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Histopathology- Staining 2- Cytopathology 2

Total questions: 63

Worksheet time: 32mins

Name
Class
Date
1.

What is the use of reticulin stain in histology?

a)

to demonstrate - glycogen

b)

to demonstrate - reticular fibres and basement membrane

c)

to identify acid- fast organisms

d)

all of the above

2.

In reticulin staining, reticulin fibers are stained gives which color to the structure in histology?

a)

red color

b)

blue/ black color

c)

green color

d)

orange color

3.

The detection of ferric iron in tissues, blood smears , or bone marrow smears can be done by using which stain?

a)

reticulin stain

b)

iron stain

c)

PAP stain

d)

H & E stain

4.

What is the clinical application of iron stain in histology?

a)

Hemochromatosis

b)

Liver histopathology

c)

Hemosiderosis

d)

Both A & B

e)

Both A & C

5.

What is the composition of phosphotungstic acid & hematoxylin (PTAH) stain?

a)

phosphotungstic acid with eosin

b)

hematoxylin with phosphotungstic acid

c)

phosphotungstic acid with iron staining

d)

phosphotungstic acid with reticulin stain

6.

After staining the sample with phosphotungstic acid hematoxylin (PTAH) stain, the phosphotungstic acid binds all of the available hematin to form which type of pigment?

a)

white lake pigment

b)

black color in all follicle

c)

blue lake pigment

d)

none

7.

Which specific staining technique, stains the muscle cross striations , fibrin , nuclei and other tissue elements blue?

a)

iron stain

b)

reticulin stain

c)

phosphotungstic acid hematoxylin (PTAH)

d)

PAS stain

8.

What are the clinical application of phosphotungstic acid hematoxylin (PTAH) stain?

a)

contractions bands, as seen in contraction band necrosis

b)

demonstrating striated muscle fibers and mitochondria

c)

tumors of skeletal muscle

d)

gliosis in the central nervous system

e)

All of the above

9.

Fibrin deposits in lesion can be seen by which staining technique in histology?

a)

phosphotungstic acid hematoxylin (PTAH) stain

b)

PAS stain

c)

Reticulin stain

d)

Iron stain

10.

What is the other name of acid fast stain in histology?

a)

reticulin stain

b)

calcium stain

c)

Ziehl Neelsen stain

d)

PAS stain

11.

What all reagents are used in acid fast stain?

a)

Carbol fuchsin

b)

acid alcohol

c)

methylene blue

d)

all of the above

12.

When acid fast bacilli stained with acid fast stain , retain Carbol fuschin , so they appear?

a)

blue color

b)

bright red color

c)

orange color

d)

green color

13.

Only calcium that is bound to an anion (such as PO4 or CO3) can be demonstrated by calcium staining?

a)

true

b)

false

14.

Which of the following stains can be used to detect calcium?

a)

Routine stain (H & E)

b)

Von kossa stain

c)

Alizarin red S

d)

Azan stain

e)

All of the above

15.

Which staining is commonly used in histology to detect abnormal deposit of calcium in the body?

a)

Von Kossa staining

b)

Iron stain

c)

Reticulin stain

d)

all of the above

16.

Calcium forms a green black lake with hematoxylin to give a red color on H & E stain?

a)

true

b)

false

17.

What is the clinical application of Von Kossa stain in histology?

a)

blood vessels

b)

articulations

c)

kidneys

d)

all of the above

18.

The staining of lipids is generally by which staining technique in histology?

a)

PAS stain

b)

Iron staining

c)

Calcium staining

d)

fat staining

19.

In which staining, frozen formalin fixed sections are used instead of paraffin embedded sections in histology?

a)

Iron staining

b)

fat staining

c)

routine staining

d)

reticulin staining

20.

What are the common stains in histology used for fat staining?

a)

Sudan lll

b)

oil red O

c)

iron stain

d)

both A & B

21.

Fat stain used for glyceride impart/ shows which color in histology?

a)

red color

b)

green color

c)

blue color

d)

orange color

22.

Fat staining like , Sudan black B - stains which color in histology?

a)

blue color

b)

black color

c)

red color

d)

green color

23.

What is the process by which all nicks and irregularities in the cutting edge of a knife are removed?

a)

stropping

b)

honing

c)

drilling

d)

brushing

24.

What are the sharpening stones used in the process of honing the knife of the Microtome called?

a)

strops

b)

hones

25.

Jagged edge cause lines or tears in section cutting?

a)

true

b)

false

26.

What are the different types of honing?

a)

Manual procedure

b)

automatic procedure

c)

both A & B

d)

none

27.

Which hone is best for manual honing of Microtome knife?

a)

belgian black vein

b)

arkansas

c)

carborundum

d)

plate glass

28.

Which hone is much coarser than other hones?

a)

Belgian black vein

b)

carborundum

c)

arkansas

d)

plate glass

29.

Which hone is used for badly nicked knives?

a)

arkansas

b)

belgian black vein

c)

carborundum

d)

plate glass

30.

Which hone consists of glass disc or wheel driven by an electric motor?

a)

machine hone

b)

belgian black vein/ Belgium yellow

c)

arkansas

d)

plate glass

31.

In honing, the knife is placed at one end of the hone and pushed diagonally forward with a cutting edge. Which motion is used in honing?

a)

head to toe motion

b)

back end motion

c)

figure of 8 motion

d)

none

32.

Honing process is repeated minimum ------ strokes or until the ragged edges are removed in order to sharpen the microtome blade /knife?

a)

100 strokes

b)

10-20 strokes

c)

50-60 strokes

d)

3-5 strokes

33.

Which of the following statement is incorrect regarding precautions taken during honing the knife of a Microtome?

a)

The hone should be lubricated with oil before using

b)

blade must be kept perfectly flat while honing

c)

pressure should be gentle and steady

d)

after honing , oil should not be wiped off from the knife with xylene

34.

Which of the following statement is incorrect?

  1. 1. Stropping is the process of polishing the already fairly sharpened edge after honing

  2. 2.Stropping is the final technique for sharpening the knife before cutting sections

  3. 3. It brings a somewhat sharp blade to like new condition

  4. 4. A paddle strop made up of horse leather is preferred in stropping

a)

1&2

b)

2 & 3

c)

3 & 4

d)

none

35.

Which type of strops are preffered due their ease?

a)

rigid type

b)

flexible type

c)

hanging type

d)

all of the above

36.

Which type of strops are fixed on wooden piece with handle?

a)

rigid type

b)

flexible type

c)

circular type

d)

cubical type

37.

Which of the following statement is true?

1.During stropping , a small quantity of vegetable oil is applied beneath the leather to keep the strops soft.

  1. In the stropping method , the movement is that of 'toe to heel' ?

a)

1

b)

2

c)

1 & 2

d)

none

38.

Which of the following statement is true?

a)

the action of stropping is same as honing

b)

in stropping of knife , about 12 strokes are required

c)

preliminary stropping is done on the canvass side

d)

all of these

39.

In stropping method, the movement is that of ----- ?

a)

heel to toe

b)

toe to heel

40.

Which of the following statement is false?

a)

the knife edge should be oiled or greased after use to prevent rusting

b)

the knife should be washed and flushed with xylene

c)

both A & B

d)

none

41.

Which of the following is true about cytology?

a)

study of cells of body under a microscope

b)

study of tissues of body under a microscope

c)

study of microorganisms in a culture plate

d)

study of macroscopic anatomy of body organs

42.

Which of the following statement is correct?

a)

cytopathology is slower than histopathology

b)

cytopathology is the rapid test than histopathology

c)

both are of almost same speed

d)

depends on the specimen

43.

All are the advantages of cytopathology except?

a)

simple & inexpensive

b)

rapid technique

c)

no risk to the patients

d)

need confirmation by histopathology

44.

Which of the following are advantages of cytopathology?

a)

replace frozen section or biopsy

b)

confirmation by histopathology

c)

determine the size and type of lesion

d)

interpretation based on overall cell/ tissue observation

45.

In exfoliative cytology, which types of samples are collected from the body?

a)

urine

b)

CSF

c)

sputum

d)

all of the above

46.

What do you mean by exfoliative cytology?

a)

a technique of cytology in which palpable lesions are examined

b)

a technique of cytology in which cells that spontaneously shed in body fluids are examined

c)

a technique of cytology in which scrapings are examined

d)

none

47.

Which of the cytological technique takes samples by scraping?

a)

exfoliative cytology

b)

abrasive cytology

c)

FNAC

d)

both B & C

48.

What is the other name of FNAC?

a)

Fast and narrow aspiration cytology

b)

fine needle aspiration cytology

c)

fine needle abrasive cytology

d)

free and numb abrasive cytology

49.

By which of the following cytology techniques , specimen are collected from deep organs?

a)

abrasive cytology

b)

exfoliative cytology

c)

fine needle aspiration cytology

d)

both A & B

50.

Which of the following is true?

a)

All liquids (urine , body cavity fluids etc.) have to be centrifuged

b)

for FNAC and thick cellular discharges , centrifugation is must

c)

the sediment of the centrifuged liquid must be discarded and must not be used for smear preparation

d)

all of these

51.

What should be the speed at which the liquid samples must be centrifuged before smearing?

a)

4000

b)

3000

c)

2000

d)

1000

52.

Which of the following should be added to coagulable fluids to prevent coagulation in cytopathology?

a)

xylene

b)

EDTA

c)

Formaline

d)

None

53.

Exfoliative cells degenerate rapidly. In delay , these specimens should be fixed in ----- and refrigerated until smear is prepared?

a)

10% alcohol

b)

95% alcohol

c)

20% alcohol

d)

all of the above

54.

Which of the following is added to preserve the samples like urine and other fluids that needs centrifugation in cytopathology?

a)

10% formalin

b)

40% ethyl alcohol

c)

50 % ethyl alcohol

d)

none

55.

Which of the following is used as an adhesive to adhere the body fluid specimens to the glass slide?

a)

Mayer's egg albumin

b)

EDTA

c)

Citates

d)

xylene

56.

Which of the following are types of stains commonly used in different laboratories in cytopathology?

a)

papanicolaou stain

b)

Diff Quick (DQ) stain

c)

H & E stains

d)

all of the above

57.

Which of the following stain is more superior for demonstrating the nuclear details, that are most important and specific in making the diagnosis of malignancy?

a)

h & E stain

b)

Diff quick (DQ) stain

c)

Modified ZN stain

d)

Papanicolaou stain

58.

Which stain has advantage of both papanicolaou and modified Romanowsky stain in cytopathology?

a)

PAS stain

b)

H & E stain

c)

Modified ZN Stain

d)

Fouchet's test

59.

Which stain needs one minute to perform and is used for microorganisms , cytoplasm and background material staining?

a)

H & E stain

b)

Modified Romanowsky stain

c)

PAS stain

d)

papanicolaou stain

60.

In which stain, slides are fixed in basic ethanol- based solution in cytopathology?

a)

H & E stain

b)

Modified Romanowsky stain

c)

Papanicolaou stain

d)

Diff quick (DQ) stain

61.

Which of the following is true about PAP stain?

a)

used to differentiate cells in gynecological specimens

b)

includes only basic dyes

c)

cannot stain nucleus

d)

contains only one dye

62.

What are the objectives of papanicolaou stain in cytopathology?

a)

definition of nuclear details

b)

transparency of cytoplasm

c)

differentiation of cells

d)

all of the above

63.

What is the color imparted to cell nuclei by the hematoxylin in PAP staining?

a)

orange

b)

black

c)

Pink

d)

Blue