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PHAR 109 Unit 2 Review FA25

Total questions: 46

Worksheet time: 47mins

Name
Class
Date
1.

A SERM is dispensed with a Medication Guide because

a)

there is an increased risk of danger to a developing fetus

b)

there is an increased of infection

c)

there is an increased risk of blood clots

d)

there is an increase risk of stomach ulcers

2.

NSAIDs carry boxed warnings for all the following adverse effects EXCEPT:

a)

increased risk of serious stroke.

b)

increased risk of GI inflammation, ulceration, and bleeding.

c)

increased risk of liver toxicity.

d)

increased risk of serious heart attack.

3.

Patients with Parkinson’s disease have an imbalance of which of the following neurotransmitters?

a)

dopamine and acetylcholine

b)

GABA and glutamate

c)

aspartate and serotonin

d)

glutamate and glycine

4.

Which drug used to treat RA and lupus can cause vision problems?

a)

azathioprine

b)

entanercept

c)

hydroxychloroquine

d)

methotrexate

5.

CNS Stimulants used to treat attention-deficit disorders, such as amphetamine salts, are classified as _____ controlled substances.

a)

C-IV

b)

C-II

c)

C-III

d)

C-V

6.

A patient comes to the Emergency Department with a Tylenol overdose. What will be given to moderate damage?

a)

acetylcholine

b)

acetylcysteine

c)

acetaminophen

d)

aspirin

7.

Common therapy for children and adults with attention-deficit/hyperactivity disorder include the use of which of the following?

a)

CNS depressants

b)

CNS stimulants

c)

acetylcholinesterase inhibitors

d)

5-hydroxytryptophan

8.

Treatment for other conditions can increase the risk or exacerbate gout. All of the following might increase the risk of a gout attack EXCEPT

a)

diuretics

b)

cytotoxic drugs

c)

nicotinic acid

d)

allopurinol

9.

Due to an interaction with some viruses children and adolescents should not take aspirin as they may have the potential to have a reaction known as

a)

Tardive Dyskinesia

b)

Reye's Syndrome

c)

Chicken Pox

d)

Epstein Barr Syndrome

10.

What is the prototype (main example) of a salicylate?

a)

sulfasalazine

b)

diclofenac

c)

salicylism

d)

aspirin

11.

Which of the following drugs used to treat RA is a cytotoxic agent that requires special handling as a hazardous drug?

a)

infliximab

b)

etanercept

c)

methotrexate

d)

anakinra

12.

JAK Inhibitors can be identified by the drug stem

a)

-citinib

b)

-dronate

c)

-cept

d)

-oxifene

13.

TNF Inhibitors can be identified by the drug stem

a)

-citinib

b)

-mab

c)

-oxifene

d)

-cept

14.

The drug stem -dronate identifies drugs in the ______________ class.

a)

bisphosphonate

b)

benzodiazepine

c)

DMARD

d)

SERM

15.

Which of the following is not an example of a disease-modifying antirheumatic drug (DMARD)?

a)

methotrexate

b)

azathioprine

c)

upadacitinib

d)

carisoprodol

16.

To treat rheumatoid arthritis, drugs must be administered that

a)

treat fever.

b)

treat pain.

c)

turn off the immune system.

d)

treat inflammation.

17.

Which of the following should be avoided when taking muscle relaxants?

a)

alcohol

b)

cheeses

c)

grapefruit

d)

antibiotics

18.

What is the mechanism of action for anticholinergic drugs?

a)

increasing dopamine reuptake

b)

blocking acetylcholine receptors

c)

blocking dopamine receptors

d)

blocking norepinephrine receptors

19.

Which of the following conditions is a degenerative disorder of the brain that leads to progressive dementia and changes in personality?

a)

Parkinson’s disease

b)

multiple sclerosis

c)

ADHD

d)

Alzheimer’s disease

20.

Which of the following drugs is not used for Alzheimer’s disease?

a)

donepezil

b)

galantamine

c)

dopamine

d)

memantine

21.

Acetylcholine is a neurotransmitter important in which of the following?

a)

in treating APAP OD

b)

memory, cognition, and muscle movement

c)

as a protectant for the lining of the stomach

d)

in calming the limbic region of the brain

22.

To which class of drugs does acetaminophen belong?

a)

salicylates

b)

antipyretic analgesics

c)

NSAIDs

d)

DMARDs

23.

Which of the following Alzheimer’s disease drugs is commercially available as a transdermal patch under the brand name Exelon?

a)

memantine

b)

rivastigmine

c)

galantamine

d)

donepezil

24.

Poisoning by which of the following drugs has become the most common cause of acute liver failure in the United States?

a)

Ibuprofen

b)

Aspirin

c)

Acetaminophen

d)

Naproxen

25.

What is the drug stem that can be used to identify a COMT Inhibitor?

a)

-ase

b)

-capone

c)

-dopa

d)

-stigmine

26.

What is the most commonly used drug therapy for Parkinson’s disease?

a)

Dopamine

b)

Amantadine

c)

Benztropine

d)

Levodopa

27.

Biologic response modifiers classified as DMARDs may end in any of the following suffixes except?

a)

-cept

b)

-coxib

c)

-mab

d)

-citinib

28.

Which of the following drugs is an NSAID?

a)

Diazepam

b)

Allopurinol

c)

Ibuprofen

d)

Cyclosporine

29.

Common therapy for children and adults with attention-deficit/hyperactivity disorder include the use of which of the following?

a)

CNS depressants

b)

CNS stimulants

c)

acetylcholinesterase inhibitors

d)

5-hydroxytryptophan

30.

Due to an interaction with some viruses, children and adolescents should not take aspirin as they may have the potential to have a reaction known as

a)

Tardive Dyskinesia

b)

Reye's Syndrome

c)

Chicken Pox

d)

Epstein Barr Syndrome

31.

NSAIDs can cause damage to which of the following organs?

a)

skin

b)

liver

c)

kidneys

d)

heart

32.

Which of the following would be the least likely to increase risk of bleeding?

a)

ibuprofen

b)

aspirin

c)

naproxen

d)

celecoxib

33.

Which NSAID has an oral liquid form and is suitable for children?

a)

acetaminophen

b)

aspirin

c)

naproxen

d)

ibuprofen

34.

Which of the following is a narrow therapeutic index drug?

a)

febuxostat

b)

allopurinol

c)

colchicine

d)

probenacid

35.

Which of the following is an over-the-counter product thought, but not conclusively proven, to improve memory for patients with Alzheimer’s disease?

a)

glucosamine

b)

St. John’s wort

c)

ginkgo biloba

d)

chondroitin

36.

What enzyme degrades acetylcholine?

a)

ACh

b)

cholinesterase

c)

monoamine oxidase

d)

COMT

37.

What is the proper storage for denosumab?

a)

refrigerate

b)

freeze

c)

room temperature

d)

with hazardous drugs

38.

_____ are a class of drugs that have analgesic, antipyretic, and anti-inflammatory effects.

a)

NSAIDs

b)

Antibiotics

c)

Beta-blockers

d)

Antacids

39.

Patients who have an allergy to sulfa drugs or salicylates should avoid which of the following drugs?

a)

sulfasalazine

b)

aspirin

c)

azathioprine

d)

chloroquine

40.

All of the following are responses to stimulation of the sympathetic nervous system except:

a)

increase saliva and digestive enzymes

b)

bronchodilation

c)

dilation of pupils

d)

slowing urine production and bladder contractions

41.

A SERM is used to treat:

a)

Rheumatoid Arthritis

b)

Gout

c)

Osteoarthritis

d)

Osteoporosis

42.

Which medication is commonly prescribed to reduce uric acid levels in patients with gout?

a)

acetaminophen

b)

methotrexate

c)

ibuprofen

d)

allopurinol

43.

Which of the following drugs is most likely to cause gastrointestinal ulcers as a side effect?

a)

Levodopa

b)

Memantine

c)

Acetaminophen

d)

Ibuprofen

44.

Which medication is classified as a disease-modifying antirheumatic drug (DMARD)?

a)

Allopurinol

b)

Acetaminophen

c)

Ibuprofen

d)

Sulfasalazine

45.

Match the following

a)

TNF Inhibitor

1.

-cept

b)

Bisphosphonate

2.

-dronate

c)

JAK Inhibitor

3.

-citinib

d)

Benzodiazepine

4.

-azepam/-azolam

e)

Salicylate

5.

-sal

46.

Match the following

a)

Dry Mouth, Urinary Retention, Constipation, Blurred Vision

1.

Anticholinergic Side effects

b)

Over dose can cause Hepatotoxicity

2.

acetaminophen

c)

Antidote for acetaminophen toxicity (OD)

3.

acetylcysteine

d)

Enzyme that breaks down acetylcholine

4.

cholinesterase

e)

Activates Parasympathetic Response

5.

cholinergic agonist