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Oral Pathology Hesi Remediation #2

Total questions: 149

Worksheet time: 1hrs 15mins

Name
Class
Date
1.

Which condition is not diagnosed through clinical appearance?

a)

Compound odontoma

b)

Black hairy tongue

c)

Fordyce granules

d)

Mandibular tori

2.

Which condition is diagnosed through clinical appearance?

a)

Periapical cemento-osseous dysplasia

b)

Unerupted mesiodens

c)

Traumatic bone cyst

d)

Fordyce granules

3.

Retrocuspid papillae are located on the

a)

floor of the mouth

b)

gingival margin of the lingual aspect of mandibular cuspids

c)

palate

d)

canine eminence

4.

A lesion with a stemlike base is described as

a)

macular

b)

pedunculated

c)

sessile

5.

Which papillae are elongated in the condition known as black hairy tongue?

a)

Fungiform papillae elongation

b)

Filiform papillae elongation

c)

Foliate papillae elongation

d)

Circumvallate papillae elongation

6.

When exudate formation is excessive, a drainage tract through injured tissue is often termed what?

a)

leukocytosis response

b)

emigration process

c)

a fistula formation

d)

erythema reaction

7.

Neutrophils constitute what approximate percentage of the entire white blood cell population?

a)

90 percent total

b)

5 percent total

c)

20 percent total

d)

65 percent total

8.

Excessive scarring in skin is termed what?

a)

a hematoma mass

b)

tertiary intention healing

c)

primary intention healing

d)

a keloid lesion

9.

Aspirin burn on the oral mucosa is most commonly caused by what action?

a)

Ingesting too many tablets

b)

Surrounding mucosa becomes necrotic

c)

Placing aspirin on the tooth

d)

The burn is painless overall

10.

Which statement best describes leukocytosis in clinical contexts?

a)

Migration out of vessels

b)

Formation of a tissue tract

c)

Localized redness only

d)

Elevated white cell count

11.

Which term best matches the outward movement of leukocytes from blood vessels into tissues during inflammation?

a)

Keloid formation

b)

Fistula creation

c)

Erythema change

d)

Diapedesis process

12.

Which tongue papillae primarily function in mechanical processing rather than taste perception?

a)

Filiform papillae

b)

Fungiform papillae

c)

Foliate papillae

d)

Circumvallate papillae

13.

What clinical feature most directly indicates tissue necrosis following topical aspirin application?

a)

Rapid leukocytosis surge

b)

Immediate fistula formation

c)

Surface sloughing white layer

d)

Pain is completely absent

14.

Which healing pathway minimizes scar formation by closing clean wounds promptly?

a)

Keloid-prone route

b)

Tertiary intention route

c)

Primary intention route

d)

Secondary intention route

15.

During the acute inflammatory process, the second type of white blood cell to emigrate from the blood vessel into the injured tissue is termed

a)

macrophage

b)

neutrophil

c)

plasma cell

d)

lymphocyte

16.

The breakdown of cellular adhesion between epithelial cells is termed

a)

cell-mediated immunity

b)

Nikolsky sign

c)

acantholysis

d)

anaphylaxis

17.

In which type of immune response do B-lymphocytes and antibodies play the predominant role?

a)

Passive immunity

b)

Humoral immunity

c)

Immune complex

d)

Cell-mediated immunity

18.

Which is an example of type I hypersensitivity?

a)

Immune complexes formed between microorganisms and antibody in the circulating blood

b)

Asthma

c)

Serum sickness

d)

Autoimmune hemolytic anemia

19.

A prodromal period begins

a)

1 to 2 days before the onset of ulcers

b)

1 week before the onset of ulcers

c)

the day the ulcers erupt

20.

Sjögren syndrome is best described as a(n) ______.

a)

form of aphthous ulcers in the mouth

b)

autoimmune disease affecting salivary and lacrimal glands

c)

type of Langerhans cell disease variant

d)

allergic reaction to environmental antigens

21.

Treatment for pemphigus vulgaris primarily involves ______.

a)

long-term antiviral drug regimen

b)

broad-spectrum antibiotics course

c)

regular antihistamine therapy

d)

high doses of systemic corticosteroids

22.

Diagnosing Behçet syndrome generally requires which consideration?

a)

Two of the three principal manifestations

b)

The presence of all three manifestations

c)

A biopsy of an oral ulcer only

d)

A history of pemphigus vulgaris

23.

A condition with explosive onset featuring target (bull's eye) skin lesions and mucosal ulcerations of the lips, buccal mucosa, and tongue that may be ulcerated, encrusted, and bloody most likely indicates ______.

a)

Systemic lupus erythematosus

b)

Contact dermatitis

c)

Lichen planus

d)

Erythema multiforme

24.

For aphthous ulcers, diagnosis is based on distinctive clinical appearance, lesion location, and ______.

a)

serologic autoantibody panel

b)

response to antibiotics

c)

patient history

d)

patch test results

25.

A prodromal period of 7 to 10 days most closely precedes the eruption of which lesions?

a)

Erythema multiforme targets

b)

Lichen planus plaques

c)

Aphthous ulcers

d)

Herpetic vesicles

26.

Which statement best differentiates erythema multiforme lesions on the skin?

a)

Target, iris, or bull's eye appearance

b)

Uniform annular erythematous rings

c)

Scaly plaques with Wickham striae

d)

Nonulcerated maculopapular patches

27.

Which pair correctly matches disorder and primary therapy?

a)

Lichen planus — high-dose steroids

b)

Behçet syndrome — antivirals

c)

Sjögren syndrome — antibiotics

d)

Pemphigus vulgaris — systemic corticosteroids

28.

Which finding increases suspicion for Behçet syndrome during clinical evaluation?

a)

Exclusive salivary gland enlargement

b)

Isolated contact dermatitis on hands

c)

Single traumatic ulcer without eye signs

d)

Recurrent oral ulcers with ocular involvement

29.

Which feature is least consistent with erythema multiforme involving mucosa?

a)

Encrusted, bloody lesions on the lips

b)

Diffuse pruritic scaling without ulcers

c)

Ulcerations on the tongue

d)

Superficial ulcerations on buccal mucosa

30.

Which condition is associated with scarlet fever?

a)

Strawberry tongue

b)

Scrofula

c)

Median rhomboid glossitis

d)

Black hairy tongue

31.

The most common sites for oral lesions in tuberculosis are the

a)

floor and mucobuccal folds

b)

uvula and faucial pillars

c)

gingiva and lips

d)

tongue and palate

32.

Which statement is not true about syphilis?

a)

Dark-field exam can diagnose skin lesions

b)

Penicillin is standard treatment

c)

VDRL and FTA-ABS confirm diagnosis

d)

Antibody titer rises after successful therapy

33.

Which condition does not contribute to the overgrowth of Candida albicans?

a)

Dentures

b)

Angioedema

c)

Antibiotic therapy

d)

Cancer chemotherapy

34.

The varicella-zoster virus causes a highly contagious disease in children termed

a)

herpangina

b)

chickenpox

c)

shingles

d)

hand-foot-and-mouth

35.

Select the diagnostic test commonly used to confirm syphilis infection.

a)

Throat culture

b)

VDRL with FTA-ABS

c)

Complete blood count

d)

Tuberculin skin test

36.

Identify the oral site least likely to show tuberculosis lesions.

a)

Uvula

b)

Gingiva

c)

Palate

d)

Tongue

37.

Which oral condition presents as an elongated, darkly pigmented lingual filiform papillae?

a)

Geographic tongue

b)

Strawberry tongue

c)

Median rhomboid glossitis

d)

Black hairy tongue

38.

Which factor most predisposes to candidal overgrowth by altering normal flora?

a)

Fluoride use

b)

Mouth breathing

c)

Antibiotic therapy

d)

Topical steroids

39.

Which clinical feature characterizes scarlet fever in the oral cavity?

a)

Purulent gingival exudate

b)

Vesicular lip lesions

c)

Strawberry-appearing tongue

d)

Median rhomboid plaque

40.

Herpangina is caused by which virus?

a)

Varicella–zoster virus

b)

Epstein–Barr virus

c)

Coxsackievirus

d)

Herpes simplex virus

41.

In HIV infection, which test measures viral titer rather than circulating antibody?

a)

Western blot

b)

ELISA

c)

VDRL

d)

PCR

42.

In herpes labialis, the viral load is highest during which stage?

a)

Healing stage

b)

Crusted stage

c)

Prodromal stage

d)

Vesicle stage

43.

Unilateral vesicles along a sensory nerve distribution in an adult most suggest

a)

Minor aphthous ulcers

b)

Varicella–zoster or chickenpox

c)

Herpes zoster or shingles

d)

Recurrent intraoral herpes simplex

44.

Which diagnostic assay is primarily an antibody detection test for HIV?

a)

Western blot

b)

VDRL

c)

PCR

d)

ELISA

45.

A patient presents with fever and oral vesicles localized to the soft palate and tonsillar pillars. Which pathogen is the most likely cause?

a)

Herpes simplex type 2 infection

b)

Coxsackievirus infection

c)

Varicella–zoster reactivation

d)

Epstein–Barr virus infection

46.

During which phase of a cold sore is transmission risk greatest due to peak viral shedding?

a)

Resolution phase

b)

Vesicular phase

c)

Scabbing phase

d)

Prodromal phase

47.

Which condition typically presents bilaterally with diffuse lesions rather than unilateral dermatomal vesicles?

a)

Herpangina

b)

Aphthous ulcers

c)

Chickenpox (varicella)

d)

Herpes zoster

48.

Which test is confirmatory for HIV by detecting specific viral proteins?

a)

PCR

b)

ELISA

c)

VDRL

d)

Western blot

49.

Minor aphthous ulcers are best distinguished from herpetic lesions by which feature?

a)

Keratotic rim around vesicles

b)

Dermatomal unilateral distribution

c)

Occurrence on keratinized mucosa

d)

Shallow ulcers without vesicle stage

50.

The lesions seen in this illustration most commonly appear in patients with HIV. What is the clinical diagnosis?

a)

Aphthous ulcer

b)

Candidiasis

c)

Lymphoma

d)

Kaposi sarcoma

51.

Which form of candidiasis is most asymptomatic?

a)

Pseudomembranous

b)

Angular cheilitis

c)

Erythematous

d)

Chronic atrophic candidiasis

52.

An erythematous, often rhombus-shaped, flat-to-raised area on the midline of the posterior dorsal tongue describes

a)

hairy leukoplakia.

b)

geographic tongue.

c)

median rhomboid glossitis.

d)

recurrent herpes simplex infection.

53.

Why is hairy leukoplakia a significant clinical finding in persons with HIV disease?

a)

Its presence suggests poor oral hygiene

b)

It is considered a predictor of the development of AIDS

c)

Hairy leukoplakia may affect the function of the taste buds

d)

It may represent a malignancy of the tongue

54.

Intraoral lesions of Kaposi sarcoma are most often found in which two sites?

a)

Palate and gingiva

b)

Uvula and posterior third of the tongue

c)

Gingiva and floor of the mouth

d)

Labial mucosa and interdental papilla

55.

Which epithelium-lined tract represents a developmental anomaly located at the commissures of the mouth?

a)

Congenital lip pit

b)

Fistula

c)

Angular cheilitis

d)

Commissural lip pit

56.

The most common cyst in the oral cavity is caused by pulpal inflammation. What is it called?

a)

Primordial cyst

b)

Radicular cyst

c)

Eruption cyst

d)

Dentigerous cyst

57.

Radiographically, which radiolucent cyst is often heart shaped due to the anatomic Y-shaped area?

a)

Globulomaxillary cyst

b)

Nasopalatine canal cyst

c)

Median palatine cyst

d)

Nasolabial cyst

58.

Which pseudocyst filled with salivary gland tissue may be an extension of the sublingual gland?

a)

Globulomaxillary cyst

b)

Ranula

c)

Static bone cyst

d)

Lymphoepithelial cyst

59.

Identify the lesion type most associated with immunocompromised states and vascular proliferation in the oral cavity.

a)

Hemangioma

b)

Peripheral ossifying fibroma

c)

Kaposi sarcoma

d)

Pyogenic granuloma

60.

Which anatomical location is classically related to a nasopalatine canal cyst appearance on radiographs?

a)

Between maxillary lateral and canine roots

b)

Within mandibular body near premolars

c)

Floor of mouth anterior to sublingual caruncle

d)

Midline of the palate near incisive foramen

61.

A swelling in the floor of the mouth that transilluminates and is associated with mucus extravasation is most consistent with which diagnosis?

a)

Thyroglossal duct cyst

b)

Branchial cleft cyst

c)

Dermoid cyst

d)

Ranula

62.

Which cyst arises from inflammatory stimulation of epithelial rests of Malassez at the apex of a nonvital tooth?

a)

Primordial cyst

b)

Residual cyst

c)

Dentigerous cyst

d)

Radicular cyst

63.

Which developmental pit occurs at the lip commissure and may present as a small depression or tract?

a)

Angular cheilitis lesion

b)

Paramedian lip pit

c)

Median palatal pit

d)

Commissural lip pit

64.

The most common supernumerary tooth is termed

a)

distomolar.

b)

mesiodens.

c)

mulberry molar.

d)

Turner tooth.

65.

Dens in dente is a developmental anomaly often seen with

a)

supernumerary roots.

b)

extra cusps.

c)

a periapical lesion.

d)

tuberculated premolars.

66.

Which defines a disturbance of the maturation of the enamel matrix?

a)

Enamel hypocalcification

b)

Premature birth

c)

Mulberry molar

d)

Turner tooth

67.

Regional odontodysplasia is also referred to as

a)

supernumerary teeth.

b)

taurodontism.

c)

ghost teeth.

d)

hypodontia.

68.

Which term best describes a disorder caused by abnormalities in the genetic makeup transmitted from parent to offspring?

a)

Anomaly

b)

Inherited

69.

Odontogenic keratocysts are a clinical component of which syndrome?

a)

Gardner syndrome association

b)

nevoid basal cell carcinoma syndrome

c)

neurofibromatosis of von Recklinghausen

d)

cherubism syndrome presentation

70.

Primitive germ cells have how many chromosomes and are termed what?

a)

46; diploid

b)

23; haploid

c)

46; haploid

d)

23; diploid

71.

Most cases of Down syndrome are associated with which maternal factor?

a)

estrogen supplement exposure

b)

late maternal age at conception

c)

inhalation of volatile vapors

d)

maternal consumption of alcohol

72.

Patients with Turner syndrome typically have which phenotype and how many chromosomes?

a)

male; 47

b)

female; 46

c)

female; 45

d)

male; 44

73.

Cyclic neutropenia is characterized by what clinical course?

a)

episodes generally persisting for 21 to 27 days

b)

severe ulcerative gingivitis or gingivostomatitis

c)

lifelong remission after early childhood

d)

constant neutrophil elevation without cycles

74.

Which statement best distinguishes diploid from haploid human cells?

a)

haploid cells carry 22 autosomes only

b)

diploid cells carry 46 chromosomes total

c)

haploid cells carry 46 chromosomes total

d)

diploid cells carry 23 chromosomes total

75.

Which etiologic misconception about Down syndrome should be corrected?

a)

it mainly results from estrogen supplement exposure

b)

it mainly results from maternal alcohol consumption

c)

it primarily results from trisomy due to maternal age

d)

it mainly results from inhalation of volatile vapors

76.

Turner syndrome most commonly involves which chromosomal change?

a)

trisomy of sex chromosomes

b)

triploidy across all chromosomes

c)

monosomy X karyotype 45,X

d)

deletion of chromosome 21

77.

Which oral manifestation can accompany cyclic neutropenia during episodes?

a)

constant aphthous ulcers between cycles

b)

severe ulcerative gingivitis or gingivostomatitis

c)

enamel hypocalcification without inflammation

d)

painless mucosal hyperplasia without ulcers

78.

Cherubism is best categorized as which type of condition listed?

a)

congenital developmental anomaly

b)

acquired infectious disease

c)

autoimmune endocrine disorder

d)

environmental toxic exposure

79.

Cherubism is best described by which inheritance and penetrance pattern?

a)

Mitochondrial inheritance with uniform penetrance

b)

Autosomal-dominant with marked female penetrance

c)

Autosomal-recessive with complete male penetrance

d)

X-linked dominant with variable penetrance

80.

Which craniofacial region is most frequently involved in cherubism?

a)

Mandible involvement predominates

b)

Zygomatic bone predominates

c)

Frontal bone predominates

d)

Maxilla involvement predominates

81.

Radiographs of cherubism typically show what pattern?

a)

Soap-bubble multilocular appearance

b)

Ground-glass monolocular opacity

c)

Sunburst periosteal reaction

d)

Punched-out unilocular defects

82.

Which facial presentation aligns with cherubism?

a)

Isolated orbital rim thickening typical

b)

Midline nasal collapse typical

c)

Bilateral symmetric swelling typical

d)

Unilateral facial deformity typical

83.

Ellis–van Creveld syndrome most likely presents with which limb finding?

a)

Polydactyly on radial forearm side

b)

Syndactyly on ulnar forearm side

c)

Absent thumb on radial side

d)

Hyperextension of wrist joints

84.

Which oral vestibular feature is absent in Ellis–van Creveld syndrome?

a)

Posterior mandibular vestibular sulcus absent

b)

Buccal maxillary vestibule absent

c)

Anterior maxillary vestibular sulcus absent

d)

Labial mandibular vestibule absent

85.

In hereditary hemorrhagic telangiectasia, oral telangiectasias are especially prominent at which site?

a)

Buccal mucosa near commissure

b)

Attached gingiva around molars

c)

Hard and soft palate surfaces

d)

Tip and anterior dorsum of tongue

86.

Multiple melanotic macular pigmentations of skin and mucosa with gastrointestinal polyposis characterize which syndrome?

a)

Carney complex type 2

b)

Gardner syndrome variant

c)

Peutz–Jeghers syndrome

d)

Osler–Rendu–Parkes Weber syndrome

87.

A chromosomal deletion on the long arm of chromosome 11 regions 14–21 is most consistent with which inheritance?

a)

Autosomal recessive inheritance

b)

X-linked recessive inheritance

c)

Autosomal dominant inheritance

d)

Mitochondrial inheritance

88.

Which vascular condition corresponds to mucosal telangiectasias and epistaxis risk?

a)

Osler–Rendu–Parkes Weber syndrome

b)

Ehlers–Danlos type IV

c)

Peutz–Jeghers syndrome

d)

Marfan vascular variant

89.

Snow-capped amelogenesis imperfecta is a variation of type ____ amelogenesis imperfecta.

a)

hypoplastic–hypomaturation

b)

hypomaturation

c)

hypocalcified

d)

hypoplastic

90.

Frontal bossing, depressed nasal bridge, protuberant lips, and near absence of scalp hair are most characteristic of which condition?

a)

Hypophosphatemic vitamin D–resistant rickets

b)

Hypophosphatasia

c)

Hypohidrotic ectodermal dysplasia

d)

Dentin dysplasia

91.

A benign tumor of bone is best termed a(n) ____.

a)

osteogenic sarcoma

b)

carcinoma

c)

osteoma

d)

chondroma

92.

A papilloma is a ____ tumor derived from ____ epithelium.

a)

malignant; odontogenic

b)

benign; salivary gland

c)

malignant; squamous

d)

benign; squamous

93.

Which syndrome name appears alongside Van der Woude syndrome in the list?

a)

Ehlers–Danlos syndrome

b)

Marfan syndrome

c)

Gorlin syndrome

d)

Turner syndrome

94.

Which listed condition is a malignant bone tumor?

a)

osteogenic sarcoma

b)

osteoma

c)

chondroma

d)

papilloma

95.

Which option pairs a tumor type with a tissue of origin that does NOT match a papilloma?

a)

benign; salivary gland

b)

benign; squamous

c)

malignant; squamous

d)

malignant; odontogenic

96.

Which dental condition listed is primarily a disorder of dentin formation?

a)

Gorlin syndrome

b)

Hypophosphatasia

c)

Hypohidrotic ectodermal dysplasia

d)

Dentin dysplasia

97.

Which metabolic or mineralization disorder is associated with low alkaline phosphatase activity?

a)

Hypophosphatasia

b)

Osteogenic sarcoma

c)

Hypophosphatemic vitamin D–resistant rickets

d)

Hypohidrotic ectodermal dysplasia

98.

Which craniofacial feature combination would most strongly suggest ectodermal dysplasia?

a)

Proptosis with midface hypoplasia

b)

Frontal bossing with depressed nasal bridge

c)

Mandibular prognathism with microtia

d)

Cleft palate with macroglossia

99.

Squamous cell carcinoma of the oral epithelium usually metastasizes first to which site?

a)

Lymph nodes

b)

Liver

c)

Lungs

d)

Spleen

100.

“Keratin pearls” are a characteristic feature of

a)

squamous cell carcinoma.

b)

monomorphic adenoma.

c)

pleomorphic adenoma.

d)

basal cell carcinoma.

101.

Basal cell carcinoma is a ____ tumor that ____ in the oral cavity.

a)

malignant; does not occur

b)

benign; does not occur

c)

malignant; occurs

d)

benign; occurs

102.

Which is the most common salivary gland neoplasm?

a)

Adenoid cystic carcinoma

b)

Mucoepidermoid carcinoma

c)

Monomorphic adenoma

d)

Pleomorphic adenoma

103.

Which is the most common malignant salivary gland tumor found in children?

a)

Mucoepidermoid carcinoma

b)

Adenoid cystic carcinoma

104.

Which statement about ameloblastoma is correct?

a)

May cause expansion of bone

b)

Is commonly known as a Pindborg tumor

c)

Is a benign, encapsulated tumor

d)

Occurs exclusively in the mandible

105.

Ghost cells are characteristic of which lesion?

a)

Adenomatoid odontogenic tumor

b)

Calcifying epithelial odontogenic tumor

c)

Ameloblastoma

d)

Calcifying odontogenic cyst

106.

Which description best matches a compound odontoma?

a)

Usually occurs in the posterior mandible

b)

Appears as radiolucent mass surrounded by thin radiopaque halo

c)

Mass of enamel, dentin, cementum, and pulp not resembling a normal tooth

d)

Radiograph shows cluster of miniature teeth with radiolucent halo

107.

The central cemento-ossifying fibroma is most likely derived from which cells?

a)

Cells of the periodontal ligament

b)

Osteoblasts

c)

Odontoblasts

d)

Ameloblasts

108.

Which statement about lipoma is correct?

a)

Is a benign tumor of adipose tissue

b)

Is a tumor of peripheral nerve tissue

c)

Is a malignant tumor of skeletal muscle

d)

Is commonly encapsulated by enamel-like tissue

109.

Which lesion is referred to as Pindborg tumor?

a)

Ameloblastoma

b)

Pleomorphic adenoma

c)

Monomorphic adenoma

d)

Calcifying epithelial odontogenic tumor

110.

Which tumor type is most associated with salivary glands and shows mixed cellular morphology?

a)

Ameloblastoma

b)

Lipoma

c)

Pleomorphic adenoma

d)

Monomorphic adenoma

111.

Which feature would argue against a benign encapsulated tumor diagnosis for ameloblastoma?

a)

Slow growth pattern

b)

Origin from salivary gland tissue

c)

Encapsulation by a fibrous capsule

d)

Tendency to cause bone expansion

112.

In radiographic evaluation, which finding supports diagnosing a compound odontoma?

a)

Multilocular radiolucency with soap-bubble appearance

b)

Diffuse radiopacity without defined borders

c)

Cluster of small tooth-like structures with radiolucent halo

d)

Single radiolucent area with thin radiopaque rim

113.

Which cell type primarily forms dentin and is therefore not the origin of central cemento-ossifying fibroma?

a)

Periodontal ligament fibroblasts

b)

Odontoblasts

c)

Osteoblasts

d)

Ameloblasts

114.

Which statement about hemangiomas is true?

a)

They may occur in adults after trauma as abnormal vessel proliferation

b)

They are more common in boys than in girls

c)

The gingiva is the most common intraoral location

d)

They appear as deep red or blue lesions that do not blanch

115.

Kaposi sarcoma is

a)

a malignant striated muscle tumor

b)

caused by a human herpesvirus

c)

seen only in association with HIV infection

d)

most often seen intraorally on the tongue

116.

Which statement about malignant melanoma is true?

a)

The most common intraoral location is the tongue

b)

Most cases arise from prolonged exposure to benzene

c)

It has a benign counterpart called benign melanoma

d)

Primary malignant melanoma of the oral cavity is rare

117.

Which statement is true of periapical cemento-osseous dysplasia?

a)

It is a neoplasm

b)

The lesion is painful and often in the posterior maxilla

c)

Teeth in the area are usually not vital

d)

Older lesions are primarily radiopaque

118.

Surgical treatment would most likely be recommended for a patient with ______ dysplasia.

a)

focal cemento-osseous

b)

florid cemento-osseous

c)

periapical cemento-osseous

d)

fibrous

119.

A hemangioma typically appears clinically as

a)

a bluish mass surfaced by thick keratin

b)

a yellowish mass surfaced by thin epithelium

c)

a firm white nodule with smooth surface

d)

a papillary mass with ulcerated surface

120.

Hemangiomas are found most commonly intraorally on the

a)

hard palate

b)

gingiva

c)

tongue

d)

buccal mucosa

121.

Hemangiomas occur most often in

a)

men over 60

b)

girls over 15

c)

women under 40

d)

boys under 10

122.

Kaposi sarcoma is best characterized as

a)

an epithelial dysplasia of keratinocytes

b)

a vascular neoplasm linked to HHV-8

c)

a muscle tumor derived from myocytes

d)

a granulomatous inflammatory process

123.

In periapical cemento-osseous dysplasia, a common finding is

a)

nonvital teeth adjacent to radiolucent lesions

b)

vital teeth with evolving radiolucent-to-radiopaque changes

c)

painful swelling with cortical perforation

d)

lesions confined to the posterior maxilla

124.

Which pattern best matches monostotic fibrous dysplasia in the maxillofacial region?

a)

Typically diagnosed in middle-aged women

b)

Commonly painless buccal plate bulging orally

c)

Expanding lesion causing malocclusion or tooth displacement

d)

Involves multiple bones in most cases

125.

Paget disease of bone in the jaws most commonly shows which radiographic feature?

a)

Cotton-wool appearance on radiographs

b)

Ground-glass appearance throughout bone

c)

Uniform lamellar bone radiodensity

d)

Sunburst spiculations from cortex

126.

Which statement about Paget disease of bone is accurate for clinical presentation?

a)

Primarily affects only a single craniofacial bone

b)

Consistently results in bone shrinkage

c)

Often presents without pain symptoms

d)

Typically occurs in children under 18 years

127.

Numerous gritty pieces of soft and hard tissue containing fibrous connective tissue interspersed with bone trabeculae and cementum-like material are most characteristic of which condition?

a)

Central cementifying fibroma

b)

Ossifying fibroma

c)

Florid cemento-osseous dysplasia

d)

Focal cemento-osseous dysplasia

128.

Which description aligns with buccal plate changes observed orally in monostotic fibrous dysplasia?

a)

Painful bulging of the buccal plate

b)

Localized ulceration over buccal plate

c)

Nonexpansile thinning of the buccal plate

d)

Expansile swelling displacing adjacent teeth

129.

Which variant names correspond to cemento-osseous dysplasia subtypes?

a)

Periapical, focal, florid

b)

Central, peripheral, florid

c)

Monostotic, polyostotic, focal

d)

Trabecular, cemental, combined

130.

Giant cell granulomas located in gingiva or alveolar mucosa are termed what?

a)

Ossifying fibromatous granulomas

b)

Reactive hyperplastic granulomas

c)

Peripheral giant cell granulomas

d)

Central giant cell granulomas

131.

Giant cell granulomas within the maxilla or mandible are classified as what type?

a)

Peripheral lesions

b)

Central lesions

c)

Odontogenic stromal lesions

d)

Reactive periodontal lesions

132.

Which outcome is least consistent with Paget disease of bone affecting the jaws?

a)

Shrinkage of affected bone volume

b)

Involvement in adults rather than children

c)

Cotton-wool radiographic appearance

d)

Painless presentation in many cases

133.

Which feature of the expanding lesion in fibrous dysplasia most directly impacts occlusion?

a)

Induces malocclusion by tooth displacement

b)

Leads to enamel hypoplasia patterns

c)

Produces periodontal pocketing only

d)

Causes tooth ankylosis without movement

134.

“Ground glass” is the classic radiographic description of which condition?

a)

Fibrous dysplasia

b)

Florid cemento-osseous dysplasia

c)

Paget disease of bone

d)

Osteomalacia

135.

Which statement best differentiates periapical cemento-osseous dysplasia from florid cemento-osseous dysplasia?

a)

Florid form involves multiple quadrants including posterior mandible

b)

Periapical form affects only whites while florid affects all groups

c)

Symptoms are uniformly painful in both conditions

d)

Radiographic appearances are identical for both conditions

136.

Which feature is NOT characteristic of polyostotic fibrous dysplasia?

a)

Male predilection

b)

Occurs in children under 10 years

c)

Seen in association with skin lesions

d)

Most cases are asymptomatic

137.

Periapical cemento-osseous dysplasia typically shows which demographic pattern?

a)

Predominantly elderly patients

b)

Equal across all ethnicities

c)

Predominantly black females

d)

Predominantly white males

138.

Which region is commonly involved in florid cemento-osseous dysplasia?

a)

Anterior maxilla only

b)

Condyle and coronoid process only

c)

Single periapical site in premolar area

d)

Posterior mandible among multiple quadrants

139.

What is a typical symptom profile for fibrous dysplasia?

a)

Intermittent febrile episodes

b)

Most patients asymptomatic

c)

Neurologic deficits common

d)

Frequently severe pain

140.

Skin lesions classically associated with polyostotic fibrous dysplasia are best described as which finding?

a)

Livedo reticularis

b)

Targetoid lesions

c)

Erythematous plaques

d)

Café-au-lait macules

141.

Paget disease of bone typically presents radiographically with which pattern?

a)

Sunburst periosteal reaction

b)

Cotton wool appearance in later stages

c)

Moth-eaten lytic destruction

d)

Uniform ground glass texture

142.

Which statement about the pain spectrum in cemento-osseous dysplasia is accurate?

a)

Pain occurs only with superimposed caries

b)

Never associated with pain

c)

Ranges from asymptomatic to painful

d)

Always extremely painful

143.

The most common cause of hyperpituitarism is which lesion?

a)

Craniopharyngioma

b)

Pituitary adenoma

c)

Hypothalamic hamartoma

d)

Meningioma of sella

144.

The most common cause of hyperthyroidism is

a)

hyperplasia of the thyroid gland tissue

b)

benign and malignant thyroid tumors

c)

pituitary gland disease affecting TSH

d)

an autoimmune disorder targeting receptors

145.

Which statement about type 1 diabetes is true?

a)

It can present with polydipsia, polyuria, polyphagia

b)

Onset is gradual and occurs after age forty

c)

About 30% of patients with diabetes have type 1

d)

It is called non–insulin-dependent diabetes mellitus

146.

Pernicious anemia results from deficiency of intrinsic factor secreted by which cells?

a)

beta cells of the pancreatic islets

b)

parietal cells of the stomach mucosa

c)

the gallbladder epithelial cells

d)

the adrenal cortical cells

147.

A megaloblastic anemia is characterized by red blood cells that are

a)

hypochromic and macrocytic in appearance

b)

hyperchromic and macrocytic in appearance

c)

microcytic and have retained nuclei

d)

macrocytic and have retained nuclei

148.

Thalassemia is best described as

a)

caused by folate deficiency impairing DNA

b)

caused by an abnormal type of hemoglobin

c)

caused by iron absorption defects in gut

d)

caused by autoimmune destruction of RBCs

149.

In type 1 diabetes, which pathophysiologic mechanism is primary?

a)

Autoimmune destruction of beta cells

b)

Peripheral resistance to insulin signaling

c)

Excess hepatic glucose production

d)

Mutations in insulin receptor gene