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WorksheetsTherapy 5 Review
Total questions: 75
Worksheet time: 44mins
Is S. aureus gram positive or negative? If negative, fermenter or non-fermenter?
positive
negative
fermenter
non-fermenter
Are acinetobacter species gram positive or negative? If negative, fermenter or non-fermenter?
positive
negative
fermenter
non-fermenter
Is Enterococcus faecium gram positive or negative? If negative, fermenter or non-fermenter?
positive
negative
fermenter
non-fermenter
Are enterobacter species gram positive or negative? If negative, fermenter or non-fermenter?
positive
negative
fermenter
non-fermenter
Is Pseudomonas aeruginosa gram positive or negative? If negative, fermenter or non-fermenter?
positive
negative
fermenter
non-fermenter
Are Klebsiella species gram positive or negative? If negative, fermenter or non-fermenter?
positive
negative
fermenter
non-fermenter
Are Proteus species gram positive or negative? If negative, fermenter or non-fermenter?
positive
negative
fermenter
non-fermenter
Is Streptococcus pneumoniae gram positive or negative? If negative, fermenter or non-fermenter?
positive
negative
fermenter
non-fermenter
Is Escherecia coli gram positive or negative? If negative, fermenter or non-fermenter?
positive
negative
fermenter
non-fermenter
To which drug class does cefazolin belong?
1st gen cephalosporin
2nd gen cephalosporin
3rd gen cephalosporin
penicillin
To which drug class does doxycycline belong?
tetracycline
fluoroquinolone
carbapenem
macrolide
To which drug class does amoxicillin belong?
1st gen cephalosporin
aminopenicillin
penicillin
carbapenem
To which drug class does gentamicin belong?
aminoglycoside
fluoroquinolone
cyclic glycopeptide
macrolide
To which drug class does linezolid belong?
oxazolidinone
fluoroquinolone
tetracycline
carbapenem
To which drug class does ciprofloxacin belong?
fluoroquinolone
tetracycline
cyclic glycopeptide
macrolide
To which drug class does ceftriaxone belong?
1st gen cephalosporin
2nd gen cephalosporin
3rd gen cephalosporin
penicillin
To which drug class does imipenem-cilastatin belong?
carbapenem
macrolide
tetracycline
penicillin
To which drug class does daptomycin belong?
tetracycline
macrolide
cyclic glycopeptide
aminoglycoside
To which drug class does azithromycin belong?
tetracycline
macrolide
cyclic glycopeptide
aminoglycoside
What is the brand/generic for azactam?
aztreonam
merrem
zosyn
rocephin
What is the brand/generic for meropenem?
merrem
zyvox
flagyl
linezolid
What is the brand/generic for cefepime?
merrem
maxipime
rocephin
bactrim/septra
What is the brand/generic for levaquin?
levofloxacin
ciprofloxacin
moxifloxacin
metronidazole
What is the brand/generic for piperacillin-tazobactam?
zosyn
unasyn
flagyl
levaquin
What is the brand/generic for zyvox?
linezolid
tetracycline
zosyn
unasyn
What is the brand/generic for sulfamethoxazole-trimethoprim?
bactrim/septra
merrem
azactam
ampicillin/sulbactam
What is the brand/generic for rocephin?
ceftriaxone
cefepime
cefazolin
cephalexin
What is the brand/generic for ampicillin/sulbactam?
zosyn
unasyn
flagyl
levaquin
What is the brand/generic for flagyl?
metronidazole
ceftriaxone
cefepime
aztreonam
Choose the commonly used carbapenems with activity against Pseudomonas aeruginosa.
imipenem-cilastatin
meropenem
imipenem
ertapenem
Aztreonam has only gram _______ coverage.
positive
negative
Colistin has only gram _______ coverage.
positive
negative
Polymixin B has only gram _______ coverage.
positive
negative
Daptomycin has only gram _______ coverage.
positive
negative
Vancomycin has only gram _______ coverage.
positive
negative
Quinupristin-dalfopristin (Synercid) has only gram _______ coverage.
positive
negative
Linezolid has only gram _______ coverage.
positive
negative
Tedizolid (Sivextro) has only gram _______ coverage.
positive
negative
Clindamycin has only gram _______ coverage.
positive
negative
Dalbavancin (Dalvance) has only gram _______ coverage.
positive
negative
Oritavancin (Orbactiv) has only gram _______ coverage.
positive
negative
Telavancin (Vibativ) has only gram _______ coverage.
positive
negative
What is the drug class of choice for MSSA? 2 answers are acceptable.
penicillinase resistant PCNs
1st gen cephalosporin
aminopenicillins
3rd gen cephalosporins
What is the drug of choice for Enterococcus species? (2)
amoxicillin
ampicillin
dicloxacillin
oxacillin
Select the beta-lactams with activity against CREs.
ceftazidime/avibactam (Avycaz)
cefiderocol (Fetroja)
meropenem/vaborabactam (Vabomere)
imipenem-cilastatin/relabactam
piperacillin/tazobactam
Tigecycline does not cover which 3 pathogens?
P. aeruginosa
Proteus
Providencia
MSSA
MRSA
Which of the following are called respiratory fluoroquinolones?
levofloxacin
ciprofloxacin
moxifloxacin
gemifloxacin
gatifloxacin
Which pathogen is covered by the respiratory fluoroquinolones?
S. pneumoniae
P. aeruginosa
Proteus
Providencia
Which drug only has anaerobic coverage?
metronidazole
ciprofloxacin
daptomycin
vancomycin
azithromycin
Which of the following drug classes have atypical coverage?
tetracyclines
macrolides
pleuromutilins
fluoroquinolones
aminopenicillins
Which macrolide has the highest potential for GI adverse effects?
azithromycin
erythromycin
clarithromycin
Tetracyclines are contraindicated in children up to 8 years and pregnant women due to this adverse reaction
tooth/bone discoloration
inhibits normal growth patterns
arthralgia/myalgia
GI adverse effects
Drug class with potential CNS side effects (eg. confusion) that are more likely to occur in elderly patients
fluoroquinolones
carbapenems
macrolides
tetracyclines
Which beta-lactam class is most likely to cause seizures?
carbapenems
penicillins
cephalosporins
monobactams
What is the unique adverse of rifampin?
red/orange discoloration of sweat, urine, tears
seizures
BBW for tooth and bone discoloration
nephrotoxicity
What is the most common adverse reaction associated with colistin or polymixin B?
nephrotoxicity
hepatotoxicity
ototoxicity
fetal harm
Which of the following are in the BBW for plazmomicin?
nephrotoxicity
ototoxicity
neuromuscular toxicity
fetal harm
hepatotoxicity
This agent has the potential to cause thrombocytopenia. which is more common with >2 weeks of therapy:
linezolid
erythromycin
plazomicin
sulfamethoxazole/trimethoprim
Drug that frequently causes arthralgias/myalgias, limiting its clinical utility:
quinupristin-dalfopristin
tygecycline
erythromycin
linezolid
This antibiotic has one of the highest potentials for GI effects (occurs in up to 30% of cases)
tygecycline
synercid
erythromycin
linezolid
Which drug is inactivated by pulmonary surfactant and therefore should not be used for pneumonia?
daptomycin
vancomycin
piperacillin-tazobactam
dalbavancin
Which medication has minimal systemic absorption and should only be used for the treatment of C. difficile infection?
oral vancomycin
fidaxomicin
daptomycin
metronidazole
IV vancomycin
Why is unfractionated heparin contraindicated for up to 5 days after the administration of oritavancin?
artificially prolongs aPTT for up to 120 hours
INR is falsely elevated
This IV agent rapidly distributes into the periphery and should not be used for the treatment of bacteremia
tigecycline
doxycycline
ampicillin/sulbactam
Choose the drug classes that have potential to cause QTc prolongation, and therefore should be used cautiously with other QTc prolonging drugs
fluoroquinolones
macrolides
pleuromutilins
lipoglycopeptide
aminoglycopeptide
Rifampin is a strong inducer of which isoenzymes?
3A4
1A2
2C9
2C19
2D6
Which agents have a very long half-lives, allowing for infrequent administration (one or two doses for entire treatment course)?
dalbavancin
oritavancin
vancomycin
erythromycin
Which agent should be avoided in patients with a G6PD deficiency?
sulfamethoxazole/trimethoprim
ampicillin/sulbactam
oritavancin
fidaxomicin
Which drug classes have the potential to increase the effects of warfarin?
fluoroquinolones and macrolides
nitroimidazole
folate antagonist
tetracyclines
glycylcyclines
These drug classes should not be administered with Ca, Fe, Mg, Al containing compounds due to potential for decreased absorption
fluoroquinolones
tetracyclines
macrolides
What is the drug class of choice for treatment of ESBLs?
carbapenems
penicillins
monobactams
fluoroquinolones
Which beta-lactams are active against many MDR Pseudomonas isolates?
ceftolozane/tazobactam
ceftazidime/avibactam
imipenem-cilastatin/relabactam
ESBLs are identified by resistance to which drug classes?
1st gen cephalosporins
2nd gen cephalosporins
3rd gen cephalosporins
monobactams
tetracyclines
If double covering for P. aeruginosa, it is recommended to use an antipseudomonal beta-lactam plus what?
aminoglycosides
fluoroquinolones
tetracyclines
macrolides
monobactams
Does this quiz include all but Sheet 7 numbers 1-4 and 10 because they were too long and should you study them separately from this?
yes
yes again to make sure you actually do it
