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Hematologic Abnormalities

Total questions: 71

Worksheet time: 36mins

Name
Class
Date
1.

Which of the following is a classification of abnormalities?

a)

Cell number

b)

Cell morphology

c)

Both A and B

d)

None of the above

2.

Abnormalities can be characterized by increased cellularity, which is called ________.

a)

hypercellular

b)

hypocellular

c)

acellular

d)

metaplastic

3.

Abnormalities can be characterized by decreased cellularity, which is called ________.

a)

hypocellular

b)

hypercellular

c)

normocellular

d)

acellular

4.

Abnormalities can be characterized by absent cellularity, which is called ________.

a)

aplastic

b)

hyperplastic

c)

dysplastic

d)

neoplastic

5.

The image shown is an example of which type of abnormality characterization?

a)

Hypercellular

b)

Hypocellular

c)

Aplastic

6.

Fill in the blank: ________ is defined as less than 25% myeloid cells.

a)

Aplasia

b)

Hyperplasia

c)

Leukemia

d)

Myelofibrosis

7.

Fill in the blank: ________ is basophilia in bone marrow and peripheral blood.

a)

Basophilic hyperplasia

b)

Eosinophilic infiltration

c)

Neutrophilic leukocytosis

d)

Lymphocytic proliferation

8.

Fill in the blank: ________ is abnormal erythrocyte maturation.

a)

Dyserythropoiesis

b)

Erythrocytosis

c)

Leukopoiesis

d)

Thrombocytopenia

9.

Fill in the blank: ________ is abnormal granulocyte maturation.

a)

Dysgranulopoiesis (dysmyelopoiesis)

b)

Erythropoiesis

c)

Thrombocytosis

d)

Leukocytosis

10.

Fill in the blank: ________ is abnormal megakaryocyte or thrombocyte maturation.

a)

Dysmegakaryopoiesis (dysthrombopoiesis)

b)

Erythropoiesis

c)

Leukopoiesis

d)

Hemostasis

11.

Fill in the blank: ________ is eosinophilia in bone marrow and peripheral blood.

a)

Eosinophilic hyperplasia

b)

Neutrophilic leukocytosis

c)

Basophilic anemia

d)

Lymphocytic depletion

12.

Fill in the blank: ________ is normal or increased cellularity with a normal or increased absolute neutrophil count and a low M : E ratio.

a)

Erythroid hyperplasia

b)

Myeloid hypoplasia

c)

Aplastic anemia

d)

Leukemoid reaction

13.

Fill in the blank: ________ is normal or decreased cellularity with a normal or decreased absolute neutrophil count and a high M : E ratio.

a)

Erythroid hypoplasia

b)

Myeloid hyperplasia

c)

Leukemoid reaction

d)

Aplastic anemia

14.

Fill in the blank: ________ is normal or increased cellularity with a normal or increased PCV and a high M : E ratio.

a)

Granulocytic hyperplasia

b)

Erythroid hypoplasia

c)

Aplastic anemia

d)

Lymphocytic leukemia

15.

Fill in the blank: ________ is thickening of cortical bone.

a)

Hyperostosis

b)

Osteopenia

c)

Osteomalacia

d)

Osteoporosis

16.

Fill in the blank: ________ is the presence of intact, viable blood cells within the cytoplasm of megakaryocytes.

a)

Megakaryocyte emperipolesis

b)

Megakaryocyte phagocytosis

c)

Megakaryocyte apoptosis

d)

Megakaryocyte endomitosis

17.

Fill in the blank: ________ is an increase in numbers of megakaryocytes in bone marrow.

a)

Megakaryocytic hyperplasia

b)

Erythroid hyperplasia

c)

Granulocytic hypoplasia

d)

Lymphocytic atrophy

18.

Fill in the blank: ________ is an increased presence of cells of the monocyte series.

a)

Monocytic hyperplasia

b)

Lymphocytic atrophy

c)

Eosinophilic infiltration

d)

Neutrophilic depletion

19.

Fill in the blank: ________ is atypical cells with less than 30% blast cells present.

a)

Myelodysplasia

b)

Leukemia

c)

Lymphoma

d)

Polycythemia vera

20.

Fill in the blank: ________ is increased presence of fibrous tissue that replaces hematopoietic tissue.

a)

Myelofibrosis

b)

Leukopenia

c)

Erythrocytosis

d)

Thrombocytopenia

21.

Fill in the blank: ________ is atypical cells with more than 30% blast cells present.

a)

Neoplasia

b)

Anemia

c)

Leukopenia

d)

Thrombocytosis

22.

Fill in the blank: ________ is neutrophilia in bone marrow and peripheral blood.

a)

Neutrophilic hyperplasia, effective

b)

Neutropenia, ineffective

c)

Eosinophilic hyperplasia, effective

d)

Lymphocytic hyperplasia, effective

23.

Fill in the blank: ________ is neutrophilia in bone marrow concurrent with neutropenia in peripheral blood.

a)

Neutrophilic hyperplasia, ineffective

b)

Neutrophilic hypoplasia, effective

c)

Eosinophilic hyperplasia, ineffective

d)

Basophilic hyperplasia, effective

24.

Fill in the blank: ________ is increased presence of active macrophages, often containing phagocytized material.

a)

Reactive macrophage hyperplasia

b)

Lymphoid follicular hyperplasia

c)

Eosinophilic infiltration

d)

Neutrophilic abscess

25.

Fill in the blank: ________ is characterized by infiltration of bone marrow with fibrin exudate without inflammatory cells.

a)

Fibrinous

b)

Suppurative

c)

Granulomatous

d)

Hemorrhagic

26.

Fill in the blank: ________ inflammation is characterized by increased numbers of plasma cells, mature lymphocytes, and mast cells.

a)

Chronic

b)

Acute

c)

Granulomatous

d)

Suppurative

27.

Fill in the blank: ________ inflammation is characterized by increased numbers of macrophages.

a)

Chronic granulomatous

b)

Acute suppurative

c)

Fibrinous

d)

Serous

28.

Fill in the blank: ________ inflammation is characterized by the presence of both macrophages and neutrophils.

a)

Chronic pyogranulomatous

b)

Acute serous

c)

Fibrinous

d)

Granulomatous

29.

What is the common term for neoplasia?

a)

Leukemia

b)

Anemia

c)

Diabetes

d)

Arthritis

30.

Neoplasia is characterized by a predominance of which type of cells in the bone marrow?

a)

Blast cells

b)

Plasma cells

c)

Erythrocytes

d)

Megakaryocytes

31.

Neoplasia can be classified as lymphoproliferative and myeloproliferative.

a)

True

b)

False

32.

What is the primary function of RBCs?

a)

Fight infections

b)

Transport and protect hemoglobin (O2 carrier)

c)

Produce hormones

d)

Store fat

33.

The loss of RBCs each day should equal _________.

a)

production

b)

destruction

c)

absorption

d)

filtration

34.

Which of the following is NOT a cause of anemia?

a)

Decreased production of RBCs

b)

Increased loss or destruction of RBCs

c)

Increased hemoglobin concentration

d)

Condition that involves O2 carrying capacity of RBCs

35.

Anemia may be caused by reduced numbers of RBCs or decreased ________ concentration.

a)

hemoglobin

b)

glucose

c)

calcium

d)

cholesterol

36.

Anemia is a condition that involves the O2 carrying capacity of RBCs.

a)

True

b)

False

37.

Which laboratory test is used to evaluate anemia?

a)

Reticulocyte counts

b)

Erythrocyte indexes

c)

RBC morphology

d)

All of the above

38.

Fill in the blank: Plasma color, turbidity, and total plasma protein concentration are laboratory tests used in the evaluation of _______.

a)

anemia

b)

fractures

c)

hypertension

d)

arthritis

39.

What does MCV stand for in the context of anemia classification?

a)

Mean Corpuscular Volume

b)

Maximum Cell Value

c)

Median Cell Volume

d)

Microcellular Value

40.

What does MCHC stand for in the context of anemia classification?

a)

Mean Corpuscular Hemoglobin Concentration

b)

Mean Cell Hemoglobin Content

c)

Maximum Cellular Hemoglobin Concentration

d)

Mean Corpuscular Hematocrit Count

41.

Bone marrow is responding to the loss of blood in regenerative anemia.

a)

True

b)

False

42.

Most animals exhibit signs of regeneration within how many days from the cause of anemia?

a)

4 to 7 days

b)

1 to 2 days

c)

10 to 14 days

d)

20 to 30 days

43.

What is considered an adequate response in regenerative anemia?

a)

Percentage of reticulocytes greater than or equal to the expected percentage for corresponding PCV

b)

Decrease in white blood cell count below normal range

c)

Increase in platelet count above normal range

d)

Presence of spherocytes in peripheral blood smear

44.

Horses rarely release reticulocytes, so bone marrow evaluations must be done.

a)

True

b)

False

45.

What is nonregenerative anemia?

a)

Bone marrow is unable to respond to blood loss

b)

Bone marrow produces excess blood cells

c)

Blood clots form excessively

d)

Blood pressure increases rapidly

46.

In nonregenerative anemia, reticulocytes are ______ in blood.

a)

absent

b)

increased

c)

normal

d)

fragmented

47.

Which of the following is NOT a common cause of nonregenerative anemia?

a)

Iron deficiency

b)

Ehrlichiosis

c)

Drug toxicity

d)

Hypertension

48.

In nonregenerative anemia, the bone marrow is able to respond to blood loss.

a)

True

b)

False

49.

Which of the following is a common cause of nonregenerative anemia?

a)

Hyperthyroidism

b)

Hypothyroidism

c)

Diabetes

d)

Leukemia

50.

Fill in the blank: _______ are absent in blood in cases of nonregenerative anemia.

a)

Reticulocytes

b)

Neutrophils

c)

Platelets

d)

Erythrocytes

51.

Which of the following is a cause of nonregenerative anemia?

a)

Renal insufficiency

b)

Vitamin C deficiency

c)

Dehydration

d)

Polycythemia

52.

Which type of anemia is characterized by normal-sized RBCs and occurs secondary to acute or chronic disorders?

a)

Normocytic anemia

b)

Macrocytic anemia

c)

Microcytic anemia

53.

Which type of anemia is associated with large RBCs and a transitory increase in response to regenerative anemia?

a)

Normocytic anemia

b)

Macrocytic anemia

c)

Microcytic anemia

54.

Which type of anemia is linked to iron deficiency and small RBCs?

a)

Normocytic anemia

b)

Macrocytic anemia

c)

Microcytic anemia

55.

Fill in the blank: Hemoglobin concentration is dependent upon the ______ present in microcytic anemia.

a)

iron

b)

calcium

c)

glucose

d)

potassium

56.

What does hypochromatic refer to?

a)

Increased hemoglobin concentration

b)

Reduced hemoglobin concentration

c)

Normal levels of hemoglobin

d)

Excessive hemoglobin in RBCs

57.

Which of the following is associated with hypochromatic RBCs?

a)

Iron deficiency

b)

Vitamin B12 deficiency

c)

Folate deficiency

d)

Sickle cell anemia

58.

Normochromic RBCs have ______ levels of hemoglobin.

a)

normal

b)

low

c)

high

d)

variable

59.

Hyperchromatic is not possible as RBCs have a fixed capacity for _______.

a)

hemoglobin

b)

oxygen

c)

glucose

d)

iron

60.

Which type of anemia is characterized by RBC destruction and is usually regenerative?

a)

Hemolytic

b)

Hemorrhagic

c)

Iron Deficiency

d)

Production Disorders

61.

Hemorrhagic anemia is associated with which of the following?

a)

RBC destruction

b)

Acute or chronic blood loss

c)

Microcytic RBCs

d)

Erythropoiesis—reduced or defective

62.

Fill in the blank: Iron Deficiency anemia is characterized by ________ RBCs and low MCHC.

a)

Microcytic

b)

Macrocytic

c)

Normocytic

d)

Spherocytic

63.

Which of the following is NOT a cause of hemorrhagic anemia?

a)

Trauma

b)

Parasites

c)

Erythropoiesis—reduced or defective

d)

GI ulceration

64.

Production Disorders anemia can be caused by which of the following?

a)

Chronic renal disease

b)

Hyperthyroidism

c)

Parvovirus

d)

All of the above

65.

Hemolytic anemia is usually regenerative.

a)

True

b)

False

66.

Which type of anemia is associated with nutritional or chronic blood loss?

a)

Iron Deficiency

b)

Pernicious Anemia

c)

Sickle Cell Anemia

d)

Aplastic Anemia

67.

Fill in the blank: Production Disorders anemia is characterized by erythropoiesis that is ________ or defective.

a)

reduced

b)

increased

c)

accelerated

d)

enhanced

68.

Which of the following is an example of immune-mediated destruction causing hemolytic anemia?

a)

Anaplasma

b)

Autoimmune hemolytic anemia

c)

Leptospira

d)

Onions

69.

Fill in the blank: ________ is an erythrocyte parasite that can cause hemolytic anemia.

a)

Anaplasma

b)

Giardia

c)

Leishmania

d)

Trypanosoma

70.

Which of the following is a bacterial or viral agent that can cause hemolytic anemia?

a)

Babesia

b)

Methylene blue

c)

Feline leukemia virus

d)

Acetaminophen

71.

Fill in the blank: ________ is a toxic exposure that can cause hemolytic anemia.

a)

Onions

b)

Carrots

c)

Potatoes

d)

Lettuce

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