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CSIR-NET LIFESCIENCES TEST-5

Total questions: 74

Worksheet time: 2hrs 28mins

Name
Class
Date
1.

What is the function of nucleic acids?

a)

Energy

b)

Energy Storage

c)

Building Cell Structures

d)

Information Storage

2.

What are 2 types of nucleic acids?

a)

Fatty Acids and Glycerol

b)

DNA and RNA

c)

Amino Acids and Enzymes

d)

Monosaccharides and Polysaccharides

3.

The monomers of nucleic acids are

a)

Nucleotides

b)

Amino Acids

c)

Glycerol

d)

Glucose

4.

Which of the following is NOT part of a nucleotide?

a)

Nitrogenous Base

b)

Phosphate Group

c)

Pentose Sugar

d)

Fatty Acid

5.

What sugar is found in DNA?

a)

Glucose

b)

Ribose

c)

Deoxyribose

d)

Fructose

6.

Which base is ONLY found in DNA?

a)

Cytosine

b)

Guanine

c)

Thymine

d)

Adenine

7.

The image shown is of

a)

DNA

b)

RNA

c)

Fatty Acids

d)

ATP

8.

What molecule is shown here?

a)

Peptide

b)

Amino Acid

c)

Nucleotide

d)

Carbohydrate

9.

Genetic material in Viroids is:

a)

dS Circular - RNA

b)

ss Circular - RNA

c)

dS linear - RNA

d)

ss Linear - RNA

10.

Multipartite is a condition in which :

a)

one segment is present in a single capsid.

b)

One segment is present in multiple capsids

c)

All segments are present in multiple capsids.

d)

All segments are present in a single capsid.

11.

Positive sense RNA means :

A. The genetic material of RNA virus may behave directly as m-RNA in Host.

B. The genetic material of RNA virus may behave as template for mRNA.

C. The genetic material of RNA virus may act as a template for DNA Synthesis.

D. The genetic material of RNA virus may act as a template for RNA Synthesis.

Choose the correct option from the following options :

a)

A & B

b)

A & C

c)

B & C

d)

C & D

12.

Q. Guanine (in its Common form as well as in its Rare form ) can bonds with ______________.

A. Cytosine

B. Adenine

C. Uracil

D. Thymine

a)

A only

b)

B & C .

c)

C only

d)

A & D .

13.

Thymine is also known as :

a)

5-Methyl - 2,4-dioxypyrimidine

b)

5-amino - 2,4-dioxypyrimidine

c)

2-oxy- 4 aminopyrimidine

d)

2-amino 6-oxo purine

14.

STATEMENT -A : Nitrogenous base is planar whereas Sugars are Non-planar.

STATEMENT -B : Nitrogenous base is non-planar whereas Sugars are planar.

a)

Statement-A is correct.

b)

Statement- B is correct.

c)

Both Statement are correct.

d)

No statement is correct.

15.

Statement-1 :In Pseudo uridine :

a)

The glycosidic bond is formed between carbon 1 of Sugar and N1 of Nitrogenous base.

b)

The glycosidic bond is formed between carbon 1 of sugar and C5 of Nitrogenous base.

c)

The glycolytic bond is formed between carbon 1 of Sugar and N1 of Nitrogenous base.

d)

The phosphoester bond is formed between carbon 1 of sugar and C5 of Nitrogenous base.

16.

The Absolute configuration , shape and planarity of Sugar residue in a Nucleoside structure is :

a)

L-type , Furanose type and Planar respectively.

b)

D-type , Furanose and Non-planar with Twisted form respectively.

c)

L-type , Pyranose and Planar with Envelope form respectively.

d)

D-type , Furanose and Non-planar with Envelope form respectively.

17.

On hydrolysis , a nucleoside would not yield ,

a)

Purine

b)

Pyrimidine

c)

Pentose Sugar

d)

Phosphoric Acid

18.

The most abundant intracellular free nucleotide is :

a)

ATP

b)

FAD+

c)

NAD+

d)

NADP+

19.

Correct statement regarding nucleotide structure include which of the following ?

a)

Removal of the 5' Phosphate group from the guanylic acid (GMP) yields guanine.

b)

Removal of the 5' Phosphate group from the adenylic acid (AMP) yields Adenosine.

c)

Removal of the Ribose 5-Phosphate group from the thymidylic acid (TMP) yields Uracil.

d)

Removal of the Ribose 5- Phosphate group from the cytidylic acid (CMP) yields Cytidine.

20.

The purine nucleotides act as the components of :

a)

FAD+

b)

NAD+

c)

NADP+

d)

All of the above

21.

One of the strands of a double stranded DNA with 10,000bp has the following numbers of base residues :

A=3800 and T=2600. The base composition of the whole double stranded molecule will be :

a)

A=5200 , T=5200 , G=4800 , C=4800

b)

A=7600 , T=7600,

, G=2400 , C=2400

c)

A=6400 , T=3600 , G=6400 , C=3600

d)

A=6400 , T=6400 , G=3600 , C=3600.

22.

What is the number of hydrogen bonds in a B-DNA of 1000 base pairs with adenine occuring 75% of the times in one strand and 10% in the other strand?

a)

2150

b)

2820

c)

2250

d)

2750

23.

Which of the following statement is correct ?

a)

The ratio of G to A in double stranded DNA is 1:1.

b)

The ratio of T in double stranded DNA to U in single stranded RNA is 1:2.

c)

The ratio of G to C in single stranded RNA is 1:1.

d)

The ratio of G to C in a double stranded DNA is 1:1.

24.

For a double stranded DNA molecule , which of the following statement is wrong ??

a)

A/T ratio is constant.

b)

G is always equal to C.

c)

A+T is always equal to G+C.

d)

(A+G)/(C+T) ratio is constant.

25.

Which of these is true about the pentoses found in nucleic acids ?

a)

The straight-chain and the ring forms undergo constant interconversion.

b)

The pentoses are always in the beta-furanose forms.

c)

The bond that joins the nitrogen in the ring of the nitrogenous bases to the anomeric carbon of the pentoses is a typical O-glycosidic bond.

d)

Unlike most naturally occuring carbohydrates , they are always in the L-configuration.

26.

A double - stranded DNA has 30 % Thymine . The percentage of Cytosine is :

a)

30%

b)

20%

c)

70%

d)

15%

27.

If RNA in TMV contains 28% cytosine , then what percentage of the bases in TMV is Adenine ?

a)

30%

b)

55%

c)

60%

d)

None.

28.

If a sample of DNA is found to have the base composition of Adenine 40 ; thymine 22 ; Guanine 19 and Cytosine 19. What conclusion can be drawn ?

a)

The DNA is a Circular Duplex.

b)

The DNA is a linear duplex.

c)

The DNA is single stranded.

d)

The DNA has highly repetitive sequences.

29.

If the ratio of (A+G)/(T+C) in one strand of DNA is 0.6 , what is the same ratio in the complementary strand ?

a)

0.6

b)

1.6

c)

0.4

d)

None of the above

30.

Nucleotides can be used as a precursor molecule with the help of :

a)

Deoxyribose Sugar only

b)

Ribose Sugar Only.

c)

Both deoxyribose and Ribose sugars.

d)

None of the above is correct.

31.

The Charges on AMP , ATP and ADP is :

a)

-2 , -3 and -4 respectively.

b)

-3 , -5 and -4 respectively.

c)

-2, -4 and -3 respectively.

d)

-3 , -4 and -5 respectively.

32.

FAD is converted to FADH2 by the addition of :

a)

Hydride ion

b)

2H+

c)

2H and 2e-

d)

2H-

33.

The structure of Coenzyme A includes :

a)

Isoalloxazine Ring

b)

Pantothenic acid

c)

Nicotinamide

d)

Guanine

34.

A DNA molecule has total 100 nucleotides in it. The total charge on the polynucleotide is :

a)

-100

b)

-101

c)

-99

d)

-102

35.

In E.coli , there is a protein coding gene with Molecular Mass of 650 KDa and forms a polypeptide . Finds the molecular mass of polypeptide.

( Given , the average molecular mass of a bp is 650 Da and average molecular mass of amino acid residue is 110Da).

a)

110Da.

b)

36630 Da.

c)

1000 Da.

d)

333Da.

36.

L-shaped DNa is an example of :

a)

Primary DNA

b)

Secondary DNA

c)

Tertiary DNA

d)

Quarternary DNA.

37.

DNA is not hydrolysed by an Alkali , but RNA does . Why?

a)

Due to the Absence of 2'OH in RNA.

b)

Due to the presence of 2'OH and 3'OH in DNA

c)

Due to the Absence of 2'OH in DNA.

d)

Due to the presence of 2'OH in DNA

38.

Which of the following criteria can be used to distinguish between prokaryotic and eukaryotic cells ?

a)

Whether or not they have a plasma membrane

b)

Whether or not they have a nucleus.

c)

Comparison of the sequence of homologous proteins.

d)

Comparison of the signature sequence of 16S rRNA.

39.

Plasma membranes are selectively permeable. This means

a)

anything can pass in and out

b)

the membrane regulates the passage of the material in and out of the cell

c)

glucose cannot enter the cell

d)

cholesterol cannot enter

40.

Membrane phospholipids

a)

have hydrophobic heads that face the center of the membrane and are shielded from water

b)

have hydrophilic tails that face outward

c)

remain fluid because they are tightly packed

d)

none of these

41.

The cholesterol associated with membranes

a)

is attached to proteins and extends into the environment surrounding the cell

b)

helps stabilize the membrane at body temperature

c)

is an abnormality resulting from a diet high in cholesterol

d)

both a and c

42.
lateral movement of phospholipids occur more often than flip-flop movement
a)
true
b)
false
43.

The majority of the plasma membrane is composed of ______.

a)

phospholipids

b)

proteins

c)

carbohydrates

d)

cholesterol

44.

What are the two parts of a phospholipid?

a)

head

b)

enzyme

c)

tail

d)

hormone

45.

The phospholipid head is _____________ & _____________

a)

Hydrophilic

b)

Hydrophobic

c)

Polar (+)

d)

Uncharged

46.

Plasma membranes are selectively permeable. This means

a)

anything can pass in and out

b)

the membrane regulates the passage of the material in and out of the cell

c)

glucose cannot enter the cell

d)

cholesterol cannot enter

47.

The fluid mosaic model describes a membrane consisting of

a)

a phospholipid bilayer with embedded proteins

b)

2 layers of phospholipids with proteins in between

c)

individual proteins and phospholipids that can drift

d)

both a and c

48.

Part A of the picture is pointing to what part of the plasma membrane?

a)

Carbohydrates

b)

Phospholipids

c)

Proteins

d)

Cholesterol

49.

Do not have organelles with membranes

a)

Prokaryotic

b)

Eukaryotic

c)

Both

50.

What type of protein assist in moving specific particles across the membrane?

a)

Membrane-spanning

b)

Surface

c)

Cholesterol

d)

Carbohydrates

51.

Sandwich model of P.M. was given by...

a)

Danielle & Davson

b)

Singer & Nicolson

c)

Grendel & Gorter

d)

De Duve

52.

Fluid Mosaic Model of P.M. was proposed by...

a)

Danielle & Davson

b)

Singer & Nicolson

c)

De Duve

d)

Gorter & Grendel

53.

The membrane protein that extend through both sides of lipid bilayer are...

a)

Intrinsic Proteins

b)

Extrinsic proteins

c)

Peripheral proteins

d)

All of above

54.

A poikilothermic organism living in the Arctic would have , compared to that organism living in the temperate hot climate zone , a plasma membrane richer in :

a)

Cholesterol

b)

Long chain fatty acids

c)

Protein

d)

Unsaturated Fatty Acids

55.

Liposome is :

a)

closed , solvent filled vesicles which have a single bilayer of fatty acid chain.

b)

closed , solvent filled vesicles which have a single layer of fatty acid chain.

c)

a structure made of protein.

d)

both a and b.

56.

Name small compartment enclosed by a membrane formed to transport of material during bulk transport.

a)

vesicles

b)

large vacuole

c)

mitochondria

d)

lysosome

57.

Choose the incorrect statement?

a)

LDL Receptor is a single transmembrane glycoprotein.

b)

LDL contains a large protein called apoB100.

c)

LDL contains cholesterol in the form of cholesterol ester.

d)

Uptake of LDL occurs through COP-I coated receptor mediated endocytosis.

58.

Receptor-mediated endocytosis from plasma membrane requires which one of the following coat proteins ?

a)

Clathrin

b)

SNARE

c)

Caveolin

d)

Glycophorin

59.

The process by which a cell secretes macro-molecules by fusing a vesicle to the plasma membrane is called :

a)

Endocytosis

b)

Exocytosis

c)

Pinocytosis

d)

Phagocytosis

60.

Nitrifying Bacteria are :

a)

Chemolithoautotrophs

b)

Chemorganoautotrophs

c)

Chemolithoheterotrophs

d)

Photoorganoheterotrophs

61.

The three domain classification is based on the ;

a)

16s rRNA signature sequence

b)

16s mRNA signature sequence

c)

23s rRNA signature sequence

d)

23s mRNA signature sequence

62.

Diatoms and Dinoflagellates are :

a)

Photosynthetic protists

b)

Protozoan protists

c)

Monera

d)

Slime moulds

63.

Choose the correct statements regarding Viroids :

A. Non-Cellular , obligate parasites on Plants

B. Non- Cellular , facultative parasites on Plants.

C. Non-coding , single stranded RNA present.

D. Non- Coding , single stranded DNA present.

a)

A & C

b)

B & D

c)

A & D

d)

B & C.

64.

Choose the correct statement :

A. Bacterial viruses perform both Lytic and Lysogenic cycle.

B. The virus performing Lytic Cycle has DNA / RNA as genetic material.

C. The Temperate virus can perform both Lytic as well as Lysogenic Cycle.

D. Temperate viruses has DNA as genetic material.

a)

A & B

b)

A, B & C

c)

A , B , C , D.

d)

A only

65.

Choose the correct statements regarding Plasma Membrane :

A. Robertson model gave Unit membrane model.

B. Davson and Daniele gave the Trilamina Model.

C. Gorter and Grendel said that P.M. is made of Lipid.

D. Acc. to Overton Model , P.M is made of single lipid molecule.

a)

A , B

b)

A , B , C , D.

c)

A , C

d)

C , D.

66.

Phosphotidylcholine and sphingomyelin is present in:

a)

outer leaflet

b)

inner leaflet

67.

Flippase and floppase transports from :

a)

Non cytosolic to Cytosolic and Cytosolic to non cytosolic respectively.

b)

Cytosolic to Non-cytosolic in both

c)

Non- cytosolic to Cytosolic in both

d)

Cytosolic to non-cytosolic and non-cytosolic to cytosolic respectively.

68.

Glycophorin is :

a)

single pass

b)

Multipass

69.

The correct sequence of transportation through lipid bilayer is :

a)

N2 > Water > Glucose > ATP > Ions.

b)

Water > N2 > Ions > Sucrose.

c)

Benzene > Glucose > urea .

d)

Ions > Water > sucrose > urea.

70.

Aquaporin has a conserved amino acid sequence :

a)

Asparagine Proline Alanine

b)

Alanine proline Asparagine

c)

Valine proline leucine

d)

Arginine Proline Alanine

71.

The phosphate binding site in Na- K ATPase is present in which subunit ?

a)

Alpha

b)

Beta

c)

Gamma

d)

Delta

72.

CFTR acts as a

a)

Channel

b)

Carrier

73.

Valinomycin and Gramicidin - A are :

a)

carrier and Channel respectively.

b)

Channel and Carrier respectively.

74.

The Fate of receptor and ligand is same in case of

a)

Ferrotransferrin and its receptor

b)

EGF and its receptor

c)

LDL and its receptor

d)

Ferrotransferrin and EGF both.