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Unit 5: Protein synthesis, Mutations, and Gene Expression Review

Total questions: 92

Worksheet time: 1hrs 27mins

Name
Class
Date
1.

Which organelle is the location where protein is made?

a)

Ribosome

b)

Nucleus

c)

Cytoplasm

d)

Nucleotide

2.

During transcription, this type of ribonucleic acid is produced

a)

tRNA

b)

mRNA

c)

rRNA

d)

dRNA

3.

When these bond together, they form a protein

a)

Amino Acids

b)

Peptide Bonds

c)

Ribose

d)

Nucleotides

4.

mRNA is made during this process

a)

Translation

b)

Transcription

c)

Replication

d)

Delivery

5.

Which of the following is the complementary mRNA sequence to this DNA strand: AACTGAA

a)

UUGACUU

b)

TTGACTT

c)

AACTGAA

d)

AACUGAA

6.
What is the term for a three-nucleotide sequence that codes for an amino acid?
a)

DNA triplet

b)
codon
c)

tRNA

d)

anti-codon

7.
The process to go from DNA to mRNA is _______
a)
translation
b)
transcription
c)
replication
8.
The process to go from mRNA to a protein is called ____
a)
transcription
b)
rRNA
c)
replication
d)
translation
9.
Genetic info flows in one direction. Which best represents this flow?
a)
DNA-protein-RNA
b)
Protein-RNA-DNA
c)
RNA-protein-DNA
d)
DNA-RNA-protein
10.
What is the location in the cell for transcription?
a)
nucleus
b)
cytoplasm
c)
ribosome
d)
mitochondria
11.

In what process are proteins synthesized?

a)

Transcription

b)

Translation

c)

DNA Replication

d)

Mitosis

12.

Which organelle contains rRNA and reads the mRNA to synthesize a protein?

a)

Ribosome

b)

Nucleus

c)

Cytoplasm

d)

Nucleotide

13.

What brings the amino acids to the ribosome to assemble a protein?

a)
mRNA
b)
tRNA
c)
rRNA
d)

DNA

14.

How many nucleotides code for 1 amino acid?

a)

1

b)

2

c)

3

d)

4

15.

What is the location in the cell for translation?

a)

Cytoplasm

b)

Nucleus

c)

Lysosome

d)

Golgi apparatus

16.

In RNA, Adenine (A) pairs with...

a)

T

b)

U

c)

C

d)

G

17.

Which of the following is a characteristic of RNA?

a)

Double stranded

b)

Contains the base Thymine

c)

Can leave the nucleus

d)

Contains the sugar deoxyribose

18.

Which type of RNA is responsible for bringing amino acids to the ribosome?

a)

mRNA

b)

rRNA

c)

tRNA

d)

DNA

19.

What amino acid is coded for by the RNA sequence below?

AGG

a)

Gly

b)

Leu

c)

Arg

d)

Val

20.

Which process is shown?

a)

Replication

b)

Transcription

c)

Translation

d)

Photosynthesis

21.

What type of mutation has occured to the DNA sequence below?

Original DNA: AAC - GTA

Mutated DNA: AAG - TA

a)

Substitution

b)

Deletion

c)

Insertion

d)

Non - sense

22.

Select the DNA sequence below that demonstrates a subsitution mutation.

Original DNA: AAT - GCC

a)

Mutated DNA:

AAT - GGC - C

b)

Mutated DNA:

AAG- CC

c)

Mutated DNA:

ATT - GCC

d)

AAT - TGC - C

23.
The two strands of DNA are held together by:
a)
Hydrogen Bonds
b)
Phosphodiester Bonds
c)
Glycolsyl Bonds
d)
Glycosidic Linkages
24.
RNA contains the sugar
a)
ribose
b)
deoxyribose
c)
glucose
d)
lactose
25.

Transcribe the following DNA strand: CTG AAT

a)

GAC TTA

b)

CTG AAT

c)

GAC UUA

d)

CUG AAU

26.
The two strands of DNA are held together by:
a)
Hydrogen Bonds
b)
Phosphodiester Bonds
c)
Glycolsyl Bonds
d)
Glycosidic Linkages
27.
In a molecule of double-stranded DNA, the amount of Adenine present is always equal to the amount of
a)
cytosine
b)
guanine
c)
thymine
d)
uracil
28.
What determines the code, or information, of a DNA molecule?
a)
the shape (structure) of the nitrogen bases
b)
the order (sequence) of the nitrogen bases
c)
the color of the nitrogen bases
d)
the frequency (number) of nitrogen bases
29.
A process in which DNA has the unique ability to make an exact copy of itself.
a)
Replication
b)
Translation
c)
Transcription
30.
Replicate the following strand of DNA: 
AATCATGGA
a)
AATCATGGA
b)
TTAGTACCT
c)
UUAGUACCU
d)
GGATAUCUA
31.
DNA replication results in two DNA molecules,
a)
each one with two original strands
b)
each one with two new strands
c)
each one with one new strand and one original strand
d)
one with two new strands and the other with two original strands
32.
RNA contains the sugar
a)
ribose
b)
deoxyribose
c)
glucose
d)
lactose
33.

Transcribe the following DNA strand: CTG AAT

a)

GAC TTA

b)

CTG AAT

c)

GAC UUA

d)

CUG AAU

34.
What is the correct amino acid sequence for the mRNA code AUGCCAGUAUGA
a)
Met-Pro-Ala-Val
b)
Met-Pro-Val
c)
Tyr-Gly-His
d)
Tyr-Gly-Arg-His
35.
One difference between DNA and RNA is that RNA....
a)
is double stranded 
b)
contains the base Thymine
c)
contains the base Uracil 
d)
contained the base Guanine
36.
The anti-codon 
a)
contains a sequence the same as the codon
b)
contains a sequence complementary to the codon 
c)
contains the base thymine
37.
tRNA is involved in
a)
carrying amino acids 
b)
carrying ribosomes
c)
carrying glucose
d)
carrying lipids
38.
Which organelle is DNA usually found in?
a)
cell membrane
b)
vacuole
c)
chloroplast
d)
nucleus
39.
Which process is happening in this picture?
a)
Transcription
b)
Translation
c)
Replication
40.
Which of the following molecules is created during TRANSCRIPTION?
a)
Protein
b)
DNA
c)
mRNA
d)
tRNA
41.
Which of the following molecules is created during TRANSLATION?
a)
Protein
b)
DNA
c)
mRNA
d)
tRNA
42.
What is the three base sequence of mRNA that codes for a single amino acid?
a)
Anticodon
b)
Codon
c)
Protein
43.
DNA has a _____________ structure. 
a)
double helix
b)
single strand
c)
ring 
d)
chain
44.
Which of the following units are repeatedly joined together to form a strand of DNA? (This is the MONOMER of DNA.) 
a)
amino acids
b)
nucleotides
c)
fatty acids
d)
polysaccharides
45.

Which of the following make up a nucleotide?

a)

Sugar, phosphate, and base

b)

Sugar, nitrate, and base

c)

Lipid, phospate, and sugar

d)

Protein, phosphate, and base

46.

What mutation has occurred here?

T-G-A-C-C-A

T-G-A-G-C-A

a)

Substitution

b)

Deletion

c)

Insertion

d)

Frameshift

47.

Which of the following would result in a frameshift mutation?

a)

Insertions only

b)

Substitution only

c)

Deletion only

d)

Insertions and Deletions

48.

DNA molecule segment is : TTACGCAAG

The mutated DNA segment is TTCGCAAG. This is an example of ___ mutation.

a)

Substitution

b)

Deletion

c)

Insertion

d)

Inversion

49.

A mutation is defined as:

a)

A change in the cell's structure

b)

Anything that changes in an embryo

c)

Any change in the physical features of a human

d)

A change in the DNA sequence

50.

ATTTGAGCC- Original

ATTGAGCC - Mutated

The example above is an example of a

a)

Insertion- Frameshift

b)

Deletion- Substitution

c)

Deletion -Frameshift

d)

All of the above

51.

What mutation has occurred here?

T-G-A-C-C-A

T-G-A-G-C-A

a)

Substitution

b)

Deletion

c)

Insertion

d)

Frameshift

52.

Why are insertion and deletion (frameshift) mutations so harmful?

a)

They change all of the codons from the mutation on down the line, which changes the amino acid sequence

b)

They insert things that an organism doesn't need.

c)

They often delete things that organisms need.

d)

Insertion and deletions are not any more harmful than substitution mutations.

53.

Identify the DELETION mutation form the following:

ATG CCA AAT

a)

ATG TCA AAT

b)

ATG CCT AAA T

c)

ATC CA AT

d)

ATG CCA AAT

54.

Which mutation will cause translation to stop?

a)

Mutations 1 and 3 only

b)

Mutation 1 only

c)

Mutation 2 only

d)

Muations 1, 2, 3

55.

Which type of mutation does the model demonstrate?

a)

Deletion

b)

Substitution

c)

Insertion

d)

Translocation

56.

A substitution mutation that has no effect

on amino acids sequence

a)

Insertion Mutation

b)

Translocation

c)

Silent Mutation

d)

Deletion Mutation

57.

A nucleotide base is inserted or deleted shifting the entire DNA sequence. Entire protein will be changed.

a)

Substitution Mutation

b)

Silent Mutation

c)

Frameshift Mutation

d)

Translocation

58.

A frameshift mutation where a nucleotide base

is removed from the DNA sequence.

a)

Deletion Mutation

b)

Substitution Mutation

c)

Translocation

d)

Silent Mutation

59.

A frameshift mutation where a nucleotide base is added

to the DNA sequence

a)

Insertion Mutation

b)

Deletion Mutation

c)

Substitution Mutation

d)

Chromosomal Mutation

60.

Mutations that involve parts of or all of

a chromosome

a)

Replication

b)

Deletion Mutation

c)

Chromosomal Mutation

d)

Transcription

61.

Which of the following would result in a frameshift mutation?

(More than one correct answer)

a)

Insertions

b)

Substitutions

c)

Deletions

62.

What are the two steps in protein synthesis? (Hint: C-->L)

a)

translation

b)

transcription

c)

codon

d)

anticodon

63.

The Himalayan rabbit's habitat has cold, snowy winters and mild summers. The body is typically covered in white fur except for the nose, feet, tail, and ears, which are covered in black fur.

A scientist shaved an area of white fur on the back of a Himalayan rabbit and placed an ice pack over the shaved area . The shaved area grew black fur.

Which of these best explains why the hair that grew back where the Ice pack was placed was black and not white?

a)

The white hair mutated to black hair as the rabbit's body temperature decreased.

b)

The coat color changed from white to black with the age of the rabbit.

c)

The genes for black hair were activated by specific temperatures.

d)

White hair only grows during certain times of the year.

64.

CRISPR-Cas9 is a genetic modification technique that edits parts of the genome of an organism . Using this technique scientists can add, remove, or modify sections of the DNA sequence.

How can scientists use this technique to control gene expression?

a)

By determining the number of chromosomes in an organism

b)

By identifying how closely related one individual is to another

c)

By calculating the number of genes different organisms produce

d)

By activating or deactivating specific genes

65.

What is gene expression?

a)

The process by which information from a gene is used to create a functional product

b)

Large molecules made up of chains of amino acids that perform various functions

c)

To make a written or typed copy of something, in this case, DNA into RNA

d)

To control or manage something, in this case, the process of gene expression

66.

What are proteins?

a)

The process by which information from a gene is used to create a functional product

b)

Large molecules made up of chains of amino acids that perform various functions

c)

To make a written or typed copy of something, in this case, DNA into RNA

d)

To control or manage something, in this case, the process of gene expression

67.

What does it mean to transcribe?

a)

The process by which information from a gene is used to create a functional product

b)

Large molecules made up of chains of amino acids that perform various functions

c)

To make a written or typed copy of something, in this case, DNA into RNA

d)

To control or manage something, in this case, the process of gene expression

68.

What is the role of gene expression in multicellular organisms?

a)

To make sure that each cell has the right proteins for its job

b)

To conserve energy and space in our cells

c)

To determine when and how our genes make proteins

d)

To regulate how much protein is made

69.

How is gene expression regulated?

a)

By turning the gene on or off

b)

By controlling how much protein is made

c)

By transcribing DNA into RNA

d)

By making a written or typed copy of something

70.

What is the importance of gene expression for all living things?

a)

To make sure that each cell has the right proteins for its job

b)

To conserve energy and space in our cells

c)

To determine when and how our genes make proteins

d)

To help organisms adapt to their environment and respond to changes

71.

What is the role of gene expression in the development of different cell types in multicellular organisms?

a)

To make sure that each cell has the right proteins for its job

b)

To conserve energy and space in our cells

c)

To determine when and how our genes make proteins

d)

To play a role in the development of different cell types

72.

Cell differentiation is critical during embryonic development. The process of cell differentiation results in the production of many different kinds of specialized cells. This process is most directly influenced by

a)

DNA

b)

Lipids

c)

Carbohydrates

d)

ATP

73.

As a fertilized egg divides, the cells differentiate because they

a)

have different sets of DNA passed on to the daughter cells

b)

have different sets of genes activated in the daughter cells

c)

have mutations that cause different genes to appear in the daughter cells

d)

randomly assort the chromosomes into different daughter cells

74.

When gene expression occurs

a)

A gene is mutated with either an insertion or deletion

b)

The gene is removed from the genotype in that cell

c)

The gene is passed on to the daughter cells during mitosis

d)

The gene is activated and used in protein synthesis

75.

Which reason explains why nerve cells function differently than muscle cells?

a)

In nerve cells all the genes are expressed.

b)

In muscle cells all the genes are expressed.

c)

In both kinds of cells the same genes are expressed.

d)

In both kinds of cells different genes are expressed.

76.

How can environmental factors affect gene expression?

a)

a) By modifying DNA sequences

b)

b) By altering how a gene is expressed.

c)

c) By directly changing gene function

d)

d) None of the above

77.

Environmental factors can influence the regulation of gene expression.

a)

True

b)

False

78.

Gene expression is solely determined by genes and is not impacted by the environment.

a)

True

b)

False

79.
What process is going on in this photo? 
a)
Transcription 
b)
Translation 
c)
Replication 
d)
All the above 
80.
The diagram shows the process of
a)
Transcription
b)
Translation
c)
Replication
d)
Mitosis
81.
What is occurring in this picture?
a)
Translation
b)
Replication
c)
Translocation
d)
Transcription
82.
What is the correct amino acid sequence for the mRNA code AUGCCAGUAUGA?
a)
 Met-Pro-Val-Stop
b)
Met-Pro-Arg-Stop
c)
 Tyr-Gly-His
d)
Tyr-Gly-Arg-His
83.
What amino acid is represented by the codon CAG?
a)
Aspartic Acid
b)
Histidine
c)
Glutamine
d)
Methionine
84.
What is the correct amino acid for the following codon:
 CAA
a)
Arg
b)
Met
c)
Gln
d)
Val
85.
A certain kind of butterflies produces red pigment in summer but blue in winter. This is probably due to...
a)
polymerase becoming ligase
b)
three or more copies of the same chromosomes
c)
regulation of gene expression
d)
new viruses in new locations
86.
Stem cells are
a)
cells that grow uncontrollably
b)
undifferentiated and can be any type of cell
c)
never go through cell division
d)
only found in embryos
87.
Which best explains why muscle cells are different from blood cells?
a)
Muscle cells are produced by the brain, but blood cells are produced by the heart. 
b)
Different genes are activated in muscle cells than in blood cells. 
c)
Muscles cells experience different environmental influences than blood cells. 
d)
A mutation occurs during the development of muscle cells but not in blood cells. 
88.
What is cell differentiation?
a)
Process by which cells produce more cells
b)
Process by which cells become specialized
c)
Process by which cells become unspecialized
d)
Process by which cells die
89.

Cells differentiate to perform different functions because

a)

all genes are turned on inside that cell

b)

all genes are turned off inside that cell

c)

different genes are turned on inside that cell

d)

different genes are turned on or off inside that cell

90.

During the process of differentiation

a)

all sections of DNA are activated to determine the structure of a body cell

b)

ONLY ONE section of DNA are deactivated to determine the structure of a body cell

c)

only specific sections of DNA sequence are activated to determine the structure and functions of a body cell

91.

There are about 200 cells in the human body. All these cells have the same DNA. True or False?

a)

True

b)

False

c)

maybe

d)

it depends upon the type

92.

So why do stomach cells function differently than skin cells?

a)

They have different DNA.

b)

Different types of cells simply use different genes contained in the DNA.