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Obstructive Lung Disease

Total questions: 45

Worksheet time: 45mins

Name
Class
Date
1.

Which of the following are side effects of treating asthma with a beta 2 agonist (select 2)?

a)

Bradycardia

b)

Tremors

c)

Hypokalemia

d)

Dysarthria

e)

Hypocalcemia

2.

Which of the following Spirometry data is correct? (select 2)

a)

FEV1/FVC 65% can be COPD

b)

FEV1/FVC 65% can be Asthma

c)

FEV1/FVC > 80% can be Emphysema

d)

FEV1/FVC > 80% can be Chronic Bronchitis

3.

A healthy patient presents on the day of an elective, non-urgent procedure with severe URI symptoms such as fever, purulent rhinitis, and productive cough. According to the COLDS assessment tool and anesthesia best practice, when should the patient undergo the elective surgery?

a)

Proceed as scheduled with an LMA and deep extubation to reduce airway stimulation

b)

Delay surgery by 1 week

c)

Delay 24-48 hours after symptoms improve

d)

Delay the elective case approximately 6 weeks.

4.

A 62 year old man with COPD is undergoing laparoscopic colectomy under general anesthesia on VCV. 30 minutes into the procedure, peak airway pressures rise, wheezing is heard, and capno shows an upsloping expiratory limb with progressively increasing EtCO2. No circuit/ETT kink, mucus plug, or mainstem intubation are detected, which ventilatory settings is the best next step to address this?

a)

decrease the RR to prolong expiratory time

b)

Increase RR to 20 to “blow off” CO2 quicker.

c)

Increase PEEP from 8 to 12 cm H2O.

d)

Switch to desflurane to enhance bronchodilation.

5.

Which of the following pulmonary function test findings is most consistent with obstructive lung disease?

a)

FEV1/FVC ratio of 75%

b)

FEV1 95% of predicted

c)

FEV1/FVC ratio of 60%

d)

DLCO 22 mL/min/mm H

6.

Out of the listed spirometry results, which one correlated the most with obstructive lung disease and its characteristics?

a)

Increased Inspiratory Reserve Volume

b)

Unchanged Residual Volume

c)

Increased FEV1/FVC ratio

d)

Decreased FEV1/FVC ratio

7.

A 65-year-old female smoker with severe COPD is coming in for thoracic surgery. The patient's records show FEV1/FVC <0.5 and PaCO₂ >50 mmHg, for a better patient outcome and COPD-specific anesthesia plan. What postoperative strategy is best suited for this patient?

a)

Extubate immediately to decrease ventilator dependence.

b)

Implement spirometry, chest physiology therapy, and titrate FiO2 for an SpO2 around 90%.

c)

Rapid correction of hypercarbia before induction

d)

Use desflurane for faster emergence.

8.

Which pulmonary function test measures the diffusion of gases across the alveolar membrane?

a)

FVC

b)

MVV

c)

FEV1/FVC Ratio

d)

DLCO

9.

A 58 year old male patient presents in preop for total knee arthroplasty. Patient reports rhinorrhea that started 4 days ago. Patient does not have asthma or any previous respiratory history. Anesthesia plan is general anesthesia with an ETT. What is this patient's COLDS score for assessing perioperative risk?

a)

5

b)

11

c)

14

d)

25

10.

A 68-year-old female with a long history of smoking comes to the clinic because of ongoing shortness of breath and daily cough with sputum. Her arterial blood gas on room air shows a PaO2 of 52 mm Hg and PaCO2 of 50 mm Hg, and her hematocrit is 56%. Based on current guidelines, which treatment would provide the greatest long-term survival benefit for this patient with COPD?

a)

Long-term oxygen therapy

b)

theophylline therapy

c)

Administration of inhaled corticosteroids with antibiotic use

d)

Long term Methylxanthines use

11.

A 72-year-old female with known bronchiectasis is admitted with hemoptysis of 250 mL over the past 24 hours. What is the most appropriate next step in management?

a)

Prepare for selective bronchial arterial embolization

b)

Increase frequency of chest physiotherapy

c)

Administer Guaifenesin 50 mg q4hr

d)

Give platelets

12.

A 16-year-old patient with a history of cystic fibrosis (CF) presents for an emergent laparoscopic appendectomy. The patient has thick pulmonary secretions and decreased breath sounds bilaterally. The anesthetic plan of care includes general anesthesia with endotracheal intubation. Which of the following medications should the CRNA avoid administering during this case?

a)

Fentanyl

b)

Rocuronium

c)

Glycopyrrolate

d)

Ondansetron

13.

A 45-year-old woman with a history of asthma is undergoing a laparoscopic hysterectomy under general anesthesia. Shortly after insufflation, the CRNA notices PIP 40, SpO2 85%, and up-sloping on the ETCO2 waveform. Which of the following interventions should the CRNA perform to treat a bronchospasm? (Select 3)

a)

Administer albuterol via the anesthesia circuit

b)

Deepen the level of anesthesia with a volatile agent

c)

Administer epinephrine if bronchospasm is severe and unresponsive

d)

Perform a jaw thrust to relieve upper airway obstruction

e)

Administer a beta-blocker to reduce airway reactivity

14.

Which is NOT a classic presentation of COPD?

a)

Loss of elastic recoil

b)

Increase in Total Lung Capacity

c)

Decrease in Residual Volume

d)

Irreversible airflow limitation

15.

Which characteristic is the most common chronic medical condition in the world, characterized by bronchial hyperactivity and bronchoconstriction that is reversible?

a)

Obstructive Lung Disease

b)

Asthma

c)

Pulmonary Function Test

d)

Restrictive Lung Disease

16.

A 48-year-old male presented to the pre-operative area for a THA. In the past two months he has states that he has become short of breath when walking his dog in the morning. He is a non-smoker. Upon further question, the patient admits that his wife of 10 years is a heavy smoker and smoke near him. He has a known familial history of Alpha-1 Antitrypsin deficiency. What differential diagnosis can be strongly considered in your Anesthesia Plan of Care?

a)

Asthma

b)

COPD

c)

Restrictive Lung Disease

d)

One Lung Ventilation

17.

What gas does the DLCO pulmonary function test utilize?

a)

Carbon monoxide

b)

Helium & Oxygen Mixture (Heliox)

c)

Xenon

d)

Nitrous oxide

18.

Your patient with severe COPD comes in for a laparoscopic appendectomy. The patient is sedated with general anesthesia and an endotracheal tube is placed. During the case, you notice that your peak & plateau pressures are rising and your waveform is not returning to baseline. What action(s) should you take? Select all that apply.

a)

Increase the respiratory rate

b)

Change your I:E ratio from 1:2 to 1:3

c)

Disconnect the patient circuit from the ventilator

d)

Increase tidal volume

19.

Which of the following is contraindicated in patients with asthma undergoing anesthesia due to risk of bronchospasm?

a)

Propofol

b)

Sevoflurane

c)

Atracurium

d)

Ketamine

20.

A 65-year-old man with severe COPD (FEV1/FVC ratio < 0.5, PaCO2 55 mmHg) is scheduled for an open abdominal surgery. Which of the following perioperative management strategies is most appropriate?

a)

Aggressively preload with fluids to minimize risk of hypotension during anesthesia

b)

Use desflurane for rapid emergence and reduced myocardial depression

c)

Target postoperative SpO2 ~90% and avoid rapid correction of hypercarbia

d)

Extubate early to minimize risk of ventilator associated pneumonia

21.

For a central airway obstruction, how would the flow volume loop present?

a)

Obstructive pattern

b)

Fixed pattern

c)

Intrinsic pattern

d)

Minimized pattern

22.

Your patient is a 16-year-old female that presents with an autosomal recessive disorder, with her sweat chloride levels at 78, and is coughing up thick, sticky secretions. Which of these interventions is least helpful to her anesthetic management?

a)

Glycopyrrolate

b)

Liberal fluid administration

c)

Bronchodilators

d)

Heated high flow nasal cannula

23.

A 62-year-old man with GOLD stage III COPD presents for an elective laparoscopic cholecystectomy. He continues to smoke and has dyspnea on exertion. Preop evaluation reveals FEV1 40% of predicted and PaCO₂ of 50. Which ventilation strategy is best to minimize hyperinflation and auto-PEEP?

a)

Increase respiratory rate with low tidal volume

b)

Use prolonged expiratory time with low respiratory rate

c)

Add PEEP to offset auto-PEEP

d)

Use a large tidal volume to ensure adequate ventilation

24.

What is the most common organism cultured in patients with bronchiectasis?

a)

Pseudomonas

b)

Streptococcus pneumoniae

c)

Haemophilus influenzae

d)

Staphylococcus aureus

25.

A 65-year-old female with a 10-year history of COPD (FEV1 45% predicted) presents for an elective inguinal hernia repair. She reports to using 2 pillows at night, dyspnea on exertion, chronic cough with sputum production, and frequent hospitalizations for exacerbations. Preoperative ABG on room air: pH 7.36, PaCO2 56 mmHg, PaO2 61mmHg, HCO3- 31. Her resting SpO2 is 92% on RA. Which of the following intraoperative management strategies is most appropriate for this patient?

a)

Use of low tidal volumes and prolonged expiratory times to prevent air trapping

b)

Administration of high FiO2 to maintain PaO2 > 100 mmHg

c)

Use of high respiratory rate to maintain normocapnia

d)

Avoidance of regional anesthesia due to risk of hypoventilation

26.

During induction of anesthesia in a patient with a history of asthma, which of the following induction agents is most appropriate?

a)

Atracurium

b)

Neostigmine

c)

Morphine

d)

Propofol

27.

Your patient suddenly develops high peak airway pressures, wheezing, desaturation, and an upslope in ETCO₂ waveform during anesthesia. What is the most likely cause?

a)

Laryngospasm

b)

Bronchospasm

c)

Acute upper respiratory tract infection

d)

Decrease cardiac output

28.

Which of the following drugs should be avoided in patients with asthma?

a)

Dobutamine

b)

Tramadol

c)

Ketorolac

d)

Cisatracurium

29.

A 5-year-old girl comes in for her scheduled myringotomy surgery. During the preop exam you notice she is wheezing, has purulent green drainage out of her nose and having a hard time answering questions due to tachypnea. She has no other medical history. Which anesthetic plan is best for this situation?

a)

Proceed with surgery ensuring she gets 2 albuterol treatments prior to induction and ensure to induce with Desflurane

b)

Administer IV Morphine to bring her respiratory rate down to an acceptable range

c)

Delay the surgery recommend consult to pulmonology

d)

Intubate immediately and proceed with surgery

30.

Why do patients with asthma who are treated only with inhaled corticosteroids generally not require perioperative stress-dose steroid supplementation?

a)

Inhaled corticosteroids improve immune function

b)

Inhaled corticosteroids rarely cause significant hypothalamic-pituitary-adrenal (HPA) axis suppression

c)

Inhaled corticosteroids are rapidly metabolized in the liver

d)

Inhaled corticosteroids increase endogenous cortisol production

31.

A 58-year-old man with a 40–pack-year smoking history is scheduled for elective hernia repair in 2 weeks. He quit smoking yesterday after being counseled by his surgeon. On preoperative evaluation, his carboxyhemoglobin levels are decreased, and his oxygen-carrying capacity has improved. Which of the following statements best reflects the clinical significance of his short-term smoking cessation?

a)

His risk of postoperative pulmonary complications is significantly reduced after 24 hours of abstinence

b)

Short-term cessation improves oxygen delivery but does not significantly lower postoperative pulmonary risk

c)

Ciliary function and sputum clearance normalize within 48 hours of smoking cessation

d)

His immune response to pulmonary infection is restored within 1 week of cessation

32.

Which are the signs of intraoperative bronchospasm? (select 3)

a)

Desaturation

b)

Increase peak airway pressure

c)

ETCO2 wave forms not returning to baseline

d)

Wheezing

33.

Select the preferable induction agent for an asthmatic patient who completed treatment for pneumonia one week ago.

a)

Etomidate

b)

Thiopental

c)

Propofol

d)

Ketamine

34.

You are preparing to perform anesthesia for an elective adrenotonsillectomy on a 9-year-old male. Upon examining him in pre-op, you gather the following data from your assessment: HR- 97, BP- 93/59, SpO2- 94% on RA, Temp: 38.2 °C, RR: 22. Physical examination reveals purulent nasal drainage and a productive cough. His mother states, "He's been dealing with this head cold for the past 5 days". Which of the following interventions would be most appropriate for the CRNA to take?

a)

Pretreat the patient with an albuterol + antihistamine treatment

b)

Cancel anesthesia and recommend reschedule for 6 weeks later

c)

Proceed with the procedure utilizing RSI on induction

d)

Proceed with the procedure utilizing an LMA to decrease the airway instrumentation

35.

You are caring for a 65-year-old female with a history of severe asthma. Before surgery, she was given an albuterol breathing treatment. Post-treatment, her peak expiratory flow was greater than 80% predicted, she exhibited no wheezing on auscultation, and her oxygen saturation was 98% on room air. The patient progresses through the case with stable vital signs until she suddenly begins to desaturate to 79% on 35% FiO2. You notice elevated peak airway pressures (50 cm H2O) and an upsloping pattern on the ETCO2 monitor. All of the following interventions would be appropriate in this situation, EXCEPT:

a)

Administer a second nebulized albuterol treatment via ET tube

b)

Increase FiO2 to 100%

c)

Deepen anesthesia with IV morphine

d)

Administer 1.5mg/kg of IV Lidocaine

36.

A 45-year-old man with a history of asthma undergoes general anesthesia for an inguinal hernia repair. During the case, peak airway pressures suddenly rise, the capnography tracing shows an upsloping endtidal CO₂ waveform, and wheezing is heard on auscultation. Which of the following is the most appropriate initial management step?

a)

Administer IV corticosteroids

b)

Deepen the level of anesthesia

c)

Give IV magnesium sulfate

d)

Administer epinephrine

37.

A 32-year-old patient with a history of moderate persistent asthma presents for laparoscopic cholecystectomy. Which of the following induction agents is most appropriate to minimize the risk of bronchospasm?

a)

Thiopental

b)

Propofol

c)

Desflurane

d)

Ketorolac

38.

Which pulmonary function test is within normal range?

a)

FVC 2.6 L for a female patient

b)

DLCO of 26 mL/min/mmHg

c)

FEV1/FVC of 82%

d)

FEV1 90% of predicted

39.

This is the EtCO2 waveform of your patient with a history of asthma. What is the most likely cause of this waveform?

a)

Bronchospasm

b)

Negative Pressure Pulmonary Edema

c)

Faulty Inspiratory Valve

d)

Curare Cleft

40.

A 19-year-old patient with Asthma is going to have a Laparoscopic cholecystectomy. She uses her rescue inhaler twice daily for a week. On preop assessment you note mild expiratory wheezing. Which Drug would you want to avoid for this patient?

a)

Propofol

b)

Ketamine

c)

Sevoflurane

d)

Aspirin

41.

You have a patient who will be having a pulmonary function test. On your understanding of this you should know that all of the following are true except:

a)

FVC is normally 3.7 L in Females

b)

FEV1 is volume of air inhaled in 1 second

c)

FEF25-75% reflects small airway function

d)

MVV normal is 140-180 L/min in Males

42.

Which of the following pulmonary function test results is most characteristic of obstructive lung disease such as COPD?

a)

↓ FEV1/FVC ratio (less than 70%)

b)

↑ Total Lung Capacity (TLC)

c)

↓ Diffusion Capacity (DLCO)

d)

Normal FEV1/FVC ratio

43.

A 64-year-old man with a 45-pack-year smoking history is scheduled for an open abdominal aortic aneurysm repair. His preoperative pulmonary function tests show FEV1/FVC ratio of 0.45, FEV1 at 45% predicted, and PaCO₂ of 55 mmHg. Which of the following intraoperative ventilation strategies is most appropriate for this patient?

a)

Low tidal volume (6–8 mL/kg) with prolonged expiratory time to minimize air trapping

b)

No PEEP

c)

Short inspiratory time with rapid respiratory rate

d)

100% FiO₂ throughout surgery

44.

Which of the following medications should be avoided or used cautiously in patients with asthma (Select 3)?

a)

Morphine

b)

Propofol

c)

Ketamine

d)

Aspirin

e)

Beta Antagonists

45.

A 32-year-old male with cystic fibrosis presents for bronchoscopy due to persistent hemoptysis and worsening pulmonary function. He has a history of recurrent Pseudomonas infections and reports increased sputum production despite completing a recent course of antibiotics for pneumonia. On examination, he is afebrile, oxygen saturation is 93% on room air, and bilateral coarse crackles are noted on auscultation. Which of the following anesthetic management strategies is most appropriate to optimize intraoperative care for this patient?

a)

Administer IV furosemide to decrease airway secretions

b)

Avoid suctioning to reduce the risk of exacerbating hemoptysis

c)

Administer high-dose opioids to blunt airway reflexes

d)

Use heated, humidified inspired gases with frequent suctioning