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WorksheetsKaplan questions
Total questions: 128
Worksheet time: 2hrs 8mins
A 75-year-old man with a 40-pack-year history of smoking and hypercholesterolemia is diagnosed with severe atherosclerosis. Atherosclerotic occlusion of which of the following arteries would result in insufficient perfusion of the urinary bladder?
External iliac
Inferior epigastric
Internal iliac
Internal pudendal
Lateral sacral
A 36-year-old woman is hospitalized for treatment of a stomach ulcer that has been getting progressively worse over several months. Radiographic studies reveal the site of involvement to be along the greater curvature, approximately 4cm away from the pyloric sphincter. That night, the ulcer perforates, and there is considerable intra-abdominal bleeding. Surgery reveals that the ulcer has eroded through the stomach wall and has damaged the artery supplying the involved region of the stomach. Which artery was likely involved?
Left gastric
Left gastroepiploic
Right gastric
Right gastroepiploic
Short gastric
A woman who recently gave birth has elevated prolactin levels. The gland responsible for secretion of this hormone is derived from which of the following structures?
Cerebral vesicle
Infundibulum
Neurohypophysis
Proctodeum
Rathke's pouch
A previously normal 56-year-old woman comes to the emergency department because of a "flu-like" illness. She complains of nausea and vomiting, unilateral tingling in the leg, and a headache involving the eye and forehead. She is alert and fully oriented. Motor, sensory, gait, and coordination examinations are normal. Cranial nerve examination is normal, aside from the visual field disorder indicated in the plot below. The neurologic examination suggests an occlusion of which of the following vessels?
Left middle cerebral artery
Left posterior cerebral artery
Right middle cerebral artery
Right posterior cerebral artery
Posterior communicating artery
A 49-year-old Vietnamese man is diagnosed with tuberculosis. On physical examination, large flocculent masses are noted over the lateral lumbar back, and a similar mass is located in the ipsilateral groin. This pattern of involvement strongly suggests an abscess tracking along which of the following muscles?
Adductor longus
Gluteus maximus
Gluteus minimus
Piriformis
Psoas major
A 24-year-old man is stabbed in the neck. Neurologic examination reveals left-sided hemiparesis. There is complete loss of discriminatory joint position and vibration sensation below C8 on the left side. On the right side, there is loss of pain and temperature sensation below C8. It ca be expected that an MRI of the cervical spinal cord will show which of the following findings?
A complete transection of the spinal cord
A hemisection of the left side of the cord
A lesion of the dorsal columns of the cord on the left side
A lesion of the lateral funiculus on the left side
Damage to cervical dorsal roots on left side
A 2-year-old boy is brought to the pediatrician by his mother because he has had several episodes of rectal bleeding. Evaluation with a technetium-99m perfusion scan reveals a 3-cm ileal outpouching located 60cm from the ileocecal valve. This structure most likely contains which of the following types of ectopic tissue?
Duodenal
Esophageal
Gastric
Hepatic
Jejunal
A 34-year-old man is examined in the prison infirmary after sustaining a superficial stab wound to the superolateral aspect of the thoracic wall at the level of the third rib. There is little bleeding and no difficulty breathing; however, the medial border of the scapula on the injured side pulls away from the body wall when the arm is raised. In addition, the arm cannot be abducted above the horizontal. Which of the following muscles is paralyzed?
Levator scapulae
Pectoralis minor
Rhomboid major
Serratus anterior
Supraspinatus
A histologist is examining cells arrested at various stages of oogenesis. He discovers a follicle within the stroma of the ovary that has developed an antrum. This follicle would be classified as
Graafian
primary
primordial
secondary
A 54-year-old man has cirrhosis, with obstruction of the portal circulation within the liver. Portal blood could still be conveyed to the caval system via which of the following?
Azygos and hemiazygos veins
Gonadal veins
External iliac veins
Splenic veins
Vesical venous plexus
A 47-year-old man presents to his neurologist with an unsteady, broad-based gait and slow, slurred speech. Neurologic examination reveals dysdiadochokinesia, intention tremor, hypotonia, and nystagmus. The patient's lesion in a brain structure that derives from which of the following embryonic structures?
Diencephalon
Mesencephalon
Metencephalon
Myelencephalon
Telencephalon
A 47-year-old woman with a history of rheumatic fever is examined by her physician. Physical examination is significant for a low-pitched, rumbling, diastolic murmur preceded by an opening snap. The affected valve can be best evaluated by auscultation at which of the following locations?
Left second intercostal space
Left fifth intercostal space
Left lower sternal body border
Right second intercostal space
Right fifth intercostal space
A newborn girl is noted to hae abnormal accommodation of the lens. Further evaluation reveals an abnormal production of aqueous humor. A malformation of the structure responsible for these functions that is continuous posteriorly with the choroid might be due to abnormal development of
Axons of retinal ganglion cells
choroid fissure of the optic stalk
mesoderm surrounding the optic cup
mesoderm surrounding the optic stalk
neuroectoderm of the optic cup
A neuroscientist decides to perform a study that requires him
to increase the concentration of norepinephrine in the cortex of an
animal subject. He does this by electrically stimulating a nucleus
in the brain. Which of the following nuclei is the most important
source of noradrenergic innervation to the cerebral cortex?
Basal nucleus of Meynert
caudate nucleus
locus caeruleus
raphe nucleus
substantia nigra
A surgeon tells a medical student to tap the side of the face of
a patient who just had thyroid surgery. The surgeon is most
worried about damage to which of the following vessels?
Common carotid artery
External carotid artery
Facial vein
Internal jugular vein
Superior and inferior thyroid arteries
A 45-year-old man comes into the emergency department
with abdominal pain that has progressively worsened since the
previous night. He also notes nausea and vomiting, but is afebrile.
Upper gastrointestinal radiographic studies reveal that a loop of
small intestine has passed through the epiploic foramen into the
omental bursa and is constricted by the margins of the foramen as
the intestine fills. The constriction should not be surgically
relieved by opening the epiploic foramen because this procedure
would risk cutting the
abdominal aorta
hepatic artery
hepatic vein
hypogastric plexus
pancreatic duct
A 26-year-old man is stabbed in the left chest during a bar
brawl. Several days after he is treated, he returns to the physician
complaining of decreased function in his left arm. Physical
examination reveals a winged left scapula and an inability to raise
his left arm above the horizontal. Which of the following nerves
is most likely affected?
axillary
long thoracic
lower subscapular
suprascapular
thoracodorsal
A patient is transported to the emergency department with a
knife wound to the right fifth intercostal space at the midaxillary
line. Which of the following structures is likely to have been
damaged?
liver
right atrium
right pulmonary artery
superior vena cava
upper lobe of right lung
A couple comes to the physician for advice about
contraception and family planning. The physician provides advice
about various methods of birth control. While discussing the
option of using an intrauterine device, a discussion of the process
of implantation comes up. At what stage of embryonic
development does an embryo normally begin to implant in the
endometrium?
blastocyst
four-cell stage
morula
trilaminar embryo
zygote
A newborn male is found to have urethral openings along the
ventral surface of the penis. The physician explains to the parents
that the bilateral structures that should have fused in the midline
failed to fuse completely, and this resulted in the defect. The
parents are very concerned, but the physician reassures them that
this can easily be surgically corrected. Which of the following
structures in a female normally develop from the same structures
that failed to fuse in this boy?
round ligaments of the uterus
crura of the clitoris
labia majora
labia minora
ovarian ligaments
A 19-year-old woman comes to the emergency department
after falling while on roller-blades. There is a 3-cm laceration
over the lateral aspect of the knee penetrating so deep that the
head of the fibula is apparent. A radiograph of the leg is negative
for any fractures. A noticeable foot-drop occurs while the patient
walks. Further examination reveals inability to dorsiflex or evert
the foot. Which of the following best explains her injury?
common peroneal nerve was severed
peroneal muscles were detached from the head of the fibula
superficial peroneal nerve was severed
tibial nerve was severed
A resident physician is performing a pelvic examination on a
young woman. The fingers of one of her hands are in the patient’s
vagina, palpating the cervix. The other hand is pressing on the
abdomen. With the palm of this hand, the physician feels a bony
structure in the lower midline. This structure is most likely the
coccyx
ilium
ischium
pubis
sacrum
A 45-year-old man with a history of stable angina presents to
the emergency department with an episode of chest pain that is
not relieved by rest or nitroglycerin. After stabilization in the
telemetry unit for 2 days, he undergoes a thallium stress test. The
results show reduced perfusion of the lateral wall of the left
ventricle. Which artery is most likely occluded?
left anterior descending
left circumflex
left main coronary
right coronary
A 41-year-old man is injured in a motorcycle accident. He is
taken to the hospital by a rescue helicopter and treated for
abdominal, spinal, and head injuries. Three weeks later he is
examined by a neurologist, who notes that the patient has leftsided
facial swelling and discoloration, slight drooping of the left
eyelid, and a constricted pupil on the left side. There are no other
motor or sensory abnormalities. Which of the following is the
most likely cause of this patient’s ocular disorder?
a lesion of CNVI (6)
a lesion of the midbrain
a lesion of the oculomotor nerve
a lesion of the thoracic spinal cord
myasthenia gravis
A 4-day-old boy is brought to the pediatric clinic because of
breathing difficulties and poor feeding. He coughs, chokes, and
spits up milk very soon after beginning to suckle. Physical
examination and radiographs reveal the presence of the most
common type of tracheoesophageal fistula. The infant’s defect
likely resulted from
failure of the buccopharyngeal membrane to rupture
failure of the tracheoesophageal ridges to fuse
incomplete formation of the septum secundum
incomplete recanalization of the larynx
patent thyroglossal duct
A 40-year-old man complains of loss of sensation over the
right scrotum and on the medial right thigh. Damage to which of
the following nerves would result in such symptoms?
genitofemoral
iliohypogastric
ilioinguinal
lat. cutaneous
pudendal
A neonate has a prominent defect at the base of his spine
through which his meninges and spinal cord protrude. A failure of
which of the following processes is the most common cause of
this type of defect?
development of the body
development of the pedicle
development of primary vertebral ossification centers
development of superior articular process
fusion of vertebral arches
A surgeon is first on the scene after a serious automobile
accident. He finds a passenger bleeding profusely from the neck
and correctly surmises that the bleeding is from the carotid artery.
To control the bleeding, the surgeon can compress the carotid
artery against the anterior tubercle of which of the following
vertebrae?
second cervical
third cervical
fourth cervical
fifth cervical
sixth cervical
An intravenous pyelogram is performed on a patient to
evaluate the function and structure of her kidneys. Examination of
the resulting radiographs reveals that the left kidney is normal but
that there is a duplication of the ureter and renal pelvis on the
right side. Further testing reveals that kidney function is normal.
This variation is a result of abnormal development of which of the
following structures?
allantoic duct
metanephric blastema
mesonephric duct
mesonephric tubules
ureteric bud
MRI reveals that a 62-year-old man has a brain tumor
growing in his interhemispheric fissure at the level of the central
sulcus. The tumor produces neurologic dysfunction of the
cerebral cortex on either side of the tumor. A neurologic
examination of this patient would most likely reveal
ataxia
hemiplegia
paraplegia
quadriplegia
rigidity
Brunner’s glands secrete an alkaline product that helps
achieve optimal pH for the activity of pancreatic enzymes. Where
are these glands located?
base of villi throughout small intestine
epithelium of Vater ampulla
jejunal submucosa and mucosa
duodenal submucosa
ileal submucosa
A 24-year-old man presents with pain in his right wrist that
resulted when he fell hard on his outstretched hand. Radiographic
studies indicate an anterior dislocation of a proximal row carpal
bone that articulates with the most lateral proximal row carpal
bone. Which of the following bones was dislocated?
capitate
lunate
scaphoid
trapezoid
triquetrum
The femoral triangle is bounded superiorly by the inguinal
ligament. Which of the following structures form the lateral and
medial borders of the femoral triangle?
Adductor longus and gracilis
adductor longus and sartorius
gracilis and pectineus
gracilis and sartorius
pectineus and sartorius
A 43-year-old woman is diagnosed with a condition that
causes excruciating pain near her nose and mouth. The involved
nerve innervates which of the following branchial arches?
1st
2nd
3rd
4th
An infant is born with an abnormally developed falciform
ligament. The hepatogastric and hepatoduodenal ligaments are
also malformed. These developmental anomalies are most likely
due to abnormal development of the
dorsal mesoduodenum
dorsal mesogastrium
pericardioperitoneal canal
pleuropericardial membranes
ventral mesentery
An autopsy is performed on a man who died of an unknown
cause. The pathologist discovers that the man has a small atrial
septal defect. The defect is seen in the portion of the atrial septum
near the upper border of the fossa ovalis. Which of the following
was the likely functional manifestation of this defect during life?
no cyanosis occurred prenatally or postnatally
postnatal cyanosis due to a shunt of blood from the left atrium to the right atrium
postnatal c. due to a shunt of blood from the right atrium to the left atrium
prenatal c. due to a shunt of blood from right atrium to left atrium
prenatal c. due to a shunt of blood from the left atrium to the right atrium
A 6-year-old boy is brought to the office for evaluation of a
neck mass. His mother reports that he first developed the mass 3
days ago, and it has not resolved. Further questioning reveals that
he has recently recovered from a viral upper respiratory infection.
He is otherwise healthy and is up to date on all recommended
vaccinations. Physical examination shows a 2-cm neck mass in
the midline immediately above the thyroid cartilage notch. The
mass elevates when he sticks his tongue out of his mouth. Which
of the following is the most likely diagnosis?
reactive lymph node
branchial cleft cyst
thyroglossal duct cyst
head and neck neoplasm
thyroid nodule
When removing an impacted mandibular third molar, the oral
surgeon must warn the patient of possible lasting numbness of the
tip of the tongue. This loss of general sensation is due to damage
to the
auriculotemporal nerve
chorda tympani
lingual nerve
mental nerve
mylohyoid nerve
A resident physician is demonstrating the correct technique
for inserting a subclavian central venous line. He has a medical
student palpate the clavicle, then the chest wall below it. The first
bony structure that can be palpated below the inferior margin of
the medial portion of the clavicle is the
acromion
atlas
first rib
manubrium
second rib
A 34-year-old woman bursts through the doors of the
emergency department. She is straining to take a breath but can
only mouth the phrase: “I can’t br—” before collapsing. She is
placed on a stretcher. Her tongue is swollen and protruding from
her mouth. The patient has only minimal air movement with bagmask
ventilation. Oxygen saturation is approximately 80%.
Attempts at oral intubation are unsuccessful due to massive soft
tissue edema of her pharynx. A decision is made to perform a
cricothyrotomy. The necessary instrument tray is collected, and
the patient’s neck is quickly prepped. After palpating the neck to
identify the appropriate landmarks, an incision should be made at
which of the following locations?
The cricothyroid membrane, which is located
at the junction of the clavicle and the
sternum
The cricothyroid membrane, which is located
between the thyroid cartilage and the cricoid
cartilage below
The thyrohyoid membrane, which is located
between the thyroid cartilage (Adam’s apple)
and the hyoid bone above
The sternal notch, which is located at the
junction of the clavicle and the sternum
The trachea, which is located below the
cricoid cartilage
An infant born to an alcoholic mother had microcephaly and
cardiac abnormalities and died despite resuscitative efforts.
During which of the following periods of pregnancy is alcohol
most teratogenic?
first 2 weeks
3rd through 9th week
9th through 12th week
12th through 16th week
16th through 20th week
A 15-year-old girl with a history of chronic rhinitis, allergy,
asthma, and nasal polyposis presents with fever and dental pain.
She is diagnosed with maxillary sinusitis. Mucopurulent exudate
would be most likely to drain through an ostium in the
bulla ethmoidalis
hiatus semilunaris
inferior nasal meatus
sphenoethmoidal recess
superior nasal meatus
A patient presents to the physician complaining of “something
wrong with her foot” that causes her to trip and fall. Physical
examination reveals an inability to dorsiflex (extend) the foot and
a loss of sensation between the first and second toes. There is no
other motor or sensory loss. Which of the following nerves was
most likely injured?
deep peroneal
femoral
sup. peroneal
sural
tibial
During a routine physical examination, a 71-year-old man is
found to have a 7-cm pulsatile mass deep in the abdomen,
between the xiphoid and the umbilicus. He has a history of
untreated hypertension. The endothelial lining of the affected
structure is composed of which of the following tissue types?
stratified cuboidal epithelium
stratified squamous epithelium
pseudostratified epithelium
simple squamous epithelium
One week following a sexual encounter at a ski resort in
Colorado, a young woman develops a painful, swollen knee joint.
The emergency department physician suspects gonococcal
arthritis and wants to confirm this by sending joint fluid for
bacterial culture. He uses the standard suprapatellar approach and
passes a needle from the lateral aspect of the thigh into the region
immediately proximal to the patella. Through which of the
following muscles does the needle pass?
adductor magnus
gracilis
iliacus
sartorius
vastus lateralis
A 67-year-old man has an abnormal neurologic exam. An
electroencephalogram is subsequently performed and reveals
delta waves over his left frontal lobe. Which of the following was
the most likely abnormal finding on his neurologic exam?
left hemiparesis
left hemisensory loss
right homonymous hemianopia
right hemiparesis
A 23-year-old woman wearing high-heeled shoes inverts and
sprains her ankle while running down a flight of stairs. Which of
the following ligaments did she most likely injure?
ant. talotibial
calcaneofibular
calcaneotibial
deltoid
med. collateral
A surgeon performing an appendectomy makes an incision
through the ventrolateral abdominal wall. The layers of the
abdominal wall are shown below.
1. Internal oblique
2. External oblique
3. Peritoneum
4. Transversus abdominis
Which of the following corresponds to the order of
penetration of the layers of the abdominal wall?
1-3-4-2
2-1-3-4
2-1-4-3
4-1-2-3
4-2-1-3
A 49-year-old woman comes to the emergency department
because of right upper quadrant pain, nausea, vomiting, and fever.
She also complains of pain in her right shoulder. A right upper
quadrant ultrasound reveals multiple gallstones and
pericholecystic fluid. Which of the following dermatomes is most
likely involved in her shoulder pain?
C1-C2
C3-C5
C6-C8
T1-T3
T4-T6
A 57-year-old man has hematuria and left-sided flank pain.
Diagnostic studies show a left-sided renal mass with extension
into the renal vein. A radical nephrectomy is performed, and the
specimen is sent for pathologic evaluation. Which of the
following structures present in this patient’s specimen is lined
with epithelium derived from mesoderm of the ureteric bud?
bowman capsule
distal convoluted tubule
loop of henle
proximal convoluted tubule
ureter
A woman comes to the physician for a prenatal visit.
Examination reveals that her uterus is considerably larger than her
gestational age would predict. An ultrasound examination is
ordered and reveals that she has polyhydramnios. Which of the
following congenital defects of the fetus would be most likely to
be associated with this abnormality?
atrial septal defect
esophageal atresia
lung hypoplasia
meckel diverticulum
renal agenesis
A gastric biopsy is performed on a 42-year-old man. As the
pathologist inspects the specimen, he observes numerous, normal
cuboidal-to-columnar cells with apical membrane-bound
secretion granules in the gastric glands. From which area of the
stomach was the biopsy specimen most likely taken?
cardiac region
columns of morgagni
fundic region
greater omentum
pyloric region
During a football game, a player sustains a powerful blow to
the lateral side of his weight-bearing leg. He experiences
excruciating knee pain and is unable to walk. The three structures
most likely to be injured are the
anterior cruciate and lat. collateral ligg and the lat. meniscus
ant. cruciate and med. collat. ligg and medial meniscus
post. cruciate and lat. collat. ligg and lateral menisucs
post. cruciate and med. collat. ligg and lateral meniscus
post. cruciate and med. collat. ligg and med. meniscus
A mother brings her 5-year-old daughter to the physician
complaining that the child still seems to regularly wet herself
despite having been toilet-trained. The physician orders an IV
pyelogram, which demonstrates a complete duplication of the
ureter on the right side. Although one ureter opens normally into
the bladder, the other opens ectopically into the vagina. This
congenital anomaly is caused by
duplication of prox. mesonephric (Wolffian) duct
early division of ureteric bud
etopic growth of pronephros
improper unio of excretory tubules and collecting tubules
persistence of embryonic ureters as kidney ascends from pelvis to superior abdomen
A newborn baby is observed to be cyanotic immediately after
birth. Diagnostic studies, including an ultrasound, reveal that the
baby has persistent truncus arteriosus. Which of the following
additional defects is this baby most likely to have?
dextrocardia
membranous ventricular septal defect
secundum-type atrial septal defect
tetralogy of fallot
transposition of great arteries
A 61-year-old woman undergoes surgery to remove a solitary
painless mass just anterior to the tragus of her left ear. Pathologic
examination shows a wellcircumscribed, yellowish-white tumor
with a proliferation of epithelial and myoepithelial cells in duct
formations within a background of loose myxoid tissue. During
the surgery, particular attention is paid to the nerve that exits the
skull via the stylomastoid foramen, passes lateral to the styloid
process, and then enters this affected structure. Injury to the lower
division of this nerve during surgery will most likely result in
inability to furrow the brow (to frown) on the same side
numbness over angle and mental region of jaw on same side
ptosis of eye on same side
weakness in closing eye on same side
weakness of lower lip on same side
An arteriogram is performed on a patient with atherosclerosis.
Luminal narrowing of which of the following vessels would
compromise blood flow through the renal arteries?
abd. aorta
celiac trunk
common iliac A
inf. mesenteric A
sup. mesenteric A
Nissl bodies correspond to which of the following cytoplasmic organelles?
Golgi apparatus
mitochondria
nucleoli
rough ER
Smooth ER
A 42-year-old man undergoes surgery for medullary
carcinoma of the thyroid. After the surgery, he complains of a
“noisy quality” to his voice. This condition was most likely
caused by damage to the
int. laryngeal nerve
recurrent laryngeal n
thyroarytenoid muscle
vestibular folds
vocal folds
After an amniocentesis, a 29-year-old woman who is carrying
twins learns that one fetus has XY chromosomes and the other
has XX chromosomes. At 37 weeks’ gestation, the woman
delivers two healthy babies. Which of the following structures is
likely to be present in the baby with the XY chromosomes but not
in the one with XX chromosomes?
bulbospongiosus muscle
bulbourethral gland
corpus cavernosum
membranous urethra
perineal body
During an automobile accident, a person sustains a “broken
neck” and dies after a small bony fragment is driven into his
spinal cord. From which of the following bones was this fragment
most likely derived?
atlas
axis
7th cervical vertebrae
6th cervical vertebrae
5th cervical vertebrae
A patient is complaining of difficulty swallowing. A barium
contrast x-ray shows a constriction of the esophagus at the level
of the third thoracic vertebra. An aortogram shows that the patient
has a double aortic arch. Which of the following developmental
abnormalities explains this finding?
Abnormal persistence of the right dorsal aorta
Abnormal persistence of the right fourth
aortic arch
Abnormal persistence of the right seventh
inter-segmental artery
Abnormal persistence of the right sixth aortic
arch
Abnormal persistence of the right third aortic
arch
Because she is too weak to go to the cafeteria, a 93-year-old
nursing-home resident on a liquid diet is fed in bed. She refuses to
sit up, so the aide has to feed her while she is lying on her back.
Halfway through the feeding, the patient aspirates the liquid and
subsequently develops pneumonia. Which of the following is the
most likely site of this pneumonia?
Anterior segment of the right upper lobe
Apical segment of the right lower lobe
Inferior lingular segment of the left upper
lobe
Lateral segment of the right middle lobe
Superior lingular segment of the left upper
lobe
A patient has a tiny (0.2 cm) but exquisitely painful tumor
under the nail of her index finger. Local anesthetic block to a
branch of which of the following nerves would be most likely to
provide adequate anesthesia for the surgical removal of the mass?
axillary
median
musculocutaneous
radial
ulnar
A 3-year-old boy has repeated episodes of sore throat and
fever. He undergoes surgery to remove collections of lymphoid
tissue that lie on each side of the oropharynx between the
palatoglossal and palatopharyngeal arches. The removed
structures developed from which of the following pharyngeal
pouches?
1st
2nd
3rd
4th
5th
A 35-year-old woman with severe dysmenorrhea and
prolonged menstrual periods due to large uterine fibroids
undergoes a hysterectomy. Which of the following structures is
the gynecologist most likely to inadvertently ligate during
surgery?
int. iliac A
int. iliac V
ovarian A
ureter
uterine V
A pregnant woman comes to her physician with questions
about the effect that ingested substances may have on her unborn
child. The physician explains that large molecules do not pass
between the mother and fetus because of the placental barrier. The
physician adds that fetal blood is in the fetal blood vessels of the
villi of the placenta and the mother’s blood is in the maternal
blood vessels, and that these blood vessels do not connect. The
placental villi are formed from which of the following cells?
Cytotrophoblast
Embryoblast
Endometrium
Epiblast
Syncytiotrophoblast
A 32-year-old man complains of progressive, severe,
generalized headaches that began 3 months ago, are worse in the
mornings, and lately have been accompanied by projectile
vomiting. He has also lost his upper gaze, and on physical
examination the upper part of the sclera is visible above the
downward looking irises. Which of the following is the most
likely diagnosis?
Brain tumor affecting the frontal lobe
Nelson syndrome
Pituitary apoplexy
Posterior fossa tumor
Tumor in the area of the pineal gland
A prostate-specific antigen (PSA) level is drawn from a 54-
year-old man as part of a routine health evaluation. Which of the
following embryonic structures gives rise to the organ being
screened for carcinoma?
genital tubercle
processus vaginalis
testis cords
tunica albuginea
urogenital sinus
A football player is examined by the team physician following
a shoulder injury during a game. Preliminary x-ray films show an
inferior dislocation of the humerus. On further examination, there
is weakness in lateral rotation and abduction of the arm. The
nerve most likely affected is the
axillary
dorsal scapular
radial
suprascapular
thoracodorsal
During anatomy laboratory, a first-year medical student is
dissecting the atrial chambers of the heart. At the upper border of
the fossa ovalis, she discovers a small opening through which the
tip of her probe can be passed from the right into the left atrium.
The laboratory instructor identifies this as a probe patency of the
atrial septum. This probe patency resulted from which of the
following developmental events?
Excessive resorption of the septum primum
Failure of the endocardial cushions to form
Failure of postnatal fusion of septum primum
and septum secundum
Failure of the right and left conotruncal
ridges to fuse
Failure of the septum primum to fuse with the
endocardial cushions
A 20-year-old man is stabbed immediately to the left of the
body of the sternum at the fifth intercostal space. The knife most
likely penetrated the
left atrium
left ventricle
right atrium
right ventricle
stomach
A 5-month old girl has fatigue on exertion. She was born at
full-term with a birth weight of 9 lb and had an uncomplicated
perinatal period. She has been bottlefed, and there have been no
feeding problems. She is alert and appears well. Physical
examination reveals a loud holosystolic murmur in the left
parasternal region with an associated systolic thrill. The first and
second heart sounds are normal. There is no gallop or diastolic
murmur. Her blood pressure is normal in all four extremities, and
she has palpable peripheral pulses. There is no peripheral edema
or cyanosis. Which of the following is the most likely diagnosis?
Atrial septal defect
Patent ductus arteriosus
Patent foramen ovale
Pulmonic stenosis
Ventricular septal defect
An elderly woman with osteoporosis is taken to the
emergency department following a fall. One of her legs appears
shortened and is externally rotated. A fracture of which part of the
femur is suggested by these findings?
greater trochanter
lat. epicondyle
med. epicondyle
neck
shaft
An otherwise healthy first-year medical student visits the
student health office for a physical examination. He is taking no
medications. He is concerned because he has noticed several
painless uniform “large bumps” at the back of his tongue. These
are most likely
aphthous ulcers
candida colonies
circumvallate papillae
filiform papillae
fungiform papillae
An oblique x-ray view of a patient with right middle lobar
pneumonia demonstrates an area of consolidation bounded by
sharp, intersecting, relatively straight lines above and below.
These lines correspond to which of the following?
Diaphragm above and oblique fissure below
Oblique fissure above and breast shadow
below
Oblique fissure above and transverse fissure
below
Transverse fissure above and diaphragm
below
Transverse fissure above and oblique fissure
below
During an interview, a 34-year-old psychiatric patient
suddenly becomes aggressive. The patient is quickly taken to a
quiet, private room and given an intramuscular injection of
haloperidol in the upper outer quadrant of the buttock. The
injection is given at this specific location to prevent damage to
which of the following nerves?
common peroneal
lat. fem. cutaneous
obturator
sciatic
sup. gluteal
A 21-year-old man is brought to the hospital by emergency
medical technicians after he was involved in a car accident.
Examination reveals a clear fluid draining from his left ear.
Laboratory studies confirm that the fluid is cerebrospinal fluid.
Which of the following is the most likely site of trauma that has
resulted in the leakage of this fluid?
Fracture in the region of the internal auditory
meatus, along with rupture of the tympanic
membrane
Fracture in the region of the jugular foramen,
along with rupture of the tympanic
membrane
Fracture of the external ear canal, along with
rupture of the tympanic membrane
Fracture of the floor of the anterior cranial
fossa, along with rupture of the tympanic
membrane
Fracture of the floor of the middle cranial
fossa, along with rupture of the tympanic
membrane
During a bar fight, a 20-year-old man is stabbed with an ice
pick. The weapon passes through the superior orbital fissure.
Which of the following is most likely to be severed as the ice pick
passes through this fissure?
abducens nerve
mandibular nerve
facial nerve
ophthalmic artery
optic nerve
A patient presents to the emergency department after
sustaining a laceration of the first web space of his hand in a rockclimbing
accident. Which of the following structures is also likely
to be injured?
deep branch of radial nerve
Opponens pollicis
Radial A
Recurrent branch of median nerve
Superficial palmar arch
After a motor vehicle accident, a patient is brought to the
emergency room. X-rays reveal that she has fractures of her left
ninth and tenth ribs. She has a rapid heart rate and low blood
pressure. Peritoneal lavage reveals free blood in the peritoneal
cavity. A surgeon is able to stop the bleeding by placing a clamp
across which of the following structures?
broad ligament
falciform ligament
gastrosplenic ligament
hepatoduodenal ligament
splenorenal ligament
A football player experiences an anterior dislocation of the
shoulder. Cutaneous sensation over the lower half of the deltoid
muscle is impaired. These findings suggest damage to which of
the following nerves?
axillary
median
radial
ulnar
musculocutaneous
A 45-year-old garbage collector has severe neck pain and
weakness in his left upper extremity. He has gotten no relief from
over-the-counter medications. He denies any history of trauma.
On examination the patient is thin and walks with his neck tilted
to the left side. The patient has limited neck flexion and extension
secondary to pain. The patient has a normal motor and sensory
examination of all extremities, with the exception of the left upper
extremity. His left radial forearm and thumb are numb to the
touch (decreased sensation to light touch). The patient has a
decreased brachioradialis reflex and slight weakness of his wrist
extensors. Plain radiographs appear normal. Which of the
following is the most likely diagnosis?
compression of left C6 nerve root
compression of left thoracic first nerve root (T1)
compression of right T1 nerve root
tumor in lumbar spine
tumor in sacral spine
A patient with a left adrenal mass is scheduled for surgery.
The surgeon is planning to approach the suprarenal area by
removing the twelfth rib. With this approach, the surgeon should
take particular care to avoid damaging which of the following
structures?
aorta
diaphragm
pancreas
stomach
vena cava
A 45-year-old man has an obvious mass on the right side of
his face. It is determined that he has a benign tumor of the parotid
gland, and the tumor is excised. After surgical excision of the
tumor, it is noted that the patient’s mouth droops on the right side
and, when asked to smile, his smile is asymmetrical. The patient
is able to open and close both eyes normally and can wrinkle his
forehead symmetrically and raise both eyebrows. Sensation is
normal on both sides of his face. Which of the following is the
most likely cause of the findings?
Damage to branches of mental nerve
damage to branches of infraorbital nerve
damage to branches of facial nerve
damage to branches of glossopharyngeal nerve
damage to branches of hypoglossal nerve
During anatomy lab, a medical student notes a fibrous band
that runs on the visceral surface of the liver. It is attached on one
end to the inferior vena cava and on the other end to the left
branch of the portal vein. In the embryo, this structure
corresponds to the
ductus venosus
ligamentum teres
ligamentum venosum
umbilical Aa
umbilical V
While examining a newborn baby in the nursery, a physician
notes that urine is draining from the umbilicus. Contrast dye is
introduced into the bladder through the urethra, and it is
confirmed radiologically that dye is passing to the umbilicus.
Which of the following embryonic structures has abnormally
persisted in this patient?
allantoic duct
mesonephric duct
mesonephric tubules
ureteric bud
urorectal septum
A 4-year-old boy with recurrent urinary tract infections is
evaluated for renal/urinary tract abnormalities with a voiding
cystourethrogram (VCUG). Reflux is discovered, so an
intravenous pyelogram (IVP) is performed. The renal anatomy
appears normal. On the IVP, which of the following structures
would have been seen emptying into the renal pelvis?
major calyx
minor calyx
renal pyramid
ureter
A neonate is observed to have a small notch in the transitional
zone and a vermillion border of the lip. Which of the following is
the most likely etiology of this malformation?
Abnormal development of the third and
fourth pharyngeal pouches
Bony defects of the malar bone and mandible
Failure of the maxillary processes and medial
nasal swellings to fuse
Incomplete joining of the palatine shelves
Insufficient migration of neural crest cells
A patient’s left hypoglossal nerve (CN XII) is injured during a
carotid endarterectomy. Which of the following would most likely
result from this injury?
Decreased gag reflex on the left
Decreased salivation from the left
submandibular and sublingual salivary
glands
Deviation of the tongue to the left on
protrusion
Inability to elevate the pharynx on the left
during swallowing
Inability to perceive sweet and salt taste
sensation on the anterior part of the left side
of the tongue
During a physical examination a physician elicits a pupillary
light reflex by shining a light into a patient’s eye. The iris
contracts, thereby constricting the pupil. Where are the cell bodies
of the preganglionic neurons found that are responsible for this
response?
oculomotor nucleus
Edinger-Westphal Ncl
Ciliary ganglion
precentral gyrus
geniculate ganglion
A 69-year-old woman fractures her humerus during a motor
vehicle accident. Which of these types of bone will most likely be
seen in a biopsy taken from the healing area?
cancellous
compact
spongy
trabecular
woven
A 58-year-old man with lymphoma has shortness of breath
and chest pain. A chest x-ray shows bilateral blunting of the
costophrenic angle. A thoracocentesis is performed. During this
procedure, it is important to pass the needle immediately above
the rib to prevent damage to which of the following structures in
the subcostal groove?
intercostal AV
intercostal N
intercostal NA
intercostal NV
intercostal NAV
A newborn boy does not pass meconium until 48 hours after
his birth. Several weeks later his mother complains that he has not
been passing stool regularly. Anorectal manometry reveals
increased internal anal sphincter pressure on rectal distention with
a balloon. The patient’s disorder may be attributed to
defective recanalization of the colon
failure of neural crest cells to migrate into the
colonic wall
herniation of abdominal contents into the
umbilical cord
persistence of the proximal end of the yolk
stalk
presence of a rectourinary fistula
A 38-year-old woman slips on an icy sidewalk and falls,
hitting the ground with her right elbow. She reports that she is
experiencing severe pain in her upper limb. Examination reveals
that she cannot extend her hand at the wrist. She has diminished
sensation on the lateral portion of the dorsum of her hand. Which
of the following is the most likely site of her fracture?
scaphoid
distal end of radiius
medial epicondyle of humerus
midportion of humerus shaft
surgical neck of humerus
An infant is brought to the emergency department with a
temperature of 40° C (104° F). The physician notes that the infant
has a “bulging anterior fontanelle.” The third-year medical
student reads the physician’s note and wants to evaluate this
physical finding, but she forgot where the anterior fontanelle is. In
evaluating this finding, the medical student should look for which
of the following anatomic landmarks?
bregma
coronal suture
lambda
pterion
sagittal suture
A 63-year-old man has blood-streaked stools and constipation.
Barium enema shows a right-sided obstructing lesion. Surgery is
performed, and pathologic evaluation reveals a welldifferentiated,
colonic adenocarcinoma. Observation of a
hematoxylin and eosin-stained microscopic slide from the
specimen reveals that the nuclei of the cells are blue. What is the
basis for this observation?
eosin binds to carbohydrates
eosin binds to lipids
eosin binds to nucleic acids
hematoxylin binds to lipids
hematoxylin binds to nucleic acids
On physical examination, the upper body of a 7-year-old boy
appears much more developed than his lower body. Blood
pressure in the upper extremities exceeds that of the lower
extremities. On cardiac examination, there is a midsystolic
murmur over the anterior chest and back. The child’s lower
extremities are cold, and femoral pulses are absent. The part of
the vascular system that is affected in this disorder is derived
from which of the following embryologic structures?
3rd, 4th and 6th aortic arches
bulbus cordis
ductus arteriosus
left horn of sinus venosus
right common cardinal vein
A urologist performs a cystoscopy to examine the bladder and
the openings of the ureters into the bladder. After distention of the
bladder with air, the physician slowly passes the cystoscope up
the urethra into the bladder. In which direction should she turn the
head of the cystoscope to see the ureteric orifices and examine for
blockage?
ant + inf
ant + sup
post + inf
post + sup
After receiving a punch to the left eye, a 16-year-old boy
complains of double vision. During clinical testing, he has
difficulty when asked to look medially, inferolaterally,
superolaterally, and superomedially. The affected muscles are
derived from which of the following structures?
branchial arches
optic cup ectoderm
somites
somitomeres
splanchnic mesoderm
Which of the following structures constitutes part of
the ventricles of the heart?
auricle
crista terminalis
fossa ovalis
sinus venarum
trabeculae carnae
the nucleus that lies immediately medial (and deep) to the uncus is the
amygdala
caudate nucleus
claustrum
hippocampus
putamen
which of the following is a derivative of second pharyngeal arch?
eustachian tube
ext. auditory meatus
palatine tonsil
stylohyoid muscle
tensor tympani
which of the following renal structures is most medially located?
major calyx
minor calyx
renal cortex
renal pelvis
renal pyramid
Which of the following veins empties into the left renal vein?
hepatic
left suprarenal
right gonadal
right renal
an infant is born with an abnormally developed falciform ligament. the hepatogastric and hepatoduodenal ligaments are also malformed. these developmental anomalies are most likely due to abnormal development of the
dorsal mesoduodenum
dorsal mesogastrium
pericardioperitoneal canal
pleuropericardial membranes
ventral mesentery
The interlobular arteries of the kidney result from subdivision of the
afferent arterioles
arcuate arteries
interlobar arteries
renal artery
the septum transversum in the fetus gives rise to which of the following adult structures?
bare area of liver
central tendon of diaphragm
fibrous pericardium
greater omentum
ligamentum venosum
the primordium of the respiratory system that forms the internal epithelial lining of the trachea, bronchi, and lungs is derived entirely from which of the following embryologic entities?
foregut endoderm
midgut endoderm
splanchnic mesoderm
stomodeum
both endoderm and mesoderm
the endothelial lining of the aorta is composed of which of the following tissue types?
pseudostratified epithelium
simple columnar epithelium
simple cuboidal epithelium
simple squamous epithelium
stratified columnar epithelium
a patient with acute cholecystitis experiences referred pain to the right shoulder. which of the following dermatomes is most likely involved?
C1-C2
C3-C5
C6-C8
T1-T3
T4-T6
which of the following embryonic structures gives rise to the adrenal cortex?
ectoderm
endoderm
mesoderm
mesonephros
neural crest cells
which of the following is the embryologic precursor of the fibrous remnant that runs in a fissure on the visceral surface of the liver?
ductus arteriosus
ductus venosus
hepatic portal vein
vitelline vein
left umbilical artery
following thyroidectomy, hoarseness of the voice may occur. this condition is caused by damage to the
int. laryngeal nerve
recurrent laryngeal nerve
thyroarytenoid muscle
vestibular folds
which of the following pharyngeal pouches develops into the palatine tonsil?
1st
2nd
3rd
4th
5th
a 35yo woman with severe dysmenorrhea and prolonged menstrual periods due to large uterine fibroids undergoes a hysterectomy. which of the following structures is the gynecologist most likely to inadvertently ligate during surgery?
internal iliac A
internal iliac V
ovarian A
ureter
uterine V
which of the following structure does the fetal allantoic duct become in the adult?
cloaca
urachus
ureter
urethra
medial umbilical ligament
most afferents to the cerebral cortex derive from the
basal ganglia
cerebral cortex
hippocampus
spinal cord
thalamus
which of the following fibers provide the only output from the cerebellar cortex?
climbing
golgi cell
granule cell
purkinje
parallel
early degeneration of the ureteric bud results in which of the following congenital renal abnormalities?
double ureter
patent urachus
horseshoe kidney
renal cysts
renal agenesis
the hippocampus projects to the mammillary bodies via which of the following structures?
ant. commissure
post. commissure
corpus callosum
fornix
diagonal band
the intraembryonic mesoderm is formed during the 3rd week of embryonic life is principally derived from
epiblast
yolk sac
primitive node
definitive ectoderm
definitive endoderm
which of the following prevents hyperextension of the knee?
ant. cruciate lig.
lat. semilunar cartilage
med. semilunar cart.
post. cruciate lig.
transverse lig.
which of the following hormones is secreted by ant. pituitary cells that stain with acidic dyes?
ACTH
FSH
LH
TSH
prolactin
a neonate is observed to have a cleft lip. which of the following is the most likely etiology of this malformation?
abnormal development of 3rd and 4th pharyngeal pouces
bony defects of malar bone and mandible
failure of maxillary processes and medial nasal swellings to fuse
incomplete joining of the palatine shelves
insufficient migration of neural crest cells
incomplete fusion of the embryonic endocardial cushions can produce which of the following congenital defects?
atrioventricular septal defect
coarctation of the aorta
pulmonary stenosis
tetralogy of fallot
transposition of the great vessels
a newborn boy does not pass meconium until 48 hours after his birth. several weeks later his mother complains that he has not been passing stool regularly. anorectal manometry reveals increased internal anal sphincter pressure on rectal distention with a balloon.the patient's disorder may be attributed to
defective recanalization of the colon
failure of neural crest cells to migrate into the colonic wall
herniation of abd. contents into the umbilical cord
persistence of the prox. end of yolk stalk
presence of a rectourinary fistula
a blockage of the cerebral aqueduct will produce an increase in pressure initially in the
magendi foramen
luschka foramina
4th ventricle
3rd ventricle
