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Biology Mid-Year Review

Total questions: 150

Worksheet time: 1hrs 15mins

Name
Class
Date
1.

Which of the following best explains why pseudoscience does not meet the criteria of science?

a)

It relies too heavily on quantitative data

b)

It cannot be tested or potentially falsified

c)

It changes too often based on new evidence

d)

It requires peer review but not replication

2.

A student claims that a scientific idea must remain unchanged to be considered reliable. Which CONPTT principle contradicts this statement?

a)

Consistent

b)

Observable

c)

Predictable

d)

Tentative

3.

A biologist measures how plant growth changes when soil pH is altered. Which variable is the independent variable?

a)

Height of the plant

b)

Type of plant used

c)

Soil pH

d)

Amount of water added

4.

Which scenario best represents a scientific investigation, not a controlled experiment?

a)

Measuring reaction speed at different temperatures

b)

Observing dolphin communication patterns for 6 months

c)

Testing how fertilizer amount affects bean germination

d)

Measuring mass loss during a chemical reaction

5.

Which of the following statements about hypotheses is accurate?

a)

A hypothesis is proven correct if data supports it

b)

A hypothesis is an educated guess with no basis in prior knowledge

c)

A hypothesis can be supported or not supported by data

d)

A hypothesis must be rewritten every time results differ

6.

Which of the following is the best example of a properly structured scientific question?

a)

Why do plants grow?

b)

How does light affect plant growth?

c)

Will plants grow differently?

d)

What will happen if plants receive sunlight?

7.

A researcher conducts 25 trials of an experiment before drawing conclusions. Which statement best explains why this improves validity?

a)

More trials increase the natural phenomena involved

b)

Repetition increases the consistency and reliability of the results

c)

More trials allow changing multiple variables at once

d)

Repetition reduces the need for a control group

8.

Why is replication by other scientists essential in experimental design?

a)

It allows other scientists to rewrite the original hypothesis

b)

It ensures the results are consistent when the procedure is repeated

c)

It gives scientists a chance to improve the data table format

d)

It eliminates the need for controlled variables

9.

A student writes the following statement: "If the amount of caffeine a person consumes increases, then their heart rate will increase because caffeine is a stimulant." Which part of a hypothesis does this sentence represent?

a)

It is invalid because it includes a reason ("because…")

b)

It identifies both IV and DV and gives a predicted relationship

c)

It should not include prior knowledge

d)

It is inaccurate because it uses an "if/then" format

10.

In a well-designed controlled experiment, the control group is essential because it:

a)

Receives the independent variable first

b)

Increases the number of dependent variables

c)

Serves as a baseline to compare experimental results

d)

Eliminates the need for repetition

11.

What causes the polarity of a water molecule?

a)

Equal sharing of electrons between hydrogen and oxygen

b)

Unequal sharing of electrons, giving oxygen a partial negative charge

c)

Attraction between two water molecules

d)

The high specific heat of water

12.

Hydrogen bonds form between water molecules because:

a)

The covalent bonds within each molecule are weak

b)

Opposite partial charges on different molecules attract each other

c)

Electrons are transferred between water molecules

d)

Water molecules are nonpolar

13.

Why is water considered the “universal solvent”?

a)

It dissolves only nonpolar molecules

b)

It reacts chemically with most solutes

c)

Its polarity allows it to easily dissolve many polar and ionic substances

d)

It has no partial charges

14.

Which property of water explains why certain insects can walk on the surface of water?

a)

Adhesion

b)

Universal solvent

c)

High specific heat

d)

Cohesion

15.

Capillary action in plants results from which combination of water properties?

a)

Cohesion and high specific heat

b)

Adhesion and cohesion

c)

Polarity and freezing

d)

Solubility and surface tension

16.

Why does water require a large amount of energy to increase in temperature?

a)

Water molecules repel each other strongly

b)

Ice is denser than liquid water

c)

Hydrogen bonds must be broken before molecules can move faster

d)

Water contains no intermolecular forces

17.

When salt dissolves in water, the salt is considered the:

a)

Solvent

b)

Solute

c)

Solution

d)

Hydrogen bond

18.

Which statement correctly explains why ice floats on liquid water?

a)

Ice is more dense than liquid water

b)

Water molecules contract when they freeze

c)

The structure of water expands upon freezing, decreasing density

d)

Freezing removes all hydrogen bonds

19.

A drop of water clings to the side of a glass slide. This observation best demonstrates:

a)

Cohesion

b)

Adhesion

c)

Surface tension

d)

High specific heat

20.

A lake stays insulated in winter because:

a)

Ice sinks, cooling the water below

b)

Ice floats, forming a layer that traps heat in the water beneath

c)

Frozen water loses all polarity

d)

Water cannot freeze above 0°C

21.

Which of the following correctly matches a macromolecule with its monomer?

a)

Carbohydrates – amino acids

b)

Lipids – nucleotides

c)

Proteins – fatty acids

d)

Nucleic acids – nucleotides

22.

Which statement best explains why carbohydrates are ideal for quick energy?

a)

They contain nitrogen, which speeds up chemical reactions

b)

Their monosaccharides can be rapidly broken down for cellular respiration

23.

Which pair correctly identifies a disaccharide and its biological role?

a)

Glucose – main energy molecule produced by plants

b)

Sucrose – transports sugar in plants through the phloem

c)

Cellulose – long-term energy storage in animals

d)

Glycogen – structural support in plant cell walls

24.

What structural feature distinguishes proteins from carbohydrates and lipids?

a)

Presence of hydrogen

b)

R-group (side chain) on the monomer

c)

Long chains of monosaccharides

d)

Ability to form colloidal suspensions

25.

Polysaccharides differ from monosaccharides in that they:

a)

Are sweet to the taste and dissolve easily in water

b)

Must be digested before absorption and do not form true solutions

c)

Are made only of lipids

d)

Contain nitrogen and phosphorus

26.

A lipid contains the elements CHO, but with far less oxygen than carbohydrates. Which lipid is used primarily for long-term energy storage?

a)

Phospholipid

b)

Triglyceride

c)

Steroid

d)

Cellulose

27.

Which statement best describes the structure of a phospholipid in relation to its function?

a)

Its hydrophobic nature makes it dissolve easily in water

b)

Its insolubility in water helps form the cell membrane

c)

Its amino acids form hydrogen bonds in the membrane

d)

Its nucleotides store genetic information

28.

Which macromolecule contains the instructions for building all proteins in living organisms?

a)

Lipids

b)

Polysaccharides

c)

Nucleic acids

d)

Triglycerides

29.

ATP is classified as a nucleic acid because:

a)

It stores long-term energy in fat molecules

b)

It is composed of amino acids linked together

c)

It contains a nucleotide structure with a phosphate group

d)

It forms part of the cell membrane

30.

Which of the following macromolecules is MOST directly involved in growth, repair, and enzyme function?

a)

Lipids

b)

Proteins

c)

Carbohydrates

d)

Nucleic acids

31.

Which evidence provides the earliest support for life on Earth?

a)

Miller-Urey experiment results

b)

Stromatolite fossils in Western Australia dating to ~3.5 billion years ago

c)

Formation of proteinoids by Sidney Fox

d)

Pasteur’s sterile broth experiment

32.

According to Oparin, what characteristic of the early Earth’s atmosphere allowed life to originate?

a)

Oxygen-rich atmosphere

b)

Reducing (oxygen-poor) atmosphere

c)

High levels of nitrogen only

d)

Presence of complex DNA molecules

33.

The Miller-Urey experiment demonstrated that:

a)

Organic molecules such as amino acids can form from simple gases under conditions simulating early Earth

b)

Life spontaneously arises from nutrient-rich broth in sealed flasks

c)

Complex DNA molecules assembled in the early atmosphere without precursors

d)

Early Earth’s atmosphere contained abundant free oxygen supporting modern life

34.

Sidney Fox showed that amino acids could:

a)

Form DNA spontaneously

b)

Link together when heated without water to form protein-like structures called proteinoids

c)

Survive in the presence of oxygen-rich atmospheres

d)

Be synthesized only inside living cells

35.

Louis Pasteur’s experiments led to which scientific principle?

a)

Spontaneous generation

b)

Biogenesis – life arises only from pre-existing life

c)

Reducing atmosphere hypothesis

d)

Endosymbiotic theory

36.

The Endosymbiotic Theory primarily explains:

a)

How stromatolites formed 3.5 billion years ago

b)

How mitochondria and chloroplasts originated from symbiotic prokaryotic cells

c)

How proteins form from amino acids

d)

How the Miller-Urey experiment simulates early Earth

37.

Which of the following statements about mitochondria and chloroplasts is true according to the Endosymbiotic Theory?

a)

Both organelles are found in all prokaryotic cells

b)

Chloroplasts originated from engulfed cyanobacteria, and mitochondria from another prokaryotic cell

c)

Both organelles arose spontaneously from nonliving molecules

d)

Mitochondria are only found in plant cells

38.

Why was Oparin skeptical that life could originate under current Earth conditions?

a)

Modern Earth has too few amino acids

b)

The current atmosphere is oxidizing rather than reducing

c)

Water cannot exist as a liquid today

d)

Lightning no longer provides energy

39.

Which combination of scientists and contributions is correct?

a)

Miller-Urey – disproved spontaneous generation

b)

Pasteur – synthesized amino acids under reducing conditions

c)

Fox – formed proteinoids from amino acids

d)

Margulis – first created Miller-Urey apparatus

40.

The “primordial soup” hypothesis refers to:

a)

The formation of oceans on early Earth

b)

Accumulation of organic molecules in early Earth’s oceans, leading to life

c)

Pasteur’s sterile broth experiment

d)

Symbiotic bacteria forming mitochondria

41.

Which scientist is credited with proposing that all plants are made of cells?

a)

Theodor Schwann

b)

Matthias Schleiden

c)

Rudolph Virchow

d)

Louis Pasteur

42.

The third part of the cell theory, “all cells come from pre-existing cells,” was proposed by:

a)

Schleiden

b)

Schwann

c)

Virchow

d)

Margulis

43.

Which of the following statements is NOT part of the cell theory?

a)

All organisms are made of one or more cells

b)

Cells are the basic unit of life

c)

Cells can spontaneously appear from nonliving matter

d)

All cells come from pre-existing cells

44.

Which type of organism consists of only a single cell?

a)

Multicellular organism

b)

Unicellular organism

c)

Prokaryotic only

d)

Eukaryotic only

45.

A compound microscope has high magnification but low resolution. Which of the following is a correct use for it?

a)

Viewing large, three-dimensional specimens during dissection

b)

Observing living individual cells

c)

Examining the exterior of a gold-coated specimen

d)

Passing electrons through thin slices of a specimen

46.

Which microscope produces a 3-D image of the exterior of a specimen and requires coating the specimen in gold?

a)

Compound microscope

b)

Dissection microscope

c)

Scanning electron microscope

d)

Transmission electron microscope

47.

Which microscope allows electrons to pass through thin slices of a specimen to create a 2-D image with high magnification and high resolution?

a)

Compound microscope

b)

Dissection microscope

c)

Scanning electron microscope

d)

Transmission electron microscope

48.

Which statement about dissection microscopes is accurate?

a)

They have high magnification and can see individual cells

b)

They produce 2-D images only

c)

They are used to view larger specimens in 3-D

d)

They require coating the specimen with metal

49.

The collaboration between Schleiden and Schwann led to the development of:

a)

The endosymbiotic theory

b)

The first two parts of the cell theory

c)

The discovery of DNA

d)

The idea of spontaneous generation

50.

Scientific theories differ from hypotheses in that theories:

a)

Are single, untested predictions

b)

Seek to explain phenomena and are supported by multiple lines of evidence

c)

Cannot be modified based on new data

d)

Are only accepted if experiments are performed by one scientist

51.

Which of the following structures is found in both prokaryotic and eukaryotic cells?

a)

Nucleus

b)

Ribosome

c)

Mitochondria

d)

Chloroplast

52.

Which statement correctly describes prokaryotic cells?

a)

They have a nucleus and membrane-bound organelles

b)

They are always multicellular

c)

They have DNA in the form of a circular plasmid and no nucleus

d)

They contain chloroplasts for photosynthesis

53.

Flagella in prokaryotic cells are used for:

a)

Photosynthesis

b)

Cellular respiration

c)

Movement

d)

Protein synthesis

54.

Which organelle is responsible for packaging and moving proteins to the outside of the eukaryotic cell?

a)

Ribosome

b)

Golgi apparatus

c)

Rough ER

d)

Mitochondria

55.

What is the primary function of the chloroplast in plant cells?

a)

Cellular respiration

b)

Protein synthesis

c)

Photosynthesis

d)

Storage of water

56.

The rough endoplasmic reticulum is specialized for:

a)

Making and transporting proteins

b)

Making and transporting lipids

c)

Producing ATP

d)

Digesting cellular waste

57.

In plant cells, which structure works with the cell wall to maintain shape and store water?

a)

Chloroplast

b)

Large central vacuole

c)

Mitochondria

d)

Lysosome

58.

How do cilia differ from flagella in eukaryotic cells?

a)

Cilia are longer than flagella

b)

Cilia are short hair-like projections; flagella are long whip-like structures

c)

Cilia are found only in prokaryotes

d)

Cilia produce ATP for the cell

59.

Which organelle is the site of ATP production in eukaryotic cells?

a)

Ribosome

b)

Mitochondria

c)

Golgi apparatus

d)

Smooth ER

60.

Which statement correctly describes the pathway of protein production in eukaryotic cells?

a)

Proteins are produced in the nucleus, move through the Golgi, and are packaged by the ribosome

b)

Proteins are produced in the ribosome, move through the ER, and are packaged by the Golgi apparatus

c)

Proteins are produced in the mitochondria and stored in the vacuole

d)

Proteins are synthesized in the chloroplast and transported by lysosomes

61.

Which part of a phospholipid is hydrophilic?

a)

Fatty acid tails

b)

Phosphate head

c)

Glycerol backbone

d)

Cholesterol molecule

62.

The cell membrane is described as a “fluid mosaic model” because:

a)

It is rigid and solid

b)

Phospholipids and proteins move laterally, creating flexibility

c)

It contains only proteins and cholesterol

d)

Molecules cannot pass through it

63.

Which statement about the cell membrane is correct?

a)

It is impermeable to all substances

b)

It is selectively permeable, allowing some substances in and out while restricting others

c)

It consists solely of phospholipids

d)

It is static and cannot move

64.

Which process does NOT require cellular energy (ATP)?

a)

Osmosis

b)

Endocytosis

c)

Protein pumps

d)

Exocytosis

65.

In which type of solution does a cell swell as water enters?

a)

Isotonic

b)

Hypertonic

c)

Hypotonic

d)

Facilitated

66.

Facilitated diffusion differs from simple diffusion because:

a)

It moves molecules from low to high concentration

b)

It requires protein channels to transport large or polar molecules

c)

It always uses ATP

d)

It moves water only

67.

Which of the following correctly pairs a transport process with its mechanism?

a)

Phagocytosis – cell uses a vesicle to release molecules

b)

Exocytosis – cell engulfs large particles

c)

Protein pump – molecules are actively transported using energy

d)

Osmosis – requires ATP to move solutes

68.

Hypertonic solutions cause water to:

a)

Enter the cell, swelling it

b)

Leave the cell, causing it to shrivel

c)

Remain balanced inside and outside the cell

d)

Move only through protein channels

69.

Which components help maintain membrane fluidity?

a)

Saturated fatty acid tails

b)

Unsaturated fatty acid tails

c)

Carbohydrate chains only

d)

Cytoplasm

70.

Which correctly describes endocytosis?

a)

Large molecules are engulfed into the cell using vesicles

b)

Molecules exit the cell via vesicles

c)

Small molecules diffuse freely across the membrane

d)

Water moves from low to high concentration

71.

Which of the following are the reactants of photosynthesis?

a)

Glucose and oxygen

b)

Water, carbon dioxide, and sunlight

c)

ATP and oxygen

d)

Carbon dioxide and glucose

72.

Where does photosynthesis occur in plant cells?

a)

Mitochondria

b)

Cytoplasm

c)

Chloroplast

d)

Nucleus

73.

What is the primary role of chlorophyll in photosynthesis?

a)

Break down glucose into ATP

b)

Collect sunlight energy to drive chemical reactions

c)

Transport water from roots to leaves

d)

Release carbon dioxide

74.

Which structure in the leaf allows carbon dioxide to enter and oxygen to exit?

a)

Xylem

b)

Stomata

c)

Phloem

d)

Chloroplast

75.

Aerobic respiration produces approximately how many ATP molecules from 1 glucose molecule?

a)

2

b)

12

c)

36

d)

100

76.

Where does aerobic cellular respiration occur?

a)

Chloroplast

b)

Cytoplasm

c)

Mitochondria

d)

Nucleus

77.

Anaerobic respiration differs from aerobic respiration in that it:

a)

Requires oxygen

b)

Produces more ATP per glucose molecule

c)

Occurs in the cytoplasm and produces less ATP

d)

Only occurs in plant cells

78.

Lactic acid fermentation is an example of:

a)

Aerobic respiration

b)

Anaerobic respiration

c)

Photosynthesis

d)

Alcoholic fermentation

79.

Alcoholic fermentation produces which byproducts?

a)

Lactic acid and ATP

b)

Ethanol and ATP

c)

Oxygen and glucose

d)

Carbon dioxide only

80.

How are photosynthesis and aerobic respiration interrelated?

a)

Photosynthesis creates glucose and oxygen, which are used in respiration; respiration produces CO2 and H2O, which are used in photosynthesis

b)

Photosynthesis only occurs at night; respiration only occurs during the day

c)

Both produce lactic acid as a byproduct

d)

Respiration occurs in plants; photosynthesis occurs in animals

81.

Enzymes speed up chemical reactions by:

a)

Increasing the activation energy

b)

Providing an alternative pathway with lower activation energy

c)

Changing the substrate permanently

d)

Acting as a source of energy

82.

Which term describes the specific region of an enzyme where the substrate binds?

a)

Cofactor

b)

Active site

c)

Denaturation site

d)

Ribosome

83.

What happens to an enzyme when it is denatured?

a)

It works faster

b)

Its shape changes and it can no longer bind the substrate

c)

It becomes more specific for its substrate

d)

It turns into ATP

84.

Which of the following can denature an enzyme?

a)

Optimal temperature

b)

Optimal pH

c)

Excessively high temperature or extreme pH

d)

Moderate substrate concentration

85.

How does substrate concentration affect enzyme activity?

a)

Increasing substrate always slows the reaction

b)

Reaction rate increases until enzymes are saturated, then plateaus

c)

Substrate concentration has no effect

d)

Reaction stops if substrate concentration is low

86.

Which protein structure level describes the folding of a coiled polypeptide into a three-dimensional shape?

a)

Primary

b)

Secondary

c)

Tertiary

d)

Quaternary

87.

Hemoglobin, actin, and myosin are examples of proteins that function in:

a)

Digestion, oxygen transport, and movement

b)

Photosynthesis, cellular respiration, and fermentation

c)

ATP production, lipid transport, and DNA replication

d)

Cell wall formation, vacuole storage, and endocytosis

88.

Which statement best explains enzyme specificity?

a)

Enzymes can catalyze any reaction in the cell

b)

Each enzyme has a 3-D shape that only fits a specific substrate

c)

Enzymes work best at extremely high temperatures

d)

Enzyme activity is random and unpredictable

89.

What is the main function of antibodies in living organisms?

a)

Transport oxygen

b)

Facilitate muscular contraction

c)

Defend the body against foreign invaders like bacteria and viruses

d)

Digest food

90.

The primary structure of a protein is:

a)

Two or more polypeptide chains linked together

b)

The three-dimensional folding of a polypeptide chain

c)

A single, linear sequence of amino acids

d)

Coiled or pleated sections of the polypeptide chain

91.

DNA is described as a “twisted ladder” because it is shaped like:

a)

A single strand

b)

A double helix

c)

A triple helix

d)

A circular plasmid

92.

Which of the following correctly pairs DNA bases according to the Base Pairing Rule?

a)

Adenine – Guanine, Cytosine – Thymine

b)

Adenine – Thymine, Guanine – Cytosine

c)

Adenine – Cytosine, Guanine – Thymine

d)

Adenine – Uracil, Guanine – Cytosine

93.

What type of bond connects the nitrogenous bases in a DNA molecule?

a)

Covalent bonds

b)

Ionic bonds

c)

Hydrogen bonds

d)

Peptide bonds

94.

During which phase of the cell cycle does DNA replication occur?

a)

Mitosis

b)

Cytokinesis

c)

Interphase

d)

Anaphase

95.

Which enzyme unwinds the DNA double helix by breaking hydrogen bonds?

a)

DNA Polymerase

b)

Ligase

c)

Helicase

d)

Primase

96.

What is the main function of DNA Polymerase?

a)

Unwinds the DNA molecule

b)

Assembles new nucleotides into a DNA strand and proofreads the sequence

c)

Creates a primer for replication

d)

Seals gaps between DNA fragments

97.

Ligase is responsible for:

a)

Starting DNA replication

b)

Proofreading the DNA

c)

Binding free-floating nucleotides to the DNA strand

d)

Creating a primer for DNA Polymerase

98.

Primase plays an essential role in DNA replication by:

a)

Unwinding the DNA double helix

b)

Synthesizing an RNA primer to initiate replication

c)

Proofreading DNA sequences

d)

Joining Okazaki fragments

99.

DNA stores genetic information in:

a)

Proteins

b)

Amino acids

c)

Nitrogenous base sequences

d)

Ribosomes

100.

Which of the following statements is TRUE about DNA replication?

a)

DNA replication produces two identical DNA molecules

b)

DNA replication occurs after mitosis

c)

Helicase joins nucleotides together

d)

Only one enzyme is needed for DNA replication

101.

Which of the following correctly describes RNA?

a)

Double-stranded, contains thymine, deoxyribose sugar

b)

Single-stranded, contains uracil, ribose sugar

c)

Double-stranded, contains uracil, ribose sugar

d)

Single-stranded, contains thymine, deoxyribose sugar

102.

The central dogma of molecular biology is:

a)

DNA → Protein → RNA

b)

Protein → DNA → RNA

c)

DNA → RNA → Protein

d)

RNA → DNA → Protein

103.

Which type of RNA carries the genetic code from the DNA to the ribosome?

a)

rRNA

b)

tRNA

c)

mRNA

d)

tRNA and rRNA

104.

What is the role of tRNA during translation?

a)

Carries DNA from the nucleus to the ribosome

b)

Catalyzes the formation of peptide bonds

c)

Reads the mRNA codon and brings the corresponding amino acid

d)

Synthesizes mRNA from DNA

105.

Which enzyme initiates transcription by copying DNA into RNA?

a)

DNA Polymerase

b)

Ligase

c)

RNA Polymerase

d)

Helicase

106.

Translation occurs in which part of the cell?

a)

Nucleus

b)

Ribosome

c)

Mitochondria

d)

Chloroplast

107.

Which of the following is the correct start codon for translation?

a)

AUG

b)

UAA

c)

CAA

d)

CGA

108.

Stop codons signal the ribosome to:

a)

Start translation

b)

Add more amino acids

c)

End translation and release the polypeptide

d)

Transcribe DNA into RNA

109.

Peptide bonds form between:

a)

Nucleotides

b)

Amino acids

110.

Which statement best summarizes the relationship between transcription and translation?

a)

Transcription converts RNA into DNA; translation converts DNA into protein

b)

Transcription copies DNA into mRNA; translation decodes mRNA to build a polypeptide

c)

Transcription occurs in the cytoplasm; translation occurs in the nucleus

d)

Both processes produce RNA from protein

111.

Cells spend most of their time in which phase of the cell cycle?

a)

Mitosis

b)

Interphase

c)

Cytokinesis

d)

G2 phase

112.

During which phase of interphase does DNA replication occur?

a)

G1

b)

S phase

c)

G2

d)

Mitosis

113.

In which stage of mitosis do chromosomes line up along the middle of the cell?

a)

Prophase

b)

Metaphase

c)

Anaphase

d)

Telophase

114.

What is the result of mitosis in somatic cells?

a)

Two genetically identical diploid daughter cells

b)

Four genetically identical haploid daughter cells

c)

Two genetically unique haploid cells

d)

One cell with double the chromosomes

115.

Cyclins are proteins that:

a)

Control the rate of the cell cycle

b)

Cause mutations in DNA

c)

Form the spindle fibers

d)

Replicate DNA

116.

Which type of gene mutation results from the insertion or deletion of a nucleotide?

a)

Point mutation

b)

Frameshift mutation

c)

Silent mutation

d)

Missense mutation

117.

What is the main difference between a point mutation and a frameshift mutation?

a)

Point mutation affects multiple codons; frameshift affects one codon

b)

Point mutation substitutes one nucleotide; frameshift shifts all subsequent codons

c)

Frameshift mutations never change proteins; point mutations always do

d)

Point mutations only occur in RNA

118.

Binary fission occurs in:

a)

Eukaryotic somatic cells

b)

Prokaryotic cells like bacteria and archaea

c)

Plant cells only

d)

Animal cells only

119.

Which step is common to both mitosis and binary fission?

a)

PMAT

b)

DNA replication, cell growth, cytokinesis, formation of daughter cells

c)

Crossing over

d)

Meiosis

120.

Cancer can result from:

a)

Uncontrolled cell cycle due to mutations in proto-oncogenes or tumor suppressor genes

b)

Increased apoptosis and reduced cell division

c)

Accurate DNA repair and regulated checkpoints

d)

Balanced cyclin–CDK activity

121.

How many haploid daughter cells are produced at the end of meiosis?

a)

2

b)

4

c)

1

d)

8

122.

During which phase of meiosis does crossing over occur?

a)

Prophase 1

b)

Metaphase 1

c)

Prophase 2

d)

Anaphase 2

123.

What is the main difference between meiosis 1 and meiosis 2?

a)

Meiosis 1 separates sister chromatids; meiosis 2 separates homologous chromosomes

b)

Meiosis 1 separates homologous chromosomes; meiosis 2 separates sister chromatids

c)

Meiosis 1 produces diploid cells; meiosis 2 produces diploid cells

d)

Meiosis 1 does not involve spindle fibers; meiosis 2 does

124.

In which cells does meiosis occur in humans?

a)

Somatic cells

b)

Gametes (sex cells)

c)

Liver cells

d)

Muscle cells

125.

Which of the following statements is TRUE about the cells produced by meiosis?

a)

They are genetically identical

b)

They are haploid and genetically different

c)

They are diploid and genetically identical

d)

They are tetraploid

126.

A chromosomal mutation that occurs when a segment of a chromosome flips and reattaches is called:

a)

Deletion

b)

Inversion

c)

Translocation

d)

Nondisjunction

127.

Nondisjunction results in:

a)

Extra or missing chromosomes in gametes

b)

A flipped segment of a chromosome

c)

A gene sequence repeated in a chromosome

d)

Translocation between homologous chromosomes

128.

Translocation occurs when:

a)

A segment of a chromosome is lost

b)

A segment of a chromosome attaches to a non-homologous chromosome

c)

A segment of a chromosome flips backwards

d)

A gene is duplicated within the same chromosome

129.

Which phase of meiosis is responsible for aligning homologous chromosome pairs at the metaphase plate?

a)

Prophase 1

b)

Metaphase 1

c)

Metaphase 2

d)

Anaphase 2

130.

The primary purpose of meiosis is to:

a)

Produce identical somatic cells

b)

Repair damaged cells

c)

Produce genetically diverse haploid gametes for sexual reproduction

d)

Copy DNA for mitosis

131.

Which of the following best describes a scientific hypothesis?

a)

A guess with no prior research

b)

A predicted outcome based on observations, research, and prior knowledge

c)

A statement that is always proven correct after an experiment

d)

A scientific law

132.

What property of water allows it to move up plant roots through capillary action?

a)

High specific heat

b)

Cohesion and adhesion

c)

Universal solvent capability

d)

Polarity of oxygen only

133.

Which macromolecule’s monomer is an amino acid?

a)

Carbohydrates

b)

Lipids

c)

Proteins

d)

Nucleic acids

134.

Which scientist disproved spontaneous generation by showing that microorganisms come from pre-existing life?

a)

Oparin

b)

Pasteur

c)

Miller-Urey

d)

Margulis

135.

Which organelle is responsible for producing ATP through cellular respiration?

a)

Chloroplast

b)

Ribosome

c)

Mitochondria

d)

Golgi apparatus

136.

In which type of solution will a cell swell and possibly burst due to water intake?

a)

Isotonic

b)

Hypertonic

c)

Hypotonic

d)

Saturated

137.

During which phase of mitosis do sister chromatids separate and move to opposite poles?

a)

Prophase

b)

Metaphase

c)

Anaphase

d)

Telophase

138.

Which enzyme unwinds the DNA helix during DNA replication?

a)

DNA Polymerase

b)

Ligase

c)

Primase

d)

Helicase

139.

Which process converts glucose into ATP in the absence of oxygen?

a)

Aerobic respiration

b)

Anaerobic respiration

c)

Photosynthesis

d)

Transcription

140.

Which type of RNA carries amino acids to the ribosome and matches them to the codons on mRNA?

a)

mRNA

b)

rRNA

c)

tRNA

d)

DNA

141.

Which part of the cell membrane is primarily responsible for forming a barrier between the inside and outside of the cell?

a)

Cholesterol

b)

Phospholipids

c)

Proteins

d)

Carbohydrates

142.

Which statement best describes enzymes?

a)

They are consumed in chemical reactions

b)

They lower the activation energy of a reaction

c)

They change the products of a reaction

d)

They work on any substrate

143.

During which phase of interphase does the cell grow and synthesize new proteins and organelles?

a)

G1

b)

S

c)

G2

d)

M

144.

Which statement about prokaryotes is true?

a)

They contain a nucleus

b)

They have membrane-bound organelles

c)

They reproduce through binary fission

d)

They have mitochondria for ATP production

145.

Which statement about DNA is correct?

a)

RNA contains thymine, DNA contains uracil

b)

Adenine pairs with guanine

c)

DNA is double-stranded with a sugar-phosphate backbone

d)

DNA is single-stranded with ribose sugar

146.

What is the main role of chloroplasts in plant cells?

a)

Cellular respiration

b)

Protein synthesis

c)

Photosynthesis

d)

Lipid storage

147.

Which of the following is an example of passive transport?

a)

Endocytosis

b)

Exocytosis

c)

Facilitated diffusion

d)

Protein pump

148.

Which macromolecule stores and transmits genetic information?

a)

Protein

b)

Lipid

c)

Nucleic acid

d)

Carbohydrate

149.

What is the primary product of photosynthesis that stores energy for the plant?

a)

ATP

b)

Glucose

c)

Oxygen

d)

Carbon dioxide

150.

Which type of mutation is caused by the substitution of a single nucleotide?

a)

Frameshift mutation

b)

Point mutation

c)

Deletion

d)

Nondisjunction