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Endocrine System - Training Handout

Total questions: 89

Worksheet time: 45mins

Name
Class
Date
1.

What is the main function of the endocrine system?

a)

To control voluntary movements

b)

To control the internal environment (homeostasis)

c)

To digest food

d)

To transport oxygen

2.

Which chemical messenger is used by the nervous system?

a)

Hormones

b)

Neurotransmitters

c)

Enzymes

d)

Proteins

3.

Fill in the blank: The endocrine system uses _______ as chemical messengers.

a)

hormones

b)

enzymes

c)

neurotransmitters

d)

antibodies

4.

Which of the following is true about endocrine glands?

a)

They discharge secretions through a duct

b)

They release secretions directly into the bloodstream

c)

They are always constant in secretion rate

d)

They only affect digestive tissues

5.

Endocrine glands are ductless.

a)

True

b)

False

6.

What is the role of the endocrine system in the body?

a)

It is in charge of processes that happen quickly

b)

It is in charge of processes that happen slowly, such as the growth of cells

c)

It only affects the digestive system

d)

It does not influence any cells or organs

7.

In the diagram of exocrine glands, what is the function of the duct?

a)

To transport secretions to a targeted tissue

b)

To produce hormones

c)

To store neurotransmitters

d)

To absorb ions

8.

Fill in the blank: The glands and hormones of the endocrine system influence almost every _______ and _______ in the body.

a)

cell; organ

b)

bone; muscle

c)

nerve; tissue

d)

enzyme; reaction

9.

What is homeostasis? (Fill in the blank) Homeostasis is a stable internal environment involving ________, metabolism, excretion, water and salt balances.

a)

nutrition

b)

respiration

c)

photosynthesis

d)

digestion

10.

Which of the following is NOT a part of the feedback mechanism in homeostasis?

a)

Stimulus

b)

Response

c)

Digestion

d)

Signal sent to CNS

11.

Fill in the blank: In feedback mechanisms, a stimulus causes a change in the homeostatic environment and a signal is sent to the ________.

a)

CNS

b)

muscle

c)

gland

d)

bone

12.

Which diagram shows the process of returning to optimum after stress in homeostasis?

a)

Diagram A

b)

Diagram B

c)

Diagram C

d)

Diagram D

13.

Hormones are the body's chemical messenger.

a)

True

b)

False

14.

Each hormone only affects cells that are programmed to receive a specific hormone's message.

a)

True

b)

False

15.

What is the process called when most hormones use a 'turnoff' process?

a)

Positive feedback

b)

Negative feedback

c)

Open loop system

d)

Digestion

16.

Which diagram shows how hormones exert their effects on target cells?

a)

Diagram A

b)

Diagram B

c)

Diagram C

d)

Diagram D

17.

The main difference between negative feedback and positive feedback mechanisms is:

a)

Negative feedback reduces the effect of the stimulus, while positive feedback amplifies it.

b)

Negative feedback amplifies the effect of the stimulus, while positive feedback reduces it.

c)

Both mechanisms always reduce the effect of the stimulus.

d)

Both mechanisms always amplify the effect of the stimulus.

18.

Which of the following is the most common control mechanism in the body?

a)

Positive feedback

b)

Negative feedback

c)

Both equally common

d)

Neither

19.

Fill in the blank: In negative feedback, an increase in A will ________ in B.

a)

decrease

b)

increase

c)

remain the same

d)

fluctuate

20.

Which of the following is an example of negative feedback?

a)

Lactation

b)

Labor contractions

c)

Body temperature regulation

d)

Oxytocin release during birth

21.

Positive feedback mechanisms are more common than negative feedback mechanisms in the body.

a)

True

b)

False

22.

Fill in the blank: The action of oxytocin on uterine muscle during birth is an example of ________ feedback.

a)

positive

b)

negative

c)

neutral

d)

inhibitory

23.

Which gland is located in the brain and is responsible for regulating sleep-wake cycles?

a)

Pineal body

b)

Pituitary gland

c)

Thyroid gland

d)

Adrenal gland

24.

Which gland is known as the 'master gland' because it controls other endocrine glands?

a)

Pituitary

b)

Thyroid

c)

Adrenal

d)

Pineal

25.

Which gland is located in the neck and regulates metabolism?

a)

Thyroid gland

b)

Pituitary gland

c)

Adrenal gland

d)

Pancreas

26.

Which gland is responsible for producing insulin?

a)

Pancreas

b)

Thyroid

c)

Adrenal

d)

Pituitary

27.

Refer to the diagram titled 'Glands of the Endocrine System'. Which gland is located above the kidneys and produces adrenaline?

a)

Adrenal glands

b)

Pituitary gland

c)

Thyroid gland

d)

Pancreas

28.

Which gland is involved in immune system development and is located in the chest?

a)

Thymus gland

b)

Pituitary gland

c)

Thyroid gland

d)

Adrenal gland

29.

Which gland is responsible for regulating calcium levels in the blood?

a)

Parathyroids

b)

Thyroid

c)

Adrenal

d)

Pituitary

30.

Which gland is located in the lower abdomen of females and produces eggs and hormones?

a)

Ovaries

b)

Thyroid

c)

Pancreas

d)

Adrenal

31.

Which gland is located in the lower abdomen of males and produces sperm and hormones?

a)

Testicles

b)

Prostate gland

c)

Adrenal gland

d)

Pancreas

32.

What is the main function of the hypothalamus?

a)

To synchronize the information from the brain and the secretions of hormones.

b)

To control voluntary muscle movements.

c)

To produce red blood cells.

d)

To store memories.

33.

Which specialized neurons synthesize and secrete hormones in the hypothalamus?

a)

Neurosecretory cells

b)

Glial cells

c)

Motor neurons

d)

Sensory neurons

34.

The hypothalamus controls the secretions of the pituitary gland through which two types of stimulation?

a)

Nervous stimulation (posterior pituitary) and releasing hormones (anterior pituitary)

b)

Chemical stimulation (posterior pituitary) and electrical impulses (anterior pituitary)

c)

Direct blood flow regulation and enzyme activation

d)

Thermal stimulation and mechanical pressure

35.

The pituitary gland is often called the 'master gland'.

a)

True

b)

False

36.

Which part of the pituitary gland is directly controlled by nervous stimulation from the hypothalamus?

a)

Posterior pituitary

b)

Anterior pituitary

c)

Pars intermedia

d)

Infundibulum

37.

What does 'RH' stand for in the context of hypothalamic hormones?

a)

Pituitary releasing hormones

b)

Renal hormone

c)

Respiratory hormone

d)

Reproductive hormone

38.

What does 'RIH' stand for in the context of hypothalamic hormones?

a)

Pituitary release inhibiting hormones

b)

Renal inhibitory hormone

c)

Reproductive inducing hormone

d)

Respiratory inhibiting hormone

39.

Which hormone stimulates the production of milk in nursing mothers?

a)

Prolactin

b)

Insulin

c)

Adrenaline

d)

Thyroxine

40.

Which hormone is secreted by the posterior pituitary and stimulates contractions of the uterus during childbirth and allows the milk to be released from the breast tissue?

a)

Melatonin

b)

Oxytocin

c)

Thyroxine

d)

ADH

41.

What is the function of Antidiuretic hormone (ADH) secreted by the posterior pituitary?

a)

Stimulates contractions of the uterus

b)

Stimulates the kidneys to reabsorb more water

c)

Regulates metabolic rates

d)

Regulates internal clocks

42.

Fill in the blank: The pineal gland secretes ________, which regulates our internal clocks and any rhythmic activities.

a)

melatonin

b)

insulin

c)

adrenaline

d)

thyroxine

43.

Where is the pineal gland located?

a)

In the brain

b)

In the heart

c)

In the liver

d)

In the kidney

44.

The thyroid gland wraps around the trachea at the base of the neck.

a)

True

b)

False

45.

What hormone does the thyroid gland secrete?

a)

Oxytocin

b)

Melatonin

c)

Thyroxine

d)

ADH

46.

Fill in the blank: The thyroid gland needs ________ to create thyroxine, that is why salt is iodized now.

a)

iodine

b)

calcium

c)

potassium

d)

magnesium

47.

The role of thyroxine in the body is to:

a)

regulate metabolism

b)

control blood sugar levels

c)

produce antibodies

d)

aid in digestion

48.

Which hormone is secreted by the parathyroid glands and regulates the amount of calcium in the blood and its absorption by bones?

a)

Parathyroid hormone

b)

Thyroxine

c)

Insulin

d)

Adrenaline

49.

Where is the thymus gland located?

a)

Below the thyroid between the right and left lung

b)

Above the heart near the collarbone

c)

In the lower abdomen near the intestines

d)

Behind the stomach next to the pancreas

50.

What hormone does the thymus secrete that stimulates T-cell production in children?

a)

Thymosin

b)

Insulin

c)

Melatonin

d)

Cortisol

51.

Which hormone is secreted by the adrenal medulla and is responsible for the fight or flight response?

a)

Epinephrine (adrenaline) and norepinephrine

b)

Insulin

c)

Thyroxine

d)

Cortisol

52.

What hormone is secreted by the adrenal cortex to regulate reabsorption of nutrients from the kidney?

a)

Aldosterone

b)

Insulin

c)

Thyroxine

d)

Adrenaline

53.

Which hormone secreted by the adrenal gland controls the rate of metabolism of carbohydrates, fats, and proteins?

a)

Cortisol

b)

Adrenaline

c)

Insulin

d)

Thyroxine

54.

Which hormone is secreted by the pancreas to tell the liver and muscles to remove sugar from the blood and store it as fat?

a)

Insulin

b)

Glucagon

c)

Adrenaline

d)

Thyroxine

55.

What hormone does the pancreas secrete to tell the liver to break down fat stores and release sugar back into the blood?

a)

Glucagon

b)

Insulin

c)

Adrenaline

d)

Thyroxine

56.

Which hormones are secreted by the ovaries to regulate the female menstrual cycle?

a)

Estrogen and progesterone

b)

Testosterone and insulin

c)

Adrenaline and thyroxine

d)

Cortisol and melatonin

57.

What is the function of the hormone secreted by the endometrium in the uterus when a fertilized egg binds to it?

a)

To stop the menstrual cycle from progressing to menstruation

b)

To stimulate ovulation

c)

To increase blood pressure

d)

To promote bone growth

58.

What hormone do the testicles secrete that controls the development of male characteristics such as deep voice, facial hair, chest and armpit hair?

a)

Testosterone

b)

Estrogen

c)

Insulin

d)

Adrenaline

59.

What is the term for the secretion of too much hormone in the endocrine system?

a)

Hyper

b)

Hypo

c)

Iso

d)

Normo

60.

What is the term for the secretion of insufficient hormone in the endocrine system?

a)

Hypo

b)

Hyper

c)

Iso

d)

Normo

61.

Pituitary dwarfism is caused by which of the following?

a)

Hypersecretion of GH

b)

Hyposecretion of GH

c)

Hypersecretion of ADH

d)

Hyposecretion of ADH

62.

Which disorder is caused by hypersecretion of GH during childhood?

a)

Pituitary dwarfism

b)

Giantism

c)

Acromegaly

d)

Diabetes insipidus

63.

Diabetes insipidus is caused by hyposecretion of which hormone?

a)

ADH (antidiuretic hormone)

b)

Insulin

c)

Thyroxine

d)

Growth hormone

64.

Cretinism is caused by hyposecretion of thyroid hormones during which stage of life?

a)

Fetal life or infancy

b)

Adulthood

c)

Old age

d)

Puberty

65.

Which disorder is an autoimmune disease and the most common form of hyperthyroidism?

a)

Grave's Disease

b)

Hashimoto's Thyroiditis

c)

Addison's Disease

d)

Cushing's Syndrome

66.

Goiter is the enlargement of which gland?

a)

Thyroid gland

b)

Pituitary gland

c)

Adrenal gland

d)

Pineal gland

67.

Hypoparathyroidism results in which condition?

a)

Muscle tetany

b)

Hyperglycemia

c)

Goiter

d)

Cushing's syndrome

68.

Hyperparathyroidism produces which bone disorder?

a)

Osteitis fibrosa cystica

b)

Osteomalacia

c)

Paget's disease

d)

Osteopetrosis

69.

Cushing's Syndrome is caused by hypersecretion of which hormone?

a)

Cortisol

b)

Insulin

c)

Thyroxine

d)

Adrenaline

70.

Addison's Disease is caused by hyposecretion of which hormones?

a)

Glucocorticoids and aldosterone

b)

Insulin and glucagon

c)

Thyroxine and calcitonin

d)

Adrenaline and noradrenaline

71.

Type I or insulin-dependent diabetes mellitus is caused by which of the following?

a)

Down-regulation of insulin receptors

b)

Absolute deficiency of insulin

c)

Excess insulin

d)

Excess cortisol

72.

Type II or insulin-independent diabetes is caused by which of the following?

a)

Absolute deficiency of insulin

b)

Down-regulation of insulin receptors

c)

Excess insulin

d)

Excess cortisol

73.

Hyperinsulinism results in which condition?

a)

Hypoglycemia (low blood sugar) and possibly insulin shock

b)

Hyperglycemia (high blood sugar) and diabetic coma

c)

Hypertension (high blood pressure)

d)

Hyperthyroidism (overactive thyroid)

74.

Which type of hormones are non-steroid, water soluble, and cannot fit through the membrane of the target cell?

a)

Peptides and Amines

b)

Steroid hormones

c)

Fat-soluble hormones

d)

All of the above

75.

Protein hormones (first messengers) bind to receptors on the target cell, triggering the activation of which type of messenger to affect the cell's activity?

a)

First messenger

b)

Second messenger

c)

Third messenger

d)

None of the above

76.

Fill in the blank: The most common chemical signals (second messengers) generated by hormone-receptor complexes are ______ and IP3.

a)

cAMP

b)

ATP

c)

GTP

d)

NADH

77.

Steroid hormones bind to receptors on the plasma membrane of the target cell.

a)

True

b)

False

78.

Steroid hormones are fat-soluble and influence cell activity by binding to receptors within the target cell. What is the next step after the hormone binds to the receptor?

a)

Activation of G protein

b)

Complex binds to steroid response element on DNA

c)

Release of calcium ions

d)

Activation of adenylyl cyclase

79.

Fill in the blank: Hormone-receptor complex acts as a transcription factor to turn target genes '____' or '____'.

a)

on, off

b)

up, down

c)

open, close

d)

start, stop

80.

Which of the following hormone classes consists of short chains of amino acids and is found in organs such as the pituitary, parathyroid, heart, stomach, liver, and kidneys?

a)

Peptides

b)

Amines

c)

Steroids

d)

Eicosanoids

81.

Which hormone class is derived from tyrosine and secreted by the thyroid and adrenal cortex?

a)

Peptides

b)

Amines

c)

Steroids

d)

Eicosanoids

82.

Fill in the blank: Steroid hormones are lipids derived from ________ and are secreted by the gonads, adrenal cortex, and placenta.

a)

cholesterol

b)

glucose

c)

amino acids

d)

fatty acids

83.

Which hormone class is produced from 20-carbon fatty acid, arachadonic acid, and is produced in all cells except RBCs?

a)

Peptides

b)

Amines

c)

Steroids

d)

Eicosanoids

84.

Which of the following is NOT a property of Peptide/Protein hormones?

a)

A) Hydrophilic

b)

B) Large

c)

C) Can fit through membrane

d)

D) Second messenger mechanism of action

85.

Fill in the blank: The most common hormone type is ________.

a)

Peptide/Protein

b)

Steroid

c)

Amino acid derivative

d)

Lipid

86.

Which hormone class is synthesized from a single amino acid and includes melatonin from tryptophan and catecholamines from tyrosine?

a)

Peptide/Protein

b)

Amine

c)

Steroid

d)

Eicosanoid

87.

Which hormone class travels in blood with a carrier and binds to cytoplasmic or nuclear receptors?

a)

Peptide/Protein

b)

Amine

c)

Steroid

d)

Eicosanoid

88.

Fill in the blank: An example of a steroid hormone is ________.

a)

estradiol

b)

insulin

c)

thyroxine

d)

glucagon

89.

Eicosanoids mediate inflammation and act as second messengers.

a)

True

b)

False