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WorksheetsBlood Banking
Total questions: 86
Worksheet time: 14mins
branch of science deals with study of red cell antigens and antibodies important in transfusion of blood components
Immunology
Serology
Hematology
Immunohematology
Plasma carries erythrocytes, leukocytes and (a)
A clear liquid that carries red blood cells, white blood cells and platelets is called (a)
Haemal system consists of all except
arteries
veins
platelets
capillaries
If you mix type A and type B blood, the red blood cells join together or 'clump'. Is clumping bad?
Yes
No
Refrigerator
Freezer
Proof Box
True or False:
The superior vena cava carries oxygenated blood.
True
False
Blood travels from the left ventricle through this valve when heading to the aorta.
Mitral Valve
Aortic Valve
Pulmonary Valve
Tricuspid Valve
Manual scale
Digital Scale
Mandoline
Which blood vessel carries blood from the heart to the lungs to receive oxygen?
Aorta
Vena Cava
Pulmonary Artery
Pulmonary Vein
In what year was Gel Test Technology developed?
1945
1895
1985
1934
The human heart has ___ chambers.
3
5
4
2
What percentage of human blood is fluid plasma?
30%
55%
75%
Direct Typing's principle is to detect ________ _______ by using patient ______ ______ ______.
Unknown Antigen & Patient Serum
Unknown antibodies & Patient Serum
Unknown Antigen & Patient Red Blood Cells
Unknown Antibodies & Patient Red Cell Suspension
A procedure which is considered as a screening test in blood typing.
Abo typing
Serum Typing
Cell Grouping
Reverse Typing
Procedure used to detect unknown antibodies in the serum using red cell suspension.
Serum Typing
Cell Typing
Blood Typing
Direct Typing
Reagents used in Direct typing are the following except:
Anti-A
Anti-B
Anti-AB
Anti-D
All of the following
There are cases where indirect typing is not required:
Newborns and Young Adults
Young Adults and Adults
Geriatric and Young Adults
Newborns and Geriatric patients
Newborns only
It is the method of choice for rapid or bedside typing, commonly seen used in mass blood donation and medical mission. Used in Direct/forward typing procedure.
Slide Method
Tube Method
Gel Method
All of the Above
It is the method of choice for routine typing. Used in Direct/forward typing and Indirect typing procedure.
Slide Method
Tube Method
Gel Method
All of the Above
An automated method in blood typing. The main advantage of this method is its standardization.
Slide Method
Tube Method
Gel Method
All of the Above
Red blood cell clumping; RBCs form clumps and clumping indicates the presence of LATTICE formation o commonly observed positive reaction in blood typing
Hemolysis
Cytolysis
Hemagglutination Reaction
Clumping or Agglutination
It is a strong hemolytic reaction and strong agglutination reaction
Hemolysis
Cytolysis
Hemagglutination Reaction
Clumping or Agglutination
The cross-bridging or cross-linking of antibodies adjacent to the antigen.
Lattice Formation
Cytolysis
Hemagglutination Reaction
Clumping or Agglutination
A red cell destruction; indication of hemolytic reaction is the release of hemoglobin which would change the serum/anti-sera color into clear red or clear pink
Lattice Formation
Sensitization
Hemolysis
Hemoconcentration
A patient has no reaction in both Anti-A and Anti-B.
Blood type A
Blood type B
Blood type AB
Blood type O
A patient has reactions in both Anti-A and Anti-B.
Blood type A
Blood type B
Blood type AB
Blood type O
A patient has a reactions in Anti-A and no reaction in Anti-B.
Blood type A
Blood type B
Blood type AB
Blood type O
A patient has no reactions in Anti-A and a reaction in Anti-B.
Blood type A
Blood type B
Blood type AB
Blood type O
What is the maximum volume of blood that can be collected from a 10-lb donor, including samples for processing
450 mL
500 mL
525 mL
550 mL
When RBCs are stored, there is a "shift to the left." This means:
Hemoglobin-oxygen affinity increases, owing to an increase in 2 , 3-DPG.
Hemoglobin-oxygen affinity increases, owing to a decrease in 2, 3-DPG.
Hemoglobin-oxygen affinity decreases, owing to a decrease in 2, 3-DPG.
Hemoglobin-oxygen affinity decreases, owing to an increase in 2, 3-DPG.
RBCs can be frozen for:
12 months
1 year
5 years
10 years
One criterion used by the FDA for approval of new preservation solutions and storage containers is an average 24-hour post-transfusion RBC survival of more than:
50%.
60%
65%
75%
what occurs during storage of RBC's?
pH decreases
2,3-DPG increases
ATP increases
plasma K+ decreases
when a recessive trait is expressed:
when a recessive trait is expressed:
2 genes carrying the trait were present
no gene carrying the trait was present
the gene is hemizygous
what is the lowest allowable pH for a platelet component at outdate?
6
6.2
5.9
6.8
which is approved for bacterial detection specific to extending the expiration of apheresed platelets to 7 days?
BacT/ALERT
eBDS
Gram stain
Pan Genera Detection (PGD) test
most common cause of bacterial contamination in platelet products?
incorrect storage temp
environmental contamination during processing
entry of skin plugs into collection bag
T in the donor
When a male possesses a phenotypic trait that he passes to all his daughters and none of his sons, the trait is said to be:
X-linked dominant
X-linked recessive
autosomal dominant
autosomal recessive
When a female possesses a phenotypic trait that she passes to all of her sons and none of her daughters, the trait is said to be:
X-linked dominant
X-linked recessive
autosomal dominant
autosomal recessive
what refers to the effect of an excess amount of antigen present in a test system?
postzone
prozone
zone of equivalence
endzone
refers to the presence of an excess amount of antibody present in a test system
Postzone
Prozone
Zone of equivalence
Endzone
property of antibodies not dependent on the structure of the heavy chain constant region
ability to cross placenta
isotype (class)
ability to fix complement
affinity for antigen
molecules that promote the uptake of bacteria for phagocytosis
opsonins
cytokines
haptens
isotypes
unique confirmation of the antigen that allows recognition by a corresponding antibody
immunogen
epitope
avidity
clone
refers to the net negative charge surrounding red blood cells
dielectric constant
van der waals forces
hydrogen bonding
zeta potential
central dogma of molecular biology
DNA is the genetic material
RNA is the genetic material
DNA is translated to mRNA
proteins are transcribed from mRNA
how many days before a pretransfusion specimen expires?
3 days
7 days
14 days
1 month
how many days must a pretransfusion specimen and donor unit segments be retained post transfusion?
3 days
7 days
14 days
1 month
If a blood type cannot be resolved, what ABO group should be selected for a red blood cell transfusion?
group A
group B
group O
group AB
which antibody specificity is not required in antibody detection tests?
a. K
b. Cw
c. Fya
d. S
A
B
C
D
which is not true rouleaux formation?
mimics agglutination
appears like a stacking of coins
can be seen in the antiglobulin test
can be dispersed by saline
a patients blood type is AB neg, but there are no AB neg red blood cell units available, what donor units could be selected?
O pos
A neg
B pos
all of the above
the major immunoglobulin class of anti-B in a group A individual is:
IgG
IgM
IgA
IgE
IgD
patient cells reacted 4+ with anti A and B, and serum reacted neg with A1 and B cells, what is their blood type?
A
B
AB
O
Ss
what are possible ABO phenotypes of the offspring from the mating of a group A to a group B individual?
A
AB
B
O
All of the Following
what are possible ABO phenotypes of the offspring from the mating of a group A to a group B individual?
A,H,Se
B,H,Se
AB,H,Se
H,Se
what ABO blood group contains the least amount of H substance?
(a)
An example of a technical error that can result in an ABO discrepancy
cell suspension is too heavy
inappropriate volume use
undercentrifugation
None of the following
What type of serological testing does the blood bank technologist perform when determining the blood group of a patient?
Genotyping
Phenotyping
Both genotyping and phenotyping
Polymerase chain reaction
If anti-K reacts 3+ with a donor cell with a genotype KK and 2+ with a Kk cell, the antibody is demonstrating:
Dosage
Linkage disequilibrium
Homozygosity
Heterozygosity
Which genotype(s) will give rise to the Bombay phenotype?
HH only
hh only
HH and Hh
Hh and hh
Meiosis in cell division is limited to the ova and sperm producing four gametes containing what complement of DNA?
1N
2N
3N
4N
Which of the following describes the expression of most blood group antigens?
Dominant
Recessive
Codominant
Codominant
The minimum Hgb concentration in a fingerstick from a male blood donor is:
12.0 g/dL (120 g/L)
12.0 g/dL (120 g/L)
13.5 g/dL (135 g/L)
15.0 g/dL (150 g/L)
Which of the following constitutes permanent rejection status of a donor?
a tattoo 5 months ago
recent close contact with a patient with viral hepatitis
2 units of blood transfused 4 months previously
confirmed positive test for HbsAg 10 yrs. earlier
Prior to blood donation, the intended venipuncture site must be cleaned with a scrub solution of:
hypochlorite
isopropyl alcohol
10% acetone
PVP iodine complex
All donors blood testing must include:
complete Rh phenotype
anti-CMV testing
DAT
serological test for syphilis
During the preparation of Platelet Concentrates from whole blood, the blood should be:
cooled towards 6 C
cooled towards 20-24 C
warmed to 37 C
heated to 57 C
The western blot is a confirmatory test for:
CMV antibody
anti-HIV-1
HbsAg
serum protein abnormality
Cryo AHF, if maintained in the frozen state at -18 C or below, has a shelf life of:
42 days
6 months
12 months
36 months
Once thawed, FFP must be transfused within:
4 hrs.
8 hrs.
12 hrs.
24 hrs.
In the liquid state, plasma must be stored at:
1 - 6 C
22 C
37 C
56 C
Irradiation of a unit of RBC's is done to prevent the replication of donor:
a. granulocytes
b. lymphocytes
c. red cells
d. platelets
A
B
C
D
Plastic bag overwraps are recommended when thawing FFP in a 37 C water bath. because they prevent:
FFP bag from cracking
water from slowly dialyzing across the bag membrane
the entry ports from being contaminated with water
the label from peeling
Which of the following blood components must be prepared within 8 hrs. after phlebotomy:
RBCs
FFP
Frozen rbcs
Cryo AHF
A blood component prepared by thawing FFP at refrigerator temp and removing the fluid portion is:
Plasma Protein Fraction
Cryo AHF
Factor IX Complex
FP24
Upon inspection, a unit of platelets is noted to have visible clots, but otherwise appears normal. the tech should:
issue without concern
filter to remove clots
centrifuge to express off the clots
quarantine for gram stain and culture
Which of the following is proper procedure for preparation of platelets from Whole Blood:
light spin followed by hard spin
light spin followed by 2 hard spins
2 light spins
hard spin followed by a light spin
The linked HLA genes on each chromosome constitutes a (an):
allele
trait
phenotype
haplotype
A blood donor has the genotype: hh, AB. what is his RBC phenotype?
A
B
O
AB
Given the following typing results, what is the donors racial ethnicity:
Le(a-b-)
Fy(a-b-)
Js(a+b+)
African American
Asian American
Native American
Caucasian
In an emergency situation, Rh-neg. red cells are transfused into a Rh-pos person of the genotype CDe/CDe. the first antibody most likely to develop is:
anti-c
anti-d
anti-e
anti- E
The red cells of a nonsecretor will most likely type as:
Le(a-b-)
Le(a+b+)
Le(a+b-)
Le(a-b+)
Which of the following phenotype will react with anti-f:
rr
R1R1
R2R2
R1R2
A women types as Rh-pos. She has an anti-c titer of 32 at AHG. Her baby has a negative DAT and is not affected by HDFN. What is the fathers most likely Rh phenotype.
rr
r"r
R1r
R2r
