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Worksheetsnervous system drugs
Total questions: 130
Worksheet time: 11hrs 50mins
neurotransmitter during times of stress
(a)
neurotransmitter during normal body functioning
(a)
all are sympathetic response except for:
dilates pupil
stimulates saliva to flow
dilates bronchioles
inhibits peristalsis and secretion
contracts bladder
all are parasympathetic response except for:
relaxes bladder
inhibits flow of saliva
constricts pupils
constricts bronchioles
stimulates peristalsis and secretions
Alpha 1
Increase force of heart contraction
Increases blood pressure
Dilates pupils
Decreases salivary gland secretion
Increases urinary bladder relaxation and urinary sphincter contraction
Produces hypotension
Decreases GI motility and tone
Increases myocardial contraction and heart rate
Increases renin secretion (from kidneys) which then increases blood pressure.
Dilates bronchioles
Promotes GI relaxation
Relaxes uterine muscles causing decreasing in uterine contraction
Promotes increase in blood sugar through glycogenolysis in liver
Increases blood flow in skeletal muscles
Alpha 2
Produces hypotension
Decreases GI motility and tone
Increase force of heart contraction
Increases blood pressure
Dilates pupils
Decreases salivary gland secretion
Increases urinary bladder relaxation and urinary sphincter contraction
Increases myocardial contraction and heart rate
Increases renin secretion (from kidneys) which then increases blood pressure.
Dilates bronchioles
Promotes GI relaxation
Relaxes uterine muscles causing decreasing in uterine contraction
Promotes increase in blood sugar through glycogenolysis in liver
Increases blood flow in skeletal muscles
Beta 1
Increases myocardial contraction and heart rate
Increases renin secretion (from kidneys) which then increases blood pressure.
Produces hypotension
Decreases GI motility and tone
Increase force of heart contraction
Increases blood pressure
Dilates pupils
Decreases salivary gland secretion
Increases urinary bladder relaxation and urinary sphincter contraction
Dilates bronchioles
Promotes GI relaxation
Relaxes uterine muscles causing decreasing in uterine contraction
Promotes increase in blood sugar through glycogenolysis in liver
Increases blood flow in skeletal muscles
Beta 2
Dilates bronchioles
Promotes GI relaxation
Relaxes uterine muscles causing decreasing in uterine contraction
Promotes increase in blood sugar through glycogenolysis in liver
Increases blood flow in skeletal muscles
Increases myocardial contraction and heart rate
Increases renin secretion (from kidneys) which then increases blood pressure.
Increase force of heart contraction
Increases blood pressure
Dilates pupils
Decreases salivary gland secretion
Increases urinary bladder relaxation and urinary sphincter contraction
Produces hypotension
Decreases GI motility and tone
inactivates the action of norepinephrine through reuptake, through enzyme transformation or degradation or through diffusion away from the neuron so that the increase in the heart rate and increase in bp will not be prolonged whenever there is a sympathetic action
Monoamine Oxidase
Cathecol-O-Methyltransferase
Cholinergic blockers
Adrenergic blockers
Cholinergic agonist
stimulates the receptor, which are alpha 1, beta 1 and beta 2 (have similar sympathetic action)
(a)
It is not the receptors that are stimulated but the release of norepinephrine
(a)
alpha 1 drugs
Midodrine
Phenylephrine
Clonidine
Methyldopa
Terbutaline
alpha 2 drugs
Clonidine
Methyldopa
Phenylephrine
Midodrine
Isotharine
if you give adrenergic drugs PO, you have to offer it with food to prevent nausea and vomiting, or to lessen GI upset
True
False
Beta 1 Drugs
Dobutamine
Albuterol
Isotharine
Terbutaline
beta 2 drugs
Dobutamine
Albuterol
Isotharine
Terbutaline
beta 1 and beta 2 drugs
Terbutaline
Metaproterenol
Ritodrine
Epinephrine
Norepinephrine
alpha and beta drugs
Epinephrine
Ephedrine
Norepinephrine
Dopamine
Pseudoephedrine
allergy: rashes, skin problems
(a)
allergy: anaphylaxis
(a)
mixed drugs for nasal congestion
Ephedrine
Pseudoephedrine
Phenylephrine
Albuterol
The drugs for Parkinson's disease are just the precursors of dopamine but not dopamine itself.
True
False
Carbidopa, Levodopa
Dopaminergics
Dopamine Agonists
MAO-B Inhibitors
COMT Inhibitors
Anticholinergic s-Antiparkinso ns
Decrease symptoms, very effective in the early course of disease
Amantadine, Bromocriptine, Pramipexole
Selegiline HCl, Rasagiline
Entacopone, Tolcapone
Cogentin, artane
Carbidopa, Levodopa
Inhibits catabolic enzymes of dopamine, extends action of dopamine
Selegiline HCl, Rasagiline
Carbidopa, Levodopa
Amantadine, Bromocriptine, Pramipexole
Entacopone, Tolcapone
Cogentin, artane
COMT Inhibitors
Entacopone, Tolcapone
Cogentin, artane
Carbidopa, Levodopa
Amantadine, Bromocriptine, Pramipexole
Selegiline HCl, Rasagiline
Decrease tremors, but contraindicated in myasthenia gravis
Cogentin, artane
Carbidopa, Levodopa
Amantadine, Bromocriptine, Pramipexole
Selegiline HCl, Rasagiline
Entacopone, Tolcapone
alpha 1 antagonist
Decreases blood pressure
Causes reflex tachycardia
Constricts pupils
Suppresses ejaculation
Reduces contraction of bladder neck
Decreases heart rate
Reduces force of myocardial contraction
Constricts bronchioles
Contracts uterus
Inhibits glycogenolysis which lowers blood sugar
beta 1 antagonist
Decreases heart rate
Reduces force of myocardial contraction
Decreases blood pressure
Causes reflex tachycardia
Constricts pupils
Suppresses ejaculation
Reduces contraction of bladder neck
Constricts bronchioles
Contracts uterus
Inhibits glycogenolysis which lowers blood sugar
beta 2 antagonist
Constricts bronchioles
Contracts uterus
Inhibits glycogenolysis which lowers blood sugar
Decreases blood pressure
Causes reflex tachycardia
Constricts pupils
Suppresses ejaculation
Reduces contraction of bladder neck
Decreases heart rate
Reduces force of myocardial contraction
Antidote for norepinephrine and dopamine
Tolazoline
Phentolamine mesylate
Doxazosin mesylate
Prazosin
Terazosin
ALPHA ADRENERGIC BLOCKERS
Tolazoline
Phentolamine
Doxazosin
Prazosin
Terazosin
Carteolol
Penbutolol
Propranolol
Nadolol
Pindolol
Carvedilol
Labetalol
prevent migraine because it decreases the release of norepinephrine
Timolol
Metoprolol
Atenolol
Betaxolol
BETA ADRENERGIC BLOCKERS
Tolazoline
Phentolamine
Doxazosin
Prazosin
Terazosin
Carteolol
Penbutolol
Propranolol
Nadolol
Pindolol
Carvedilol
Labetalol
ALPHA AND BETA ADRENERGIC BLOCKERS
Tolazoline
Phentolamine
Doxazosin
Prazosin
Terazosin
Carteolol
Penbutolol
Propranolol
Nadolol
Pindolol
Carvedilol
Labetalol
cholinergic receptors
(a)
Stimulates smooth muscles
Slows heart rate
(a)
Stimulates skeletal muscles
(a)
Direct Acting cholinergics
Acts on a receptor to stimulate a response and primarily selective to muscarinic receptors
Inhibits action of enzyme cholinesterase or acetylcholinesterase which destroys acetylcholine
Indirect Acting cholinergics
Acts on a receptor to stimulate a response and primarily selective to muscarinic receptors
Inhibits action of enzyme cholinesterase or acetylcholinesterase which destroys acetylcholine
direct acting cholinergic drug for urinary retention
Bethanechol
Metoclopramide
Carbachol
Pilocarpine
direct acting cholinergic drug for gerd
Bethanechol
Metoclopramide
Carbachol
Pilocarpine
Reduces IOP, causes miosis
Bethanechol
Metoclopramide
Carbachol
Pilocarpine
Alzheimer's Cholinesterase Inhibitors
Tacrine
Donepezil
Rivastigamine
Galantamine
Demecarium bromide
Echothiophate iodide
Edrophonium
Ambenonium
Pyridostigmine bromide
Neostigmine
Physostigmine salicylate
Pralidoxime HCI
Glaucoma's Cholinesterase Inhibitors
Tacrine
Donepezil
Rivastigamine
Galantamine
Demecarium bromide
Echothiophate iodide
Edrophonium
Ambeonium
Pyridostigmine bromide
Neostigmine
Physostigmine salicylate
Pralidoxime HCI
Myasthenia Gravis Cholinesterase Inhibitors
Tacrine
Donepezil
Rivastigamine
Galantamine
Demecarium bromide
Echothiophate iodide
Edrophonium
Ambenonium
Pyridostigmine bromide
Neostigmine
Physostigmine salicylate
Pralidoxime HCI
Pralidoxime will inhibit cholinesterase
True
False
Preoperative medication to reduce salivation, increase heart rate, and dilate pupils
Atropine
Hyoscyamine
Scopolamine
Tropicamide
Benztropine
For Peptic ulcer, irritable bowel syndrome (IBS). Decreases peristalsis
Atropine
Hyoscyamine
Scopolamine
Tropicamide
Benztropine
Pre-anesthetic drug, motion sickness, delirium, IBS. They interfere with nerve impulses by acetylcholine that work directly on the vomiting center of the brain.
Atropine
Hyoscyamine
Scopolamine
Tropicamide
Benztropine
Mydriasis. Pwede for eye surgery
Atropine
Hyoscyamine
Scopolamine
Tropicamide
Benztropine
Antiparkinsonian
Atropine
Hyoscyamine
Scopolamine
Tropicamide
Benztropine
Bronchodilator for COPD. Best combined with adrenergic drugs. Cause drowsiness in chronic use. Can cause photophobia, dry mouth, decrease in urination, and constipation
Ipratropium
Atomoxetine
Modafinil
thiopental
under medication
result in respiratory failure
(a)
over medication
causing low heart rate, low bp, muscle cramps, and paralysis
(a)
Stimulates norepinephrine and dopamine and causes euphoria and alertness, but can also cause sleepiness, restlessness, tremors, and irritability
(a)
responsible for reward and pleasure
(a)
Acidic urine excretes amphetamines faster than alkaline urine
True
False
Nacrolepsy drugs
Armodafinil
Modafinil
Dextroamphetamine Sulfate
Methylphenidate
Dexmethylphenidate
Methamphetamine
Lisdexamfetamine
Atomoxetine
Dextroamphetamine
Benzphetamine
Sibutramine
Mazindol
Phentermine
Orlistat
theophylline
caffeine
ADHD drugs
Methylphenidate
Dexmethylphenidate
Methamphetamine
Lisdexamfetamine
Atomoxetine
Dextroamphetamine
Benzphetamine
Sibutramine
Mazindol
Phentermine
Orlistat
theophylline
caffeine
Armodafinil
Modafinil
Dextroamphetamine Sulfate
Treats obesity by suppressing appetite, but self medication is contraindicated.
Not recommended for children below 12 years of age.
Has stimulant effect on the hypothalamic and limbic regions of the brain that controls satiety
(a)
Anorexiant drugs
Dextroamphetamine
Benzphetamine
Sibutramine
Mazindol
Phentermine
Orlistat
theophylline
caffeine
Armodafinil
Modafinil
Dextroamphetamine Sulfate
Methylphenidate
Dexmethylphenidate
Methamphetamine
Lisdexamfetamine
Atomoxetine
Affects cerebral cortex, brainstem, and spinal cord which stimulate respiration.
(a)
methylxanthines are contrainicated against neonatal apnea
True
False
Analeptic drugs
theophylline
caffeine
Armodafinil
Modafinil
Dextroamphetamine Sulfate
Methylphenidate
Dexmethylphenidate
Methamphetamine
Lisdexamfetamine
Atomoxetine
Dextroamphetamine
Benzphetamine
Sibutramine
Mazindol
Phentermine
Orlistat
Respiratory CNS Stimulant
used to treat respiratory depression caused by drug overdose, COPD, and anesthesia
(a)
Are contraindicated in pregnancy, it is category X. It is a CNS stimulant so check for BP and sensations such as weakness and numbness, these are serious side effects that the patient needs to report.
(a)
Calms and causes sleep. For insomnia, hangover and preoperative medications
(a)
Mildest form of CNS depression
(a)
Ultrashort acting barbiturates
thiopental
pentobarbital
butabarbital
mephobarbital
chloral hydrate
Short acting
induces sleep, if you wanted to sleep, no hangover
secobarbital
pentobarbital
butabarbital
mephobarbital
chloral hydrate
Intermediate acting barbiturates
butabarbital
thiopental
secobarbital
mephobarbital
chloral hydrate
Long acting
sustains sleep, if you wanted to have longer sleeps, it has hangover
mephobarbital
butabarbital
thiopental
chloral hydrate
chloral hydrate causes no hangover and less respiratory depression
True
False
alleviates anxiety and may cause sleepiness
Alprazolam
Estazolam
Flurazepam
Lorazepam
Zolpidem
Estazolam
new treatment for insomnia, but should no be used longer than 6 weeks
for insomnia
for preoperative sedative and reduces anxiety
for benzodiazepine overdose or reversal of sedative effects of benzodiazepine with general anesthesia (will wake you up)
treats insomnia
for/treats insomnia
Flurazepam
Zolpidem
Flumazenil
Lorazepam
Lorazepam
for preoperative sedative and reduces anxiety
for benzodiazepine overdose or reversal of sedative effects of benzodiazepine with general anesthesia (will wake you up)
treats insomnia
alleviates anxiety and may cause sleepiness
Zolpidem is under benzodiazepines
True
False
Flumazenil is for benzodiazepine overdose or reversal of sedative effects of benzodiazepine with general anesthesia (will wake you up)
True
False
FOR GENERAL ANESTHESIA (sleep like state)
Thiopental Na
Droperidol
Etomidate
Ketamine
Midazolam
Propofol
CONSCIOUS SEDATION (you are awake and relax but no pain)
Midazolam
Propofol
Thiopental Na
Droperidol
Etomidate
Ketamine
Induction stage that begins with consciousness and ends with loss of consciousness where speech is difficult, sensations are lost, and dreams and hallucinations may occur.
ANALGESIA
EXCITEMENT OR DELIRIUM
SURGICAL
MEDULLARY PARALYSIS
SHORT ACTING LOCAL ANESTHETICS
Chloroprocaine
Procaine
Lidocaine
Mepivacaine
Prilocaine
Bupivacaine
Dibucaine
Etidocaine
Tetracaine
MODERATE ACTING LOCAL ANESTHETICS
Lidocaine
Mepivacaine
Prilocaine
Chloroprocaine
Procaine
Bupivacaine
Dibucaine
Etidocaine
Tetracaine
LONG ACTING LOCAL ANESTHETICS
Bupivacaine
Dibucaine
Etidocaine
Tetracaine
Chloroprocaine
Procaine
Lidocaine
Mepivacaine
Prilocaine
Both left and right hemisphere is affected
GENERALIZED SEIZURE
ABSENCE SEIZURE
STATUS EPILEPTICUS
TONIC CLONIC SEIZURE
PARTIAL COMPLEX SEIZURE
staring blankly, sudden lapses on consciousness for 15 seconds
ABSENCE SEIZURE
STATUS EPILEPTICUS
TONIC CLONIC SEIZURE
PARTIAL COMPLEX SEIZURE
MYOCLONIC SEIZURE
stiffening-jerking
TONIC CLONIC SEIZURE
MYOCLONIC SEIZURE
PARTIAL COMPLEX SEIZURE
STATUS EPILEPTICUS
seizures more than 5 minutes is STATUS EPILEPTICUS
True
False
blank stare then repetitive physical activity. Ex muffled speech, daydreaming, intoxicated
PARTIAL COMPLEX SEIZURE
Febrile seizures
MIXED SEIZURE
MYOCLONIC SEIZURE
brief jerky movements, either one muscle or group of muscles is MYOCLONIC SEIZURE
True
False
BARBITURATES Phenobarbital
GENERALIZED SEIZURE
ABSENCE SEIZURE
STATUS EPILEPTICUS
TONIC CLONIC SEIZURE
PARTIAL COMPLEX SEIZURE
BENZODIAZEPINES Diazepam
STATUS EPILEPTICUS
ABSENCE SEIZURE
TONIC CLONIC SEIZURE
PARTIAL COMPLEX SEIZURE
GENERALIZED SEIZURE
HYDANTOINS Phenytoin
TONIC CLONIC SEIZURE
PARTIAL COMPLEX SEIZURE
STATUS EPILEPTICUS
MYOCLONIC SEIZURE
ABSENCE SEIZURE
SUCCINIMIDES
ABSENCE SEIZURE
GENERALIZED SEIZURE
TONIC CLONIC SEIZURE
PARTIAL COMPLEX SEIZURE
STATUS EPILEPTICUS
ACETAZOLAMIDE (DIAMOX)
TONIC CLONIC SEIZURE
ABSENCE SEIZURE
MYOCLONIC SEIZURE
STATUS EPILEPTICUS
PARTIAL COMPLEX SEIZURE
CARBAMAZEPINE (TEGRETOL)
TONIC CLONIC SEIZURE
PARTIAL COMPLEX SEIZURE
MIXED SEIZURE
ABSENCE SEIZURE
STATUS EPILEPTICUS
VALPROIC ACID (DEPAKENE) is for ABSENCE SEIZURE
True
False
Regulates anxiety (motor movement)
(a)
Associated with arousal and general CNS activity levels (well being, happiness, mood, emotion, perception, sleep)
(a)
Regulates cognition, emotional responses, and motivation
(a)
Control of arousal, attention, vigilance, mood, affect, and anxiety (concentration, manic responses)
(a)
Plays a role in sleep and wakefulness
(a)
Antipsychotics _ action of dopamine
stimulate
block
A chronic psychotic disorder of losing contact with reality manifested in a variety of mental or psychiatric disorders resulting from imbalanced dopamine in the brain
(a)
PHENOTHIAZINES
Chlorpromazine
Fluphenazine
Perphenazine
Thioridazine
Haloperidol
Loxapine
Molindone
Clozapine
Olanzapine
Quetiapine
Risperidone
Ziprasidone
Aripiprazole
Paliperidone
NON PHENOTHIAZINES
Haloperidol
Loxapine
Molindone
Clozapine
Olanzapine
Quetiapine
Risperidone
Ziprasidone
Aripiprazole
Paliperidone
Chlorpromazine
Fluphenazine
Perphenazine
Thioridazine
THIOXANTHENES
Clozapine
Olanzapine
Quetiapine
Risperidone
Ziprasidone
Aripiprazole
Paliperidone
Chlorpromazine
Fluphenazine
Perphenazine
Thioridazine
Haloperidol
Loxapine
Molindone
EXTRAPYRAMIDAL SYNDROME (EPS) OR PSEUDOPARKINSONISM
ACUTE DYSTONIA
AKATHISIA
TARDIVE DYSKINESIA
MUSCLE RIGIDITY
SERIOUS BUT TREATABLE
ACUTE DYSTONIA
Facial grimacing; involuntary upward eye movement; muscle spasms of tongue, face, neck, and back; and laryngeal spasms
Restless; trouble standing still; paces the floor; feet in constant motion; and rocking back and forth
Protrusion and rolling of tongue; sucking and smacking movement of lips; chewing motion; facial dyskinesia; and involuntary movements of body and extremities
Muscle rigidity, sudden high fever, altered mental status, BP fluctuations, tachycardia, dysrhythmia, seizures, respiratory failure, coma, acute renal failure, rhabdomyolysis
Restless; trouble standing still; paces the floor; feet in constant motion; and rocking back and forth
ACUTE DYSTONIA
AKATHISIA
TARDIVE DYSKINESIA
NEUROLEPTIC MALIGNANT SYNDROME
TARDIVE DYSKINESIA
Protrusion and rolling of tongue; sucking and smacking movement of lips; chewing motion; facial dyskinesia; and involuntary movements of body and extremities
Restless; trouble standing still; paces the floor; feet in constant motion; and rocking back and forth
Facial grimacing; involuntary upward eye movement; muscle spasms of tongue, face, neck, and back; and laryngeal spasms
Stooped posture, shuffling gait, rigidity, bradykinesia, tremors at feet, rolling motion of hands
Alprazolam
anxiety, panic disorders, and depression
alcohol withdrawal, anxiety, and tension
anxiety, alcohol withdrawal, and partial seizures
anxiety, muscle spasms, alcohol withdrawal, status epilepticus, and preoperative sedation
anxiety alcohol withdrawal
alcohol withdrawal, anxiety, and tension
Alprazolam
Chlordiazepoxide
Clorazepate
Diazepam
Lorazepam
Clorazepate
anxiety, panic disorders, and depression
alcohol withdrawal, anxiety, and tension
anxiety, alcohol withdrawal, and partial seizures
anxiety, muscle spasms, alcohol withdrawal, status epilepticus, and preoperative sedation
anxiety alcohol withdrawal
anxiety, muscle spasms, alcohol withdrawal, status epilepticus, and preoperative sedation
Alprazolam
Chlordiazepoxide
Clorazepate
Diazepam
Lorazepam
Lorazepam
anxiety, panic disorders, and depression
alcohol withdrawal, anxiety, and tension
anxiety, alcohol withdrawal, and partial seizures
anxiety, muscle spasms, alcohol withdrawal, status epilepticus, and preoperative sedation
anxiety alcohol withdrawal
AZAPIRONES
anxiety, depression
Buspirone
Flumazenil
A benzodiazepine antagonist which reverses benzodiazepine effects.
Flumazenil
Buspar
REACTIVE DEPRESSION DRUG OF CHOICE
Benzodiazepines
Antidepressants
Lithium
MAJOR DEPRESSION DRUG OF CHOICE
Antidepressants
Benzodiazepines
Lithium
BIPOLAR AFFECTIVE DISORDER DRUG OF CHOICE
Lithium
Benzodiazepines
Antidepressants
blocks norepinephrine and serotonin
TRICYCLICANTIDEPRESSANTS
SELECTIVE SEROTONIN REUPTAKE INHIBITOR
ATYPICALANTIDEPRESSANTS
MONOAMINE OXIDASE INHIBITORS
blocks serotonin
TCA
SSRI
ATYPICALANTIDEPRESSANTS
MAOI
affects norepinephrine, serotonin, and dopamine
TCA
SSRI
ATYPICALANTIDEPRESSANTS
MAOI
TRICYCLICANTIDEPRESSANTS
Amitriptyline
Clomipramine
Imipramine
Fluoxetine
Paroxetine
Amoxapine
Isocarboxazid
Phenelzine
Trancyclopromine
Selegiline
SELECTIVE SEROTONIN REUPTAKE INHIBITOR
Fluoxetine
Paroxetine
Amoxapine
Isocarboxazid
Phenelzine
Trancyclopromine
Selegiline
Amitriptyline
Clomipramine
Imipramine
ATYPICALANTIDEPRESSANTS
Amoxapine
Isocarboxazid
Phenelzine
Trancyclopromine
Selegiline
Amitriptyline
Clomipramine
Imipramine
Fluoxetine
Paroxetine
MONOAMINE OXIDASE INHIBITORS
Isocarboxazid
Phenelzine
Trancyclopromine
Selegiline
Amitriptyline
Clomipramine
Imipramine
Fluoxetine
Paroxetine
Amoxapine
