Font size
WorksheetsImmune System Review Game
Total questions: 100
Worksheet time: 50mins
__________ are phagocytes that circulate in the blood.
B cells
macrophages
Plasma cells
T cells
Monocytes
__________ are helper and inducer cells.
B cells
Macrophages
Plasma cells
T cells
Monocytes
_________ are the source of antibody-producing cells.
B cells
Macrophages
Plasma cells
T cells
Monocytes
_________ are macrophage precursor cells.
B cells
Macrophages
Plasma cells
T cells
Monocytes
_________ produce specific antibodies.
B Cells
Macrophages
Plasma Cells
T Cells
Monocytes
The surface of most vertebrate cells possesses self-markers called major __________.
histocompatibility complex proteins
T-cell receptors
antigens
immunoglobulins
The surface defenses of the body consist of the ______ and the mucous membranes lining the digestive and respiratory tracts.
bone marrow
skin
T-cells
lymphocytes
__________ diseases are those abnormal conditions in which the body's defensive cells fail to make the self versus the non-self distinction correctly, and attack the body's own tissues.
Septic
Non Discrete
Autoimmune
Cancerous
The cellular defenses of vertebrates are complemented by a very effective chemical defense called the _________ system.
autoimmune
relational
lymphatic
complement
Virus-infected cells secrete a class of proteins called ________ that play a key role in body defense.
interferon
cytokines
antigens
interleukin-4
_________ are molecules released by activated helper T cells.
Antigens
Immunoglobulins
Cytokines
Antibodies
Lymphocyte receptors are encoded by genes that are assembled by _______ rearrangement and mutation.
histochemical
reversible
gametic
DNA
Because of natural _______, a mature animal's immune system does not attack its own tissues.
immunological tolerance
homeostasis
histochemicals
differentiation
The human immunodeficiency virus mounts a direct attack on TH cells by recognizing the _______ surface proteins associated with these cells.
Fc
CD4
epitope
cytokine
The large, irregularly shaped cells that kill bacteria by digesting them are called
monocytes
erythrocytes
macrophages
bacteriophages
antibodies
The procedure of injecting a harmless microbe in order to confer resistance to a dangerous one is called
vaccination
immunity
antibody modification
interferon activation
immunoglobulin synthesis
Nonself molecules called antigens cause the vertebrate system to produce proteins known as
interferons
antibodies
complements
immunoglobulins
phagocytes
The molecule that provokes a specific immune response is
antigen
lymphocyte
antibody
lysozyme
Which is not one of the blood types?
A
B
AB
O
BB
HIV mounts a direct attack on ___ cells
TH Cells
TC Cells
HT Cells
TB Cells
_____ cause tissue rejection
B-cells
T-cells
MHC
all of the above
_____ regulates other immune cells or attacks cells that carry specific antigens
B cells
A cells
T cells
Macrophages
MAC’s are made of_____.
T cells
macrophages
proteins
B cells
Innate immunity is ______
response to invading pathogens that involves both soluble factors and different types of blood cells.
potential routes of entry
both answers are correct
______ gives rise to the cells of the immune system.
mast cells
lymphocytes
Hematopoiesis
T cells
The secondary response to an antigen is ____ effective than the primary response.
more
less
the same
Allergies are caused by _____ secretion in response to antigens
IgE
lympocytes
T cells
B cells
______ eliminates virally infected cells and tumor cells
B cells
Cytotoxic T Cells
Proteins
Macrophages
Which of the following is not a characteristic of the adaptive immune system?
Specificity of recognition of an antigen
Ability to distinguish self- antigens from nonself
Wide diversity of antigens that can be specifically recognized
All of these are characteristics
What type of bond holds together the four chains of an immunoglobulin molecule?
Hydrogen Bond
Hydrocarbon bond
Disulfide bond
Water-based bond
How many alleles does the Major Histocompatibility Complex (MHC) have?
2
64
2000
200
The plus or minus symbol shown in a blood type represents
the presence or absence of ‘A’ surface proteins
The presence or absence of ‘B’ surface proteins
The presence or absence of the Rh factor
None of the above
Immunoglobulin molecules are also known as what?
Macrophages
Antibodies
B cells
Mast cells
Which of the following is a function of B cells?
Helps stop immune response after antigen is eliminated.
Attacks cells that carry specific antigens
Consumes cell debris via phagocytosis
Responds to antigens by secreting antibodies
When B cells produce antibodies, the process as known as what?
Autoimmunity
Adaptive immunity
Humoral immunity
None of these
Where do T cells mature?
bone marrow
Within blood plasma
Thymus
T cells do not mature.
What is one way in which skin does not prevent the entrance of antigens?
Having a pH of 3-5
Normal flora outnumbering pathogenic bacteria
Provides a strong barrier
These are all ways in which skin prevents the entrance of antigens.
Immunoglobulins come in five classes: IgM, IgD, IgG, IgA, and IgE. When an antigen is present, which of the classes can lead to an allergic response?
IgA class
IgE class
IgD class
IgM class
Jenner discovered that people previously infected with cowpox did not become infected by smallpox because ________.
he cowpox destroyed any smallpox introduced.
The smallpox always mutated into a non harmful state when in the presence of cowpox.
The smallpox had extremely similar surface proteins to the cowpox, meaning a quick immune response was produced to destroy the smallpox before symptoms could appear.
None of the above
The reason why the influenza vaccine is not permanent is due to the fact that:
The vaccine only lasts for the course of one year before no longer reacting to the flu virus.
The flu virus will alter its surface proteins to avoid recognition by the immune system.
Both of these are correct
None of these
Immunoglobulin diversity is generated through what?
Genetic recombination
Hematopoiesis
DNA rearrangement
None of theses
Interleukin-1 is an example of what?
An antibody
Mast cell
Macrophage
Cytokine
Where does b-cell maturation occur?lymph nodes
lymph nodes
thymus
bone marrow
spleen
What is the central dogma theory?
DNA-RNA-Protein
Protein-RNA-DNA
RNA-DNA-Protein
RNA-Protein-Antigen
What is the largest organ in the human body?
spleen
colon
liver
skin
What is the most abundant circulating leukocyte, that also use phagocytosis?
macrophages
NKC
neutrophils
phagocytes
What is the meaning of macrophages?
big eater
little eater
of bacteria
matured cells
Who made the vaccine for smallpox?
Mendell
Darwin
Salk
Jenner
Who made the vaccine for Polio?
Salk
Darwin
Mendell
Jenner
What is true of natural killer cells?
Do not attack invading cells directly
Use phagocytosis
Monocytes mature into macrophage
Kill microorganisms through phagocytosis
What is the definition of inflammation?
Genetic rearrangements that generate a diverse set of molecules to recognize any invader
The process by which the body's white blood cells and substances they produce protect us from infection with foreign organisms, such as bacteria and viruses.
Proteins aggregate to form a membrane attack complex on surface of pathogen
perforations to form in the pathogen
What does a fever do?
slow reproduction rate of microorganisms
promotes activity of phagocytic cells
make the spleen and liver store iron which slows bacterial replication
all of these
What is an antigen?
molecule that provokes a specific immune response
a molecule that fights cancer
a molecule that makes it easier to get a disease
a molecule that makes you get a fever
What do mast cells do?
make testosterone
secrete histamine
make antigens
make estrogen
In immunoglobulin cells what are the 2 longer polypeptide chains called
light chains
medium chains
heavy chains
small chains
In immunoglobulin cells what are the 2 short polypeptide chains?
light chains
heavy chains
small chains
medium chains
What is immunological tolerance
rejection of self cells
acceptance of self cells
acceptance of non self cells
rejection of non self cells
True or false ⅔ of people with autoimmune diseases are women?
True
False
What is delayed type hypersensitivity?
when you get symptoms immediately
when you get symptoms that are mild
when you get symptoms 24-48 hours later
when you don't get symptoms
What is immediate hypersensitivity?
when you get symptoms immediately
when you get mild symptoms
when you get symptoms 24-48 hours later
when you don't get symptoms
What is the rh factor in blood typing?
amount of blood platelets
white blood cell count
clotting ability
the rhesus factor, additional small surface proteins that you have (+) or don't (-)
What is the most common type of allergy?
Immediate hyposensitivity
Immediate hypersensitivity
Delayed type sensitivity
Allergen
Pollen
Immunoglobulins consist of 4 polypeptide chains, what chains would respond or interact with an antigen?
2 light
2 heavy
both
neith
T(c) cells are:
Cytotoxic T cells
Cytopathic T cells
Cytotropic T cells
Cytokines T cells
What does MALT stand for?
Muscle-associated lymphoid tissue
Muscosal-associated lysis tissue
Molecule-associated lymphoid trouble
Mammary-associated lymphoid tissue
Mucosal-associated lymphoid tissue
Where is MALT found?
Lymph nodes
Spleen
Stomach
Both spleen and stomach
Both lymph nodes and spleen
Monoclonal antibodies exhibit specificity for ____ epitope(s).
One
Two
Three
Four
Your friend got in an accident and cut themselves severely. They will need a blood transfusion and their blood type is AB positive. What blood type will your friend be able to receive?
Type A pos.
Type B neg.
Type O pos.
All types
None
What organism can you get salmonella from?
goat
Cow
Chicken
Sheep
Duck
What was invented as a treatment for tuberculosis in the middle of the 20th century?
Bacteria
Antibiotics
Viruses
Drugs
Nothing
What cells in the body does the HIV-human immunodeficiency viruses target?
Cytotoxic T cells
CD4+ Helper T cells
All cells
Nice
Which group/s of organism do we know as being potential pathogens?
Protists
Bacteria
Fungi
Virus
All of these are potentially pathogenic
Why do we need NSAIDs?
To get rid of allergies
To alleviate inflammation and fever
To increase autoimmune diseases
To become resistant to everything
We don't need NSAIDs
When macrophages are in their immature phase they are called _______.
Phagocytes
Microcytes
Monocytes
Neutrophils
Cytotoxins
What is false about skin?
Largest organ of the body
Low pH level
Can be reinforced with chemical weapons
Provides a niche for harmless or beneficial bacteria
None of these
A PAMP is a
molecular pattern.
leukocyte
bacterium
tissue
An incubation period is
the time it takes for a disease to become infectious.
the time in which the symptoms of a disease are observable.
the time between the exposure and the onset of a disease.
the period in which the disease is transmittable.
_____ is a sign of an inflammatory response.
Redness
Swelling
Pain
Warmth
All of these are correct
Natural Killer Cells destroy infected cells causing ______.
apoptosis.
phagocytosis
producing antibodies.
triggering other responses.
The possible genotypes of person who exhibits the A+ blood phenotype are
A+ A-, A+ O+, A+ A+, A+ O-, A- O+
A- A-, A+ O-, A+ A-
A+ O+, A- B+, A+ A+, A+ O-
A+ A-, A+ B-, A- O+
_____ occurs when a blood type is rejected and attacked by the immune system.
Coagulation
Agglutination
Inflammatory Response
Phagocytosis
There are about ______ different proteins in the complement system.
40
20
30
15
Adaptive immunity is characterized by
specificity of antigens.
memory
distinguishing antigens.
all of these are correct
Erythroblastosis Fetalis is when
a mother's blood is incompatible with the baby’s.
a fetus does not develop beyond a handful of cells.
a baby is born prematurely.
a mother’s antigens see the baby itself as an invader.
_____ was the first virus used to inoculate against another virus.
Influenza
HIV
Tuberculosis
Cowpox
B cells produce _____ antibodies a minute.
500
2000
5000
1500
____ & ____ use phagocytosis to eliminate invaders.
Neutrophils, Macrophages
NKCs, Macrophages
NKCs, Neutrophils
PAMP, Macrophage
What enzyme is released when Natural Killer Cells find a cell with damaged surface proteins?
Perforin
Intererleukin-1
Lysis
Histamine
The _____________ is a nonspecific response to infection or tissue injury.
bleeding
inflammatory response
breathing
allergic
What is the MALT?
A system that includes the tonsils, the appendix, and a large number of follicles located in the connective tissue under mucosal surfaces.
mucosa-associated lymphoid tissue
All of these are correct
None of the Above
The _____ response to an antigen is more effective than the ______ response.
tenth, seventh
third, fourth
primary, secondary
secondary, primary
Who discovered ABO blood typing?
Jenner
Mullins
Kary
Landsteiner
HIV infection kills ___ cells and causes immunosuppression
Cytotoxic
memory
helper T
plasma
Which blood type is the universal donor
AB+
AB-
O+
O-
Complement proteins can perform all of the functions except
amplify inflammatory response.
attract phagocytes to the site of infection.
coat invading microbes.
insert themselves into the foreign cell's plasma membrane.
activate interferons.
Histamine and prostaglandins are called
immunoglobulins
antibodies
inflammatory agents.
allergic agents.
pyrogens
Which of the following is not part of the inflammatory response?
Histamine and other chemicals are released, which produce redness, warmth, and edema.
Neutrophils, monocytes, and macrophages attack the invading microbes and contribute to the pus.
Antibodies and interferons are produced against the antigens
Invading agent causes the release of pyrogens, which produce a fever.
Immunity gained by the transfer of antibodies across the placental barrier (mother to unborn child) is called
passive immunity.
acquired immunity.
humoral immunity.
cell-mediated immunity.
autoimmunity.
Some viral pathogens evade detection by the vertebrate immune system by a mechanism that involves
becoming a symbiont.
becoming nonvirulent.
frequent changing of surface antigens.
becoming metabolically inactive.
becoming a spore.
Antigen shifting allows the pathogens to escape from immune recognition. This mechanism is employed by all of the following except
flu viruses.
trypanosomes
malarial protozoans.
HIV
Antigenic shifting occurs in all of the answers given in this question.
