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WorksheetsQuizabetes - Prelims
Total questions: 20
Worksheet time: 10mins
Distinguishing features between hyperglycemic hyperosmolar state and diabetic ketoacidosis include all of the following except:
Ketosis
Anion gap
Hypotension
Arterial pCO₂
What is the most common pattern of dyslipidemia associated with diabetes mellitus?
Increased triglycerides and decreased HDL
Increased LDL and decreased HDL
Increased VLDL and decreased HDL
Increased triglycerides and increased VLDL
Which of the following is the earliest manifestation of diabetic nephropathy?
Microalbuminuria
Hypocalcemia
Decreased glomerular filtration rate
Increased urine PCR
Falsely high HbA1c levels seen in:
Iron deficiency (Anemia)
Vitamin B12 deficiency
Hemolysis
Splenectomy
A 5 days old male child had an incidental finding for increased blood glucose level which was asymptomatic. The patient underwent a gene analysis and found to have a key enzyme defect that is a part of the glycolytic pathway and was later diagnosed to have MODY 2. Which of the following enzyme is defective?
Hexokinase
Glucokinase
Pyruvate kinase
Phosphofructokinase
All of the following infectious diseases are exclusive for a diabetic patient except.
Emphysematous pyelonephritis
Emphysematous cholecystitis
MRSA diabetic foot
Malignant otitis externa.
Which of the following receptors are involved in lipolysis and thus increasing insulin resistance?
alpha 1 adrenergic receptors
Beta 3 adrenergic receptors
Beta 1 adrenergic recptors
Alpha 3 adrenergic receptors
Which of the following endopeptidases does not cleave proinsulin to form mature insulin?
Proprotein convertase 1/3
Proprotein convertase 2
Carboxy peptidase E
Carboxy peptidase B
Which amino acid residues on hemoglobin is typically glycated to form HbA1c?
valine in beta chain
valine in alpha chain
histidine of beta chain
glycine in alpha chain
Which drug reduces hepatic gluconeogenesis by inhibiting mitochondrial complex 1 ?
Metformin
Glibenclamide
Voglibose
Pioglitazone
Which of the following is incorrect in case of dawn phenomenon?
Decreased gluconeogenesis
Increase in cortisol
Increased gluconeogenesis
Increase in growth hormone
Glucose tolerance factor is
Chromium
Zinc
Vanadium
Manganese
The most common Amino acid that is Glycation to form Advanced glycation end products is
Alanine
Lysine
Valine
histidine
which of the following Diabetic drug has both oral and injectable routes of administration
Acarbose
Insulin
Semaglutide
Dapaglafazolin
Glucokinase has
High Vmax
Low Km
High Km
Low Km and high Vmax
Insulin deficiency causes
increases NADH/NAD ratio
decreases oxaloacetate
increases beta oxidation
All of the above
which of the following is not a method for glucose estimation
Nelson somogyi
Libermann burchard method
Folin WU
King asatoor
Hypoglycemic hormone is
Insulin
Thyroid hormone
ACTH
Glucagon
Incretins includes
Glucagon Like Peptide-1
Gastric inhibitory peptie
both A and B
Only B
Insulin favours
glycogenolysis
Gluconeogenesis
lipogenesis
ketone body synthesis
