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Quizabetes - Prelims

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

Distinguishing features between hyperglycemic hyperosmolar state and diabetic ketoacidosis include all of the following except:

a)

Ketosis

b)

Anion gap

c)

Hypotension

d)

Arterial pCO₂

2.

What is the most common pattern of dyslipidemia associated with diabetes mellitus?

a)

Increased triglycerides and decreased HDL

b)

Increased LDL and decreased HDL

c)

Increased VLDL and decreased HDL

d)

Increased triglycerides and increased VLDL

3.

Which of the following is the earliest manifestation of diabetic nephropathy?

a)

Microalbuminuria

b)

Hypocalcemia

c)

Decreased glomerular filtration rate

d)

Increased urine PCR

4.

Falsely high HbA1c levels seen in:

a)

Iron deficiency (Anemia)

b)

Vitamin B12 deficiency

c)

Hemolysis

d)

Splenectomy

5.

A 5 days old male child had an incidental finding for increased blood glucose level which was asymptomatic. The patient underwent a gene analysis and found to have a key enzyme defect that is a part of the glycolytic pathway and was later diagnosed to have MODY 2. Which of the following enzyme is defective?

a)

Hexokinase

b)

Glucokinase

c)

Pyruvate kinase

d)

Phosphofructokinase

6.

All of the following infectious diseases are exclusive for a diabetic patient except.

a)

Emphysematous pyelonephritis

b)

Emphysematous cholecystitis

c)

MRSA diabetic foot

d)

Malignant otitis externa.

7.

Which of the following receptors are involved in lipolysis and thus increasing insulin resistance?

a)

alpha 1 adrenergic receptors

b)

Beta 3 adrenergic receptors

c)

Beta 1 adrenergic recptors

d)

Alpha 3 adrenergic receptors

8.

Which of the following endopeptidases does not cleave proinsulin to form mature insulin?

a)

Proprotein convertase 1/3

b)

Proprotein convertase 2

c)

Carboxy peptidase E

d)

Carboxy peptidase B

9.

Which amino acid residues on hemoglobin is typically glycated to form HbA1c?

a)

valine in beta chain

b)

valine in alpha chain

c)

histidine of beta chain

d)

glycine in alpha chain

10.

Which drug reduces hepatic gluconeogenesis by inhibiting mitochondrial complex 1 ?

a)

Metformin

b)

Glibenclamide

c)

Voglibose

d)

Pioglitazone

11.

Which of the following is incorrect in case of dawn phenomenon?

a)

Decreased gluconeogenesis

b)

Increase in cortisol

c)

Increased gluconeogenesis

d)

Increase in growth hormone

12.

Glucose tolerance factor is

a)

Chromium

b)

Zinc

c)

Vanadium

d)

Manganese

13.

The most common Amino acid that is Glycation to form Advanced glycation end products is

a)

Alanine

b)

Lysine

c)

Valine

d)

histidine

14.

which of the following Diabetic drug has both oral and injectable routes of administration

a)

Acarbose

b)

Insulin

c)

Semaglutide

d)

Dapaglafazolin

15.

Glucokinase has

a)

High Vmax

b)

Low Km

c)

High Km

d)

Low Km and high Vmax

16.

Insulin deficiency causes

a)

increases NADH/NAD ratio

b)

decreases oxaloacetate

c)

increases beta oxidation

d)

All of the above

17.

which of the following is not a method for glucose estimation

a)

Nelson somogyi

b)

Libermann burchard method

c)

Folin WU

d)

King asatoor

18.

Hypoglycemic hormone is

a)

Insulin

b)

Thyroid hormone

c)

ACTH

d)

Glucagon

19.

Incretins includes

a)

Glucagon Like Peptide-1

b)

Gastric inhibitory peptie

c)

both A and B

d)

Only B

20.

Insulin favours

a)

glycogenolysis

b)

Gluconeogenesis

c)

lipogenesis

d)

ketone body synthesis