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WorksheetsPHAR 109 Unit 2 Review FA25
Total questions: 46
Worksheet time: 47mins
A SERM is dispensed with a Medication Guide because
there is an increased risk of danger to a developing fetus
there is an increased of infection
there is an increased risk of blood clots
there is an increase risk of stomach ulcers
NSAIDs carry boxed warnings for all the following adverse effects EXCEPT:
increased risk of serious stroke.
increased risk of GI inflammation, ulceration, and bleeding.
increased risk of liver toxicity.
increased risk of serious heart attack.
Patients with Parkinson’s disease have an imbalance of which of the following neurotransmitters?
dopamine and acetylcholine
GABA and glutamate
aspartate and serotonin
glutamate and glycine
Which drug used to treat RA and lupus can cause vision problems?
azathioprine
entanercept
hydroxychloroquine
methotrexate
CNS Stimulants used to treat attention-deficit disorders, such as amphetamine salts, are classified as _____ controlled substances.
C-IV
C-II
C-III
C-V
A patient comes to the Emergency Department with a Tylenol overdose. What will be given to moderate damage?
acetylcholine
acetylcysteine
acetaminophen
aspirin
Common therapy for children and adults with attention-deficit/hyperactivity disorder include the use of which of the following?
CNS depressants
CNS stimulants
acetylcholinesterase inhibitors
5-hydroxytryptophan
Treatment for other conditions can increase the risk or exacerbate gout. All of the following might increase the risk of a gout attack EXCEPT
diuretics
cytotoxic drugs
nicotinic acid
allopurinol
Due to an interaction with some viruses children and adolescents should not take aspirin as they may have the potential to have a reaction known as
Tardive Dyskinesia
Reye's Syndrome
Chicken Pox
Epstein Barr Syndrome
What is the prototype (main example) of a salicylate?
sulfasalazine
diclofenac
salicylism
aspirin
Which of the following drugs used to treat RA is a cytotoxic agent that requires special handling as a hazardous drug?
infliximab
etanercept
methotrexate
anakinra
JAK Inhibitors can be identified by the drug stem
-citinib
-dronate
-cept
-oxifene
TNF Inhibitors can be identified by the drug stem
-citinib
-mab
-oxifene
-cept
The drug stem -dronate identifies drugs in the ______________ class.
bisphosphonate
benzodiazepine
DMARD
SERM
Which of the following is not an example of a disease-modifying antirheumatic drug (DMARD)?
methotrexate
azathioprine
upadacitinib
carisoprodol
To treat rheumatoid arthritis, drugs must be administered that
treat fever.
treat pain.
turn off the immune system.
treat inflammation.
Which of the following should be avoided when taking muscle relaxants?
alcohol
cheeses
grapefruit
antibiotics
What is the mechanism of action for anticholinergic drugs?
increasing dopamine reuptake
blocking acetylcholine receptors
blocking dopamine receptors
blocking norepinephrine receptors
Which of the following conditions is a degenerative disorder of the brain that leads to progressive dementia and changes in personality?
Parkinson’s disease
multiple sclerosis
ADHD
Alzheimer’s disease
Which of the following drugs is not used for Alzheimer’s disease?
donepezil
galantamine
dopamine
memantine
Acetylcholine is a neurotransmitter important in which of the following?
in treating APAP OD
memory, cognition, and muscle movement
as a protectant for the lining of the stomach
in calming the limbic region of the brain
To which class of drugs does acetaminophen belong?
salicylates
antipyretic analgesics
NSAIDs
DMARDs
Which of the following Alzheimer’s disease drugs is commercially available as a transdermal patch under the brand name Exelon?
memantine
rivastigmine
galantamine
donepezil
Poisoning by which of the following drugs has become the most common cause of acute liver failure in the United States?
Ibuprofen
Aspirin
Acetaminophen
Naproxen
What is the drug stem that can be used to identify a COMT Inhibitor?
-ase
-capone
-dopa
-stigmine
What is the most commonly used drug therapy for Parkinson’s disease?
Dopamine
Amantadine
Benztropine
Levodopa
Biologic response modifiers classified as DMARDs may end in any of the following suffixes except?
-cept
-coxib
-mab
-citinib
Which of the following drugs is an NSAID?
Diazepam
Allopurinol
Ibuprofen
Cyclosporine
Common therapy for children and adults with attention-deficit/hyperactivity disorder include the use of which of the following?
CNS depressants
CNS stimulants
acetylcholinesterase inhibitors
5-hydroxytryptophan
Due to an interaction with some viruses, children and adolescents should not take aspirin as they may have the potential to have a reaction known as
Tardive Dyskinesia
Reye's Syndrome
Chicken Pox
Epstein Barr Syndrome
NSAIDs can cause damage to which of the following organs?
skin
liver
kidneys
heart
Which of the following would be the least likely to increase risk of bleeding?
ibuprofen
aspirin
naproxen
celecoxib
Which NSAID has an oral liquid form and is suitable for children?
acetaminophen
aspirin
naproxen
ibuprofen
Which of the following is a narrow therapeutic index drug?
febuxostat
allopurinol
colchicine
probenacid
Which of the following is an over-the-counter product thought, but not conclusively proven, to improve memory for patients with Alzheimer’s disease?
glucosamine
St. John’s wort
ginkgo biloba
chondroitin
What enzyme degrades acetylcholine?
ACh
cholinesterase
monoamine oxidase
COMT
What is the proper storage for denosumab?
refrigerate
freeze
room temperature
with hazardous drugs
_____ are a class of drugs that have analgesic, antipyretic, and anti-inflammatory effects.
NSAIDs
Antibiotics
Beta-blockers
Antacids
Patients who have an allergy to sulfa drugs or salicylates should avoid which of the following drugs?
sulfasalazine
aspirin
azathioprine
chloroquine
All of the following are responses to stimulation of the sympathetic nervous system except:
increase saliva and digestive enzymes
bronchodilation
dilation of pupils
slowing urine production and bladder contractions
A SERM is used to treat:
Rheumatoid Arthritis
Gout
Osteoarthritis
Osteoporosis
Which medication is commonly prescribed to reduce uric acid levels in patients with gout?
acetaminophen
methotrexate
ibuprofen
allopurinol
Which of the following drugs is most likely to cause gastrointestinal ulcers as a side effect?
Levodopa
Memantine
Acetaminophen
Ibuprofen
Which medication is classified as a disease-modifying antirheumatic drug (DMARD)?
Allopurinol
Acetaminophen
Ibuprofen
Sulfasalazine
Match the following
TNF Inhibitor
-cept
Bisphosphonate
-dronate
JAK Inhibitor
-citinib
Benzodiazepine
-azepam/-azolam
Salicylate
-sal
Match the following
Dry Mouth, Urinary Retention, Constipation, Blurred Vision
Anticholinergic Side effects
Over dose can cause Hepatotoxicity
acetaminophen
Antidote for acetaminophen toxicity (OD)
acetylcysteine
Enzyme that breaks down acetylcholine
cholinesterase
Activates Parasympathetic Response
cholinergic agonist
