WorksheetsStudy Guide for BIOS 256 - Week 2: Digestive System II
Total questions: 96
Worksheet time: 48mins
The anatomical structures of the lower GI tract and its accessory organs include:
Esophagus, stomach, liver, pancreas
Small intestine, large intestine, rectum, liver, pancreas, gallbladder
Pharynx, esophagus, stomach, spleen
Mouth, pharynx, esophagus, appendix
What is the main function of the small intestine?
90% of digestion and nutrient absorption.
Production of bile for fat emulsification.
Storage of undigested food material.
Absorption of water and electrolytes only.
Which of the following is NOT a section of the small intestine?
Duodenum
Jejunum
Ileum
Colon
Which feature of the small intestine slows chyme movement?
Villi
Microvilli
Circular folds
Lacteals
What is the function of villi in the small intestine?
Villi contain blood capillaries and lacteals.
Villi secrete digestive enzymes into the stomach.
Villi produce insulin for glucose regulation.
Villi store bile for fat digestion.
Which structure forms the brush border and houses enzymes in the small intestine?
Microvilli
Villi
Goblet cells
Crypts of Lieberkühn
Which hormone is secreted by S-cells and stimulates the pancreas to secrete bicarbonate?
Secretin
Gastrin
Insulin
Glucagon
Which hormone stimulates bile secretion?
Secretin
CCK
GIP
Motilin
What is the function of GIP secreted by K-cells?
Inhibits acid/motility, stimulates insulin.
Stimulates gastric acid secretion.
Increases gastric motility.
Inhibits insulin secretion.
Motilin, secreted by Mo-cells, increases what function in the digestive system?
Gut motility (MMC)
Gastric acid secretion
Bile production
Insulin release
Which section of the small intestine is responsible for bile and pancreatic enzyme entry and has a focus on digestion?
Duodenum
Jejunum
Ileum
Cecum
Which section of the small intestine is villi-rich and is associated with nutrient absorption and Celiac Disease?
Jejunum
Duodenum
Ileum
Colon
Which section of the small intestine is responsible for B12 and bile salt absorption and is associated with Peyer's patches and Crohn's Disease?
Ileum
Duodenum
Jejunum
Cecum
What are the parts of the large intestine in order?
Cecum → Colon (ascending → transverse → descending → sigmoid) → Rectum → Anus
Cecum → Rectum → Colon (ascending → transverse → descending → sigmoid) → Anus
Colon (ascending → transverse → descending → sigmoid) → Cecum → Rectum → Anus
Rectum → Cecum → Colon (ascending → transverse → descending → sigmoid) → Anus
What is the main function of the large intestine?
Absorbs remaining water/electrolytes, forms feces
Produces digestive enzymes
Breaks down proteins into amino acids
Absorbs most nutrients from food
What does the appendix contain and what does it store?
Contains lymphoid tissue, stores beneficial gut flora
Contains digestive enzymes, stores bile
Contains muscle tissue, stores vitamins
Contains nerve cells, stores hormones
What is the first step in the defecation reflex?
Rectal stretch → baroreceptors
Relaxation of the internal anal sphincter
Contraction of abdominal muscles
Activation of external anal sphincter
What is the second step in the defecation reflex?
Signal to spinal cord
Relaxation of anal sphincter
Absorption of water in colon
Contraction of abdominal muscles
Which enzyme is responsible for breaking down carbohydrates?
Salivary amylase, pancreatic amylase, sucrase, maltase, lactase
Pepsin, trypsin, chymotrypsin, carboxypeptidase
Lipase, phospholipase, cholesterol esterase
DNA polymerase, RNA polymerase, helicase, ligase
What is the end product of carbohydrate digestion?
Monosaccharides (glucose, fructose, galactose)
Amino acids
Fatty acids and glycerol
Disaccharides
Which enzymes are involved in protein digestion?
Pepsin, trypsin, chymotrypsin, aminopeptidase, dipeptidase
Amylase, maltase, lactase, sucrase, lipase
DNA polymerase, RNA polymerase, ligase, helicase, primase
Lipase, bile salts, pancreatic lipase, colipase, phospholipase
What is the end product of protein digestion?
Amino acids
Fatty acids
Glucose
Nucleotides
Which enzyme is responsible for fat digestion?
Lingual/gastric/pancreatic lipase
Amylase
Pepsin
Trypsin
Bile salts emulsify fats and are absorbed into lacteals as what?
Chylomicrons
Micelles
Triglycerides
Fatty acids
Which enzyme is responsible for nucleic acid digestion?
Pancreatic nucleases
Pepsin
Amylase
Lipase
What is the end product of nucleic acid digestion?
Nucleotides → bases, sugar, phosphate
Amino acids
Fatty acids and glycerol
Monosaccharides
Which minerals are absorbed by active transport in the digestive system?
Iron and calcium
Sodium and potassium
Magnesium and zinc
Phosphorus and chloride
What is the mechanism for water absorption in the intestine?
Osmosis
Active transport
Facilitated diffusion
Endocytosis
Where are bile salts reabsorbed in the digestive system?
Ileum
Duodenum
Stomach
Jejunum
Which of the following vitamins are synthesized by the gut microbiome?
Vitamin C
Vitamin K
Vitamin D
Vitamin B12
Folate
The gut microbiome ferments fiber to produce what?
Short-chain fatty acids
Amino acids
Glucose
Bile acids
Which of the following is NOT a function of the gut microbiome?
Synthesizes vitamins
Ferments fiber
Controls peristalsis
Supports immune function
Which reflex is responsible for increased colon motility when food enters the stomach?
Gastrocolic
Enterogastric
Gastroileal
The enterogastric reflex slows gastric emptying when food enters the duodenum.
True
False
What is the trigger for the cephalic phase of digestion?
Sight/smell
Swallowing food
Absorption in the small intestine
Release of bile
What is the action during the cephalic phase of digestion?
Prepares stomach (HCl, motility)
Absorbs nutrients in the small intestine
Breaks down fats in the mouth
Neutralizes acid in the duodenum
What is the trigger for the gastric phase of digestion?
Food in stomach
Sight of food
Absorption of nutrients
Release of bile
What is the action during the gastric phase of digestion?
Increases secretions
Decreases motility
Inhibits enzyme production
Reduces acid secretion
What is the trigger for the intestinal phase of digestion?
Chyme in duodenum
Saliva in mouth
Pepsin in stomach
Bile in gallbladder
What is the action during the intestinal phase of digestion?
Releases secretin, CCK
Inhibits bile production
Stimulates gastric acid secretion
Promotes salivary amylase release
What initiates defecation?
Rectal stretch activates baroreceptors
Contraction of the diaphragm
Relaxation of the esophageal sphincter
Inhibition of gastric acid secretion
What do enteroendocrine cells secrete?
Secretin, CCK, GIP, Motilin
Pepsin, Trypsin, Amylase, Lipase
Insulin, Glucagon, Somatostatin, Pancreatic Polypeptide
Histamine, Serotonin, Dopamine, Acetylcholine
What does bile do?
Emulsifies fats for easier digestion
Breaks down proteins into amino acids
Absorbs water from digested food
Produces insulin for blood sugar regulation
What is needed for B12 absorption?
Intrinsic factor
Pepsin
Amylase
Bile salts
Best place to auscultate bowel sounds?
RLQ near ileocecal valve
LUQ near spleen
RUQ near liver
LLQ near sigmoid colon
Function of gastrin?
Increases HCl secretion and gastric motility
Decreases HCl secretion and gastric motility
Stimulates insulin secretion
Inhibits bile production
Most common factor in hemorrhoids?
Increased abdominal pressure
Low blood sugar
Decreased heart rate
Vitamin C deficiency
Low calcium levels
What is the main pathophysiology of Gastroesophageal Reflux Disease (GERD)?
Malfunction of the Lower Esophageal Sphincter (LES) allows stomach acid to flow into the esophagus.
Infection of the stomach lining
Blockage of the intestines
Overproduction of bile
Which of the following is NOT a recommended lifestyle modification for GERD?
Maintain healthy weight
Elevate head of bed while sleeping
Eat large meals before bedtime
Avoid smoking & alcohol
Fill in the blank: To help manage GERD, it is recommended to avoid _______ & alcohol.
smoking
exercise
water
vegetables
Which foods should be avoided to help manage GERD?
Spicy, fried, citrus, and chocolate foods
Whole grains, lean meats, and non-citrus fruits
Low-fat dairy, steamed vegetables, and bananas
Oatmeal, apples, and grilled chicken
Which of the following is a medical treatment for GERD?
Antibiotics
Antacids (e.g., Tums)
Insulin
Beta-blockers
Which of the following is an H2 blocker used in the treatment of GERD?
Ranitidine
Omeprazole
Aspirin
Metformin
Name one type of medication used as a medical treatment for GERD.
Proton pump inhibitors (PPIs)
Antihistamines
Beta blockers
Insulin
Which of the following is NOT a cause of peptic ulcers?
Helicobacter pylori
NSAIDs
Alcohol, smoking, stress
Vitamin C deficiency
Fill in the blank: _______ is a bacterium that can cause peptic ulcers.
Helicobacter pylori
Escherichia coli
Streptococcus pneumoniae
Bacillus subtilis
Which of the following is a type of peptic ulcer found in the stomach?
Gastric Ulcer
Duodenal Ulcer
Esophageal Ulcer
Oral Ulcer
Where are duodenal ulcers located?
Duodenum
Stomach
Esophagus
Colon
What is a common treatment for Gallstones?
Cholecystectomy (gallbladder removal)
Appendectomy (appendix removal)
Coronary bypass surgery
Tonsillectomy (tonsil removal)
Which of the following is NOT a symptom of Gallstones?
Severe pain
Jaundice
Diarrhea
Pancreatitis
Fill in the blank: A symptom of Gallstones is ________ pain.
Severe
Mild
Intermittent
Dull
Which of the following is a symptom of Celiac Disease?
Jaundice
Bloating
Pancreatitis
Impaired fat digestion
What is the cause of Celiac Disease?
Autoimmune response to gluten (gliadin) that damages intestinal villi
Bacterial infection of the small intestine
Deficiency of digestive enzymes
Excessive intake of dietary fiber
Name one symptom of Celiac Disease.
Diarrhea
Headache
Rash on hands only
Frequent urination
What is a strict gluten-free diet used to treat?
Celiac Disease
Diabetes
Hypertension
Asthma
Which of the following is a treatment for inflammation in Celiac Disease?
Cholecystectomy
Steroid medications
Antibiotics
Insulin
Pancreatitis is a symptom of Gallstones.
True
False
Anemia is a symptom of Celiac Disease.
True
False
Which of the following is a symptom of Crohn's Disease?
Fatigue
High blood pressure
Headache
Rash
Which of the following is a symptom of Crohn's Disease?
Abdominal cramps
Sore throat
Blurred vision
Dizziness
Which of the following is a symptom of Crohn's Disease?
Chronic diarrhea
Fever
Cough
Back pain
Which of the following is a symptom of Crohn's Disease?
Blood/mucus in stool
Chest pain
Swelling in legs
Hair loss
Which of the following is a symptom of Crohn's Disease?
A) Joint inflammation
B) Hearing loss
C) Skin rash
D) Insomnia
Which of the following is a risk factor for Crohn's Disease?
Genetics
High cholesterol
Lack of exercise
Excessive sun exposure
Which of the following is a risk factor for Crohn's Disease?
Smoking
Alcohol abuse
Sedentary lifestyle
High sugar intake
Which of the following is a risk factor for Crohn's Disease?
NSAID use
Vitamin C deficiency
Overeating
Dehydration
Which of the following is a risk factor for Crohn's Disease?
Family history
Poor hygiene
Excessive exercise
Low protein diet
Which of the following is a complication of Crohn's Disease?
Anal fissures
Asthma
Diabetes
Hypertension
Which of the following is a complication of Crohn's Disease?
Fistulas
Cataracts
Osteoporosis
Migraine
Which of the following is a complication of Crohn's Disease?
Ulcers
Kidney stones
Anemia
Allergies
Which of the following is a complication of Crohn's Disease?
Malnutrition
Obesity
Scurvy
Appendicitis
Which of the following is a complication of Crohn's Disease?
Bowel obstruction
Heart attack
Stroke
Glaucoma
Which of the following is a complication of Crohn's Disease?
Colorectal cancer
Liver cirrhosis
Gallstones
Bronchitis
Diverticulitis is most common in which age group?
Children under 10
Teenagers
Adults over age 40
Adults under 30
Which of the following is NOT a risk factor for diverticulitis?
Obesity
Smoking
High-fiber diet
Sedentary lifestyle
Which of the following are symptoms of diverticulitis?
Abdominal pain and fever
Cough and sore throat
Headache and dizziness
Chest pain and palpitations
Fever is a symptom of diverticulitis.
True
False
Which quadrant of the abdomen is most commonly affected by pain in diverticulitis?
Left lower quadrant (LLQ)
Right upper quadrant (RUQ)
Right lower quadrant (RLQ)
Left upper quadrant (LUQ)
Which of the following is a complication of diverticulitis?
Diabetes
Abscesses
Hypertension
Asthma
Fill in the blank: Bowel perforation is a ________ of diverticulitis.
complication
treatment
symptom
prevention
What is the recommended treatment for mild diverticulitis?
Short-term liquid diet
Immediate surgery
High-fiber diet during acute phase
Long-term antibiotic therapy
Fill in the blank: One of the severe treatments for colorectal cancer is _________
Bowel resection
Physical therapy
Antibiotics
Acupuncture
Fill in the blank: A surgical procedure that may be required in severe cases of colorectal cancer is called _________.
Colostomy
Appendectomy
Gastrectomy
Cholecystectomy
Which of the following is a risk factor for colorectal cancer?
Age < 30
Age ≥ 50
High physical activity
Low body weight
Fill in the blank: A family history is considered a ________ for colorectal cancer.
risk factor
treatment
cure
symptom
Which lifestyle habit increases the risk of colorectal cancer?
Smoking
Regular exercise
Drinking water
Eating fruits
