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AP Biology 6.1-6.4)

Total questions: 71

Worksheet time: 36mins

Name
Class
Date
1.

What is the function of the ribosomes? 

a)

ATP Synthesis

b)

Digestion

c)

Protein Synthesis

d)

Storage

2.

Transcription & Translation are simultaneously completed in a prokaryote 

a)

True

b)

False

3.

Which describes initiation of translation? 

a)

mRNA binds to tRNA with start codon

b)

mRNA binds to tRNA small subunit

c)

tRNA binds to rRNA with start codon

d)

tRNA binds to Methionine

4.

What is the start codon?

a)

AUG

b)

GUA

c)

TAC

d)

UAC

5.

One codon codes for multiple amino acids....

a)

True 

b)

False

6.

One amino acid is coded by multiple codons...

a)

True

b)

False

7.

What does AGU code for?

a)

Arg

b)

Leu

c)

Phe

d)

Ser

8.

Prokaryotes can synthesize human insulin...

a)

True 

b)

False

9.

Which is not a stop codon?

a)

UAA

b)

UAG

c)

UGA

d)

UGG

10.

What is added when the stop codon is reached

a)

Amino Acid

b)

ATP

c)

Stop Codon

d)

Water

11.

What is translation?

a)

Synthesize DNA under direction of DNA

b)

Synthesize RNA under direction of DNA

c)

Synthesize polypeptides

under direction of DNA

d)

Synthesize polypeptides

under direction of RNA

12.

Where does translation take place?

a)

Cytosol

b)

Golgi Bodies

c)

Nucleus

d)

Ribosome

13.

What is the function of the A site on the ribosome?

a)

Adds the new amino acids

b)

Attached the new amino acids to the polypeptide

c)

Location where adenine pairs with uracil

d)

Location where the empty tRNA leaves the ribosome

14.

What is the function of the P site on the ribosome?

a)

Holds the growing polypeptide

b)

Holds phosphorylated polypeptide

c)

Site that binds to the primary structure of a polypeptide

d)

Site where the phosphate group binds

15.

How many nucleotides make up a codon?

a)

1

b)

2

c)

3

d)

4

16.

What amino acid has a codon of GAC?

a)

Asn

b)

Asp

c)

Glu

d)

Gly

17.

Free ribosomes and bound ribosomes are the same.

a)

True

b)

False

18.

Which direction is DNA read for DNA replication?

a)

3' -> 5’

b)

5' -> 3’

c)

C terminus to N terminus

d)

N terminus to C terminus

19.

Which direction is DNA synthesized in DNA replication?

a)

3' -> 5’

b)

5' -> 3’

c)

C terminus to N terminus

d)

N terminus to C terminus

20.

How is DNA replicated?

a)

Conservative

b)

Dispersive

c)

Lagging

d)

Semiconservative

21.

Enzymes responsible for sealing phosphodiester linkage

a)

Helicase

b)

Ligase

c)

Polymerase

d)

Topoisomerase

22.

Enzymes responsible for relieve strand of double helix

a)

Helicase

b)

Ligase

c)

Polymerase

d)

Topoisomerase

23.

Enzymes responsible for breaking H bonds between strands

a)

Helicase

b)

Ligase

c)

Polymerase

d)

Topoisomerase

24.

Enzymes responsible for synthesis of new DNA

a)

Helicase

b)

Ligase

c)

Polymerase

d)

Topoisomerase

25.

DNA polymerase can start replication independently 

a)

True

b)

False

26.

DNA is...

a)

Antiparallel

b)

Parallel

27.

Which enzyme connects the Okazaki fragments (lagging)

a)

Helicase

b)

Ligase

c)

Polymerase

d)

Topoisomerase

28.

What is at the 5’ end of DNA?

a)

Hydrogen

b)

Hydroxyl

c)

Nitrogenous Base

d)

Phosphate

29.

What is at the 3’ end of DNA?

a)

Hydrogen

b)

Hydroxyl

c)

Nitrogenous Base

d)

Phosphate

30.

Describe the directionality of DNA

a)

Antiparallel

b)

Parallel

c)

Perpendicular

d)

Single Stranded 5’ to 3’

31.

What is the enzyme responsible for breaking hydrogen bonds between nitrogenous bases?

a)

DNA polymerase

b)

Helicase

c)

Ligase

d)

Primase

32.

What enzyme is responsible for synthesizing RNA start?

a)

DNA polymerase

b)

Helicase

c)

Ligase

d)

Primase

33.

What enzyme is responsible for making the new DNA strand?

a)

DNA polymerase

b)

Helicase

c)

Ligase

d)

Primase

34.

Which direction is DNA read?

a)

3’ to 5’

b)

5’ to 3’

c)

Right to Left

d)

Left to Right

35.

Which direction is DNA synthesized?

a)

3’ to 5’

b)

5’ to 3’

c)

Right to Left

d)

Left to Right

36.

Which strand is formed continuously into the replication fork?

a)

Lagging strand

b)

Leading strand

37.

Which strand is formed discontinuously away from the replication fork?

a)

Lagging strand

b)

Leading strand

38.

Lagging strand is made 3’ to 5’ and leading strand is made 5’ to 3’.

a)

True

b)

False

39.

Which RNA functions as site of protein synthesis?

a)

mRNA

b)

rRNA

c)

tRNA

40.

Which RNA functions to bring amino acids to the ribosome?

a)

mRNA

b)

rRNA

c)

tRNA

41.

Which RNA is the transcript from DNA template?

a)

mRNA

b)

rRNA

c)

tRNA

42.

Which RNA has an anticodon that pairs with codon?

a)

mRNA

b)

rRNA

c)

tRNA

43.

Which RNA has the codons sequence for translation?

a)

mRNA

b)

rRNA

c)

tRNA

44.

Which enzyme is responsible for transcription?

a)

Ligase

b)

Primase

c)

RNA Polymerase

d)

Transcriptase

45.

In transcription, which direction is DNA read?

a)

3' to 5’

b)

5' to 3’ 

c)

C terminus to N terminus

d)

N terminus to C terminus

46.

In transcription, which direction is RNA made?

a)

3' to 5’

b)

5' to 3’ 

c)

C terminus to N terminus

d)

N terminus to C terminus

47.

Function of 5' Cap...

a)

Add phosphates to the RNA

b)

Provide ATP for transcription

c)

Protect from hydrolytic enzymes

d)

Site of ribosome binding 

48.

Function of Poly A tail...

a)

Add phosphates to the RNA

b)

Provide ATP for transcription

c)

Protect from hydrolytic enzymes 

d)

Site of ribosome binding 

49.

What is the process of transcription?

a)

Synthesizing DNA under the direction of DNA

b)

Synthesizing DNA under the direction of RNA

c)

Synthesizing RNA under the direction of DNA

d)

Synthesizing RNA under the direction of RNA

50.

What type of virus will violate the central dogma?

a)

Bacteriophage

b)

DNA virus

c)

Retrovirus

d)

All of the above

51.

What enzyme is responsible for transcription?

a)

DNA polymerase

b)

Helicase

c)

Primase

d)

RNA polymerase

52.

Which strand is read for transcription?

a)

3’ to 5’ coding strand

b)

5’ to 3’ coding strand

c)

3’ to 5’ noncoding strand

d)

5’ to 3’ noncoding strand

53.

Which direction is RNA synthesized?

a)

3’ to 5’

b)

5’ to 3’

54.

What is the function of the

poly A tail?

a)

Binds to the promoter region

b)

Decrease degradation by hydrolytic enzymes

c)

Remove noncoding information

d)

Site of ribosome binding

55.

What is the function of the 5’ cap?

a)

Binds to the promoter region

b)

Decrease degradation by hydrolytic enzymes

c)

Remove noncoding information

d)

Site of ribosome binding

56.

What is the primary source of genetic information?

a)

Carbohydrates

b)

DNA/RNA

c)

Lipids

d)

Proteins

57.

Prokaryotic DNA is...

a)

Double stranded and circular

b)

Double stranded and linear

c)

Single stranded and circular

d)

Single stranded and linear

58.

Eukaryotic DNA is...

a)

Double stranded and circular

b)

Double stranded and linear

c)

Single stranded and circular

d)

Single stranded and linear

59.

All cells have plasmids?

a)

True

b)

False

60.

Plasmids can provide genetic variation to prokaryotes?

a)

True

b)

False

61.

In RNA, adenine pairs with...

a)

Cytosine

b)

Guanine

c)

Thymine

d)

Uracil

62.

In DNA, adenine pairs with...

a)

Cytosine

b)

Guanine

c)

Thymine

d)

Uracil

63.

In RNA or DNA, cytosine pairs with...

a)

Adenine

b)

Guanine

c)

Thymine

d)

Uracil

64.

What is a purine?

a)

Carbohydrate with a single ring

b)

Carbohydrate with a double ring

c)

Nitrogenous base with a single ring

d)

Nitrogenous base with a double ring

65.

Which bases are purines?

a)

Adenine and Cytosine

b)

Adenine and Guanine

c)

Cytosine and Guanine

d)

Cytosine and Thymine

66.

What is a pyrimidine?

a)

Carbohydrate with a single ring

b)

Carbohydrate with a double ring

c)

Nitrogenous base with a single ring

d)

Nitrogenous base with a double ring

67.

Which bases are pyrimidines?

a)

Adenine and Cytosine

b)

Adenine and Guanine

c)

Cytosine and Guanine

d)

Cytosine and Thymine

68.

Contrast shape of DNA between prokaryotes and eukaryotes.

a)

Eukaryotes have circular and prokaryotes have linear DNA

b)

Prokaryotes have circular and eukaryotes have linear DNA

69.

Contrast amount of DNA between prokaryotes and eukaryotes.

a)

Eukaryotes have multiple DNA strands while prokaryotes have one DNA strand

b)

Prokaryotes have multiple DNA strands while eukaryotes have one DNA strand

70.

Which organism has plasmids?

a)

Bacteria (prokaryotes)

b)

Yeast (eukaryotes)

c)

Both bacteria and yeast

71.

DNA is more stable than RNA

a)

True

b)

False

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