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Ward AP Bio DNA/RNA Structure and DNA Replication

Total questions: 89

Worksheet time: 45mins

Name
Class
Date
1.
Which type of organism has a larger genome?
a)
Prokaryotes
b)
Eukaryotes
2.
The DNA of eukaryotes contains _____ nucleotides.
a)
more
b)
less
3.

The genome of eukaryotes is typically arranged in _____ piece(s) of DNA.

a)
multiple linear
b)
multiple circular
c)
a single linear
d)
a single circular
4.
A cell contains a single circular chromosome. This cell is likely...
a)
prokaryotic
b)
eukaryotic
5.
______ cells often contain non-coding regions.
a)
prokaryotic
b)
eukaryotic
6.
A plasmid is a(n)...
a)
organelle capable of photosynthesis
b)
type of ribosome found in prokaryotes
c)
type of cell that contains a nucleus but no other organelles
d)
a small double-stranded molecule of DNA
7.
____ is typically double-stranded
a)
DNA
b)
RNA
8.
____ is typically single-stranded
a)
DNA
b)
RNA
9.
The "backbone" of the DNA ladder is made of...
a)
sugar and base
b)
sugar and phosphate
c)
base and phosphate
d)
two bases
10.
Each rug (step) of the DNA ladder is made of...
a)
sugar and base
b)
sugar and phosphate
c)
base and phosphate
d)
two bases
11.
This term describes a nitrogenous base made of a single ring.
a)
Purine
b)
Pyrimidine
12.
This term describes a nitrogenous base made of two rings.
a)
Purine
b)
Pyrimidine
13.
These bases are purines
a)
cytosine and guanine
b)
cytosine and thymine
c)
adenine and thymine
d)
adenine and guanine
14.
These bases are pyrimidines
a)
cytosine and guanine
b)
cytosine and thymine
c)
adenine and thymine
d)
adenine and guanine
15.

In the DNA ladder, a _____ always binds with a pyrimidine

a)
pyrimidine
b)
purine
c)
phosphate
16.
Nitrogenous bases are held together by ____ bonds.
a)
covalent
b)
ionic
c)
hydrogen
d)
polar
17.
Adenine and Thymine are held together by ___ hydrogen bond(s).
a)
1
b)
2
c)
3
d)
4
18.
Cytosine and Guanine are held together by ___ hydrogen bond(s).
a)
1
b)
2
c)
3
d)
4
19.
The two strands of the DNA double helix...
a)
run in the same direction
b)
run in opposite directions
c)
run perpendicular to each other
20.
We say that a strand of DNA runs...
a)
1' to 2'
b)
2' to 4'
c)
3' to 5'
d)
4' to 5'
21.
We say that the two strands of DNA are ____ to one another
a)
perpendicular
b)
parallele
c)
antiparallel
22.
Deoxyribose is the sugar of...
a)
DNA
b)
RNA
23.

RNA contains the sugar (a)   .

24.

The base (a)   is contained in DNA, but not in RNA (use just the letter).

25.

The base (a)   is contained in RNA, but not in DNA (use just the letter).

26.
This enzyme unwinds the two strands of DNA during replication.
a)
DNA polymerase
b)
Helicase
c)
Ligase
d)
RNA Polymerase
e)
Topoisomerase
27.
This enzyme relieves supercoling of the DNA during replication
a)
DNA polymerase
b)
Helicase
c)
Ligase
d)
RNA Polymerase
e)
Topoisomerase
28.
This enzyme joins fragments of the lagging strand.
a)
DNA polymerase
b)
Helicase
c)
Ligase
d)
RNA Polymerase
e)
Topoisomerase
29.
This enzyme breaks the double helix ahead of the replication fork.
a)
DNA polymerase
b)
Helicase
c)
Ligase
d)
RNA Polymerase
e)
Topoisomerase
30.
This enzyme synthesizes a new strand of DNA following a template strand during DNA replication.
a)
DNA polymerase
b)
Helicase
c)
Ligase
d)
RNA Polymerase
e)
Topoisomerase
31.
This enzyme creates a primer to begin a new strand of DNA in DNA replication.
a)
DNA polymerase
b)
Helicase
c)
Ligase
d)
RNA Polymerase
e)
Topoisomerase
32.
When used in DNA replication, this enzyme is sometimes called "primase."
a)
DNA polymerase
b)
Helicase
c)
Ligase
d)
RNA Polymerase
e)
Topoisomerase
33.
This enzyme is most responsible for the creation of the replication fork.
a)
DNA polymerase
b)
Helicase
c)
Ligase
d)
RNA Polymerase
e)
Topoisomerase
34.
This enzyme breaks hydrogen bonds between the nitrogenous bases.
a)
DNA polymerase
b)
Helicase
c)
Ligase
d)
RNA Polymerase
e)
Topoisomerase
35.
This enzyme adds DNA nucleotides to existing nuclotides.
a)
DNA polymerase
b)
Helicase
c)
Ligase
d)
RNA Polymerase
e)
Topoisomerase
36.
This is a short stretch of RNA that is used to start a complementary strand of DNA during replication.
a)
Liger
b)
Primer
c)
Okazaki fragment
d)
Initiator
37.
A new strand of DNA is created in the ____ direction during DNA replication.
a)
3' to 5'
b)
5' to 3'
38.
DNA polymerase READS the template strand in the ____ direction.
a)
3' to 5'
b)
5' to 3'
39.
During DNA replication, the strands are unzipped and...
a)
one strand is broken in to fragments and the other is replicated
b)
each strand is used as a template for a new strand
40.
Each daughter DNA molecule is composed of...
a)
one original strand and one new strand
b)
two new strands
c)
two original strands
41.
DNA replication is considered to be ______.
a)
conservative
b)
semiconservative
c)
dispersive
42.
The _____ strand is made continuously during DNA replication.
a)
leading
b)
lagging
43.
The _____ strand is made in short fragments during DNA replication
a)
leading
b)
lagging
44.
The difference in the way that the leading and lagging strands are made is a result of...
a)
DNA polymerase
b)
Helicase
c)
Ligase
d)
RNA Polymerase
e)
Topoisomerase
45.
New nucleotides are added to the ___ end of an already placed nucleotide.
a)
3'
b)
5'
46.
The lagging strand is created after the leading strand.
a)
true
b)
false
47.
DNA polymerase synthesizes the leading strand and RNA polymerase synthesizes the lagging strand
a)
true
b)
false
48.
DNA replication occurs during the ___ phase of the cell cycle.
a)
G1
b)
G2
c)
S
d)
Mitosis
e)
Cytokinesis
49.
A primer added during DNA replication could contain...
a)
Thymine
b)
Uracil
50.
DNA polymerase moves toward the replication fork when creating the _____ strand
a)
leading
b)
lagging
51.
DNA polymerase moves away from the replication fork when creating the _____ strand
a)
leading
b)
lagging
52.
A replication bubble contains ____ replication forks
a)
1
b)
2
c)
3
d)
4
e)
5
53.
As the replication fork unzips, a new primer would need to be added to the ____ strand
a)
leading
b)
lagging
54.
Of the folloiwng choices, the difference in the way that the leading and lagging strands are made is best attributed to...
a)
the antiparallel nature of the DNA strands
b)
the inability to create more than one primer
c)
the inability of helicase to work in either direction
55.
The _____ strand is created into the replication fork
a)
leading
b)
lagging
56.
The _____ strand is created away from the replication fork
a)
leading
b)
lagging
57.
During DNA replication what is the first process to occur?
a)
Synthesis of the lagging strand
b)
Unwinding of parental DNA
c)
Synthesis of the lagging strand
d)
Sealing of the nicks between short DNA sections
58.
A template reads 3'-ATTCG-5'. The complementary strand would read...
a)
3'-TAAGC-5'
b)
5'-TAAGC-3'
c)
3'-UAAGC-5'
d)
3'-UAAGC-5'
59.
The purpose of DNA replication is...
a)
to create two identical molecules of DNA
b)
to create two complementary molecules of DNA
c)
to create proteins from the DNA instructions
d)
to create genetic diversity in the offspring
60.
DNA replication must occur before...
a)
protein synthesis
b)
cell communication
c)
apoptosis
d)
cell division
61.
Which of the following is a result of DNA replication?
a)
a new protein
b)
recombination of alleles
c)
messenger RNA
d)
sister chromatids
62.
Which number best represents DNA polymerase?
a)
2
b)
3
c)
5
d)
6
e)
9
63.
Which number best represents topoisomerase?
a)
2
b)
3
c)
5
d)
6
e)
9
64.
Which number best represents helicase
a)
2
b)
3
c)
5
d)
6
e)
9
65.
If the replication fork shown continues to open a leading strand will be created using the ____ strand.
a)
top
b)
bottom
66.
If the replication fork shown continues to open a lagging strand will be created using the ____ strand.
a)
top
b)
bottom
67.

What is the shape of DNA?

a)

Double Helix

b)

Single Helix

c)

Square

d)

Circle

68.

The monomer (basic unit) of DNA is the...

a)

Amino acid

b)

Nucleotide

c)

Monosaccharide

d)

Fatty acid

69.

What are nucleotides made up of?

a)

Sugar, Phosphate, Nitrogen Base

b)

Glucose, Carbon, Nitrogen Base

c)

Chromosomes, Sugar, Protein

d)

Polypeptides, Amino Acids, Protein

70.

What part of the DNA nucleotide is colored green in the picture?

a)

Base

b)

Sugar

c)

Phosphate

d)

Chromosome

71.

Which part of the DNA nucleotide is represented as the blue circle in the picture?

a)

Chromosome

b)

Sugar

c)

Phosphate

d)

Base

72.

Which part of the DNA nucleotide is represented as the pink rectangle in the picture?

a)

Chromosome

b)

Sugar

c)

Phosphate

d)

Base

73.

Which image shows the monomer (basic unit) of DNA?

a)

A

b)

B

c)

C

74.

Which two parts of the nucleotide make up the DNA Backbone?

a)

Sugar and base

b)

Sugar and phosphate

c)

Phosphate and base

75.

These create the steps of the DNA ladder.

a)

Bases

b)

Sugars

c)

Phosphates

d)

Amino acids

76.

What is the sugar found in DNA

a)

Ribose

b)

Regular sugar

c)

Protein

d)

Deoxyribose

77.

If one strand of DNA has the sequence of ATGC, what would the complimentary strand be?

a)

TACG

b)

ATGC

c)

HCIR

d)

GACT

78.

In DNA, the base Thymine always bonds with...

a)

Adenine

b)

Cytosine

c)

Guanine

d)

Thymine

79.

In DNA, the base cytosine always bonds with...

a)

Adenine

b)

Cytosine

c)

Guanine

d)

Thymine

80.

What is the complementary DNA strand to this DNA Sequence? ACCTAGG

a)

ACCTAGG

b)

GAACGCC

c)

TGGATCC

d)

AGGTACC

81.

Which of the following lists the correct nitrogenous bases in an RNA molecule?

a)

Adenine, Guanine, Cytosine, Thymine

b)

Uracil, Guanine, Cytosine, Thymine

c)

Adenine, Uracil, Cytosine, Thymine

d)

Adenine, Guanine, Uracil, Cytosine

82.

Generally a _______________________ will have a higher amount of DNA inside than any other type of cell, so the DNA must be highly organized and packaged into chromosomes.

a)

prokaryote

b)

eukaryote

83.

Which nitrogen base is found in RNA and not in DNA?

a)

Adenine

b)

Uracil

c)

Thymine

d)

Guanine

84.

How does all of our DNA fit into our cells

a)

Packaged into astrosomes

b)

Packaged into centromeres

c)

Packaged into chromosomes

d)

It is just floating everywhere inside of the cell

85.

The number of chromosomes in a human somatic (body) cell is...

a)

23

b)

46

c)

64

d)

96

86.

True or False? A tightly coiled bundle of DNA and protein is a chromosome.

a)
False
b)
True
87.

The proteins that DNA tightly winds around are called

a)

nucleosomes

b)

histones

c)

chromatids

d)

centromeres

88.

How many chromosomes do you receive from one parent?

a)

23

b)

46

c)

18

d)

5

89.

The entire structure shown in the diagram is a...

a)
chromatid
b)

replicated chromosome

c)
centromere
d)

unreplicated chromosome