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Total questions: 50
Worksheet time: 25mins
What should be done when a woman who is 24 weeks pregnant has a positive antibody screen?
Perform an antibody identification panel; titer if necessary
No need to do anything until 30 weeks gestation
Administer RhIg (Rh immune globulin)
Adsorb the antibody onto antigen-positive cells
A donor bag is half filled during donation when the blood flow stops. Select the correct course of action
Closely observe the bag for at least 3 minutes; if blood flow does not resume, withdraw the needle
Remove the needle immediately and discontinue the donation
Check and reposition the needle if necessary; if blood flow does not resume, withdraw the needle
Withdraw the needle and perform a second venipuncture in the other arm
A major crossmatch and screening cells are 2+ at IS, 1+ at 37C, and negative at the IAT phase. Identify the most likely problem
Combination of antibodies
Cold antibody
Rouleaux
Test error
An EIA screening test for HTLV I/II was performed on a whole-blood donor. The results of the EIA were repeatedly reactive but the confirmatory test was negative. On the next donation, the screening test was negative by two different EIA tests. The donor should be:
Accepted
Deferred
Told that only plasma can be made from his donation
Told to comeback in 6 months
An iron containing heme protein responsible for the peroxidase activity characteristic of azurophilic granules, it accounts for the greenish color of pus.
Hemoglobin
Myoglobin
Lactoferrin
Myeloperoxidase
It binds iron which is an essential nutrients for microbes.
Defensins
Lysozymes
Lactoferrin
Myeloperoxidase
Phagocytosis can be divided into 6 stages - adherence, chemotaxis, engulfment, fusion, phagosome formation, digestion and destruction. arrange the following in order of occurance:
Chemotaxis, adherence, engulfment, phagosome formation, fusion, and digestion and destruction
Chemotaxis, adherence, engulfment, fusion, phagosome formation, and digestion and destruction
Adherence, chemotaxis, engulfment, fusion, phagosome formation, and digestion and destruction
Adherence, chemotaxis, digestion and destruction, fusion, engulfment, phagosome formation
Phagocytes can interact with microorganisms directly via primitive pattern recognition receptors(PRPR) that recognize a wide array of molecules present on the surface of microorganisms. Phagocytes have also been shown to interact indirectly with microorganisms via opsonins that have been deposited on the microbial cell surface.
Both statements are correct
Both statements are false
Only the first statement is correct
Only the second statement is correct
Most potent phagocytic cell and effective at antigen presentation:
Mast cell
Monocyte
Macrophage
Dendritic cell
Which cell is considered to be a bridge between the innate and adaptive immune system?
NK cell
Mast cell
Monocytes, macrophage
T cell
Large granular lymphocyte (LGL) is synonymous with:
B lymphocytes
Natural killer cells
Cytotoxic T cells
Helper T cells
Which statement about basophils is correct?
Have a high concentration of heparin in the granules
Have a high concentration of histamine in the granules
React with two adjacent IgA molecules on the most cells
Are associated with anaphylactic shock
One molecule of IgM complexed to antigen can bind C1 and trigger the activation of the complement. The efficiency of IgM as an activator of the complement resides in its:
Large size
Heavy chain regions
Pentameric structure
High molecular weight
A part of the T cell antigen receptor complex:
CD2
CD3
CD4
CD8
The cytotoxic ability of T cells can be determined by incubating activated CD8+ T cells by radiolabeled ___ target cells. When the CD8+ cells deliver their "lethal hit" and the target cell is lysed, the radioactive label is released and can be detected by a gamma counter.
Cesium 137Cs
Cobalt 60Co
125Iodine
Chromium 51Cr
An antibody that can be obtained through immunization with an antigen which presents various epitopes
Polyclonal ab
Monoclonal ab
Monomeric ab
Pentameric ab
Uniform homogenous antibodies directed to epitopes, not to whole antigen molecules.
Polyclonal ab
Monoclonal ab
A unique amino acid sequence that is common to immunoglobulin molecules of a given class in a given species:
Isotype
Allotype
Idiotype
None of these
The variable portions of each chain are unique to a specific antibody molecule, and they constitute what is known as:
Isotype
Allotype
Idiotype
None of these
It is considered the gold standard in testing for contract dermatitis:
RIST
RAST
FAST
Patch test
It is referred to as congenital thymic hypoplasia which results from defective embryogenesis leading to a reduced (or absent) thymus.
DiGeorge’s syndrome
Wiskott-Aldrich syndrome
X-linked agammaglobulinemia (XLA)
Bruton’s agammaglobulinemia
Which of the following immunodeficiency disorders is associated with the presence of giant cytoplasmic granules that occur as a result of uncontrolled membrane fusion?
Wiskott-Aldrich syndrome
Chronic granulomatous disease
Chediak-Higashi syndrome
Leukocyte adhesion deficiency
Which one of the following immunodeficiency disorders is associated with a defect in the NADPH oxidase system
Severe combined immunodeficiency
Chronic granulomatous disease
Chediak-Higashi syndrome
Leukocyte adhesion deficiency
It is a chronic progressive inflammatory disease autoimmune disease marked by progressive DRYNESS OF THE EYES AND THE MOUTH.
Sjogren’s syndrome
Rheumatoid arthritis
Scleroderma
SLE
The human anti-neutrophil cytoplasmic antibodies (ANCAs), described for the first time in 1982, directed against antigenic components mainly present in:
Primary granules of neutrophils
Secondary granules of neutrophils
Chromatin of neutrophils
Nucleus of neutrophils
True for Orth’s fluid except:
it contains picric acid, strong formaldehyde and glacial acetic acid
it demonstrates rickettsiae and other bacteria
for study of degenerative process of necrosis
preserves myelin better than buffered formalin
This method is preferred when whole eye sections is required.
Dry celloidin method
Wet celloidin method
Gelatin impregnation
Nitrocellulose method
These are cervico-vaginal cells that mimics the appearance of honeycomb.
Parabasal cells
Endometrial cells
Endocervical glandular cells
Pregnancy cells
This is considered as the most widely used autopsy technique.
Ghon
Virchow
Rokitansky
Letulle
This animal is primarily used for the preparation of polyclonal antibody.
Rabbit
Horse
Pig
Mice
Prolonged exposure to benzene may lead to which of the following?
Leukemia
Aplastic anemia
Cancer
Abortion
Silver impregnation technique is useful for the demonstration of which of the following?
Spirochete
Acid Fast Bacilli
Glycogen
Hemosiderin granules
Deparaffinization process is achieved through which of the following solutions?
Alcohol
Xylene
Ammonia water
Acetone
While cutting sections, you have noticed that tissues are cut alternatively thick and thin. Which of the following may cause this?
Tilt of knife is too great
Wax is too hard
Knife is dirty
All of the choices
When stained with Masson Fontana, melanin will yield what color if positive?
Blue
Red
Brown
Black
All of the following statements are true for Carnoy’s Fluid, EXCEPT:
it is considered to be the most rapid fixative
it contains chromic acid and osmium tetroxide
recommended for chromosome, lymph glands and urgent biopsies
it fixes and dehydrates at the same time
The Philippine Medical Technology Act, RA 5527, was approved on:
June 21, 1979
June 21, 1969
June 21, 1959
June 11, 1969
A medical technologist is a person who engages in the work of medical technology under the supervision of a:
pathologist
Licensed physician authorized by DOH in places where there is no pathologist
either of these
neither of these
A medical technologist is not allowed by law to:
head a clinical laboratory
own a laboratory
supervise a laboratory technician
all of these
MEDICAL TECHNICIAN’S rating in the MT board exam:
60 to 74.9%
65 to 74.9%
68 to 74.9%
70 to 74.9%
Any member of the Medical technology Board, if after due hearing, if found guilty of neglect of duty or incompetence can be removed by:
President of the Philippines
CHED commissioner
PRC chairman
Civil service Commissioner
All successful examinees will be required to take their personal oath:
before the president of the Philippines
before a judge
before the president of PAMET
before the board of MT or any person authorized to administer oath
Administrative investigations shall be conducted by:
at least one member of the Board
three members of the Board
at least one member of board with one legal officer
at least two members of board with one legal officer
Any person presenting or attempting to use as his own, the certificate of registration of another medical technologist is violating:
section 15 of RA 5527
section 20 of RA 5527
section 28 of RA 5527
section 29 of RA 5527
Hematoxylin and Eosin staining is an example of what type of staining technique?
Progressive
Regressive
Negative
Silver Impregnation
The most widely used embedding medium has a melting point of _ at a laboratory with a temperature that ranges at 15-18C.
50-54C
54-58C
50-52C
What is the clearance angle for a rotary microtome?
25-30
5-10
15-20
30-35
All of the following are stain for amyloid except
Congo red
Alcian blue
Iodine
None of the choices
Which of the following is/are microanatomical fixatives?
Helly's
Orth's
Newcomers
All of the choices
A good characteristic of a good mounting media is that it should have a refractive index as close to that of the slide's which is _____.
1.518
1.158
1.185
1.815
