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q2 biokem

Total questions: 70

Worksheet time: 35mins

Name
Class
Date
1.

O2 can diffuse through the membrane of alveoli and the endothelium of capillary blood vessel because of

a)

the high affinity of o2 to oxygen carrier within erythrocyte

b)

the difference of partial pressure of o2 within alveoli and blood

c)

the molecular weight of o2 molecule which is very small

d)

the solubility of o2 in the blood

e)

the affinity of o2 with the protein in the blood

2.

which of the following enzymes related to digestion is secreted by salivary glad?

a)

trypsin

b)

enterokinase

c)

lactase

d)

pepsin

e)

amylase

3.

the purpose of metabolism of xenobiotics is

a)

to increase their fat solubility

b)

to decrease their ph

c)

to increase their surfase tension

d)

to decrease their affinity to protein

e)

to increase their water solubility

4.

the main lipid component of the lung surfactant is

a)

cholesterol

b)

dipalmityl lecithin

c)

triacyglycerol

d)

arachidonic acid

e)

sphingomyelin

5.

hepatic disease leads to major elevation of the blood level of which one of the following substances?

a)

heme

b)

bile acid

c)

conjugated bilirubin

d)

biliverdin

e)

unconjugated bilirubin

6.

which one of the following organs is most involved in the metabolism of xenobiotics?

a)

lung

b)

kidney

c)

lymphoid glands

d)

liver

e)

spleen

7.

which one of the following organs secretes cholesterol esterase?

a)

stomach

b)

pancreas

c)

spleen

d)

liver

e)

gall bladder

8.

insulin hormone contains two polypeptide chains that are linked together through which kind of bonding?

a)

disulfide

b)

glycoside

c)

hydrogen

d)

peptide

e)

ester

9.

the chloride shift is the exchange of chloride ion with

a)

co2

b)

o2

c)

bicarbonate ion

d)

na ion

e)

k ion

10.

which one of the following organs synthesizes enterokinase?

a)

intestine

b)

gall bladder

c)

liver

d)

kidney

e)

pancreas

11.

hypoventilation is a physiological mechanism to

a)

lower [co2] in the blood and increase blood ph

b)

raise [co2] in the blood and decrease blood ph

c)

lower [co2] in the blood and decrease blood ph

d)

raise [co2] in the blood and increase blood ph

e)

lower [co2] in the blood and increase bicarbonate

12.

most of the water from the consumed food is absorbed in the

a)

duodenum

b)

ileum

c)

gaster

d)

colon

e)

jejenum

13.

a 38 year old woman is found to have an obstructing gallstone in the common bile duct. what is the impact of this condition?

a)

increased recycling of bile salts

b)

increased absorption of cholesterol from the intestine

c)

decreased excretion of protein in the feces?

d)

increased digestion of carbohydrate in the intestine

e)

increased excretion of fat in the feces

14.

vitamin b6 deficiency would be expected to result in the inhibition of

a)

phorphobilinogen deaminase

b)

ala synthase

c)

uroporphyrinogen decarboxylase

d)

ala dehydratase

e)

ferrochelatase

15.

the major mechanism of reaction in phase 1 of metabolism of xenobiotics is

a)

conjugation

b)

hydroxylation

c)

carboxylation

d)

oxidation

e)

deamination

16.

ammonia in colon is the product of putrefaction and fementation by microorganisms from:

a)

protein

b)

starch

c)

triacylglycerol

d)

cholesterol

e)

fatty acid

17.

which statement is true concerning the intestinal brush border membrane?

a)

alpha amylase is secreted by brush border membrane

b)

enterokinase is required for the absorption of glucose

c)

sucrase is only found in the brush border membrane

d)

maltose crosses the brush border membrane

e)

bile salt is required for the absorption of glucose

18.

the normal ph of the blood occurs if the ratio [BHCO3] and [H2CO3] is

a)

15

b)

20

c)

5

d)

10

e)

25

19.

one of the characteristics of porphrin is

a)

is it a hemoprotein

b)

is it an amphoter

c)

it contains Zn

d)

it is a colorless substance

e)

is it a component of vitamin B1

20.

which of the following organs is the site of procarboxypeptidase

a)

liver

b)

stomach

c)

pancreas

d)

gallbladder

e)

spleen

21.

in what state are saturated fatty acids found at room temperature?

a)

gas

b)

vapour

c)

liquid

d)

solids

e)

condensed

22.

biosynthesis of heme requires which one of the following substances?

a)

glutamic acid

b)

propionyl coa

c)

succinyl coa

d)

ferric ion

e)

acetyl coa

23.

mostly digestive rpoduct are processed thru a metabolic pathway into a common product namely

a)

pyruvic acid

b)

glucose 6 phosphate

c)

atp

d)

acetyl coa

e)

fructose 6-phosphate

24.

which of the following enzymes has autocatalytic characteristic?

a)

pepsin

b)

lipase

c)

amylase

d)

cholesterol esterase

e)

enterokinase

25.

udp glucuronyltransferase participates in the conjugation process of bilirubin in order to make it

a)

water soluble and directly enter the blood system

b)

less soluble in water for easy storage in gall bladder

c)

less soluble in water to protect from oxidation

d)

water soluble and secreted into the bile

e)

water soluble and directly secreted into the intestinum

26.

which of the following substances is the substrate of lipase?

a)

arachidonate

b)

palmitate

c)

prostaglandin

d)

cholesterol

e)

tryacylglycerol

27.

complex lipids with fatty acid components that bind to sugar are called?

a)

glycolipid

b)

glicerophospholipid

c)

sphingolipid

d)

glucosan

e)

amylopectin

28.

why is hydrochloric acid secretion within the stomach important in digestion?

a)

it is required for the activity of alpha-amylase

b)

it drives secondary active transport of amino acid

c)

it converts pepsinogen to pepsin

d)

it is required for lipid digestion

e)

it stimulates the cleavagee of trypsinogen to trypsin

29.

which of the following substances related to digestion is secreted by liver?

a)

biliverdin

b)

bilirubin

c)

bicarbonate

d)

lipase

e)

bile aced

30.

which of the following cases of acid-base imbalance is present in patients with renal failure?

a)

metabolic acidosis

b)

respiratory alkalosis

c)

metabolic alkalosis

d)

respiratory acidosis

e)

metabolic alkalosis hypokalemia

31.

which one of the following enzymes contain iron porphyrin?

a)

carbonic anhidrase

b)

ferrochalatase

c)

peroxidase

d)

carboxypeptidase

e)

glutaminase

32.

metabolic acidosis occurs in

a)

bronchitis

b)

pnemonia

c)

asthma bronchiale

d)

cushing syndrome

e)

severe diarrhea

33.

which of the following substances contains iron porphyrin?

a)

myoglobin

b)

stercobillinogen

c)

phenylalanine

d)

adenosin

e)

phosphocreatin

34.

which of the following acid-base imbalance is present in patients with uncontrolled diabetes mellitus

a)

respiratoric alkalosis

b)

metabolic alkalosis with hypokalemia

c)

metabolic acidosis

d)

respiratoric acidosis

e)

metabolic alkalosis

35.

edema can occur in hypoalbuminemia which is a complication of

a)

lung disease

b)

severe diarrhea

c)

liver disease

d)

heart disease

e)

severe vomiting

36.

the mechanism of reaction in phase 2 of metabolism of xenobiotics is

a)

hydrolisis

b)

conjugation

c)

dehydrogenation

d)

decarboxylation

e)

reduction

37.

aldose is referred to as a reducing sugar. this means that aldehydes are capable to be oxidized forming

a)

r-cho

b)

r-cooh

c)

r-co

d)

r-o-r

e)

r-oh

38.

the regulatory enzyme of the biosynthesis of porphyrin is

a)

protoporphyrinogen oxidase

b)

uroporphyrinogen decarboxylase

c)

ala synthase

d)

porphobilinogen deaminase

e)

ala dehydratase

39.

during a breathing cycle

a)

gas exhange between the alveoli and the capillary blood can occur at all times

b)

atmospheric water vapour is taken up by the lung

c)

there is net uptake of nitrogen by the blood

d)

the alveolar gases are completely exchanged for atmospheric gases

e)

gas exchange with the capillary blood occurs at the surface of all the airways

40.

the normal color of feces is due to which one of the following substances?

a)

stercobillin

b)

billverdin

c)

billirubin

d)

cholesterol

e)

bile acid

41.

what is the normal range of the blood's ph?

a)

7.50 - 7.43

b)

7.23 - 7.45

c)

7.25-7.50

d)

7.48-7.25

e)

7.35-7.45

42.

the main buffer system in erythrocyte is

a)

h2co3 - bhco3 buffer system

b)

lactate buffer system

c)

phosphate buffer system

d)

albumin buffer system

e)

hemoglobin buffer system

43.

the process of chloride shift occurs in

a)

the wall of alveoli

b)

the membrane of erythrocyte

c)

the membrane of leucocyte

d)

the membrane of enterocyte

e)

the membrane of blood vessel

44.

the concentration of protein in human plasma is important in determining the distribution fluid between blood and tissue. the major protein in human plasma is

a)

laminin

b)

albumin

c)

alpha globulin

d)

gamma globulin

e)

beta globulin

45.

which of the following organs are important in regulating the ph of the blood

a)

liver and spleen

b)

kidney and lung

c)

kidney and liver

d)

lung and liver

e)

liver and muscles

46.

proteins are linear heteropolymers of a-amino acids. alpha carbon of amino acids is carbon number

a)

2

b)

3

c)

5

d)

4

e)

1

47.

hepatic disease leads to major elevation of the blood level of

a)

bile acid

b)

bileverdin

c)

cholesterol

d)

conjugated billirubin

e)

unconjugated billirubin

48.

which one of the following substances is strong acid?

a)

lactic acid

b)

hydrochloric acid

c)

carbonic acid

d)

acetic acid

e)

phosphoric acid

49.

which of the following organs has no role in digestion?

a)

stomach

b)

pancreas

c)

liver

d)

mouth

e)

spleen

50.

amylum is a glucose polymer with bonds connecting atom c numbers

a)

c 1-5

b)

c 1-4

c)

c 1-3

d)

c 1-6

e)

c 1-2

51.

the synthesis of porphyrin requires which one of the following amino acids

a)

glycine

b)

cystine

c)

methionine

d)

glutamic acid

e)

alanine

52.

sucrose is a combination of glucose and fructose. the disaccharide is formed as a result of glycoside bond between atom c numbers

a)

c 1-3

b)

c 1-2

c)

c 1-6

d)

c 1-5

e)

c 1-4

53.

the function of lung surfactant is

a)

to transport the gases into the blood

b)

to increase the affinity of the gases to protein in the circulation

c)

to decrease the solubility of the gases in alveoli

d)

to increase the surface tension between gases and liquid

e)

to decrease the surface tension between gases and liquid

54.

which of the following ions is the major cation in the erythrocyte?

a)

zn ion

b)

ca ion

c)

na ion

d)

k ion

e)

mg ion

55.

a newborn is seen by a doctor with the symptoms of diarrhea everytime the baby feeds. laboratory test indicates a congenital deficiency of enterokinase, the enzyme that normally activates which of the following zymogen?

a)

chymotrypsinogen

b)

procarboxypeptidase

c)

trypsinogen

d)

proelastase

e)

pepsinogen

56.

which of the following ions is the major cation in the extracellular fluid?

a)

mg ion

b)

ca ion

c)

na ion

d)

nh4 ion

e)

k ion

57.

the most important solute for the distribution and retention of body water is

a)

amino acid

b)

protein

c)

urea

d)

inorganic electrolytes

e)

glucose

58.

the transportation of co2 by the blood circulation from the tissue to the lungs is mainly in the form of

a)

physical solution in the blood

b)

carbamino complex with albumin

c)

carbamino complex with hemoglobin

d)

bicarbonate

e)

carbonic acid

59.

dietary tryacylglycerols are absorbed from the intestinal lumen mainly as

a)

fatty acid and 2-monoacyglycerol

b)

fatty acid and glycerol phosphate

c)

fatty acid and 1,2-diacylglycerol

d)

fatty acid and glycerol

e)

fatty acyl-coa and glycerol

60.

what is the principal factor which controls the location and the amount of fluid in the various compartments of the body?

a)

ph

b)

osmotic force

c)

the leucocyte concentration

d)

the erythrocyte concentration

e)

temperature

61.

which of the following cases of acid base imbalance is present in patience with morphine poisoning?

a)

respiratory acidosis

b)

metabolic alkalosis hypokalemia

c)

metabolic alkalosis

d)

metabolic acidosis

e)

respiratory alkalosis

62.

a medical student becomes extremely anxious the night before a biochemistry examination and begins to hyperventilate uncontrollably. what initial effects does hyperventilation have on the student's pco2 and blood ph?

a)

pco2 increases and ph increases

b)

pco2 decreases and ph increases

c)

pco2 increaes and ph decreases

d)

pco2 decreases ph decreases

e)

no effect

63.

which of the following enzymes related to digestion is secreted by the small intenstine?

a)

lipase

b)

carboxypeptidase

c)

amylase

d)

aminopeptidase

e)

cholesterol esterase

64.

unsaturated fatty acid can turn into saturated fatty aced by adding

a)

N

b)

H

c)

O

d)

C

e)

S

65.

which of the following organs serves in regulating the concentration of h2co3 in the blood

a)

kidney

b)

lung

c)

liver

d)

spleen

e)

brain

66.

which of the following organs stores an essential emulsifier or lipids

a)

liver

b)

spleen

c)

stomach

d)

pancreas

e)

gall bladder

67.

how would u describe a nucleic acid molecule?

a)

a polymer of nucleosides

b)

one nucleoside bound ot one nucleotide

c)

binding of 2 nucleotides

d)

binding of 2 nucleosides

e)

a polymer of nucleotides

68.

transport of oxygen by the blood from the lungs to the tissues is carried out by

a)

bicarbonate

b)

carbonic acid

c)

albumin

d)

myoglobin

e)

hemoglobin

69.

which of the following enzymes is an intestinal protease?

a)

rennin

b)

ptyalin

c)

myokinase

d)

trypsin

e)

transaminase

70.

Which of the following statements concerning cytochrome P450 is correct?

a)

It cannot be induced

b)

It is a hemoprotein

c)

It requires vitamin B1 as coenzyme

d)

It catalyse the conyugation of a xenobiotics

e)

It requires NAD as a coenzyme

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