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IB-Mitotic Cycle

Total questions: 115

Worksheet time: 10hrs 35mins

Name
Class
Date
1.

Which of the following occurs latest in the cell cycle?

a)

Chromosomes move to the center of the cell.

b)

Chromosomes move to opposite ends of the cell.

c)

Microtubules begin to form.

d)

The nucleus breaks down.

2.

The mitotic spindle fibers attach to chromosomes via special structures termed _____.

a)

centrioles

b)

asters

c)

kinetochores

d)

centrosomes

3.

Which series progresses from the thinnest to the thickest in diameter?

a)

DNA > histone > chromosome > nucleosome

b)

histone > chromosome > DNA > nucleosome

c)

nucleosome > histone > DNA > chromosome

d)

DNA > histone > nucleosome > chromosome

4.

The following are the activities of cells that need to carry out before mitosis, except _____.

a)

replicate its DNA

b)

duplicate its centrosome

c)

undergo cytokinesis

d)

make sister chromatids

5.

During which stages of mitosis does a typical cell contain twice its normal number of chromosomes?


1. Prophase

2. Metaphase

3. Anaphase

4. Telophase

a)

1 and 2

b)

2 and 3

c)

3 and 4

d)

1, 2, 3 and 4

6.

A scientist stains the chromosomes of a diploid plant cell with a fluorescent dye to observe the telomeres.

This cell has 38 chromosomes.

How many telomeres will the scientist observe in one of the nuclei during telophase of mitosis?

a)

38

b)

76

c)

114

d)

152

7.

This cell is in which stage of mitosis?

a)

Early prophase

b)

Late prophase (prometaphase)

c)

Metaphase

d)

Anaphase

8.

During mitosis in animal cells, which process occurs after prophase?

a)

Centrioles move towards the poles of the cell.

b)

Centromeres attach to spindle microtubules.

c)

Chromatids join to form chromosomes.

d)

Chromosomes condense and become visible.

9.

Which events listed are part of mitosis?


1 interphase

2 prophase

3 cytokinesis

a)

1, 2 and 3

b)

1 and 2 only

c)

1 only

d)

2 only

10.

Which of the following events do NOT occur in prophase of mitosis?

a)

DNA condenses to form chromosomes

b)

nuclear membrane breaks down

c)

mitotic spindle begins to form

d)

chromosomes are replicated

11.

Which of the following occurs latest in the cell cycle?

a)

Chromosomes move to the center of the cell.

b)

Chromosomes move to opposite ends of the cell.

c)

Microtubules begin to form.

d)

The nucleus breaks down.

12.

The following are the activities of cells that need to carry out before mitosis, except _____.

a)

replicate its DNA

b)

duplicate its centrosome

c)

undergo cytokinesis

d)

make sister chromatids

13.

During which stages of mitosis does a typical cell contain twice its normal number of chromosomes?


1. Prophase

2. Metaphase

3. Anaphase

4. Telophase

a)

1 and 2

b)

2 and 3

c)

3 and 4

d)

1, 2, 3 and 4

14.

This cell is in which stage of mitosis?

a)

Early prophase

b)

Late prophase (prometaphase)

c)

Metaphase

d)

Anaphase

15.

Which events listed are part of mitosis?


1 interphase

2 prophase

3 cytokinesis

a)

1, 2 and 3

b)

1 and 2 only

c)

1 only

d)

2 only

16.

During mitosis in animal cells, which process occurs after prophase?

a)

Centrioles move towards the poles of the cell.

b)

Centromeres attach to spindle microtubules.

c)

Chromatids join to form chromosomes.

d)

Chromosomes condense and become visible.

17.
The causes of cancer may include which of the following?
a)
chemical carcinogens
b)
UV radiation
c)
inheritance
d)
all of these
18.

In the eukaryotic cell, it is the longest stage of the cell cycle and generally its function is to prepare the cell to division process.

a)

Interphase

b)

Mitotic phase

c)

Synthesis Phase

d)

All of the above

19.

Programmed cell death is known as ____________.

a)

Apoptosis

b)

Oncogene

c)

Proto-oncogene

d)

Tumor suppressor gene

20.

The monomers units of DNA and RNA are

a)

amino acids

b)

monosaccharides

c)

nucleotides

d)

fatty acids

21.

Which of the following enzymes catalyzes the linkage together of RNA nucleotides to form RNA?

a)

polymerase

b)

ligase

c)

ribozyme

d)

reverse transcriptase

22.

The RNA codon AUG means

a)

add amino acid methionine

b)

start the protein here

c)

add the amino acid tyrosine

d)

end the polypeptide chain here

23.

The transfer of genetic info from DNA to RNA is called

a)

translation

b)

transcription

c)

initiation

d)

elongation

24.

Which of the following sequences best describes the flow of information that takes place when a gene directs the synthesis of a cellular component?

a)

RNA-DNA-RNA-PROTEIN

b)

DNA-RNA-PROTEIN

c)

PROTEIN-RNA-DNA

d)

DNA-AMINO ACID-RNA-PROTEIN

25.

When RNA is being made, the RNA base ____ always pairs with the base ___ in DNA.

a)

U-T

b)

T-G

c)

U-A

d)

A-U

26.
Choose the nucleotide sequence of the RNA strand that would be complementary to the following strand: 
GTAGTCA
a)
UATUAGA
b)
ACGACTG
c)
CAUCAGU
d)
CATCAGT
27.
What amino acid is represented by the codon UUA?
a)
Phenylalanine
b)
Tyrosine
c)
Leucine
d)
Stop codon
28.
Which is the mRNA molecule that would be transcribed from this DNA template:
TGGCAAGTACGT
a)
ACCGTTCATGCA
b)
UGGCAAGUACGU
c)
UCCGUUCUUGCU
d)
ACCGUUCAUGCA
29.
How many amino acids are coded for by this sequence of nucleotides:
ATG GGA ACT CCA
a)
4
b)
2
c)
6
d)
12
30.
If a DNA molecule is 18% Guanine which of the following is correct?
a)
18% cytosine, 32% adenine, 32% thymine
b)
32% cytosine, 18% adenine, 32% thymine
c)
18% cytosine, 64% adenine, 64% thymine
d)
32% cytosine, 32% adenine, 18% thymine
31.

A nucleotide in DNA is composed of

a)

A deoxyribose sugar, a phosphate, and a nitrogen

b)

Only a deoxyribose sugar and nitrogen base

c)

Only a deoxyribose sugar and a phosphate

d)

None of the above

32.

Between the two strands of a DNA segment the nitrogen bases are held together by

a)

Covalent bond

b)

Hydrogen bond

c)

Ionic bond

d)

Metallic bond

33.

How many hydrogen bonds are involved in holding these strands of DNA together?

a)

11

b)

9

c)

8

d)

4

34.

which nucleotides are considered purines?

a)

adenine & thymine

b)

cytosine & guanine

c)

adenine & guanine

d)

cytosine & thymine

35.

one strand of DNA reads 5'-AAAGTTCCG-3'

the complementary strand would read:

a)

3'-TTTCAAGGC-5'

b)

3'-CGGAACTTT-5'

c)

5'-TTTCAAGGC-3'

36.

DNA replicates during

a)

G1 phase

b)

G2 phase

c)

S phase

d)

Prophase

37.

Replication of centriole occurs in

a)

Interphase

b)

Prophase

c)

Metaphase

d)

Anaphase

38.

Chromosomes are separated during?

a)

Prophase

b)

Anaphase

c)

Metaphase

d)

Telophase

39.

Which statement describes event during intephase of mitosis?

a)

Chromosomes start to coil, becoming shorter and fatter

b)

Chromosomes line up on the equator of the spindle

c)

Chromatids are pulled apart by spindle fiber

d)

Chromosomes are replicated ready for the next division

40.

The diagram shows the chromosomes in a nucleus

What are the Z?

a)

chromatid

b)

centriol

c)

centromere

d)

centrosome

41.

Which process occur by mitosis?

  1. Cloning of plasma cell
  2. Gamete reproduction
  3. Reducing damaged cell
a)

1,2,3

b)

1 and 3 only

c)

2 only

d)

3 only

42.

Chromosomes are arranged along equator during

a)

Prophase

b)

Metaphase

c)

Anaphase

d)

Telophase

43.

The diagrams show chromosomes at the different stage of mitosis.

Which shows the correct of the cell cycle?

a)

W-X-Y-Z

b)

X-Y-Z-W

c)

Y-Z-W-X

d)

Z-W-X-Y

44.

If a cell has 24 chromosomes, how many chromosomes will each of its daughter cells have after mitosis?

a)

12

b)

6

c)

20

d)

24

45.

what is the final phase of mitosis?

a)

G2 phase

b)

cytokinesis

c)

telophase

d)

prophase

46.
The causes of cancer may include which of the following?
a)
chemical carcinogens
b)
UV radiation
c)
inheritance
d)
all of these
47.
What phase does this diagram show?
a)
Interphase
b)
Prophase
c)
Metaphase
d)
Cytokinesis 
48.
What phase does this diagram show?
a)
Metaphase
b)
Interphase
c)
Anaphase
d)
Telophase
49.
What phase does this diagram show?
a)
Interphase
b)
Metaphase
c)
Prophase
d)
Telophase
50.
What phase does this diagram show?
a)
Cytokinesis
b)
Telekinesis
c)
Phenokinesis
d)
Psychokinesis
51.
What phase does this diagram show?
a)
Interphase
b)
Telophase
c)
Prophase
d)
Metaphase
52.
What are the four phases of mitosis?
a)
Interphase, Prophase, Metaphase, Telophase
b)
Prophase, Metaphase, Anaphase, Cytokinesis
c)
Interphase, Prophase, Metaphase, Cytokinesis
d)
Prophase, Metaphase, Anaphase, Telophase
53.
During interphase _________________.
a)
the mitotic spindle appears
b)
two new daughter cells are formed
c)
the mature cell prepares itself by making a copy of DNA
d)
a new nuclear membrane appears and the mitotic spindle disappears
54.
During what phase does the mitotic spindle appear and the nuclear membrane disappear? 
a)
Interphase
b)
Mitosis 
c)
Prophase
d)
Metaphase
55.
During the metaphase, the ________________ line up in the middle, and each attaches to one of the spindle fibers. 
a)
nucleus
b)
cell wall
c)
chromosomes
56.

Which letter represents Prophase?

a)

A

b)

B

c)

C

d)

D

57.

Which letter represents Metaphase?

a)

A

b)

B

c)

C

d)

D

58.

Which letter represents Anaphase?

a)

A

b)

B

c)

C

d)

D

59.

Which letter represents Telophase?

a)

A

b)

B

c)

C

d)

D

60.

What feature is the arrow pointing to?

a)

Cleavage Furrow

b)

Mitosis Indentation

c)

Pinch Point

d)

Cell Split Point

61.

When does the cytosol and organelles split and divide into two identical copies?

a)

Cytokinesis

b)

Telophase

c)

Interphase

d)

G-Phase

62.

In general terms, virus replication involves how many broad stages which are present in all viruses?

a)

2

b)

3

c)

5

d)

6

63.

How many chromosomes will a normal human have after a complete cell cycle?

a)

23

b)

46

c)

47

d)

92

64.

What is the longest stage of the cell cycle?

a)

Interphase

b)

Mitosis

c)

Cytokinesis

d)

Prophase

65.

What is feature unique to plant cells will appear during telophase and cytokinesis?

a)

Cleavage Furrow

b)

Cell Plate

c)

Peptidoglycan

d)

Nuclear Membrane

66.

What is one of the main proteins that will signal a cell to divide?

a)

Mitogen

b)

Mitotic Signalation

c)

Norepinephrine

d)

Dopamine

67.

What is Interphase?

a)

structure that holds the sister chromatids together.

b)

the phase of the cell cycle in which the nucleus and its contents divide.

c)

the phase in which the cytoplasm and its contents divide.

d)

the period during the cell cycle of a cell’s growth and development.

68.

What is a Centromere?

a)

structure that holds the sister chromatids together.

b)

the phase of the cell cycle in which the nucleus and its contents divide.

c)

the phase in which the cytoplasm and its contents divide.

d)

the period during the cell cycle of a cell’s growth and development.

69.

What is Mitosis?

a)

structure that holds the sister chromatids together.

b)

the phase of the cell cycle in which the nucleus and its contents divide.

c)

the phase in which the cytoplasm and its contents divide.

d)

the period during the cell cycle of a cell’s growth and development.

70.

What is Cytokinesis?

a)

structure that holds the sister chromatids together.

b)

the phase of the cell cycle in which the nucleus and its contents divide.

c)

the phase in which the cytoplasm and its contents divide.

d)

the period during the cell cycle of a cell’s growth and development.

71.

What might happen if cytokinesis did not occur after mitosis?

a)

The cell becomes stronger because it has two sets of organelles.

b)

The cell becomes heavier because it has two sets of organelles.

c)

The cells would remain fused together and the new double cell would have duplicates of all parts.

d)

The cell becomes bigger because it has two sets of organelles.

72.

During the cell cycle, the cell’s nucleus and its contents divide to create two ____________.

a)

organelles

b)

organisms

c)

identical daughter cells

d)

organs

73.

Why is the cell cycle so important?

a)

because it helps for growth and develop

b)

because it replaces cells that are old or damaged

c)

because it produces new cells

d)

All of the above

74.

Where does the cell spend most of its life?

a)

prophase

b)

anaphase

c)

interphase

d)

telophase

75.

Interphase is followed by a shorter phase of the cell cycle called ____________.

a)

mitotic phase

b)

metaphase

c)

telophase

d)

Anaphase

76.

What are the two stages of the Mitotic Phase?

a)

telophase and metaphase.

b)

mitosis and cytokinesis.

c)

anaphase and telophase

d)

telophase and anaphase.

77.

Why is the Cell Cycle often represented as a circle?

a)

Because it is easy to draw

b)

Because cell cycles has a distinct beginning and end point

c)

to highlight the checkpoints

d)

to show that it repeats over and over

78.

In which part of Interphase are the chromosomes replicated?

a)

G0

b)

G1

c)

S

d)

G2

79.

Spinal cord injuries are difficult to treat because damaged nerce cells do not regenerate. Which of the following most accurately explains why damaged nerve cells no longer regenerate?

a)

Mature nerve cells are in a resting state; the no longer divide during mitosis

b)

Nerve damage disrupts the cell cycle at the G1 phase

c)

Nerve damage disrupts the cell cycle at the S phase

d)

Nerve damage prevents centrioles from being synthesized

80.

During which stage of the cell cycle does the nucleus divide?

a)

interphase

b)

mitosis

c)

endocytosis

d)

cytokinesis

81.

Which statement below desribes the events during G2 of Interphase?

a)

The cell grows, develops, and makes new proteins

b)

The DNA replicates to form a new set of identical chromosomes

c)

The cell grows, makes new organelles, and prepares for mitosis

d)

the nucleolus disappears and the nuclear envelope disintegrates

82.

Which stage of the cell cycle is MOST critical for ensuring that daughter cells are identical?

a)

G1

b)

S

c)

Prophase

d)

G2

83.

Which is not a phase of the cell cycle?

a)

Interphase

b)

Mitosis

c)

Cytokinesis

d)

Duplication

84.

Select all stages of interphase?

a)

G1

b)

S

c)

G2

d)

Mitosis

85.

In which stage of the cell cycle does the cell split into two?

a)

Mitosis

b)

G1

c)

Cytokinesis

d)

S

86.

_____ is the uncontrolled growth of cells, often resulting in a tumor or mass of abnormal cells

a)

Cancer

b)

Apoptosis

c)

Radiation

87.

Apoptosis is

a)

programmed cell death

b)

mysterious cell death

c)

programmed cellular mutation

d)

mysterious cellular mutation

88.

If you look at a cell under a microscope, which phase is it MOST likely to be in?

a)

Cytokinesis

b)

M phase

c)

Interphase

d)

G1 Phase

89.
Put the following actions in order: DNA replicates, cell grows, cell divides, cell prepares for mitosis. 
a)
DNA replicates, cell grows, cell prepares for mitosis, cell divides
b)
cell grows, cell prepares for mitosis, DNA replicates, cell divides
c)
cell grows, DNA replicates, cell prepares for mitosis, cell divides
d)
DNA replicates, cell prepares for mitosis, cell grows, cell divides
90.
In the S stage of interphase....
a)
The cell grows
b)
The nucleus divides
c)
The cell membrane divides
d)
The DNA is replicated
91.
Cancer is a consequence of the disruption of the cell cycle
a)
True
b)
False
92.

What does DNA replication mean?

a)

DNA is made.

b)

DNA makes new cells.

c)

DNA copies itself.

d)

DNA starts the cell cycle.

93.

the division of the cytoplasm is called

a)

mitosis

b)

interphase

c)

cytokinesis

d)

somatic

94.

What is the division of the nucleus called?

a)

chromosome

b)

mitotic phase

c)

cytokinesis

d)

the cell cycle

95.
The causes of cancer may include which of the following?
a)
environmental influences
b)
UV radiation
c)
viruses
d)
all of these
96.
When cancer spreads to other tissues of the body, it is called...
a)
Metastasis
b)
Invasiveness
c)
Angiogenesis
d)
Chemotherapy
97.

________________is a critical point where stop and go signals can regulate the cycle

a)

Metastasis

b)

Checkpoint

c)

Malignant

d)

Benign

98.

Cells that rarely divide will spend most of their time in what particular phase of the cell cycle?

a)

Go

b)

G1

c)

G2

d)

S

99.

This check point of the cycle dictates whether the cell will continuously divide or stop, and it also checks the cell size, presence of growth factors and damage of the DNA.

a)

G1 checkpoint

b)

G2 checkpoint

c)

S checkpoint

d)

M checkpoint

100.

In this phase, the cell is preparing for the cell division in the mitotic stage.

a)

Go

b)

G1

c)

G2

d)

S

101.

In the eukaryotic cell, it is the longest stage of the cell cycle and generally its function is to prepare the cell to division process.

a)

Interphase

b)

Mitotic phase

c)

Synthesis Phase

d)

All of the above

102.

DNA replication occurs in what phase of cell cycle?

a)

Interphase

b)

Growth phase

c)

Mitotic phase

d)

Synthesis Phase

103.

Which checkpoint ensures sister chromatids are positioned to be split correctly?

a)

G1 checkpoint

b)

G2 checkpoint

c)

S checkpoint

d)

M checkpoint

104.

In this phase, the cell is preparing for the cell division of the mitotic phase.

a)

Go

b)

G1

c)

G2

d)

S

105.

If the M checkpoint is not cleared, what specific stage of mitosis will be blocked?

a)

Anaphase

b)

Metaphase

c)

Prophase

d)

Telophase

106.

Programmed cell death is known as ____________.

a)

Apoptosis

b)

Oncogene

c)

Proto-oncogene

d)

Tumor suppressor gene

107.

Identify the stage in mitosis

a)

Anaphase

b)

Telophase

c)

Metaphase

d)

Interphase

108.

State the process taking place in the image

(a)  

109.

Which stage of mitosis is taking place in the image?

a)

Anaphase

b)

Telophase

c)

Metaphase

d)

Prophase

110.

What process does DNA undergo when chromosomes condense in prophase?

(a)  

111.

What are the molecules with a regulatory function in the cell cycle whose discovery is an example of serendipity?

(a)  

112.

When in the cell cycle does DNA replication occur?

a)

G1

b)

S phase

c)

G2

d)

Prophase

113.

Which phase of mitosis follows anaphase?

a)

Telophase

b)

Prophase

c)

Metaphase

d)

Cytokinesis

114.

Identify the structure in the image

a)

Sister pair of chromatids

b)

Bivalent

c)

Integral protein

d)

Large circular chromosome

115.

What term describes the ratio between the number of cells in mitosis and the total number of cells?

(a)  

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