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WorksheetsHISTO CONNECTIVE TISSUE PART 1
Total questions: 66
Worksheet time: 40mins
It is a major constituent of connective tissue which consist of different combinations of protein fibers & ground substance.
EXTRACELLULAR MATRIX
MESENCHYME
GROUND SUBSTANCES
CONNECTIVE TISSUES
it is a omplex anionic, hydrophilic
proteoglycans, glycosaminoglycans
(GAGs), and multiadhesive
glycoproteins
EXTRACELLULAR MATRIX
MESENCHYME
GROUND SUBSTANCES
CONNECTIVE TISSUES
It is where the connective tissue originates
(a)
“Spindle-shaped” and is undifferentiated & have large nuclei
w/ prominent nucleoli & fine chromatin
(a)
2 types of connectuve tissue cells
(a)
A type of tissue cells that is relatively stable, exhibit little movement &
can be regarded as permanent resident of the tissue.
Resident population cell
Wandering population cell
Mesenchymal cells
A type of tissue cell which consist of cells that have migrated into the
tissue from the blood in response to specific stimuli.
Resident population cell
Wandering population cell
Mesenchymal cells
Example/s of wandering cell population
Macrophages and WBC only
Collagen and Adipocyte
Collagen, Macrophages and WBC
Adipocytes, Collagen, Macrophages, and WBC
Fibroblast has an active nucleus
TRUE
FALSE
MAYBE
It is the most common cells in CT and produces and maintains most of the ECM
components.
FIBROBLAST
FIBROCLAST
ADIPOCYTES
MACROPHAGES
2 TYPES OF FIBROBLAST
(a)
Termed as "Fibroblast"
(a)
Termed as "Fibrocyte"
(a)
What fibroblast is involved in wound healing
Myo-fibroblast
Fibrocyte
Active fibroblast
Multinuclear Giant Cells
Smaller, spindle-shaped w/ fewer processes & much lesser RER, &
contains a darker, more heterochromatic nucleus (has prominent dark area)
Myo-fibroblast
Fibrocyte
Active fibroblast
Multinuclear Giant Cells
Also known as the fat cell
(a)
Specialized for cytoplasmic storage of lipid as neutral fats
adipocyte
macrophages
mast cells
plasma cells
This is where you will find the mesenchymal cells
(a)
the most abundant protein of the body
COLLAGEN
MAST CELLS
ADIPOCYTES
MICROGLIA
When adipocytes accumulate in large numbers, they are called (a)
Well-developed phagocytic ability and specialize in turnover of protein fibers
and removal of dead cells, tissue debris, or other particulate material
MACROPHAGES AND THE MONONUCLEAR
PHAGOCYTE SYSTEM
MONONUCLEAR
PHAGOCYTE SYSTEM
CONNECTIVE TISSUE CELL SYSTEM
ADIPOSE CELL SYSTEM
Cell that is found in the connective tissue
HISTIOCYTE
KUPFFER CELL
MICROGLIA
OSTEOCLAST
Cell that is found in the liver
HISTIOCYTE
KUPFFER CELL
MICROGLIA
OSTEOCLAST
Cell that is found in the nervous tissue
HISTIOCYTE
KUPFFER CELL
MICROGLIA
OSTEOCLAST
Cell that is found in the bone
HISTIOCYTE
KUPFFER CELL
MICROGLIA
OSTEOCLAST
Cell that is found in the lungs
HISTIOCYTE
ALVEOLAR MACROPHAGE
MICROGLIA
LANGERHAN'S CELL
Cell that is found in the epidermis
HISTIOCYTE
ALVEOLAR MACROPHAGE
MICROGLIA
LANGERHANS' CELL
Cell that is found in the epididymis lymph nodes
HISTIOCYTE
ALVEOLAR MACROPHAGE
DENDRIC CELL
LANGERHANS' CELL
When macrophages are stimulated, they change their morphologic characteristics and properties, becoming (a)
When adequately stimulated, macrophages may increase in size and
fuse to form (a)
They usually form scar tissue
Multinuclear giant cells
Macrophages
Plasma cells
Mast cells
ablity of a cell to change the color of a basic dye
(a)
Characterized by a very basophilic cytoplasm, dotted with a lot of
basophilic secretory granules
Multinuclear giant cells
Macrophages
Plasma cells
Mast cells
sulfated GAG that acts locally as an anticoagulant
Heparin
Histamine
Phospholipid
Serine Proteases
Promotes increased vascular permeability and smooth musclecontraction
Heparin
Histamine
Phospholipid
Serine Proteases
Activate various mediators of inflammation
Heparin
Histamine
Phospholipid
Serine Proteases
Numerous near small blood vessels in skin and mesenteries
Perivascular mast cells
Mucosal mast cells
Vascular mast cells
B-lymphocyte
Lines digestive and respiratory tracts
Perivascular mast cells
Mucosal mast cells
Vascular mast cells
B-lymphocyte
(a) is/are the last differential stage of the B-lymphocyte
B-lymphocyte-derived, antibody producing cells
Multinuclear giant cells
Macrophages
Plasma cells
Mast cells
plasma cells are normally found in the peripheral blood as well as in tissues
TRUE
FALSE
SOMETIMES
Blood by migrating between the endothelial cells lining the venules to
enter connective tissue by a process called _____
Diapedesis
Chemotaxis
Cytokines
Serine proteases
phenomenon by which specific cell types are attracted by
specific molecules, draws much larger numbers of leukocytes into inflamed
tissues.
Diapedesis
Chemotaxis
Cytokines
Serine proteases
most abundant collagen/s. It forms large eosinophil bundles known as collagen fibers.
COLLAGEN TYPE I
FIBRILLAR COLLAGENS
TRANSMEMBRANE COLLAGENS
MULTIPLEXINS
Transmembrane collagen found in focal adhesions
COLLAGEN TYPE XIII
COLLAGEN TYPE XVII
COLLAGEN TYPE XVIII
COLLAGEN TYPE XXV
Transmembrane collagen found w/in the hemidesmosomes
COLLAGEN TYPE XIII
COLLAGEN TYPE XVII
COLLAGEN TYPE XVIII
COLLAGEN TYPE XXV
Transmembrane collagen found in metastatic cancer cells
COLLAGEN TYPE XIII
COLLAGEN TYPE XVII
COLLAGEN TYPE XVIII
COLLAGEN TYPE XXV
Transmembrane collagen found in brain-specific collagen
COLLAGEN TYPE XIII
COLLAGEN TYPE XVII
COLLAGEN TYPE XVIII
COLLAGEN TYPE XXV
responsible for collagen suprastructure in the basement membrane of epithelial cells.
TYPE IV
TYPE VI
TYPE VII
TYPE VIII
forms beaded filaments
TYPE IV
TYPE VI
TYPE VII
TYPE VIII
forms anchoring fibrils that attach the basement membrane to the ECM.
TYPE IV
TYPE VI
TYPE VII
TYPE VIII
Provide supporting framework for the cellular constituents of various tissues and organs.
RETICULAR FIBERS
ELASTIC FIBERS
EXTRACELLULAR MATRIX
COLLAGEN FIBERS
Allow tissues to respond to stretch and distension.
RETICULAR FIBERS
ELASTIC FIBERS
EXTRACELLULAR MATRIX
COLLAGEN FIBERS
mutation on fibrillins genes causing the blood vessels to swell because of the lack of resistance in elastic fibers; thus, causing aneurysm.
Marphan syndrome
Microscopic polyangiitis
Lupus
Schnitzler Syndrome
Most abundant heteropolysaccharide components of ground substance.
Glycosaminoglycans
Proteoglycans
Multiadhesive glycoproteins
Collagen
Composed of core protein to which are covalently attached various numbers and
combinations of the sulfated GAGs.
Glycosaminoglycans
Proteoglycans
Multiadhesive glycoproteins
Collagen
Largest, almost unique, and most ubiquitous (everywhere) GAG.
Glycosaminoglycans
Proteoglycans
Multiadhesive glycoproteins
Hyaluronic acid
Type of protoglycan that binds fibrils of type I collagen
Decorin
Syndecan
Aggrecan
Laminin
Type of protoglycan that serve as additional attachments of the cell to the ECM.
Decorin
Syndecan
Aggrecan
Laminin
Type of protoglycan that has a core protein bearing many chondroitin sulfate
and keratin sulfate chains.
Decorin
Syndecan
Aggrecan
Laminin
Most abundant glycoprotein in CT
FIBRONECTIN
LAMININ
TENASCIN
OSTEOPONTIN
Present in basal and external laminae.
FIBRONECTIN
LAMININ
TENASCIN
OSTEOPONTIN
Appears during embryogenesis
FIBRONECTIN
LAMININ
TENASCIN
OSTEOPONTIN
Present in the ECM of bone and has an important role in sequestering
calcium and promoting calcification of the ECM.
FIBRONECTIN
LAMININ
TENASCIN
OSTEOPONTIN
Caused by the pumping action of the heart, which forces water out across the capillary wall
Hydrostatic pressure
Colloid osmotic pressure
Absolute pressure
Stagnation pressure
produced by plasma proteins such as albumin, which draws water back into the capillaries.
Hydrostatic pressure
Colloid osmotic pressure
Absolute pressure
Stagnation pressure
