAR FIBERS

b)

ELASTIC FIBERS

c)

EXTRACELLULAR MATRIX

d)

COLLAGEN FIBERS

53.

Allow tissues to respond to stretch and distension.

a)

RETICULAR FIBERS

b)

ELASTIC FIBERS

c)

EXTRACELLULAR MATRIX

d)

COLLAGEN FIBERS

54.

mutation on fibrillins genes causing the blood vessels to swell because of the lack of resistance in elastic fibers; thus, causing aneurysm.

a)

Marphan syndrome

b)

Microscopic polyangiitis

c)

Lupus

d)

Schnitzler Syndrome

55.

Most abundant heteropolysaccharide components of ground substance.

a)

Glycosaminoglycans

b)

Proteoglycans

c)

Multiadhesive glycoproteins

d)

Collagen

56.

Composed of core protein to which are covalently attached various numbers and

combinations of the sulfated GAGs.

a)

Glycosaminoglycans

b)

Proteoglycans

c)

Multiadhesive glycoproteins

d)

Collagen

57.

Largest, almost unique, and most ubiquitous (everywhere) GAG.

a)

Glycosaminoglycans

b)

Proteoglycans

c)

Multiadhesive glycoproteins

d)

Hyaluronic acid

58.

Type of protoglycan that binds fibrils of type I collagen

a)

Decorin

b)

Syndecan

c)

Aggrecan

d)

Laminin

59.

Type of protoglycan that serve as additional attachments of the cell to the ECM.

a)

Decorin

b)

Syndecan

c)

Aggrecan

d)

Laminin

60.

Type of protoglycan that has a core protein bearing many chondroitin sulfate

and keratin sulfate chains.

a)

Decorin

b)

Syndecan

c)

Aggrecan

d)

Laminin

61.

Most abundant glycoprotein in CT

a)

FIBRONECTIN

b)

LAMININ

c)

TENASCIN

d)

OSTEOPONTIN

62.

Present in basal and external laminae.

a)

FIBRONECTIN

b)

LAMININ

c)

TENASCIN

d)

OSTEOPONTIN

63.

Appears during embryogenesis

a)

FIBRONECTIN

b)

LAMININ

c)

TENASCIN

d)

OSTEOPONTIN

64.

Present in the ECM of bone and has an important role in sequestering

calcium and promoting calcification of the ECM.

a)

FIBRONECTIN

b)

LAMININ

c)

TENASCIN

d)

OSTEOPONTIN

65.

Caused by the pumping action of the heart, which forces water out across the capillary wall

a)

Hydrostatic pressure

b)

Colloid osmotic pressure

c)

Absolute pressure

d)

Stagnation pressure

66.

produced by plasma proteins such as albumin, which draws water back into the capillaries.

a)

Hydrostatic pressure

b)

Colloid osmotic pressure

c)

Absolute pressure

d)

Stagnation pressure