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Worksheets

Units 4 and 5 Test

Total questions: 94

Worksheet time: 47mins

Name
Class
Date
1.

Phase of mitosis where nucleolus and nuclear envelope disappear, chromosomes condense, centrioles migrate to poles and the spindle begins to form

a)

prophase

b)

metaphase

c)

anaphase

d)

telophase

2.

Phase of mitosis where chromosomes line up at the metaphase plate in the center of the cell and attached to the spindle fibers.

a)

prophase

b)

metaphase

c)

anaphase

d)

telophase

3.

Phase of mitosis where nucleolus and nuclear envelope reappear, chromosomes decondense, the spindle breaks down, cytokinesis begins

a)

prophase

b)

metaphase

c)

anaphase

d)

telophase

4.

Phase of mitosis where sister chromatids (copies of the same chromosome) separate and are pulled to opposite poles by shortening spindle fibers.

a)

prophase

b)

metaphase

c)

anaphase

d)

telophase

5.

Process that includes a single nuclear division and yields two identical nuclei in daughter cells

a)

mitosis

b)

meiosis

c)

apoptosis

d)

cirrhosis

6.

period of non division where a cell is preparing to divide

a)

interphase

b)

mitosis

c)

cytokinesis

d)

M phase

7.

Correct order of cell cycle phases

a)

G1, S, G2, Mitosis, Cytokinesis

b)

G1, G2, S, Mitosis, Cytokinesis

c)

Mitosis, G1, S, G2, Cytokinesis

d)

S, G1, G2, Cytokinesis, Mitosis

8.

Phase of interphase where the DNA is replicated

a)

S phase

b)

G1 phase

c)

G2 phase

d)

cytokinesis

9.

phase that cells typically spend the most amount of time in

a)

interphase

b)

mitosis

c)

cytokinesis

10.

When a cell emits a signaling molecule meant for itself

a)

autocrine

b)

juxtacrine

c)

paracrine

d)

endocrine

11.

When a cell emits a signaling molecule meant for a cell it is in direct contact with

a)

autocrine

b)

juxtacrine

c)

paracrine

d)

endocrine

12.

When a cell emits a signaling molecule meant for another cell that is only a short distance away

a)

autocrine

b)

juxtacrine

c)

paracrine

d)

endocrine

13.

When a cell emits a signaling molecule meant for another cell that is a long distance away, uses hormones as signaling molecules and bloodstream for transport

a)

autocrine

b)

juxtacrine

c)

paracrine

d)

endocrine

14.

What is the correct order for the events in a signaling pathway?

a)

reception, transduction, cellular response

b)

reception, cellular response, transduction

c)

transduction, reception, cellular response

d)

transduction, cellular response, reception

15.

Which of the following describes how bacteria are able to determine the density of the bacterial population around them through signaling molecules in an attempt to coordinate their activities

a)

quorum sensing

b)

apoptosis

c)

synergism

d)

negative feedback

16.

This is a protein hormone produced by the pancreas that acts a ligand to decrease blood glucose by binding receptors on cell surfaces, triggering glucose uptake by the cells

a)

insulin

b)

acetylcholine

c)

aldosterone

d)

thyroxine

17.

This is a steroid hormone produced by the adrenal gland that acts a ligand to increase blood volume by binding receptors in kidney cells, triggering water and sodium retention

a)

insulin

b)

acetylcholine

c)

aldosterone

d)

thyroxine

18.

This is a neurotransmitter that triggers muscle contraction. It is usually quickly broken down by acetylcholinesterase.

a)

acetylcholine

b)

aldosterone

c)

insulin

d)

epinephrine

19.

Which of the following produce proteins that would normally act to inhibit cell cycle progression if DNA were to be damaged?

a)

tumor suppressor genes

b)

protooncogenes

c)

oncogenes

d)

SRY genes

20.

Which of the following produce proteins that would normally act to stimulate cell cycle progression ?

a)

tumor suppressor genes

b)

protooncogenes

c)

p53

d)

SRY genes

21.

Which of the following is an example of a tumor suppressor gene that is commonly mutated in individuals with cancer?

a)

p53

b)

SRY

c)

TSH

22.

Which of the following is defined as uncontrolled cell growth and division?

a)

cancer

b)

apoptosis

c)

mitosis

d)

endometriosis

23.

Cells produced by mitosis are

a)

haploid

b)

diploid

c)

triploid

d)

polyploid

24.

What happens to the amount of DNA in the parent cell after replication occurs during the S phase of interphase?

a)

it doubles

b)

it is reduced by half

c)

it remains the same

25.

What would be the result if cytokinesis failed?

a)

a single cell with two identical nuclei

b)

two cells with identical nuclei

c)

two cells that have half the number of chromosomes as the original cell

d)

a single cell with one large nucleus and 2 times the number of chromosomes

26.

What would be the result if the cell cycle proceeded even if not all of the chromosomes were attached to spindle fibers?

a)

daughter nuclei would have extra or missing chromosomes

b)

daughter nuclei would be identical

c)

only one large nucleus would form

d)

the mitotic spindle would not break down

27.

If a cell is healthy and it cannot correct DNA damage, what will occur?

a)

the cell will undergo apoptosis

b)

the cell will continue to divide

28.

Which is true of cyclins?

a)

cyclins are always present at the same concentration inside a cell

b)

cyclins are produced and degraded to control progression through the cell cycle

29.

Which is true of cyclin-dependent kinases (cdks)?

a)

they are always present inside of the cell in the same concentrations, but are only active when bound to their respective cyclins

b)

they are produced and degraded to control progression through the cell cycle

30.

Nerve cells use neurotransmitters to send signals to other nearby nerve cells

a)

paracrine

b)

endocrine

c)

juxtacrine

d)

autocrine

31.

Which signaling molecules are most likely to have receptors in the cytoplasm or on the nuclear membrane?

a)

steroid hormones

b)

protein hormones

c)

large polar molecules

d)

charged ions

32.

Which signaling molecules are most likely to have receptors in the cytoplasm or on the nuclear membrane?

a)

small nonpolar molecules

b)

protein hormones

c)

large polar molecules

d)

charged ions

33.

Which signaling molecules are most likely to have receptors on the cell membrane surface?

a)

small nonpolar molecules

b)

protein hormones

c)

steroid hormones

34.

Which signaling molecules are most likely to have receptors on the cell membrane surface?

a)

small nonpolar molecules

b)

large polar molecules

c)

steroid hormones

35.

Which of the following is the function of mitosis in unicellular eukaryotes, like an amoeba?

a)

asexual reproduction

b)

tissue repair

c)

organisms growth

36.

Which of the following is the function of mitosis in multicellular eukaryotes?

a)

asexual reproduction

b)

growth and tissue repair

37.

Which correctly describes mitosis in multicellular eukaryotes?

a)

occurs in somatic cells to produce two identical diploid cells

b)

occurs in somatic cells to produce four identical diploid cells

c)

occurs in gonadal cells to produce two identical diploid cells

d)

occurs in gonadal cells to produce four identical diploid cells

38.

The M checkpoint looks for...

a)

attachment of chromosomes to spindle fibers prior to anaphase

b)

correct and complete replication of chromosomes prior to mitosis

c)

cell size, nutrient availability, growth factors and DNA damage prior to S phase

39.

The G1 checkpoint looks for...

a)

attachment of chromosomes to spindle fibers prior to anaphase

b)

correct and complete replication of chromosomes prior to mitosis

c)

cell size, nutrient availability, growth factors and DNA damage prior to S phase

40.

The G2 checkpoint looks for...

a)

attachment of chromosomes to spindle fibers prior to anaphase

b)

correct and complete replication of chromosomes prior to mitosis

c)

cell size, nutrient availability, growth factors and DNA damage prior to S phase

41.

The function of a kinase is ...

a)

to phosphorylate a molecule (often the next enzyme in a transduction pathway, which alters its shape, activating it)

b)

to dephosphorylate a molecule (often the next enzyme in a transduction pathway, which alters its shape, deactivating it)

c)

to bind ligand-gated ion channel receptors, allowing ion flow

d)

to bind ligand-gated ion channels, preventing ion flow

42.

Which term describes the asexual reproduction of unicellular organisms, which involves mitosis in eukaryotes (amoeba, paramecium, etc)?

a)

binary fission

b)

reception

c)

synthesis

d)

propogation

43.

Which describes cytokinesis?

a)

division of the cytoplasm between daughter cells at the end of the cell cycle

b)

separation of sister chromatids during anaphase

c)

the condensation of chromosomes during prophase

d)

programmed cell death in response to DNA damage

44.

Which describes an exit from the cell cycle, where the cell no longer divides unless stimulated to do so?

a)

G0

b)

G1

c)

G2

d)

S

45.

epinephrine is a protein hormone produced by the adrenal gland, upon binding its receptor, it triggers the breakdown of glycogen into glucose for cellular respiration to produce ATP. This is a form of...

a)

endocrine signaling

b)

paracrine signaling

c)

autocrine signaling

d)

juxtacrine signaling

46.

Cyclic AMP, or cAMP, is a secondary messenger that is used in many transduction pathways. Secondary messengers are important when...

a)

ligands cannot enter the cell and have cell surface receptors

b)

ligands can enter the cell and have intracellular receptors

47.

There are two different sexes of yeast cells, they release signaling molecules that bind to receptors on the cell surface of the opposite sex. The binding of the ligand to the receptor eventually leads to which cellular response?

a)

genes for mating to be turned on

b)

genes for lactose breakdown to be turned on

c)

the uptake of glucose from the bloodstream

d)

the release of epinephrine neurotransmitters

48.

Morphogens are chemical signals released during embryonic development, they emanate from a restricted region of a tissue and spread away from their source to form a concentration gradient that will determine the fate of each cell. Because the embryo is small, these cells are located short distances from each other. This is an example of ...

a)

paracrine signaling

b)

endocrine signaling

c)

juxtacrine signaling

d)

autocrine signaling

49.

The activation of which gene leads to the production of testosterone and development of male genitalia during fetal development?

a)

SRY

b)

X

c)

G

d)

p53

50.

This is a protein hormone responsible for the breakdown of glycogen in cells to prepare for fight or flight response.

a)

acetylcholine

b)

aldosterone

c)

insulin

d)

epinephrine

51.

Plasmodesmata are channels that connect the cytoplasm of adjacent plant cells, allowing the passage of small molecules. This is an example of..

a)

autocrine signaling

b)

paracrine signaling

c)

endocrine signaling

d)

juxtacrine signaling

52.

Amplification of a signal describes...

a)

termination after the cellular response occurs

b)

an increased number of molecules being activated at each step in the transduction pathway

c)

the binding of a ligand to its receptor

d)

steroid hormones binding intracellular receptors in the cytoplasm

53.

Which disease results in limited or no production of insulin, leaving individuals unable to regulate blood glucose levels?

a)

type I diabetes

b)

hypthyroidism

c)

cystic fibrosis

d)

alzheimers

54.

The nerve gas sarin acts as a noncompetitive inhibitor for the enzyme acetylcholinesterase. How does this affect acetylcholine that triggers muscle contraction?

a)

acetylcholinesterase will be unable to breakdown acetylcholine, and the muscles will continue to contract

b)

there will be no change in the function of acetylcholinesterase

55.

positive feedback describes...

a)

when a perturbance causes the system to move further from the set point in the direction of the perturbance until system change is achieved, homeostasis is not restored

b)

when the system moves back to the set point in response to the perturbance, homeostasis is restored

56.

negative feedback describes...

a)

when a perturbance causes the system to move further from the set point in the direction of the perturbance until system change is achieved, homeostasis is not restored

b)

when the system moves back to the set point in response to perturbance, homeostasis is restored

57.

Many signaling molecules, receptors and pathways are similar in all living organisms. This suggests...

a)

the organisms all share a common ancestor that passed down effective signaling mechanisms

b)

all organisms evolved their own signaling pathways separately

c)

the pathways that were passed down are highly conserved because they were not effective

58.

The image above shows...

a)

crossing over that occurs during prophase I

b)

crossing over that occurs during prophase II

c)

independent assortment during metaphase I

d)

segregation of chromosomes during anaphase I

59.

what is the expected phenotypic ratio from a cross between two individuals heterozygous for a single trait?

a)

3:1

b)

1:1

c)

1:3

d)

4:0

60.

what phenotypic ratio is expected from a cross between two individuals heterozygous for two traits?

a)

9:3:3:1

b)

1:1:1:1

c)

2:2:2:6

d)

1:2:3:6

61.

Where do males inherit x-linked traits from?

a)

mother

b)

father

c)

sister

d)

aunt

62.

What caused the chromosomal anomaly in the karyotype?

a)

nondisjunction during meiosis

b)

mutation during meiosis

c)

error in replication during interphase

d)

incomplete cytokinesis

63.

Which best explains the inheritance of mitochondrial and chloroplast DNA?

a)

they are both inherited from the ovule in plants

b)

they are both inherited from the pollen and plants

c)

the mitochondrial and chloroplast DNA in offspring are a combination of DNA from the ovule and pollen

64.

What type of inheritance is shown in the pedigree?

a)

autosomal recessive

b)

x-linked recessive

c)

autosomal dominant

d)

mitochondrial

65.

What type of inheritance is shown by the pedigree?

a)

x-linked recessive

b)

autosomal recessive

c)

autosomal dominant

d)

mitochondrial

66.

What type of inheritance is shown by the pedigree?

a)

x-linked recessive

b)

autosomal recessive

c)

autosomal dominant

d)

mitochondrial

67.

What type of inheritance is shown by the pedigree?

a)

x-linked dominant

b)

autosomal recessive

c)

autosomal dominant

d)

mitochondrial

68.

What type of inheritance is shown by the pedigree?

a)

x-linked dominant

b)

autosomal recessive

c)

autosomal dominant

d)

mitochondrial

69.

Looking at the image, which answer correctly describes the chromosome number throughout meiosis?

a)

2n, 2n, 2n, n

b)

n, 2n, n, 1/2 n

c)

n, 2n, n, n

d)

2n, 2n, n, n

70.

If you want to know the probability of event A AND event B occurring at the same time...

a)

multiply the probability of event A and event B

b)

divide the probability of event A and event B

c)

subtract the probability of event A and event B

d)

add the probability of event A and event B

71.

If you want to know the probability of event A OR event B occurring ...

a)

multiply the probability of event A and event B

b)

divide the probability of event A and event B

c)

subtract the probability of event A and event B

d)

add the probability of event A and event B

72.

What degrees of freedom would you use for the following chi-square set up?

a)

3

b)

2

c)

1

d)

4

73.

If your chi-square value is less than the critical value...

a)

fail to reject null

b)

reject null

74.

If your chi-square value is greater than the critical value...

a)

fail to reject null

b)

reject null

75.

Which offspring are recombinant?

a)

gray normal, black vestigial

b)

gray normal, gray vestigial

c)

gray vestigial, black normal

d)

black vestigial, black normal

76.

How many map units are between the genes for body color and wing type?

a)

17

b)

34

c)

9

d)

16

77.

Between which two genes would you expect the highest frequency of recombination?

a)

A and G

b)

W and E

c)

A and W

d)

E and G

78.

What is the correct order of the genes on the chromosome?


g and c 9% recombination frequency

g and l 17% recombination frequency

l and c 9.5% recombination frequency

a)

gcl

b)

lgc

c)

clg

d)

clc

79.

What is the probability that offspring will have the genotype AaGgcc when parental cross is AAGgcc x AaGgcc?

a)

1/4

b)

1/8

c)

1

d)

0

80.

In hydrangeas, flower color can be altered by the pH of the soil. This is an example of...

a)

environment affecting gene expression

b)

synapsis

c)

polygenic inheritance

d)

independent assortment

81.

Why are males more likely to inherit x-linked recessive traits?

a)

They only have one copy of every gene on their X chromosome, their other sex chromosome is s Y

b)

They have two X chromosomes, which masks the dominant allele

c)

They have no X chromosomes

d)

part of their X chromosome is deleted during embryonic development

82.

What inheritance pattern does the white-eyed trait display in fruit flies?

a)

x-linked recessive

b)

autosomal dominant

c)

autosomal recessive

d)

mitochondrial

83.

What is the end result of meiosis?

a)

4 haploid (n) gametes

b)

2 diploid (2n) somatic cells

c)

4 diploid (2n) gametes

d)

2 haploid (n) somatic cells

84.

What is the end result of meiosis?

a)

the daughter cells produced have half the number of chromosomes as the parent cell

b)

the daughter cells produced have the same number of chromosomes as the parent cell

c)

the daughter cells produced have double the number of chromosomes as the parent cell

85.

Which is unique to meiosis and does not occur in mitosis?

a)

homologous chromosomes separate

b)

sister chromatids separate

c)

errors can occur

d)

DNA replication prior to division

86.

Which occurs in both mitosis and meiosis?

a)

homologous chromosomes separate

b)

sister chromatids separate

c)

crossing over

d)

the number of chromosomes is halved

87.

If a diploid cell (2n) in an organism has 56 chromosomes, how many in a sex cell (n) in the same organism?

a)

56

b)

112

c)

28

d)

14

88.

Huntington's is a dominant autosomal disorder. If one parent is heterozygous and has Huntington's and the other parent does not have Huntington's what is the probability that their first and second child will both not have the disorder?

a)

1/4

b)

1/8

c)

1/64

d)

1

89.

In pea plants, purple flower color (P) is dominant to white flower color (p) and Round seed shape (R) is dominant to wrinkled seed shape (r).


A cross between two parents yields a 9:3:3:1 ratio of purple/round, purple/wrinkled, white/round, and white/wrinkled plants


What were the parental genotypes?

a)

PPRr x ppRr

b)

PpRr x PpRr

c)

PpRR x Pprr

d)

ppRr x PpRr

90.

If two parents with the dominant phenotype produce a child with the recessive phenotype, what are their genotypes?

a)

heterozygous

b)

homozygous dominant

c)

homozygous recessive

d)

hemizygous dominant

91.

In order for a child to inherit a dominant trait, what must be true?

a)

both parents must have at least one dominant allele

b)

one parent must have at least one dominant allele

c)

both parents are heterozygous

d)

the parents have no dominant alleles

92.

If a child inherits a mitochondrial disorder, what must be true?

a)

the mother also has the disorder

b)

the father also has the disorder

c)

none of their siblings will inherit the disorder

d)

only males will inherit the disorder

93.

If recombination occurs with low frequency between two genes, what is the most likely reason?

a)

the genes are linked and located close together on the same chromosome

b)

the genes are unlinked and located close together on the same chromosome

c)

the genes are linked and located on separate chromosomes

d)

the genes are unlinked and located on separate chromosomes

94.

If a chi-square analysis reveals that ratios predicted by Mendel's Law of Independent Assortment are not significantly different from observed values, what can be concluded?

a)

the genes are linked and located on separate chromosomes

b)

the genes are unlinked and located on separate chromosomes

c)

the genes are linked and located close together on the same chromosome

d)

the genes are unlinked and located close together on the same chromosome