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WorksheetsDigestion Quiz - Docs
Total questions: 60
Worksheet time: 3600secs
Which of the following are primary mechanical functions of the digestive system?
Mastication
Emulsification
Segmentation
Glycogenesis
Digestion in the cavity (luminal) primarily involves which enzymes?
Salivary amylase
Brush‐border lactase
Pancreatic lipase
Enterocyte aminopeptidase
Brush‐border digestion occurs on enterocyte microvilli and includes:
Sucrase–isomaltase
Pepsin
Maltase
Trypsin
The submucosal (Meissner’s) plexus mainly regulates:
Secretion
Motility
Blood flow
Swallowing reflex
The myenteric (Auerbach’s) plexus is located between:
Mucosa and submucosa
Circular and longitudinal muscle layers
Serosa and muscle layers
Epithelium and lamina propria
Sensory neurons in the enteric nervous system detect:
pH changes
Chyme distension
Blood glucose
Luminal osmolarity
Parasympathetic vagal stimulation of the gut uses which neurotransmitter?
Norepinephrine
Acetylcholine
Serotonin
VIP
Sympathetic inhibition of gut motility primarily involves:
β₂‐receptors on smooth muscle
M₃‐receptors on parietal cells
α₁‐receptors on sphincters
H₂‐receptors on parietal cells
Gastrin is secreted by G cells in response to:
Gastric acid
Amino acids in stomach
Duodenal fats
Vagal GRP
CCK release is stimulated by:
Luminal H⁺
Long‐chain fatty acids
Glucose absorption
Amino acids and peptides
Secretin is released from S cells when duodenal pH falls below:
3.5
4.5
5.5
6.5
GIP has which effect?
Stimulates insulin release
Inhibits gastric acid
Stimulates motilin release
Increases gastric motility
Somatostatin secreted by D cells inhibits all EXCEPT:
Gastrin release
Acid secretion
Pancreatic enzyme release
Hepatic bile secretion
Chewing reflex is triggered by:
Stretch receptors in masseter
Periodontal mechanoreceptors
Vagal afferents only
Taste‐bud activation
The pharyngeal phase of swallowing is:
Voluntary
Involuntary
Controlled by CN IX & X
Controlled by the enteric plexus
The upper esophageal sphincter at rest prevents:
Air entry into stomach
Gastric reflux
Esophageal peristalsis
Food entering pharynx
Primary esophageal peristalsis is triggered by:
Pharyngeal swallow
Esophageal distension
Enteric reflex only
Colonic mass movements
Secondary peristalsis in the esophagus is initiated by:
Pharyngeal input
Local distension receptors
Vagal motor output
Pyloric reflex
Basal salivary flow rate is approximately:
0.1 mL/min
0.4 mL/min
1.0 mL/min
2.0 mL/min
At high salivary flow, saliva becomes:
Hypotonic
Higher Na⁺ & Cl⁻
Lower K⁺ & HCO₃⁻
Approaches plasma composition
Parotid saliva is primarily:
Serous
Mucous
Mixed
Viscous
Salivary α-amylase acts on:
Starch
Proteins
Lipids
Lactose
Gastric slow waves occur at:
1–2/min
3–5/min
6–8/min
10–12/min
Antral peristaltic contractions are initiated by:
Slow waves reaching threshold
Enteric nervous bursts
Vagal parasympathetic only
Gastrin peaks
Gastric emptying is slowed by:
Duodenal acid
Hyperosmolar chyme
High fat in duodenum
Increased fundic tone
Parietal cells secrete HCl by exchanging H⁺ for which ion?
Na⁺
K⁺
Cl⁻
Ca²⁺
Carbonic anhydrase in parietal cells:
Hydrolyzes pepsinogen
Forms H₂CO₃ from CO₂ + H₂O
Converts CO₂ to urea
Releases intrinsic factor
Cl⁻ enters the parietal cell from blood via:
HCO₃⁻/Cl⁻ antiporter
Na⁺/Cl⁻ cotransporter
Passive Cl⁻ channel
CFTR on basolateral side
ACh stimulates acid via which receptor subtype?
M₁
M₂
M₃
M₄
Histamine’s action on parietal cells is via:
H₁ receptor
H₂ receptor
Gq‐coupled pathway
Gs‐coupled pathway
Somatostatin inhibits acid by:
Raising cAMP
Lowering cAMP
Blocking H₂ receptors
Suppressing gastrin release
PPIs act by:
Blocking H₂ receptors
Inhibiting H⁺/K⁺-ATPase
Increasing somatostatin
Reducing proton-pump insertion
The cephalic phase accounts for about what percent of meal acid?
10%
30%
60%
80%
Parietal cells secrete HCl by exchanging H⁺ for which ion?
Na⁺
K⁺
Cl⁻
Ca²⁺
Gastric-phase acid secretion is triggered by:
Antral distension
Peptides in stomach
Duodenal fat
Duodenal acid
Intestinal-phase acid secretion involves:
Secretin inhibiting gastrin
CCK stimulating acid
Enterogastric reflexes
Pancreatic enzymes
Prodromal symptoms of vomiting include:
Retching
Nausea
Salivation
Diarrhea
The chemoreceptor trigger zone (CTZ) is activated by which nerves?
Vagal nerves
Splanchnic nerves
Sciatic nerve
Enteric plexus
Motion‐sickness vomiting is mediated by afferents from which system?
Vagus nerve
Glossopharyngeal nerve
Vestibular apparatus
Splanchnic nerves
Which dietary protein is “incomplete” due to lysine deficiency?
Egg white
Soy protein
Corn protein
Beef protein
Primary esophageal peristalsis is initiated by:
Pharyngeal swallowing reflex
Local esophageal distension
Gastrocolic reflex
Colonic mass movements
Serotonin (5-HT) released by enterochromaffin cells in the gut primarily:
Stimulates gastric acid secretion
Enhances pancreatic enzyme release
Initiates peristaltic reflexes via enteric neurons
Inhibits migrating motor complexes
The intrinsic pace of gastric slow waves (~3–5/min) is generated by:
Smooth-muscle cells
Submucosal plexus neurons
Interstitial cells of Cajal
Parietal cells
Which bile constituent directly neutralizes acidic chyme in the duodenum?
Bile salts
Sodium bicarbonate
Cholesterol
Lecithin
The average duration of one chewing cycle is about:
0.2–0.4 s
0.8–1.2 s
2–3 s
5 s
The average duration of one chewing cycle is about:
0.2–0.4 s
0.8–1.2 s
2–3 s
5 s
The pharyngeal phase of swallowing is mediated by which cranial nerves?
Trigeminal (V)
Facial (VII)
Glossopharyngeal (IX)
Vagus (X)
The lower esophageal sphincter consists of:
Skeletal muscle
Smooth muscle
Striated muscle
Fibrous tissue
Receptive relaxation of the stomach involves:
Sympathetic reflexes
Enteric short reflexes
Vago-vagal reflexes
Motilin release
The liver produces roughly how much bile per day under basal conditions?
250 mL
500 mL
1.0 L
2.0 L
Salivary lysozyme contributes to oral defense by:
Hydrolyzing starch
Cleaving peptidoglycan
Activating pepsinogen
Emulsifying fats
How many basic taste modalities are classically recognized?
Three
Four
Five
Six
The myenteric (Auerbach’s) plexus primarily controls:
Mucosal secretion
Smooth-muscle tone & motility
Hormone release
Salivary secretion
GLP-1 from L cells promotes:
Insulin secretion
Gastric emptying
Satiety
Glucagon release
Motilin is highest during:
Fed state
Fasting interdigestive periods
Gastric phase
Intestinal phase
The vago-vagal reflex during swallowing causes:
LES relaxation
Fundic contraction
Pyloric tightening
UES opening
Receptive relaxation maintains low gastric pressure until about:
200 mL
500 mL
1.5 L
3.0 L
Peripheral vomiting afferents travel via:
Vagus nerve
Splanchnic nerves
Sciatic nerve
Enteric plexus
Hepatic bile contains all of the following except:
Bile salts
Cholesterol
Bilirubin
Pancreatic lipase
Which transporter mediates active uptake of bile salts in the terminal ileum?
ASBT (Apical Sodium‐Bile acid Transporter)
NTCP (Na⁺‐Taurocholate Cotransporting Polypeptide)
SGLT1 (Sodium‐Glucose Linked Transporter 1)
PEPT1 (H⁺‐Peptide Cotransporter)
