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Ch9 Protein Synthesis (Whole Ch)

Total questions: 73

Worksheet time: 37mins

Name
Class
Date
1.

A segment of DNA that codes for a specific protein.

a)

Chromosome

b)

Autosome

c)

Gene

d)

RNA

2.

A sequence of DNA that specifies the beginning of a gene sequence

a)

Promoter Sequence

b)

Terminator Sequence

c)

Chromatid

d)

Start Codon

3.

A sequence of DNA that specifies the end of a gene sequence

a)

Promoter Sequence

b)

Terminator Sequence

c)

Start Codon

d)

Stop Codon

4.

Which of the following best describes the order of information flow in living things?

a)

DNA->Protein->RNA

b)

RNA->Protein->DNA

c)

DNA->RNA->Protein

d)

Protein->DNA->RNA

5.

The process of copying gene information from DNA into RNA

a)

Replication

b)

Transcription

c)

Translation

d)

Transformation

6.

The process of making proteins from information in RNA

a)

Replication

b)

Transcription

c)

Translation

d)

Transformation

7.

The process of copying DNA (creating more identical DNA molecules)

a)

Replication

b)

Transcription

c)

Translation

d)

Transformation

8.

Proteins are directly made from information in which molecule?

a)

DNA

b)

RNA

c)

Both

d)

Neither

9.

One difference between DNA and RNA is...

a)

DNA is left handed and RNA is right handed.

b)

DNA is double stranded and RNA is single stranded

c)

RNA is double stranded and DNA is single stranded

d)

DNA is made of nucleotides and RNA is not.

10.

One difference between DNA and RNA is the 5-carbon sugar found in the nucleotides. RNA uses ______ instead of _______.

a)

Ribose; Deoxyribose

b)

Deoxyribose, Ribose

c)

Uracil; Thymine

d)

Thymine; Uracil

11.

DNA and RNA differ in the nitrogenous bases used in their nucleotides. Which of the following would be the four bases used in RNA?

a)

A, T, C, G

b)

T, U, C, G

c)

A, U, C, G

d)

A, T, U, G

12.

If RNA is more directly used to make proteins, why isn't isn't it just used as the main genetic material instead of DNA?

a)

DNA is more stable, leading to less mutation over time.

b)

RNA can't fit in the nucleus

c)

Because RNA can't carry genetic information.

d)

There isn't any specific reason. It is just that way.

13.

Which of the following molecules would NOT be a part of transcription?

a)

Template DNA Strand

b)

Free nucleotides (Uracil, Adenine, Cytosine, Guanine)

c)

RNA Polymerase

d)

DNA Polymerase

14.

What is the product of transcription?

a)

New DNA strands

b)

pre-mRNA

c)

RNA Polymerase

d)

Protein

15.

The enzyme that transcribes DNA into RNA

a)

DNA Polymerase

b)

DNA Helicase

c)

RNA Polymerase

d)

Ribosomes

16.

Where does transcription occur in the cell?

a)

Ribosome

b)

Nucleus

c)

Mitochondria

d)

It occurs outside of the cell

17.

Why is the product of transcription called a "pre-mRNA" molecule?

a)

The pre-mRNA needs to be processed by removing the introns before it is mRNA.

b)

The pre-mRNA needs to be processed by removing the exons before it is mRNA.

c)

The pre-mRNA needs to be folded before it is an mRNA.

d)

mRNA is built during translation

18.

DNA is double stranded, so technically only one of the two strands contains the genetic code. What is the name for the strand that contains the genetic code and is transcribed?

a)

The promoter

b)

The template strand

c)

Pre-mRNA

d)

The terminator

19.

The segments of pre-mRNA that are removed during gene processing.

a)

Introns

b)

Exons

c)

Spliceosomes

d)

Codons

20.

The segments of pre-mRNA that are kept during gene processing and will become part of the mRNA molecule.

a)

Introns

b)

Exons

c)

Spliceosomes

d)

Codons

21.

The "m" in mRNA stands for...

a)

Mitochondrial

b)

Magic

c)

Messenger

d)

Mature

22.

Which of the following molecules would contain the genetic sequence for one specific protein?

a)

DNA

b)

mRNA

c)

pre-mRNA

d)

tRNA

23.

The enzyme complex responsible for removing introns during gene processing.

a)

RNA Polymerase

b)

DNA Polymerase

c)

Spliceosomes

d)

DNA Helicase

24.

Which of the following best describes why introns and exons exist?

a)

The presence of introns/exons means that a single DNA sequence can possibly produce more than one type of protein, depending on hw the pre-mRNA is processed.

b)

The presence of introns/exons is an evolutionary consequence of a living thing becoming complex.

c)

The presence of introns/exons has no purpose.

d)

The presence of introns/exons means that a single DNA sequence can code for every protein in a cell.

25.

Protein Synthesis involves two steps: In the first, DNA is copied into RNA. This process is called _________. In the second, RNA is used to make proteins. This is called _________.

a)

Transcription; Translation

b)

Translation; Transcription

c)

Replication; Transcription

d)

Replication; Translation

26.

Which of the following would be the correct sequence of pre-mRNA based on the sequence of template DNA below:

T T C G A T A G

a)

A A G C T A T C

b)

A A G C U A U C

c)

U U C G A U A G

d)

T T C G A T A G

27.

Which of the following molecules leaves the nucleus, and how?

a)

DNA; exocytosis

b)

mRNA; exocytosis

c)

DNA; via the nuclear pores

d)

mRNA; via the nuclear pores

28.

DNA contains "Deoxyribose" sugars and RNA contains "Ribose" sugars. Look closely at those two words and you will see a relationship. Based on the names, what is the difference between these two molecules?

a)

Deoxyribose is like ribose but deoxyribose is lacking an oxygen atom.

b)

Ribose is like deoxyribose but ribose is lacking an oxygen atom.

c)

There doesn't appear to be any relationship between these two molecules.

29.

Where would you find promoter and terminator sequences?

a)

pre-mRNA

b)

Template DNA

c)

mRNA

d)

RNA Polymerase

30.

Why are certain proteins made in one cell but not in another?

a)

It is based on the DNA in each cell. They might have different DNA.

b)

Each cell may have different transcription factors activated that regulate protein synthesis.

c)

The brain tells certain cells to make or not make specific proteins.

d)

Cells just know what they need to make or not make.

31.

A gene that is actively being transcribed by a cell, resulting in the production of its specific protein.

a)

Expression

b)

Mutation

c)

Replication

d)

Processing

32.

The subunits that build proteins

a)

Nucleic Acids

b)

Amino Acids

c)

Nucleotides

d)

Fatty Acids

33.

There are (#) ____ different types of amino acids found in living things

a)

Thousands

b)

20

c)

100

d)

Millions

34.

T/F: Some amino acids are manufactured by the body and others must be obtained in the foods we eat.

a)

True

b)

False

35.

T/F: All species have their own unique amino acids that make up their proteins.

a)

True

b)

False

36.

What is the difference between one protein and the next?

a)

The length, type of amino acids, and order of the amino acid sequence

b)

Only the length of the amino acid sequence.

c)

Only the order of the amino acid sequence.

d)

Only the type of amino acids in sequence.

37.

Where are proteins manufactured in the cell?

a)

Nucleus

b)

Mitochondria

c)

Ribosomes

d)

Cell Membrane

38.

Which of the following is NOT part of the structure of a ribosome?

a)

Two protein subunits; a large subunit and a small subunit.

b)

rRNA

c)

nucleotides

39.

The type of RNA that plays an important role in the structure of a ribosome.

a)

mRNA

b)

pre-mRNA

c)

tRNA

d)

rRNA

40.

Which of the following best describes the role of a tRNA?

a)

tRNA is a copy of the gene sequence taken from DNA

b)

tRNA plays a role in the structure of a ribosome

c)

tRNA molecules transfer specific amino acids to the ribosome during translation

d)

tRNA replicates DNA

41.

There are many different tRNA molecules and each carries a specific amino acid. How does one know which amino acid is carried by a tRNA?

a)

It is random

b)

It is based on the promoter sequence on tRNA

c)

It is based on the anticodon sequence on the tRNA

d)

It is based on the codon sequence on the tRNA

42.

During translation, the mRNA codons match up to complementary _____ on tRNA

a)

codons

b)

anticodons

c)

amino acids

d)

nucleotides

43.

(Use your chart in your notes...)

What amino acid does the codon sequence "UCG" code for?

a)

Phe

b)

Tyr

c)

Ser

d)

Ala

44.

(Use your chart in your notes...)

What amino acid does the codon sequence "GCG" code for?

a)

Phe

b)

Tyr

c)

Ser

d)

Ala

45.

What is a "start codon"?

a)

A codon sequence in mRNA that signifies the starting point of translation

b)

Signifies the start of a gene sequence on DNA

c)

An enzyme that starts transcription

d)

An enzyme that starts replication

46.

Codons are (#) ___ bases long

a)

2

b)

3

c)

4

d)

5

47.

The start codon sequence is...

a)

AUG

b)

CCC

c)

GUA

d)

UUU

48.

What causes the end of translation?

a)

A terminator sequence

b)

A stop codon

c)

A promoter sequence

d)

An anticodon

49.

How many codons are in the following mRNA sequence?

AUG CCG GCA ACA

a)

1

b)

12

c)

4

d)

8

50.

How many amino acids would be found in a protein produced with the following mRNA code? (Use your chart or you will probably get this wrong!)

CCC AUG CCG GCA ACA UAU CGA UGA GAG

a)

6

b)

9

c)

27

d)

8

51.

What is the genetic code?

a)

A chart that shows the relationship between mRNA codon sequences and amino acids.

b)

A code that explains how scientists decoded DNA structure

c)

An explanation for why DNA makes RNA

d)

A law put in place to protect people's genetic privacy.

52.

Which process occurs first in protein synthesis?

a)

Translation

b)

Transcription

53.

During translation, the adjacent amino-acids are linked together by _____bonds.

a)

Hydrogen

b)

Peptide

c)

Codon

d)

Protein

54.

The chain of amino acids linked together during translation

a)

Codon

b)

Pre-Protein

c)

Polypeptide

d)

mRNA

55.

The main difference between a polypeptide and a protein is...

a)

A polypeptide is a linear chain of amino acids that makes up part or the whole of a protein when folded.

b)

A protein is made during transcription and polypeptides are made during translation

c)

Polypeptides are made in the nucleus whereas proteins are made at the ribosomes

d)

There is no difference

56.

The codon "CGU" on mRNA would bind to an anticodon of ___ in tRNA.

a)

CGU

b)

GCA

c)

CGT

d)

GCT

57.

What is the difference between a start codon and a promoter sequence?

a)

A start codon exists on mRNA and signifies the beginning of translation. A promoter is on DNA and is the start of transcription

b)

A start codon exists on DNA and signifies the beginning of transcription. A promoter is on mRNA and is the start of translation

58.

During translation, the ribosome has (#) __sites in which tRNA can bind to the mRNA-Ribosome Complex.

a)

1

b)

2

c)

3

d)

4

59.

Any type of mutation that is caused by only a single nucleotide change.

a)

Deletion Mutation

b)

Point Mutation

c)

Insertion Mutation

d)

Frameshift Mutation

60.

A mutation in which a single nucleotide is wrong. For instance, a "T" gets changed into a "C".

a)

Insertion Mutation

b)

Substitution Mutation

c)

Deletion Mutation

d)

Frameshift Mutation

61.

Silent, Missense, and Nonsense are all forms of ______ mutations

a)

Frameshift mutations

b)

Insertion mutations

c)

Substitution mutations

d)

Deletion mutations

62.

A type of mutation where the nucleotide change did not affect the amino acid produced.

a)

Missense

b)

Nonsense

c)

Silent

d)

Frameshift

63.

The type of mutation in which the nucleotide change affected a single amino acid in the protein sequence.

a)

Silent

b)

Missense

c)

Nonsense

d)

Frameshift

64.

The type of mutation that caused protein synthesis to stop because the nucleotide change created a stop codon.

a)

Silent

b)

Nonsense

c)

Missense

d)

Frameshift

65.

Of the three types of substitution mutations, which one is the most likely to have a serious impact?

a)

Silent

b)

Missense

c)

Nonsense

d)

Frameshift

66.

The type of mutation where a single nucleotide is added to the sequence.

a)

Deletion

b)

Substitution

c)

Nonsense

d)

Insertion

67.

The type of mutation where a single nucleotide is removed from the sequence.

a)

Substitution

b)

Insertion

c)

Deletion

d)

Silent

68.

Which two types of mutations lead to frameshift?

a)

Substitution and Insertion

b)

Deletion and Insertion

c)

Substitution and Deletion

d)

None of the above

69.

Which type of mutation would this be?

Original - AAA GCG ATA CCG

Mutation - TTT GCG ATT CCG

a)

Substitution

b)

Insertion

c)

Deletion

d)

Frameshift

70.

Which type of mutation would this be?

Original - AAA GCG ATA CCG

Mutation - TTT GCG ATA ACC G

a)

Substitution

b)

Insertion

c)

Deletion

d)

Frameshift

71.

Which type of mutation would this be?

Original - AAA GCG ATA CCG

Mutation - TTT CGA TAC CG

a)

Substitution

b)

Insertion

c)

Deletion

d)

Frameshift

72.

What type of mutation might cause a "Pro" amino acid to be made instead of a "Thr" amino acid? The rest of the polypeptide is produced correctly.

a)

Missense

b)

Nonsense

c)

Silent

d)

Frameshift

73.

What type of mutation might cause a "Pro" amino acid to be made instead of a "Thr" amino acid? The rest of the polypeptide is produced correctly.

a)

Missense

b)

Nonsense

c)

Silent

d)

Frameshift