WorksheetsInsulin and Antidiabetic Medications Worksheet
Total questions: 48
Worksheet time: 24mins
Which insulin type has the fastest onset of action?
NPH
Regular
Lispro
Glargine
A nurse gives insulin glargine (Lantus) at bedtime. Which statement is true?
It has a pronounced peak.
It is given with meals.
It cannot be mixed with other insulins.
It acts for 8 hours only.
Which insulin is given IV to treat diabetic ketoacidosis (DKA)?
Lispro
NPH
Regular
Glargine
A patient receiving NPH insulin should eat to prevent hypoglycemia when?
At bedtime
4–12 hours after injection
Immediately after injection
Before bedtime only
Which oral antidiabetic should be held 48 hours before and after contrast dye?
Metformin
Glipizide
Acarbose
Pioglitazone
A patient on metformin reports GI upset. What should the nurse recommend?
Take on an empty stomach.
Take with meals.
Skip doses if nauseated.
Stop drug.
Sulfonylureas (like glipizide) lower blood sugar by:
Increasing insulin release from the pancreas.
Decreasing intestinal absorption of carbohydrates.
Increasing renal glucose excretion.
Blocking hepatic glucose production.
Which diabetes drug class can cause genital yeast infections?
DPP-4 inhibitors
SGLT2 inhibitors
Biguanides
TZDs
Which drug class should be avoided in heart failure?
Sulfonylureas
TZDs (Pioglitazone)
DPP-4 inhibitors
Alpha-glucosidase inhibitors
A patient taking acarbose should be instructed to take it:
Before breakfast only
With the first bite of each meal
At bedtime
On an empty stomach
The nurse knows GLP-1 agonists (liraglutide, semaglutide) often cause:
Weight gain
Weight loss
Hypoglycemia only
Constipation
A patient on liraglutide (Victoza) reports severe abdominal pain. The nurse suspects:
Pancreatitis
Constipation
Liver toxicity
Dehydration
Pioglitazone (Actos) has which common side effect?
Weight loss
Fluid retention and edema
Hypertension
Tachycardia
A patient using insulin lispro should inject it:
1 hour before eating
30 minutes before eating
Right before eating
After eating
Which insulin type is cloudy in appearance?
Lispro
Regular
NPH
Glargine
Which drug increases insulin release only in presence of glucose?
DPP-4 inhibitor
Biguanide
TZD
Sulfonylurea
Which diabetic drug can cause lactic acidosis?
Glipizide
Metformin
Acarbose
Sitagliptin
A nurse teaches a patient on canagliflozin. Which statement shows understanding?
“I’ll watch for signs of yeast infection.”
“I’ll restrict fluids to prevent urination.”
“I should stop if I have constipation.”
“I’ll take it at bedtime.”
The nurse should question which order for a patient with renal failure?
Metformin
Pioglitazone
Liraglutide
Glipizide
Which oral agent must be taken before meals to prevent post-meal hyperglycemia?
Meglitinides (repaglinide)
TZDs
DPP-4 inhibitors
Biguanides
Which antithyroid drug inhibits thyroid hormone synthesis?
Levothyroxine
Propylthiouracil (PTU)
Desmopressin
Prednisone
A serious side effect of PTU is:
Agranulocytosis
Hypoglycemia
Tachycardia
Hypertension
A patient on levothyroxine should take it:
With breakfast
In the morning on an empty stomach
With milk at bedtime
After meals
A nurse gives desmopressin (DDAVP). The expected effect is:
Increased urine output
Decreased urine output
Lower blood sugar
Increased blood sugar
When using vasopressin, the nurse must monitor for:
Hyponatremia
Dehydration
Hypokalemia
Hyperglycemia
Which glucocorticoid may be used for Addison disease?
Hydrocortisone
PTU
Desmopressin
Levothyroxine
Corticosteroid therapy should be tapered because abrupt stopping can cause:
Hypertension
Adrenal crisis
Hyperglycemia
Weight loss
Which side effect is common with long-term corticosteroid use?
Weight loss
Moon face and thin skin
Bradycardia
Hypoglycemia
A nurse gives calcitonin to a patient with hypercalcemia. The expected result is:
Increased calcium levels
Decreased calcium levels
Increased phosphorus
No change
A patient taking prednisone should be taught to:
Avoid crowds
Stop drug if swelling occurs
Limit potassium intake
Stop drug abruptly
Levothyroxine overdose signs include:
Bradycardia
Weight gain
Palpitations and insomnia
Cold intolerance
Which drug can cause hypokalemia and hyperglycemia when used long-term?
Prednisone
Vasopressin
PTU
Metformin
A patient taking fludrocortisone should monitor for:
Fluid overload
Dehydration
Weight loss
Hypotension
Which medication mimics ADH and is used for diabetes insipidus?
Desmopressin
Prednisone
Methimazole
Hydrocortisone
Methimazole is used to treat:
Hypothyroidism
Hyperthyroidism
Adrenal crisis
Diabetes insipidus
A patient taking methimazole should be taught to report:
Sore throat or fever
Weight gain
Constipation
Insomnia
Which diabetic medication class should be taken with food to prevent GI upset?
Biguanides
DPP-4 inhibitors
SGLT2 inhibitors
TZDs
A patient on corticosteroids should include which dietary change?
Increase sodium intake
Increase potassium and calcium
Avoid protein
Restrict fluids
What should be monitored in a patient receiving long-term prednisone?
Vision and urine color
Glucose, weight, infection signs
Hearing and taste
Hair growth
A patient with SIADH taking demeclocycline should be monitored for:
Dehydration
Weight gain
Bradycardia
Hypertension
Which insulin has the longest duration?
Lispro
Regular
NPH
Degludec
A nurse preparing to give insulin detemir knows:
It has no peak
It can be mixed with lispro
It is given IV
It is cloudy
Which oral antidiabetic drug works in the intestine?
Acarbose
Pioglitazone
Sitagliptin
Glipizide
Which drug may mask symptoms of hypoglycemia?
Beta-blockers
Diuretics
ACE inhibitors
Corticosteroids
A patient taking levothyroxine should be taught to avoid:
Iron and calcium supplements near dosing time
Morning administration
Taking it daily
Empty stomach
Which insulin is typically taken twice daily?
NPH
Glargine
Lispro
Regular
A nurse prepares glucagon for a hypoglycemic patient. The expected effect is:
Decreased blood sugar
Increased blood sugar
Increased insulin secretion
Lowered potassium
What is a common side effect of growth hormone therapy (somatropin)?
Hyperglycemia
Hypotension
Hypoglycemia
Hyponatremia
