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Tropmed 1

Total questions: 94

Worksheet time: 47mins

Name
Class
Date
1.

A 22-year-old woman comes to the ED with high fever for 3 days accompanied by nausea and generalized joint pain. Vital signs: BP 110/80 mmHg, HR 100/min, RR 18/min. Laboratory: Hb 12 g/dL, leukocytes 7,000/mm3, platelets 124,000/mm3, Hct 40%, NS1 positive. Tourniquet test positive and petechiae are found on both hands. What is the most appropriate diagnosis for this patient?

a)

Dengue fever

b)

Dengue hemorrhagic fever (DHF) grade I

c)

DHF grade II

d)

DHF grade III

e)

DHF grade IV

2.

A 9-year-old girl presents to the ED with high fever for 4 days, complaining of dizziness and nausea. Physical exam shows vital signs within normal limits. Rumple-Leede test is positive. Laboratory: Hb 13 g/dL, Hct 47%, leukocytes 6,500/mm3, platelets 89,000/mm3. What is the diagnosis in this case?

a)

Dengue fever

b)

Dengue hemorrhagic fever grade I

c)

Dengue hemorrhagic fever grade II

d)

Dengue hemorrhagic fever grade III

e)

Dengue hemorrhagic fever grade IV

3.

A 25-year-old man presents to the ED with high fever for 3 days accompanied by nausea and generalized joint pain. Physical exam reveals petechiae on both hands. Vital signs: BP 110/70 mmHg, HR 100/min, RR 20/min. Laboratory: Hb 13 g/dL, leukocytes 5,000/mm3, platelets 98,000/mm3, NS1 positive. Chest X-ray suggests bilateral pleural effusion. What is the most appropriate diagnosis for this patient?

a)

Dengue fever

b)

DHF grade I

c)

DHF grade II

d)

DHF grade III

e)

DHF grade IV

4.

A 12-year-old boy named Wahyu presents to the ED with high fever for 4 days. Physical exam reveals petechiae on the arms and trunk. Vital signs: HR 120/min, BP 80/50 mmHg, RR 20/min, temperature 38.6°C. Laboratory: Hb 12 g/dL, hematocrit 48%, leukocytes 2,300/mm3, platelets 23,000/mm3. What is the diagnosis for this patient?

a)

DHF grade I

b)

DHF grade II

c)

DHF grade III

d)

DHF grade IV

e)

Dengue fever

5.

A 25-year-old man is brought to the ED with decreased consciousness for 1 hour. Family reports high fever for 4 days with arthralgia and prior vomiting. Vital signs: BP unmeasurable, pulse not palpable, RR 15/min, temperature 38.0°C. Physical exam: enlarged liver, cold and clammy extremities. Laboratory: Hb 15.1 g/dL, hematocrit 52%, leukocytes 2,500/mm3, platelets 35,000/mm3, Dengue IgM positive. What is the diagnosis?

a)

DHF grade I

b)

DHF grade II

c)

DHF grade III

d)

DHF grade IV

e)

Dengue fever

6.

A 21-year-old woman is brought to the ED unconscious. Five days earlier she had high fever with arthralgia, nausea, and two days ago had epistaxis. Physical exam: palpated BP 90 mmHg, pulse 120/min fast and weak, RR 28/min, temperature 37.1°C, cold extremities, pale skin. What is the most appropriate diagnosis for this case?

a)

Chikungunya fever

b)

Typhoid fever

c)

Meningitis

d)

Encephalitis

e)

Dengue shock syndrome

7.

A 25-year-old man presents to a clinic with high fever for 3 days, persistent and rising. Complaints include arthralgia and retro-orbital pain. No epistaxis. Physical exam: BP 100/70 mmHg, HR 90/min, RR 20/min, temperature 39°C; liver palpable 1 cm below the costal margin. Laboratory: Hb 11 g/dL, leukocytes 4,000/mm3, platelets 60,000/mm3, Hct 42%. What is the next recommended diagnostic test?

a)

NS1 antigen

b)

Anti-dengue IgM/IgG serology

c)

Complete urinalysis

d)

Peripheral blood smear

e)

Routine complete blood count

8.

A 25-year-old man presents to a clinic with high fever for 5 days, persistent and rising. Complaints include arthralgia and retro-orbital pain. No epistaxis. Physical exam: BP 100/70 mmHg, HR 90/min, RR 22/min, temperature 39°C; liver palpable 1 cm below the costal margin. Laboratory: Hb 11 g/dL, leukocytes 4,000/mm3, platelets 60,000/mm3, Hct 42%. What is the next recommended diagnostic test?

a)

NS1 antigen

b)

Anti-dengue IgM/IgG serology

c)

Complete urinalysis

d)

Peripheral blood smear

e)

Routine complete blood count

9.

Mr. Jonathan, 28 years old, presents with fatigue. Two days prior he had high fever, vomiting, and headache, and now epistaxis. Vital signs: BP 100/70 mmHg, HR 90/min, RR 22/min, temperature 39°C. Routine labs: Hb 11 g/dL, hematocrit 48%, platelets 89,000/mm3. What serologic dengue result is most likely?

a)

NS1 positive, IgG positive, IgM positive

b)

NS1 positive, IgG negative, IgM negative

c)

NS1 positive, IgG positive, IgM negative

d)

NS1 negative, IgG negative, IgM positive

e)

NS1 negative, IgG positive, IgM positive

10.

A 25-year-old man presents to the ED with high fever for 3 days accompanied by nausea and generalized joint pain. Vital signs: BP 110/70 mmHg, HR 100/min, RR 20/min. Laboratory: Hb 13 g/dL, leukocytes 5,000/mm3, platelets 110,000/mm3, Hct 40%. NS1 is positive. What is the most appropriate management?

a)

Inpatient care + paracetamol + domperidone + Ringer lactate infusion

b)

Outpatient care + paracetamol + domperidone + oral fluids + antibiotics

c)

Inpatient care + paracetamol + domperidone + intravenous colloid

d)

Inpatient care + paracetamol + domperidone + intravenous crystalloid + antibiotics

e)

Outpatient care + paracetamol + oral fluids + domperidone

11.

Lisa, 12 years old, is brought to the ED with epistaxis for 2 hours. She has had high fever for 2 days. Vital signs: conscious, BP 100/70 mmHg, pulse 110/min, RR 18/min, temperature 38°C; extremities warm. Physical exam shows bleeding from the nose and gums and petechiae. Laboratory: Hb 9 g/dL, leukocytes 4,800/mm3, platelets 66,000/mm3, anti-dengue IgM negative, IgG positive. What is the appropriate management?

a)

IV Ringer lactate 7 mL/kg/hour

b)

IV Ringer lactate 20 mL/kg/hour

c)

IV colloid 10 mL/kg every 15 minutes

d)

IV D5%

e)

Adequate oral fluids

12.

A 35-year-old woman presents to the ED with complaints of high fever for 4 days accompanied by epistaxis, nausea, and vomiting. Vital signs: BP 100/60 mmHg, pulse 84/min, RR 18/min, temperature 37.5°C; extremities warm. Body weight is reported as 50 kg. Laboratory: Hb 14.9 g/dL, leukocytes 3,500/mm3, platelets 55,000/mm3, Hct 51%. What is the most appropriate management for this patient?

a)

Ringer lactate infusion 300–350 mL over 30 minutes

b)

Ringer lactate infusion 300–350 mL over 1 hour

c)

Asering infusion 675–900 mL over 30 minutes

d)

Asering infusion 500–750 mL over 1 hour

e)

D10 infusion 250–450 mL over 1 hour

13.

Ms. Merry, 21 years old, presents to the ED with high fever. She had high fever starting 4 days ago, then the temperature dropped below normal; three days later the fever rose again and returned to normal. Complaints include headache, nausea, and joint pain. What fever pattern is being experienced?

a)

Continuous

b)

Remittent

c)

Intermittent

d)

Step-ladder pattern

e)

Saddleback

14.

A 25-year-old man presents to a primary care clinic with fever for 5 days that is persistent and continuous, accompanied for the past 3 days by nausea and vomiting 2–3 times/day. He reports headache, myalgia, and fatigue, without cough or rhinorrhea. Bowel and urinary habits are normal. Physical exam: BP 80/50 mmHg, pulse 108/min, temperature 37.6°C, epigastric tenderness, petechiae on both extremities. Laboratory: Hct 55%, platelets 45,000/mm3. What is the most appropriate therapy?

a)

Ringer lactate infusion

b)

Supplemental oxygen

c)

Antibiotics

d)

Antiemetic medication

e)

Platelet transfusion

15.

Mr. Dani, 35 years old, presents to a clinic with fever for 4 days accompanied by chills. He has taken antipyretics; fever decreases but recurs. Vital signs: BP 120/80 mmHg, pulse 100/min, RR 21/min, temperature 38°C. A peripheral smear shows a "starry sky" appearance and crescent-shaped forms. What is the diagnosis?

a)

Malaria falciparum

b)

Malaria tertiana

c)

Malaria quartana (malariae)

d)

Malaria vivax

e)

Malaria quartana (four-day fever)

16.

Ms. Sakura, 26 years old, presents with fever that occurs only every fourth day and is accompanied by chills and decreased appetite. Vital signs: BP 110/80 mmHg, pulse 110/min, RR 20/min, temperature 38°C. Peripheral smear shows erythrocytes of normal size with rosette-like forms and irregular edges. What is the most likely diagnosis?

a)

Malaria tropicana (falciparum)

b)

Malaria quartana (malariae)

c)

Malaria tertiana

d)

Malaria vivax

e)

Malaria ovale

17.

Mr. Fikri, 25 years old, presents to a rural clinic with intermittent fever and chills for 5 days. He also experiences nausea, vomiting, and myalgia. Vital signs: BP 110/80 mmHg, pulse 88/min, RR 20/min, temperature 39.2°C. Peripheral smear shows red blood cells of normal size with coarse stippling in the cytoplasm and basket-form trophozoites. What is the most likely causative species?

a)

Plasmodium vivax

b)

Plasmodium falciparum

c)

Plasmodium malariae

d)

Plasmodium ovale

e)

Mixed Plasmodium infection

18.

A 46-year-old man presents with intermittent high fever for 8 days accompanied by profuse sweating. Vital signs: blood pressure 110/80 mmHg, heart rate 104/min, respiratory rate 20/min, temperature 38.6 °C. Physical exam: pale conjunctivae, icteric sclerae, no neck stiffness, liver palpable 4 cm below costal margin, spleen Schüffner grade 2. Peripheral blood smear shows parasites with a ribbon-like band form inside erythrocytes. What is the causative species?

a)

Plasmodium vivax

b)

Plasmodium falciparum

c)

Plasmodium ovale

d)

Plasmodium malariae

e)

Plasmodium knowlesi

19.

A 30-year-old woman has 3 days of chills and fever. She traveled to Papua several weeks ago. Vital signs: blood pressure 110/70 mmHg, heart rate 88/min, respiratory rate 20/min, temperature 38 °C. Physical exam: anemic conjunctivae, hepatosplenomegaly. Peripheral smear shows ring forms with accolé forms (appliqué forms) on erythrocyte membranes. What is the most likely diagnosis?

a)

Tertian malaria

b)

Quartan malaria

c)

Malaria ovale

d)

Malaria tropicana (falciparum)

e)

Malaria vivax

20.

A 32-year-old man named Galih is brought to the emergency department with coma after 2 weeks of fever, chills, and night sweats while working in Papua. Vital signs: blood pressure 100/70 mmHg, pulse 60/min and weak/irregular, respiratory rate 20/min, temperature 38.0 °C. A peripheral blood smear image is provided. What is the most likely diagnosis?

a)

Cerebral malaria

b)

Algid malaria

c)

Malaria with hemoglobinuria

d)

Tertian malaria

e)

Quartan malaria

21.

A 32-year-old man presents with 2 weeks of fever, chills, and sweating after returning from East Nusa Tenggara (NTT). Vital signs: blood pressure 110/80 mmHg, temperature 38.3 °C, anemic conjunctivae. Laboratory: Hb 10 g/dL, platelets 235,000/µL, leukocytes 7,000/µL. Which supporting examination should be performed to establish malaria diagnosis in this patient?

a)

Dark-field microscopy

b)

Peripheral blood smear at night between 22:00–02:00

c)

IgM anti-dengue serology

d)

Rapid diagnostic test only

e)

Thick and thin peripheral blood smear

22.

A 21-year-old man is brought to the ED with agitation and decreased consciousness after a week of fever, chills, and cold sweats. Vital signs: GCS E2V3M4; blood pressure 100/80 mmHg; pulse 88/min; respiratory rate 24/min; temperature 38.3 °C. Peripheral smear shows a banana-shaped parasite within erythrocytes. In which developmental stage is this finding observed?

a)

Ring stage

b)

Trophozoite

c)

Schizont

d)

Gametocyte

e)

Young trophozoite

23.

A 40-year-old man is brought to the ED with decreased consciousness for 1 hour and high fever. Two weeks earlier he traveled to Sumba, NTT. Findings: GCS E1V1M1; blood pressure 110/80 mmHg; heart rate 102/min; respiratory rate 20/min; temperature 39.4 °C; icteric sclerae. Peripheral smear shows erythrocytes containing more than one parasite with a headphone-like appearance. What is the most accurate diagnosis?

a)

Uncomplicated malaria

b)

Malaria tropicana (falciparum)

c)

Severe malaria

d)

Tertian malaria

e)

Quartan malaria

24.

A 32-year-old man presents with 2 weeks of fever, chills, and sweating after returning from NTT. Vital signs: blood pressure 110/80 mmHg, temperature 38.3 °C, anemic conjunctivae. Laboratory: Hb 10 g/dL, platelets 235,000/µL, leukocytes 7,000/µL. Peripheral smear of the blood shows comet-shaped infected erythrocytes with James dots. What is the most appropriate diagnosis?

a)

Malaria falciparum

b)

Malaria ovale

c)

Malaria tropicana

d)

Malaria malariae

e)

Malaria knowlesi

25.

A 4-year-old boy living in Papua has had fluctuating fever for 2 weeks with diffuse body aches, nausea, and poor appetite. He appears ill and anemic. Laboratory: Hb 9.1 g/dL; Widal negative. Thick and thin blood smear image is provided. What is the most likely diagnosis?

a)

Typhoid fever

b)

Tertian malaria

c)

Trichomoniasis

d)

Amoebiasis

e)

Quartan malaria

26.

A 22-year-old pregnant woman (G1P0A0) at 10 weeks presents with 1 week of fever with chills and sweating after visiting her husband working in NTT 1 month ago. Vital signs: temperature 38.1 °C, blood pressure 110/70 mmHg, pulse 88/min, respiratory rate 20/min. Laboratory: Hb 10 g/dL, leukocytes 6,000/µL, platelets 180,000/µL. Peripheral smear shows more than one ring form in a single erythrocyte and a sausage-shaped parasite. What therapy should be given?

a)

Dihydroartemisinin–piperaquine (DHP) for 3 days plus primaquine for 1 day

b)

Dihydroartemisinin–piperaquine (DHP) for 3 days

c)

Quinine plus clindamycin for 3 days

d)

Dihydroartemisinin–piperaquine (DHP) for 3 days plus primaquine for 14 days

e)

Artesunate plus amodiaquine for 3 days

27.

A 30-year-old woman presents with 3 days of chills and fever after travel to Papua. Vital signs: blood pressure 110/70 mmHg, heart rate 88/min, respiratory rate 20/min, temperature 38 °C; anemic conjunctivae and hepatosplenomegaly. Peripheral smear shows ring forms with accolé (appliqué) forms. What is the appropriate first-line therapy?

a)

Dihydroartemisinin–piperaquine (DHP) for 3 days plus primaquine for 1 day

b)

Quinine for 7 days plus primaquine for 7 days plus doxycycline for 7 days

c)

Dihydroartemisinin–piperaquine (DHP) for 3 days plus primaquine for 14 days

d)

Quinine for 7 days plus primaquine for 14 days plus doxycycline for 7 days

e)

Quinine for 14 days plus primaquine for 14 days

28.

A 32-year-old man presents to a health center with 2 weeks of fever with chills and sweating after traveling to Raja Ampat 1 month earlier. Vital signs: temperature 38.5 °C, blood pressure 110/70 mmHg, pulse 88/min, respiratory rate 20/min. Laboratory: Hb 9.8 g/dL, leukocytes 6,000/µL, platelets 180,000/µL. Peripheral smear shows amoeboid ring forms with enlarged erythrocytes. What is the appropriate first-line therapy?

a)

Quinine for 7 days plus primaquine for 14 days

b)

Dihydroartemisinin–piperaquine (DHP) for 3 days plus primaquine for 1 day

c)

Quinine for 7 days plus primaquine for 7 days plus doxycycline for 7 days

d)

Dihydroartemisinin–piperaquine (DHP) for 3 days plus primaquine for 14 days

e)

Artesunate plus DHP for 3 days

29.

A 45-year-old man presents to the ED with dark-colored urine for 3 days and a preceding week of fever with chills and sweating. Physical exam: anemic conjunctivae, icteric sclerae, hepatosplenomegaly. Vital signs: temperature 38 °C; blood pressure 110/70 mmHg; heart rate 120/min; respiratory rate 18/min. A peripheral blood smear image is provided. What is the most appropriate management right now?

a)

Dihydroartemisinin–piperaquine (DHP) for 3 days

b)

DHP for 3 days plus primaquine for 1 day

c)

DHP for 3 days plus primaquine for 14 days

d)

Intravenous artesunate

e)

Doxycycline 100 mg twice daily for 7 days

30.

The same 32-year-old man with amoeboid ring forms in enlarged erythrocytes on peripheral smear (suggestive of Plasmodium vivax) requires second-line therapy. Vital signs and laboratory findings remain: temperature 38.5 °C; blood pressure 110/70 mmHg; pulse 88/min; respiratory rate 20/min; Hb 9.8 g/dL; leukocytes 6,000/µL; platelets 180,000/µL. Which second-line regimen should be given?

a)

Quinine for 7 days plus primaquine for 14 days

b)

Dihydroartemisinin–piperaquine (DHP) for 3 days plus primaquine for 1 day

c)

Quinine for 7 days plus primaquine for 7 days plus doxycycline for 7 days

d)

Dihydroartemisinin–piperaquine (DHP) for 3 days plus primaquine for 14 days

e)

Artesunate plus DHP for 3 days

31.

A 46-year-old man has had high fever for 10 days with profuse sweating after returning from Nias Island. Physical exam: pale conjunctivae, icteric sclerae; no neck stiffness; liver non-palpable; spleen Schüffner grade 2. Peripheral smear image is provided. What is the causative species?

a)

Plasmodium falciparum

b)

Plasmodium vivax

c)

Plasmodium ovale

d)

Plasmodium malariae

e)

Plasmodium knowlesi

32.

What is the appropriate management for the patient?

a)

DHP for 3 days plus primaquine for 1 day

b)

DHP for 3 days plus primaquine for 14 days

c)

DHP for 3 days

d)

Quinine pills plus clindamycin

e)

Doxycycline

33.

A 7-year-old child will move with the family to Papua and accompany them. What is the correct malaria prophylaxis for this child?

a)

Primaquine

b)

Quinine

c)

Artesunate

d)

Artemisinin

e)

Mefloquine

34.

A 45-year-old woman is preparing to work in Flores and consults on preventing malaria. The area she will visit remains chloroquine-sensitive. Which prophylaxis is appropriate to give before departure?

a)

Doxycycline 100 mg/day for 2 weeks before departure

b)

Primaquine 2×15 mg/day for 1 week before departure

c)

Chloroquine 300 mg/week starting 1 week before departure

d)

Chloroquine 300 mg/day for 4 weeks before departure

e)

Chloroquine 300 mg immediately before travel

35.

A 30-year-old man has had fever for 1 week with yellow eyes and muscle pain. He volunteered in a village affected by flooding for 2 weeks. He reports dark urine and bilateral gastrocnemius tenderness. Labs: Hb 11.2 g/dL, leukocytes 17,000 (neutrophils 90%), urea 87 mg/dL, creatinine 3.25 mg/dL. Urinalysis: erythrocytes 3+, leukocytes 2+. What is the diagnosis?

a)

Waterborne infection

b)

Weil’s disease

c)

Leptospirosis

d)

Plague

e)

Chikungunya

36.

A 40-year-old farmer has fever for 5 days and generalized body aches. He works in rice fields and rarely uses footwear. Physical exam shows gastrocnemius tenderness without icteric sclera. Labs: urea 22 mg/dL, creatinine 0.9 mg/dL. What is the most appropriate diagnosis?

a)

Balantidiasis

b)

Amoebiasis

c)

Leptospirosis

d)

Weil’s disease

e)

Hepatitis A

37.

A 40-year-old man presents with difficulty urinating and yellow eyes since morning, plus calf pain for 2 days after participating in drain-cleaning work. Vitals show icteric sclera and gastrocnemius tenderness. Which supporting examination is recommended?

a)

Dark-field microscopy

b)

Complete urinalysis

c)

Complete blood tests

d)

Blood smear

e)

Fecal occult blood test

38.

Mr. Budi, age 40, has a 1-week fever worsening over the past 2 days. Peripheral blood smear reveals spiral-shaped microorganisms. What is the appropriate therapy?

a)

Doxycycline 2×100 mg

b)

Ciprofloxacin 2×500 mg

c)

Chloramphenicol 4×500 mg

d)

Trimethoprim 2×160 mg

e)

Metronidazole 2×500 mg

39.

A 28-year-old man has fever, yellow eyes, and muscle pain for 1 week; urine is dark; bilateral gastrocnemius tenderness is present. Labs: Hb 11.4 g/dL, leukocytes 15,800 (neutrophils 90%), urea 87 mg/dL, creatinine 3.25 mg/dL, SGOT 125, SGPT 250. Urinalysis: erythrocytes 3+, leukocytes 2+. What is the most appropriate management at this time?

a)

Outpatient care plus doxycycline 2×100 mg for 7 days

b)

Hospitalization plus penicillin G injection 1.5 million units every 8 hours for 5 days

c)

Hospitalization plus azithromycin 1×500 mg for 5 days

d)

Outpatient care plus amoxicillin 3×1000 mg for 7 days

e)

Hospitalization plus amoxicillin 3×1000 mg for 5 days

40.

Mr. Emon, age 35, presents to the ER with a 10-day fever that rises in the evening and defervesces in the morning without reaching normal. Vitals show blood pressure 100/60100/60 mmHg, pulse 56/min, respiratory rate 20/min, temperature 39.7 °C. Exam reveals a coated tongue and tremor. Labs: Hb 12 g/dL, hematocrit 48%, leukocytes 13,300, platelets 170,000. What is the diagnosis?

a)

Dengue hemorrhagic fever

b)

Typhoid fever

c)

Tertian malaria

d)

Meningitis

e)

Leptospirosis

41.

Ms. Ayu, age 20, has had 7 days of fever with nausea, vomiting, constipation, and fatigue. Physical exam shows a coated tongue and abdominal tenderness. Widal titer is 1/3201/320 . Which gold-standard examination helps confirm the diagnosis?

a)

Routine blood tests

b)

Urine culture

c)

Blood culture

d)

Stool culture

e)

Widal test

42.

Ms. Siska, age 24, presents with a fever that remits and exacerbates over a week, now with diarrhea. Physical exam: coated tongue with tremor. When should stool culture ideally be performed?

a)

Week 1

b)

Week 2

c)

Week 3

d)

Week 4

e)

Days 1–3

43.

A 24-year-old woman has had fever for 10 days with epigastric pain and recent constipation. Vitals: 120/80120/80 mmHg, pulse 78/min, respiratory rate 24/min. Widal titer O: 1/3201/320 . What is the most appropriate diet management?

a)

Soft, low fiber, high calorie

b)

Soft, low calorie, low fiber

c)

Soft, low protein, low calorie

d)

Soft, low fat, low calorie

e)

Soft, low carbohydrate, high calorie

44.

Mr. Ghafur, age 35, presents to the ED with a 7-day fever that has not subsided. Vitals: blood pressure 120/80120/80 mmHg, pulse 80/min, body temperature 38 °C. Tubex test is positive 5. What is the appropriate management?

a)

Chloramphenicol 4×500 mg for 7–10 days

b)

Ciprofloxacin 2×500 mg for 7–10 days

c)

Amoxicillin 3×500 mg for 7–10 days

d)

Cefixime 2×100 mg for 7–10 days

e)

Doxycycline 2×100 mg for 7–10 days

45.

A 7-year-old girl has had fluctuating fever for 10 days, worse at night, with nausea, vomiting, occasional abdominal pain, and constipation for 3 days. Exam: blood pressure 100/60100/60 mmHg, pulse 80/min, respiratory rate 24/min, temperature 38.8 °C, hepatomegaly. Widal titers 1/3201/320 and 1/1601/160 . Which antibiotic can be given?

a)

Amoxicillin

b)

Chloramphenicol

c)

Erythromycin

d)

Ciprofloxacin

e)

Metronidazole

46.

Ms. Luna, age 25, 6 weeks pregnant, has had 1 week of fever that rises at night. She also reports constipation and a coated tongue with tremor on protrusion. Laboratory shows Widal O titer 1/3201/320 for Salmonella. What is the most appropriate therapy?

a)

Chloramphenicol

b)

Amoxicillin

c)

Quinolone

d)

Symptomatic treatment only

e)

Cotrimoxazole

47.

A 25-year-old man has a 2-week remittent fever with right upper quadrant pain, nausea, and vomiting, and severe abdominal pain for the past 2 hours. Labs: Widal anti-O 1/3201/320 , anti-H 1/1601/160 , leukocytes 2,500, SGOT/SGPT 66/7766/77 . He continues heavy labor despite illness. Which complication is likely to occur?

a)

Hollow organ perforation

b)

Hepatic perforation

c)

Liver abscess

d)

Fatty liver

e)

Pancreatitis

48.

A patient arrives at the ER with weakness, restlessness, and incoherent speech. He has had 10 days of fever, worse at night; recent nausea, decreased appetite, and constipation for 5 days. Exam: epigastric tenderness, coated tongue, blood pressure 110/70110/70 mmHg, heart rate 89/min, respiratory rate 24/min, temperature 38 °C. Labs: Hb 13 g/dL, leukocytes 12,000, platelets 320,000, Widal 1/6401/640 . What condition is the patient likely experiencing?

a)

Toxic typhoid fever

b)

Severe dehydration

c)

Delirium

d)

Acute psychosis

e)

DHF grade IV

49.

A patient presents with ulcerative lesions in the vulvovaginal area. Laboratory results show anti‑HIV positive, CD4 count < 100100 cells/mm 3^3 , and sputum SPS (+/−). What is the most accurate diagnosis for this patient?

a)

HIV stage I

b)

HIV stage II

c)

HIV stage III

d)

HIV stage IV

e)

HIV stage V

50.

Mr. Roy, 26 years old, has been treated for tuberculosis for 2 years without cure. He is an injection drug user. Vital signs: BP 90/6090/60 mmHg, HR 7676 /min, RR 1616 /min, Temp 38.238.2^{\circ} C. Physical exam finds oral thrush (+). CD4 count is 186186 cells/mm 3^3 . What is the most likely diagnosis?

a)

HIV stage I

b)

HIV stage II

c)

HIV stage III

d)

HIV stage IV

e)

AIDS

51.

A 22‑year‑old woman comes to the health center with fever for 1 month accompanied by cough. She also reports diarrhea that has come and gone for 3 weeks and has not improved with prior treatment. On exam she appears thin, vital signs are within normal limits, and oral candidiasis is present (+). Which supporting test is recommended for this patient?

a)

Western blot

b)

Rapid test

c)

PCR

d)

Immunoassay

e)

CD4 count

52.

A 26‑year‑old woman presents with persistent oral ulcers for about 2 months. She has visited the health center without improvement and notes recent weight loss. She works as a sex worker. Diarrhea (−), chronic cough (−). Vitals: BP 120/70120/70 mmHg, RR 2020 /min, Temp 36.836.8^{\circ} C, Pulse 9494 /min. Laboratory testing shows anti‑HIV reactive by three methods. What further examination should be performed?

a)

Rapid test

b)

CD4 count

c)

Viral load

d)

Immunoassay

e)

C‑reactive protein

53.

A 42‑year‑old man presents to the clinic with white patches in his mouth for the past 2 months and reports dysuria and foul‑smelling urine. He has a history of injection drug use. Physical exam: vital signs within normal limits, generalized lymphadenopathy, and white membranes on the oral mucosa. Laboratory results: CD4 275275 cells/mm 3^3 , HBsAg (+), normal liver function tests. Which antiretroviral regimen is most appropriate?

a)

Zidovudine + Nevirapine + Efavirenz

b)

Tenofovir + Lamivudine + Efavirenz

c)

Zidovudine + Entecavir + Tenofovir

d)

Zidovudine + Emtricitabine + Tenofovir

e)

Tenofovir + Nevirapine + Efavirenz

54.

Mr. Adrian, 35 years old, presents with cough productive of blood for 3 days, fever, weight loss, and recurrent diarrhea for 1 month. Vitals: BP 100/60100/60 mmHg, HR 130130 /min, RR 2828 /min, Temp 37.937.9^{\circ} C; rhonchi over all lung fields. Laboratory: sputum smear for acid‑fast bacilli (BTA) (+) and CD4 350350 cells/mm 3^3 . What is the most appropriate management?

a)

Start ARV after TB treatment is completed

b)

Start ARV together with anti‑TB therapy (OAT)

c)

Alternate ARV and OAT

d)

Start ARV only if OAT is tolerated

e)

Start ARV after a minimum of 2 weeks of OAT

55.

A 30‑year‑old man has had a 1‑month history of cough. He lost 1010 kg in a month, sweats a lot at night, has chronic diarrhea, and oral thrush (+). Whitish lesions are seen on the buccal mucosa and tongue; chest X‑ray shows caseous lesions. CD4 count is 250250 cells/mm 3^3 . What is the appropriate management?

a)

Start ARV and OAT immediately together

b)

Start OAT now; start ARV 1 week later

c)

Start ARV now; start OAT 2 weeks later

d)

Start ARV now; start OAT 4 weeks later

e)

Start OAT now; start ARV 8 weeks later

56.

A 25‑year‑old woman is brought to the ER for sudden seizures. Three days earlier she complained of headache. She was diagnosed HIV positive 2 months ago. CT scan of the head reveals a round lesion with ring enhancement and edema in the basal ganglia. Which opportunistic infection is most likely?

a)

Cerebral toxoplasmosis

b)

Cysticercosis cellulosae

c)

Amoebic brain abscess

d)

Cerebral malaria

e)

TB meningitis

57.

A 25‑year‑old woman presents with foul‑smelling watery diarrhea mixed with mucus and blood for 1 day. She often eats street food. Vitals: BP 100/70100/70 mmHg, HR 8888 /min, RR 2020 /min, Temp 37.837.8^{\circ} C; bowel sounds increased (+). Stool exam shows rounded masses with two nuclei that contain ingested erythrocytes (+). What is the most accurate diagnosis?

a)

Bacillary dysentery

b)

Shigellosis

c)

Balantidiasis

d)

Cholera

e)

Amoebiasis

58.

An 18‑year‑old man presents with 2 days of diarrhea, more than 10 times in one day, accompanied by mucus and blood with a fishy odor. He feels weak. Vitals: BP 100/70100/70 mmHg, HR 8888 /min, RR 2020 /min, Temp 37.837.8^{\circ} C; bowel sounds increased (+). Stool microscopy shows numerous short, red, rod‑shaped bacteria consistent with Shigella species. What is the most accurate diagnosis?

a)

Amoebic dysentery

b)

Shigellosis

c)

Balantidiasis

d)

Cholera

e)

Amoebiasis

59.

A 35‑year‑old man presents to the health center with diarrhea mixed with blood and mucus, occurring 5 times per day, accompanied by nausea and vomiting for 2 days and abdominal pain. Vitals: BP 120/80120/80 mmHg, HR 9090 /min, RR 2424 /min, Temp 3939^{\circ} C; no signs of dehydration. What is the most appropriate initial supporting examination?

a)

Stool culture

b)

Colonoscopy

c)

Complete blood count

d)

Complete stool examination

60.

A 7‑year‑old girl presents with mucus‑ and blood‑streaked diarrhea for 5 days, plus nausea and abdominal pain. She often eats raw vegetables. Vitals: Pulse 9090 /min, RR 2626 /min, Temp 37.437.4^{\circ} C; no dehydration. Macroscopic stool exam shows erythrocytes (+), leukocytes (+), small round microorganisms containing erythrocytes, and Charcot–Leyden crystals (+). What is the diagnosis?

a)

Amoebic dysentery due to Escherichia coli

b)

Bacillary dysentery due to Shigella dysenteriae

c)

Dysentery form due to ulcerative colitis

d)

Amoebic dysentery due to Entamoeba histolytica

e)

Bacillary diarrhea due to Salmonella typhi

61.

A 25‑year‑old woman presents with foul‑smelling watery diarrhea mixed with mucus and blood for 1 day. She often eats street food. Vitals: BP 100/70100/70 mmHg, HR 8888 /min, RR 2020 /min, Temp 37.837.8^{\circ} C; bowel sounds increased (+). Stool microscopy shows a large round ciliated protozoan cyst with distinct nuclei. What is the most appropriate therapy?

a)

Ciprofloxacin 2×5002\times500 mg

b)

Cotrimoxazole 2×4802\times480 mg

c)

Tetracycline 4×5004\times500 mg

d)

Metronidazole 3×5003\times500 mg

e)

Cotrimoxazole 2×9602\times960 mg

62.

A 20‑year‑old man presents with 15 episodes of diarrhea in one day, with mucus and blood. He appears weak with dry lips and moderate dehydration. Vitals: BP 100/80100/80 mmHg, HR 110110 /min, RR 2020 /min, low‑grade fever. CBC shows leukocytosis. Stool microscopy reveals numerous red, rod‑shaped bacteria compatible with Shigella species. Besides rehydration, what is the appropriate management?

a)

Attapulgite plus cotrimoxazole 2×4802\times480 mg

b)

Attapulgite plus tetracycline 4×5004\times500 mg

c)

Loperamide plus ciprofloxacin 2×5002\times500 mg

d)

Attapulgite plus ciprofloxacin 2×5002\times500 mg

e)

Loperamide plus cotrimoxazole 2×4802\times480 mg

63.

Mr. Wahyu, 34 years old, presents with bloody stools containing mucus, occurring 3–4 times daily for 4 days, with tenesmus and abdominal pain during defecation. Vitals are within normal limits; stool exam is positive for mucus and blood. What complication most commonly occurs in this condition?

a)

Perforation

b)

Peritonitis

c)

Liver abscess

d)

Amoeboid formation

e)

Megacolon

64.

A 15‑year‑old boy presents with watery stools sometimes mixed with mucus and blood for 5 days. Vitals are normal. Stool microscopy shows a trophozoite with ingested erythrocytes and a single nucleus consistent with Entamoeba histolytica. What is the most likely cause of his illness?

a)

Entamoeba histolytica

b)

Balantidium coli

c)

Taenia saginata

d)

Treponema pallidum

e)

Vibrio cholerae

65.

A 30‑year‑old woman is brought to the health center with watery diarrhea for 3 days accompanied by abdominal pain and nausea. Physical exam: generally well, alert, normal skin turgor, Temp 37.637.6^{\circ} C; abdominal exam: increased peristalsis. Microscopic stool exam shows a round microorganism with two nuclei (a macronucleus and a micronucleus). Which drug is most appropriate?

a)

Mebendazole

b)

Metronidazole

66.

A 7-year-old boy is brought to the ER with diarrhea 6 times in one day, abdominal bloating, and frequent flatulence. Vital signs are normal, and there are no signs of dehydration. Macroscopic stool is foul-smelling, greasy, and mucoid. Microscopy shows cysts with 4 nuclei and an axostyle, as in the referenced image. What is the diagnosis?

a)

Giardiasis

b)

Shigellosis

c)

Balantidiasis

d)

Cholera

e)

Amoebiasis

67.

An 18-year-old woman presents with one week of diarrhea. Stools appear oily and have a fishy odor. She reports abdominal discomfort. On examination she appears weak; vital signs: T 37.5°C, BP 90/60 mmHg, HR 100/min, RR 20/min. Stool microscopy shows flagellated protozoa compatible with the referenced image. Which therapy is most appropriate?

a)

Tetracycline 500 mg three times daily for 7 days

b)

Albendazole 400 mg single dose

c)

Metronidazole 500 mg three times daily for 7 days

d)

Pyrantel pamoate 10 mg/kg body weight for 3 days

e)

Metronidazole 250 mg three times daily for 7 days

68.

A 41-year-old man has watery diarrhea for 2 days and appears very weak. He reports >15 bowel movements per day. There is no mucus or blood. Stools are whitish like rice-washing water. Vital signs: BP 100/60 mmHg, HR 80/min, RR 20/min, T 37.5°C; skin turgor is markedly decreased. Which antibiotic management is most appropriate?

a)

Metronidazole 3×500 mg

b)

Tetracycline 4×500 mg

c)

Ciprofloxacin 2×500 mg

d)

Erythromycin 4×500 mg

e)

Chloramphenicol 3×500 mg

69.

A 30-year-old woman reports 30 episodes of watery bowel movements in the last 8 hours. Stools are rice-water in appearance, fishy-smelling, mucoid, but without blood. She has 10 episodes of vomiting. Examination shows signs of dehydration: BP 80/60 mmHg, HR 120/min, RR 22/min, T 37.5°C, decreased skin turgor, sunken eyes, and dry oral mucosa. Stool microscopy shows leukocytes 11–15/HPF, erythrocytes negative, amoeba negative. What is the most appropriate therapy?

a)

Amoxicillin 500 mg three times daily

b)

Ampicillin 500 mg three times daily

c)

Thiamphenicol 500 mg four times daily

d)

Doxycycline 300 mg single dose

e)

Metronidazole 500 mg three times daily

70.

A 25-year-old woman recently returned from Sulawesi presents with lower abdominal pain and painful urination with reddish urine. She works at a fish farm and frequently enters river water. Vital signs: BP 100/60 mmHg, HR 80/min, RR 20/min, T 37.5°C. Routine stool examination reveals the egg shown in the referenced image. What is the most likely causative organism?

a)

Schistosoma japonicum

b)

Schistosoma haematobium

c)

Schistosoma mansoni

d)

Paragonimus westermani

e)

Fasciolopsis buski

71.

A 12-year-old girl has abdominal pain and diarrhea for one week. She also reports painful urination with reddish urine, poor appetite, and weight loss. Conjunctivae are anemic; temperature 38.5°C. Two weeks ago she vacationed in Central Sulawesi and played in rice fields. Stool examination shows the eggs depicted in the referenced image. What therapy should be given?

a)

Albendazole 400 mg daily for 3 days

b)

Pyrantel pamoate 10 mg/kg body weight

c)

Mebendazole 100 mg three times daily for 3 days

d)

Praziquantel 10 mg/kg body weight per day

e)

Diethylcarbamazine (DEC) 6 mg/kg/day for 12 days

72.

A 7-year-old child presents with 3 days of abdominal pain, nausea without vomiting, loss of appetite, weakness, and occasional diarrhea. Recently there has been weight loss and itching around the anus. Family often consumes pork. Vital signs are normal. Microscopy shows the referenced image. What is the diagnosis?

a)

Schistosomiasis

b)

Ascariasis

c)

Taeniasis

d)

Trichuriasis

e)

Enterobiasis

73.

A 16-year-old boy reports passing white–yellow, motile worm fragments with stool that move when placed on the floor. Fragment size is 0.25–0.5 cm. Stool microscopy shows a proglottid with a uterus having 16 lateral branches and the eggs in the referenced image. Which organism is the cause?

a)

Taenia saginata

b)

Ascaris lumbricoides

c)

Taenia solium

d)

Cysticercosis

e)

Ancylostoma duodenale

74.

A 7-year-old girl is brought with 3 days of abdominal pain, nausea without vomiting, loss of appetite, weakness, and occasional diarrhea. Recently there has been weight loss. The family often eats pork. Vital signs are normal. Stool microscopy shows proglottids. Which therapy should be given?

a)

Albendazole

b)

Praziquantel

c)

Pyrantel pamoate

d)

Mebendazole

e)

Omeprazole

75.

A 35-year-old man presents with 6 days of fever and 2 days of shortness of breath. He has cough with sputum tinged with blood. He reports previously expelling a worm approximately 12 cm long. Laboratory studies show hypereosinophilia. What is the most likely diagnosis?

a)

Schistosomiasis

b)

Ascariasis

c)

Taeniasis

d)

Trichuriasis

e)

Enterobiasis

76.

A 6-year-old boy appears lethargic with decreased appetite and nausea. He has lost 2 kg. Vital signs are normal. Stool examination shows the egg in the referenced image. Which parasite species matches these egg characteristics?

a)

Strongyloides stercoralis

b)

Taenia saginata

c)

Ascaris lumbricoides

d)

Enterobius vermicularis

e)

Paragonimus westermani

77.

A 7-year-old boy is evaluated for abdominal bloating and occasional nausea/vomiting. His mother reports that a worm about 10 cm was expelled during defecation. Vital signs are normal; nutritional status is suboptimal. Stool examination shows eggs with a thick shell and an outer albuminous coat. What is the transmission method of this parasite?

a)

Ingesting infective larvae

b)

Ingesting the parasite’s eggs

c)

Eggs penetrating the skin

d)

Rhabditiform larvae penetrating the skin

e)

Filariform larvae penetrating the skin

78.

A 7-year-old boy has one week of abdominal pain accompanied by nausea and vomiting. He also has watery diarrhea 3–4 times per day without mucus. One month ago, a worm was expelled during defecation. Physical examination: T 36.5°C, BP 100/65 mmHg, HR 90/min, RR 25/min; conjunctivae anemic; tenderness in the mid-abdomen. Stool smear reveals oval eggs with a thick three-layered shell. What is the most appropriate management?

a)

Albendazole 400 mg single dose

b)

Albendazole 400 mg three times daily

c)

Praziquantel 10 mg/kg body weight single dose

d)

Metronidazole 3×500 mg

e)

Amoxicillin 3×500 mg

79.

A stool examination found oval eggs with transparent walls. What is the diagnosis in the case described?

a)

Schistosomiasis

b)

Ascariasis

c)

Taeniasis

d)

Trichuriasis

e)

Hookworm infection

80.

A 6-year-old boy is brought to the ER with weakness and decreased appetite. He is a primary school student and has recently had difficulty concentrating. He often plays in the garden without wearing sandals. Laboratory: Hb 5.65.6 g/dL. Stool examination shows thin-walled, transparent eggs. What is the etiologic agent in this case?

a)

Trichuris trichiura

b)

Necator americanus

c)

Ancylostoma braziliense

d)

Ascaris lumbricoides

e)

Strongyloides stercoralis

81.

A 10-year-old boy is brought to the clinic with fatigue, pallor, and easy tiredness. He often plays outdoors without footwear. Physical exam shows anemia and ground itch on the feet as in the image. What is the correct etiology?

a)

Ascaris lumbricoides

b)

Ancylostoma duodenale

c)

Ancylostoma caninum

d)

Schistosoma haematobium

e)

Enterobius vermicularis

82.

A 25-year-old man has felt increasingly weak for the past month, with nausea and vomiting. Vitals: BP 120/80120/80 mmHg, HR 8888 /min, RR 2424 /min, Temp 36.536.5^\circ C. Conjunctivae are anemic. Stool examination shows the eggs pictured. What is the transmission method of this parasite?

a)

Ingesting the eggs

b)

Rhabditiform larvae penetrate the skin

c)

Filariform larvae penetrate the skin

d)

Cercaria penetrate the skin

e)

Microfilariae enter blood via mosquito bite

83.

A 9-year-old boy presents with nocturnal perianal itch. Vitals normal, weight 2323 kg. There is perianal irritation from scratching. Graham’s Scotch tape test shows asymmetric eggs with one flattened side as in the image. What is the most likely etiology?

a)

Trichuris trichiura

b)

Ascaris lumbricoides

c)

Ancylostoma duodenale

d)

Strongyloides stercoralis

e)

Enterobius vermicularis

84.

A 6-year-old boy presents with itching and redness in the perianal area for 3 days. He lives in a crowded household where many have similar complaints. What finding on examination supports the diagnosis?

a)

Eggs on stool examination

b)

Filariform larvae on stool examination

c)

Gravid proglottids on stool examination

d)

Eggs on an anal swab

e)

Rhabditiform larvae on stool examination

85.

A 10-year-old boy has watery bloody stools for 1 month. His mother noticed a meat-like mass protruding from the anus for the past 3 days. The child often plays in soil and rarely washes hands before eating. Vitals: BP 100/60100/60 mmHg, HR 9090 /min, RR 2424 /min, Temp 36.536.5^\circ C. Abdomen is tender. Stool examination shows the egg pictured. What is the etiology in this case?

a)

Enterobius vermicularis

b)

Ancylostoma duodenale

c)

Trichuris trichiura

d)

Ascaris lumbricoides

e)

Intestinal amoebiasis

86.

A 35-year-old man presents with diarrhea and anemia. Exam shows pale conjunctiva; vitals are within normal limits. Stool examination reveals jar-shaped (barrel-shaped) eggs. What is the appropriate therapy for this patient?

a)

Albendazole 400400 mg once daily for 77 days

b)

Praziquantel 500500 mg once daily for 77 days

c)

Pyrantel pamoate 500500 mg twice daily for 22 days

d)

Mebendazole 100100 mg twice daily for 33 days

e)

Diethylcarbamazine 100100 mg weekly for 4040 weeks

87.

A 40-year-old man presents to the ER with bloody diarrhea for 2 days, abdominal pain, nausea, and vomiting. He often eats without washing his hands beforehand. Stool examination shows eggs like a jar (barrel-shaped). What complication is most likely from this parasite?

a)

Hepatic abscess

b)

Perforated peritonitis

c)

Rectal prolapse

d)

Obstructive ileus

e)

Paralytic ileus

88.

A 13-year-old boy presents with abdominal pain, watery stools, and perianal itching. Earlier he had a transient red raised lesion on the foot that resolved in 22 days. Stool examination reveals slender, long larvae without sheath; the posterior end is bifid like the letter W. Which species causes these complaints?

a)

Ascaris lumbricoides

b)

Ancylostoma duodenale

c)

Strongyloides stercoralis

d)

Ancylostoma braziliensis

e)

Necator americanus

89.

A 35-year-old farmer from Irian Jaya presents with swelling of the right upper leg for 5 days, fever, and tender nodes in the groin and axilla; there is pitting edema of the left leg. Labs: Hb 1313 g/dL, leukocytes 6,5006{,}500 /µL, ESR 2525 mm/hour. Peripheral blood smear shows the image. What is the most likely diagnosis?

a)

Chyluria

b)

Lymphangitis

c)

Filariasis

d)

Knobs

e)

Inguinal hernia

90.

A 48-year-old man has progressive swelling of the right leg for 3 months, preceded by recurrent fever and swelling that subsided. Peripheral blood smear shows a parasite with stacked nuclei and a cephalic space with a length-to-width ratio of 2:12{:}1 . What is the most appropriate etiology?

a)

Loa-loa

b)

Dirofilaria

c)

Brugia malayi

d)

Brugia timori

e)

Wuchereria bancrofti

91.

A 30-year-old man presents with 3 days of fever, edema of the left lower limb, and swelling in the left groin. Night-time peripheral blood smear with Giemsa shows microfilariae with a sheath, orderly nuclei, and nuclei that do not reach the tail tip. Which species of microfilaria is present?

a)

Wuchereria bancrofti

b)

Brugia malayi

c)

Brugia timori

d)

Loa-loa

e)

Wuchereria bancrofti and Brugia malayi

92.

A 32-year-old man has scrotal and left leg swelling, and urine that is milky like milk. Several neighbors have similar disease. What is the most appropriate supporting examination for diagnosis in this patient?

a)

Blood culture

b)

Culture of lymph fluid

c)

Doppler ultrasonography

d)

Night-time peripheral blood smear

e)

Day-time peripheral blood smear

93.

A child presents with swelling of the feet and scrotum. Several neighbors have the same disease. For thick blood smear examination, when should the peripheral blood specimen be collected?

a)

Night 20:0020{:}0022:0022{:}00

b)

Night 22:0022{:}0002:0002{:}00

c)

Morning 08:0008{:}0010:0010{:}00

d)

Morning 10:0010{:}0012:0012{:}00

e)

Noon 12:0012{:}0014:0014{:}00

94.

A 12-year-old girl has progressive swelling of the right leg for 2 weeks. Neighbors have similar complaints. Local exam shows inguinal lymphadenopathy, non-pitting edema, and peeling skin. What is the appropriate therapy?

a)

Diethylcarbamazine (DEC) 66 mg/kg/day in divided doses for 1212 days

b)

Ivermectin single dose 200200 µg/kg

c)

Praziquantel 4040 mg/kg divided in 33 doses for 11 day

d)

Albendazole 400400 mg once weekly for 44 weeks

e)

No antiparasitic therapy; compression stockings only