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WorksheetsSemester Two Piestch FInal
Total questions: 169
Worksheet time: 2hrs 49mins
Select those exercises that are most beneficial for a person with DMD.
Biking
Walking
Weightlifting
Swimming
Running
The contractive unit of a muscle is shown below. It is called a (an):
Muscle fiber
Sarcomere
Fascicle
Hypertrophy
The term for muscles decreasing in size after exercising is:
Hyperrtrophy
Atrophy
Dystrophy
Sarcomere
Select the function of proteins from the selections below.
Structure for an organism
Movement & building muscle
Chemical messengers
Immune defense & Transport
Helps with biochemical reactions inside & outside cells
When muscles are not used, they decrease in size. This is known as:
Hypertrophy
Dystrophy
Atrophy
Sarcomere
The correct organization of a muscle from largest to smallest is:
Myofibril - Muscle fiber - Fascicle - Muscle
Muscle fiber - Fascicle - Muscle - Myofibril
Fascicle - Muscle - Muscle fiber - Myofibril
Muscle - Fascicle - Muscle fiber - Myofibril
Which two proteins are important to muscles and muscle contractions?
Actin and myosin
Fascicle and myofibril
Cardiac and skeletal
Skeletal and smooth
Which of the following are types of muscle tissue found in the human body? Select all that apply.
Smooth
Nervous
Cardiac
Connective
Skeletal
Which is true of DMD? Check all that apply.
It is seen more in females than males.
It is seen more in males than females.
The disorder progresses over time.
It is a genetic disorder passed down from one/both parents.
Muscles are divided into large sections known as ____________ which contain smaller muscle fibers within them.
Myofibrils
Fascicles
Sarcomeres
Tendons
Look at the enzyme complex diagram below. Which part of the diagram is the ENZYME-SUBSTRATE COMPLEX?
A
B
C
D
E
What protein filament is being identified by the red arrow below?
Actin
Myosin
Titin
Dystrophin
When a person has two alleles for a trait that are identical (HH, hh), they are said to be ____________ for that trait.
Homozygous
Heterozygous
Carrier
Every normal human has ____ chromosomes. The sex chromosome configuration for a male is ____.
44; XX
44; XY
46; XX
46; XY
2; XY
Look at the enzyme complex diagram delow. Which part of the diagram is the ACTIVE SITE of the enzyme?
A
B
C
D
E
Which of the following is not a protein found in human muscles?
Actin
Myosin
Sarcolemma
Creatine
Dystrophin
How does a person get DMD?
Mutated gene on the Y chromosome usually passed down from the father.
Mutated gene on the X chromosome usually passed down from the mother.
Muatated gene that occurs early in life from an unknown mutagen (anything that causes a mutation).
A person gets DMD from being inactive early in life and never recovers from the disease.
The protein filament shown below by the red arrow is:
Actin
Myosin
Titin
Dystrophin
What is the importance of enzymes to our digestive system?
Enzymes control the temperature for digestion process to occur normally.
Enzymes help with absorption of the molecules into your blood.
Enzymes help speed up the process of breaking down the food.
Enzymes block nutrients from leaving your body.
Look at the enzyme complex diagram below. Which part of the diagram is showing the SUBSTRATES?
A
B
C
D
E
Look at the enzyme complex diagram below. Which part of the diagram is showing the PRODUCTS after the enzyme does its' job?
A
B
C
D
E
What is DMD?
Dytrophy Muscle Dysfuntion
Disabled Muscular Disease
Duchenne Muscular Dystrophy
Dysfunctional Muscle Disease
Which of the following is NOT a function of proteins in our body?
Structural
Contractile
Enzymes
Temperature regulation
Patients with DMD lack which muscle protein?
Actin
Myosin
Creatine
Dystrophin
When a person has two different alleles for a given trait, they are said to be ___________ for that trait.
Homozygous
Heterozygous
Phenotype
Genotype
How are chromosomes inherited?
Each offspring inherits a randon number of chromosomes from each parent.
Male offspring inherit their chromosomes from their mothers.
Female offspring inherit their chromosomes from their fathers.
Each offspring inherits half of their chromosomes from each parent.
How many generations are shwon in the pedigree below?
12
3
4
5
Using letter A and a, what is the genotype of Person 2?
AA
Aa
aa
Person 2 has a child with someone heterozygous for Huntington's Disease. Use a Punnett Square to determine the chance that their offspring woujld have Huntington's Disease.
0%
25%
50%
75%
100%
How is DMD inherited mostly/all by boys?
DMD is autosomal dominant and males typically inherit more dominant alleles than females.
DMD is sex-linked on the Y chromosome and males are the only gender with a Y chromosome.
DMD is sex-linked on the X chromosome and inherit the allele from their carrier mother.
Select all the cell types that are produced from the process shown below.
Hair
Bone
Blood
Sperm
Egg
Select each choice that represents a homozygous genotype.
AA
Bb
cc
DD
Ee
Approximately how many genes do humans have?
10,000
20,000
30,000
40,000
What is a gene?
The entire sequence of human DNA made of A,T,C,G.
A segment of DNA that codes for a specific protein.
A entire condensed strand of DNA.
What process is shown below?
Mitosis
Meiosis
Crossing over
Independent assortment
Using X and Y chromosomes, and letters H and h, what is the genotype of Person 1?
XH Xh
XH XH
XH Yh
Xh Yh
What process is shown below?
Mitosis
Meiosis
Crossing over
Independent assortment
Using letters H and h, what is the genotype of Person 2?
HH
Hh
hh
What type of inheritance pattern is seen in the pedigree below?
Autosomal recessive
Autosomal dominant
Sex-linked recessive
Sex-linked dominant
Purple pea flowers are dominant to white. Select all genotypes that would result in purple pea flowers.
PP
pp
Pp
P
p
Select all the cell types that are produced from the process shown below.
Hair
Bone
Blood
Sperm
Muscle
What type of inheritance pattern is seen in the pedigree below?
Autosomal recessive
Autosomal dominant
Sex-linked recessive
Sex-linked dominant
What percentage of human DNA nucleotides actually code for the production of proteins?
1.5%
99%
98.5%
10%
In guinea pigs, short hair is dominant to long hair. Cross two heterozygous guinea pigs. What percentage of guinea pigs would we expect to have long hair?
25%
50%
75%
100%
What gametes join together and combine chromosomes, the resulting cell is called a (an):
Germline cell
Gamete
Zygote
Allele
Using the Punnett square below, if T = Tall and t = short, what percentage of offspring would we expect to be tall?
100%
75%
25%
3/4
What process in Meiosis is shown below?
Independent assortment
Crossing over
Homologous chromosomes
Female chromosomes
Select the somatic cells below.
Hair
Bone
Blood
Muscle
Sperm
Which image below represents the protein in the whole process?
E
F
G
H
The molecule shown below is:
DNA
mRNA
tRNA
rRNA
The process of making mRNA strand from DNA in the nucleus is called:
Transcription
Translation
Amino acids
Replication
Which base is NOT found on an RNA strand?
A
T
C
G
U
How many different types of amino acids are produces by the human body?
Hundreds and hundreds
99
20
Thousands
Which of the following base sequences is used to determine amino acids inside our cells?
DNA
mRNA
tRNA
GTA
Which base is NOT found on a DNA strand?
A
T
C
G
U
Which image represents the amino acid?
B
E
F
H
What is the correct complimentary base pair for RNA of the choices below?
A - T
A - C
U - A
G - A
What is the molecule shown below?
tRNA
mRNA
Nucleotide
Thymine
What amino acid is coded by the bases AGU?
Arginine
Serine
Lysine
Asparagine
Which of the following is NOT a difference between DNA and RNA?
DNA contains the base Thymine; RNA contains the base Uracil
DNA is double stranded; RNA is single stranded
DNA codes for proteins; RNA codes for carbohydrates
DNA contains the sugar Deoxyribose; RNA contains the sugar Ribose
What amino acid chain is coded by the bases:
GGG UUU CCC AAA
Glycine - Phenylalanine - Proline - Lysine
Glycine - Alanine - Arginine - Methionine
Proline - Lysine - Valine - Leucine
Methionine - Isoleucine - Glutamine - Histidine
There are three types of RNA involved in gene expresson. Which one is NOT an RNA type below?
nRNA
mRNA
tRNA
rRNA
Three bases on a tRNA strand are called a (an):
Codon
Anti-codon
Amino acid
Nitrogen base
Which amino acid sequence is correct for the given bases?
Arginine - Tyrosine - Lysine
Alanine - Methionine - Phenylalanine
Arginine - Asparagine - Lysine
Proline - Isoleucine - Serine
Which image represents the codon?
G
H
I
J
On which RNA strand do we find three letter code words known as "codons"?
nRNA
mRNA
tRNA
rRNA
How many chromosomes does a haploid cell have in comparison to a diploid cell?
Half the amount
Double the amount
Same amount
Zero
Select all the cell types that are produced from the process shown below.
Hair
Bone
Blood
Sperm
Egg
What is a gene?
The entire sequence of human DNA made of A, T, C, G.
A segment of DNA that codes for a specific protein.
An entire condensed strand of DNA.
When gametes join together and combine chromosomes, the resulting cell is called a (an):
Germline cell
Gamete
Zygote
Allele
Select the somatic cells below.
Hair
Bone
Blood
Egg
Muscle
Somatic cells go through the process of ________ to produce new body cells while our reproductive organs go through ________ to produce new sex cells.
DNA replication; Mitosis
Meiosis; Mitosis
Mitosis; Karyotype
Mitosis; Meiosis
Which of the following is an example of a haploid cell?
Blood cell
Muscle cell
Sperm cell
Hair cell
Select all the cell types that are produced from the process shown below.
Hair
Bone
Blood
Muscle
Sperm
Approximately how many genes do humans have?
10,000
20,000
30,000
40,000
What process in Meiosis is shown below?
Independent assortment
Crossing over
Homologous chromosomes
Female chromosomes
How many chromosomes are in a human sperm cell?
46
44
23
2
Select the gametes below.
Ovaries
Sperm
Testes
Eggs
Blood
What process is shown below?
Mitosis
Meiosis
Crossing over
Independent assortment
How are chromosomes inherited?
Each offspring inherits a random number of chromosomes from each parent.
Male offspring inherit their chromosomes from their mothers.
Female offspring inherit their chromosomes from their fathers.
Each offspring inherits half of their chromosomes from each parent.
How many autosomes do we have in each somatic cell?
46
2
44
1
Looking at the karyotype, what gender is this patient?
Male
Female
A mutation that has neither a positive or negative effect on an organism's survival rate is called a (an):
Harmful mutation
Beneficial mutation
Neutral mutation
If the 5th base of the original strand of DNA with bases AATTGAACACATGCGCCC was changed from a G to a C, what type of mutation would this be an example of?
Chromosome
Point
Frameshift
Nondisjunction
Which type of chromosome mutation results in changing the size of the chromosome and causing multiple copies of a gene to occur?
Duplication
Translocation
Nondisjunction
Point
Which type of mutation appears to more likely lead to DMD?
Silent
Missense
Nonsense
Nondisjunction
You have a DNA sequence that codes for a protein and is 126 bases long. A frameshift mutation occurs at the 100th base. How many amino acids will be unaffected in this protein chain and remain in the correct order?
99
35
2
33
The two main types of mutations are:
Gene & Chromosome mutations
DNA & Meiosis mutations
Meiosis & Gene mutations
Chromosome & DNA mutations
If a G were added to the original DNA strand with bases AATTGAACACATGCGCCC after the 3rd base, what type of mutation would this be an example of?
Chromosome
Point
Frameshift
Nondisjunction
Which type of chromosome mutation results in chromosomes not separating correctly and resulting in too many or not enough chromosomes in each sex cell?
Duplication
Translocation
Nondisjuction
Frameshift
What is a mutation?
A disorder
When a person has supernatural powers
Any change in DNA sequence
Anything that causes cancer
A substitution of one DNA/RNA base for another is an example of which type of mutation?
Frameshift
Point
Additon
Deletion
An addition or deletion of a DNA/RNA base causes which type of mutation?
Frameshift
Point
Inversion
Translocation
Which is an example of where mitosis would occur? Select all that apply.
Development of sperm cells
Grass growing
Development of egg cells
Broken bone healing
Formation of new blood cells
When pairing up chromosomes to make a karyotype, which of the following is NOT a characteristic used to determine matching chromosomes?
Length of chromosome
Placement of their centromeres
Location and size of the G-bands
Base pairing sequences
A diagram that shows the number and appearance of chromosomes in a cell is called a (an):
Amino acid
Nucleus
Karyotype
Centromere
Using a scratch sheet of paper, determine which two mRNA sequences below code for the same protein.
mRNA #1: UCG CUA GCG ACC AGU UCA
mRNA #2: AGC CUC GCC ACU CGU AGU
mRNA #3: AGU UUA GCA ACG AGA UCA
mRNA #4: AGC CUA GCC AAC CAU UCC
mRNA #1 & mRNA #2
mRNA #2 & mRNA #3
mRNA 3 & nRNA #4
mRNA #1 & mRNA #4
Are mutations ALWAYS bad?
Yes
No
In the opening video for L1 on DMD, select all choices that are true about the people in the video:
Many were happy and able to perform daily activities
They were all boys
They were all unable to walk and take care of themselves
The disease was different for each individucal
Many were in wheelchairs
In our analogy for what is happening in DMD patients, what structure served as our "boat anchor" attaching from the sarcolemma to the inside of the myofibril?
Actin
Myosin
Dystrophin
Creatine
A decrease in muscle size due to lack of use is:
Hypertrophy
Atrophy
Dystrophy
Dystrophin
Myofibrils are made up of small, contractile units known as:
Muscle fibers
Muscles
Sarcomeres
Flexors
Patients with DMD lack which muscle protein?
Actin
Myosin
Creatine
Dystrophin
Which of the following explanation is best to explain why it is important for a person to consume protein if/when they are actively working out?
Muscles require protein as energy to do the work.
The filaments involved in contractions are made up of proteins.
It helps them breathe easier during workouts.
Protein helps a person sleep better so they recover after workouts.
Which is the best explanation/definition for "dystrophy"?
An increase in muscle size.
A decrease in muscle size due to lack of use.
A decrease in muscle size after direct use.
A temporary increase in muscle size.
What are the two primary proteins involved in a muscle contraction within a sarcomere?
Actin & Titin
Myosin & Dystrophin
Actin & Myosin
Titin & Dystrophin
How does a person get DMD?
Mutated gene on the Y chromosome usually passed down from the father.
Mutated gene on the X chromosome usually passed down from the mother.
Mutated gene that occurs early in life from an unknown mutagen (anything that causes a mutation)
A person gets DMD from being inactive early in life and never recovers from the disease.
After realizing that no antibiotics were working for the second infection, the doctor informed Addie's mother that the bacterial infection was _________ resistant, meaning it was resistant to ALL antibiotics.
MRSA
All
Omni
Pan
Select those reason why The Human Genome Project was so important to science.
Genes that caused diseases were identified
Genetic tests were discovered to identify disorders
Better medicine/treatments were created
While on the life support machine, Addie got a much more serious bacterial infection. The bacteria was:
Stenotrophomonas
MRSA
Methicillin
Stapholococcus
Who get credited for the discovery of DNA in most science books?
Watson & Crick
Rosalind Franklin
Mark Watney
Teddy Sanders
Addie's initial illness was caused by which type of bacterial infection?
E. coli
Strep throat
MRSA
Addie's first symptom that something was wrong was:
A fever
Stomach pain
Vomiting
Hip pain
By the end of the video, Addie was told by doctors that she wasn't a "good candidate" for a lung transplant. Why did doctors say this to her family?
Addie's lungs were as good as the donor lungs.
The lungs were from a younger donor and Addie was too old.
The bacteria in Addie's body would destroy the new lungs.
Her mother's insurance couldn't cover the cost of the surgery.
Select all examples of genetics engineering used in/on organisms.
Glofish used to detect water pollution
Growing foods in large quantities
Growing food that take longer to spoil
Growing foods that have added mutrients
As things worsened from Addie's initial illness, she was put on a machine to help remove carbon dioxide from her blood while replenishing it with oxygen. This machine is known as a/an:
MRSA
ECMO
Antibiotic
Lung transplant
The second bacterial infection came from:
Too many doctors handling Addie without properly sanitizing prior.
The nursing staff.
The tubes of the life support machine.
Leftover bacteria from the initial infection.
During the video, we notice a pattern of Addie getting slightly better, the worse, then slightly better, then worse again and repeating this pattern multiple times. The pattern was most likely caused by:
Doctors providing the incorrect medicine and changing it.
Bacteria becoming resistant to the antibiotics the doctors were giving her.
Addie not comfortably resting and trying to do too much in the hospital.
Too many doctor were trying to help her and their treatments were always different for different doctors.
From the articles, all of the following are mentioned to help stop the spread of MRSA except:
Shower/bathe regularly
Do not share drinks with others
Wash hands with soap/water
Do not share unwashed towels
According to the graph below, which antibiotics are most at-risk of not being effective against resistant strains of bacteria? Check all that apply.
Ampicillin
Penicillin
Bacitracin
Tetracycline
Vancomycin
From our readings, which type of material tested with the highest levels of bacteria?
Metal
Vinyl
Cloth
Rubber
Concrete
Some bacteria can reproduce in 20 minutes. How many of these bacteria would there be from one parent after three hours of time?
128
256
512
1024
What is MRSA?
The name of the antibiotic used to kill bacteria
Methicillin-resistant Stapholococcus aureus
Stenotrophomonas
Millions of Resistant Small Animals
What type of growth curve do we see in the graph?
Logistic
Exponential
Stimulated
Mathematical
According to the study associated with the graph below, what surfaces on the sampled bus/train had the highest likelihood for contracting a bacterial infection?
Under the seats
On the windows
On the floors and seats
On the armrests and handrails
How many MRSA hospitalizations (per 1,000 hospitalizations) were there in the year 2000?
Approx. 3
Approx. 4
Approx. 40
Approx. 400
Based on these numbers below, what is the survival rate if someone contracts an antibiotic-resistant bacterial infection?
5% or less
50% survival rate
90% or less
95% or greater
Risk for contracting MRSA increases in/at all of the following situations EXCEPT:
Crowded areas
Sharing of equipment
Skin to skin contact with others
Athletic facilities
Doing homework in my room
Which of the following is a method by which bacteria reproduce?
Meiosis
Sexual reproduction
Binary fission
Nondisjunction
For one bacterium, how many new cells will it form when it reproduces?
1
2
4
8
In the chart below, what does it mean that a variation of bacteria is "resistant" to antibiotics?
It means that antibiotics work effectively to kill bacteria.
It means that antibiotics do not kill the bacteria.
It means that certain types of antibiotics must be used.
What quadrant of our Petri dish did we place the swab directly from the surface of the area we chose to test at YLHS?
Quadrant A
Quadrant B
Quadrant C
Quadrant D
Which of the following bacteria cells would we expect to increase in number and be most resistant to antibiotics?
Purple
Green
Brown
Red
Which type of cells remember the antigens so the immune system can fight off the pathogen faster?
B-cells
T-cells
Memory cells
Macrophages
Which line of defense would fevers fall into?
1st line of defense
2nd line of defense
3rd line of defense
4th line of defense
Which quadrant of our Petri dish SHOULD have the least amount of bacteria and mold growth?
A
B
C
D
What is the function of the B-cells as part of our last line of defense against the pathogens?
Located and destroy any infected host cell.
Create antibodies to prevent future infections.
Release histamine to create redness & swelling.
To trap pathogens and sweep them out with cilia.
Which quadrant of our Petri dish did we place the swab used to sample our hand after washing/sanitizing after touching the surface of our tested area?
Quadrant A
Quadrant B
Quadrant C
Quadrant D
Which quadrant of our Petri dish served as the control for out experiment?
Quadrant A
Quadrant B
Quadrant C
Quadrant D
Select all the environmental conditions that bacteria reproduce best in.
Warm/hot temperatures
Sunlight
Darkness
Moist
Dry
When a macrophage touches a pathogen, what does it do to the pathogen?
Reproduces with it.
Eats it.
Identifies it.
Makes holes in the cell membrane.
Select the pathogens listed below.
Viruses
Bacteria
Fungus
Parasites
Vaccines
Select all those that are pat of the 1st line of defense for our immune system.
Skin
Mucus
Cilia
Inflammation
T-cells
Which quadrant appears to have the greatest number of bacteria colonies?
A
B
C
D
Which quadrant of our Petri dish did we place the swab used to sample our hand after touching the surface of our tested are but before we washed/sanitized our hand?
Quadrant A
Quadrant B
Quadrant C
Quadrant D
Which of the following is NOT a white blood cell?
Macrophage
T-cells
B-cells
Platelet
Which type of natural selection is occurring when the average/intermediate form of a phenotype is favored in the environment?
Stabilizing selection
Directional selection
Disruptive selection
Various selection
The chart below measures the whiteness of the tail feathers in Juncos. What statement below is the most true?
Females had more whiteness in their tail feathers than males.
UCSD Juncos had more whiteness in their tail feathers than Mt. Laguna Juncos.
Males had less whiteness in their tail feathers than females.
Mt. Laguna Juncos had more whiteness in their tail feathers for both sexed than UCSD Juncos.
From the video The Beak of the Finch, where the Grant's retraced the footsteps of Charles Darwin on the Galapagos Islands, what type of finches were favored after the drought of 1977 and what type of food source was available to help these birds?
Large beak; large seeds
Small beak; small seeds
Medium beak; cactus plants
Which type of natural selection shows one extreme version of a phenotype is favored in the environment?
Stabilizing selection
Directional selection
Disruptive selection
Various selection
The process where organisms with useful traits/adaptations for their environment have a survival advangtage & reproduce with more offspring to pass on these traits is known as:
Evolution
Natural selection
Genetic variation
Mutations
The process where organisms with useful traits/adaptations for their environment have a survival advatage & reproduce with more offspring to pass on these traits is known as:
Evolution
Natural selection
Genetic variation
Mutations
After the drought of 1977 on the Galapagos Islands, in 1983 there was rain for 40 days straight. What type of finches were favored during this time period?
Large beak
Medium beak
Small beak
What conclusion can be made regarding wing size between Junco samples from UCSD and Mt. Laguna?
UCSD male Juncos have longer wings that Mt. Laguna make Juncos.
Mt. Laguna Juncos have shorter wings for both males and females.
UCSD Juncos have shorter wings for both males and females.
Mt. Laguna females have short wings and males have longer wings than their UCSD counterparts.
Most human traits are controlled by two or more genes like height, hair color, eye color, and skin color. Which type of inheritance pattern does this describe?
Polygenic inheritance
Incomplete dominance
Multiple alleles
Codominance
What organism did Charles Darwin study most while on the Galapagos Islands?
Iguanas
Finches
Juncos
Seagulls
Which inheritance pattern has two alleles equally expressed in the phenotype?
Polygenic inheritance
Incomplete domianance
Multiple alleles
Codominance
What type of inheritance pattern is explained below?
Incomplete dominance
Codominance
Multiple alleles
Pure dominance
Which hormone is typically released when under stress and was studied in the Junco experiment?
Oxytocin
Estrogen
Testosterone
Cortisol
What were noticeable physical differences with the UCSD Juncos as compared to the Mt. Laguna Juncos?
More head black
Less head black
Shorter wings
More white tail feathers
Less white tail feathers
What molecules are shown below in the circle and *?
Vescicles
Neurotransmitters
Synapses
Dendrites
Which division of the nervous system controls our "fight or flight" emergency response?
Somatic nervous system
Sensory nervous system
Sympathetic nervous system
Parasympathetic nervous system
The "master" glad of the endocrine system that controls/regulates many other glands/organs of the body is the:
Pituitary gland
Pineal gland
Adrenal gland
Which structure below is are dendrites, structures that receive information for a nerve cell?
A
B
C
D
E
A 16-year-old high school student has been feeling persistently sad and unmotivated for the past several months. She struggles to concentrate in class, has lost interest in hobbies she once enjoyed, and often feels hopeless. She also has trouble sleeping and experiences changes in her appetite. Her doctor suspects that her brain may not be producing enough of a neurotransmitter responsible for mood regulation and emotional stability.
What hormone is probably the cause of this?
Dopamine
Endorphins
Norepinephrine
Serotonin
Which structure(s) represent the acon terminal; the last part of the neuron to receive/transmit a signal?
F
B
C
D
E
What type of cell is Osmosis Jones?
Red blood cell
White blood cell
Lymphatic cell
Skin cell
Which branch of the nervous system do humans voluntarily control?
Somatic nervous system
Autonomic nervous system
Sensory nervous system
Which male Junco must be the father of the offspring?
Male 3
Male 7
Male 11
Male 14
