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Unit 1: Chemistry of Life

Total questions: 82

Worksheet time: 44mins

Name
Class
Date
1.

Which of the following does not result from hydrogen bonding in water molecules?

a)

Cohesion

b)

Adhesion

c)

Surface Tension

d)

Dissolving fats

2.

Why is water considered polar?

a)

Nonpolar covalent bonds in structure

b)

Ionic bonds in structure

c)

Polar covalent bonds in structure

d)

Hydrophobic interaction in structure

3.

Which macromolecule(s) have nitrogen?

a)

Carbohydrates

b)

Proteins

c)

Nucleic Acids

d)

Nucleic Acids & Proteins

4.

Which macromolecule(s) have phosphorus?

a)

Carbohydrates

b)

Proteins

c)

Nucleic Acids

d)

Fats

5.

Which macromolecule(s) have sulfur?

a)

Carbohydrates

b)

Proteins

c)

Nucleic Acids

d)

Fats

6.

Describes the forming of a bond between monomers with the removal of a water molecule.

a)

Hydrolysis

b)

Dehydration

7.

Describes the breaking of a bond within a polymer using water.

a)

Hydrolysis

b)

Dehydration

8.

Which of the following is NOT in the monomer of a nucleic acid?

a)

pentose sugar

b)

nitrogenous base

c)

phosphate

d)

amino acid

9.

Which of the following is NOT in the monomer of a protein?

a)

Amine Group

b)

R Group

c)

Carboxyl Group

d)

Nitrogenous Base

10.

Describe the orientation of the phospholipids in the membrane.

a)

Phospholipids orient in bilayer with hydrophilic heads on exterior

b)

Phospholipids orient in monolayer with hydrophilic head on extracellular

c)

Phospholipids orient in bilayer with hydrophobic tails on exterior

d)

Phospholipids orient in monolayer with hydrophobic tails on extracellular

11.

How is DNA/RNA synthesis directionally oriented?

a)

new nucleotides are added to 5' phosphate

b)

new nucleotides are added to 3' phosphate

c)

new nucleotides are added to 5' hydroxyl

d)

new nucleotides are added to 3' hydroxyl

12.

Identify the pairing and number of bonds in DNA double helix

a)

A pairs with T (2 bonds) & G pairs with C (3 bonds)

b)

A pairs with G (2 bonds) & T pairs with C (3 bonds)

c)

A pairs with T (3 bonds) & G pairs with C (2 bonds)

d)

A pairs with G (3 bonds) & T pairs with C (2 bonds)

13.

How is DNA/RNA synthesis directionally oriented?

a)

new nucleotides are added to 5' phosphate

b)

new nucleotides are added to 3' phosphate

c)

new nucleotides are added to 5' hydroxyl

d)

new nucleotides are added to 3' hydroxyl

14.

What component of the polypeptide is the next amino acid added forming the peptide bond?

a)

amino group

b)

hydrogen

c)

carboxyl group

d)

R groups

15.

Which protein involves R group bonding to form the final three dimensional structure?

a)

primary

b)

secondary

c)

tertiary

d)

quaternary

16.

Which protein structure involves the peptide bonds between amino acids?

a)

primary

b)

secondary

c)

tertiary

d)

quaternary

17.

DNA and RNA differ on many qualities, which of the following is NOT a difference?

a)

Sugar

b)

Nitrogenous Base

c)

Phosphate Group

d)

Strandedness

18.
Organic chemistry is a science based on the study of
a)
functional groups.
b)
vital forces interacting with matter.
c)
carbon compounds.
d)
inorganic compounds.
19.
Which of the following best summarizes the relationship between dehydration reactions and hydrolysis?
a)
Hydrolysis only occurs in the urinary system, and dehydration reactions only occur in the digestive tract.
b)
Hydrolysis creates monomers, and dehydration reactions break down polymers.
c)
Dehydration reactions can occur only after hydrolysis.
d)
Dehydration reactions assemble polymers, and hydrolysis breaks down polymers.
20.
This is a picture of a?
a)
Amino Acid
b)
Nucleic Acid
c)
Lipid
d)
Polysaccharide
21.
What is this molecule? (hint: Count the C:H:O)
a)
disaccharide
b)
monosaccharide
c)
polysaccharide
d)
starch
22.
What are the monomers of carbohydrates?
a)
Nucleotides
b)
Amino Acids
c)
Fatty Acids
d)
Monosaccharides
23.
What macromolecule makes up the cell membrane's lining?
a)
Saturated Fatty acid chains
b)
Phospholipids
c)
Polypeptide chains
d)
Cellulose polysaccharide Chains
24.
What element is found in proteins and nucleic acids but not carbs nor lipids?
a)
carbon
b)
hydrogen
c)
nitrogen
d)
oxygen
25.
 What molecule is this?
a)
steroid
b)
polysaccharide
c)
phospholipid
d)
triglyceride
26.
How does your body use lipids?
a)
Primary source of energy
b)
energy storage and insulation
c)
speeds up chemical reaction
d)
defense
27.
Which of the 4 major macromolecules provides a quick burst of energy?
a)
Carbohydrates
b)
Lipids
c)
Proteins
d)
Nucleic Acids
28.
Alpha helix and beta pleated sheets are part of what level of protein structure?
a)
primary
b)
secondary
c)
tertiary
d)
quaternary
29.
The fact that ice floats on liquid water is due to the fact that water's solid is ___________ than it's liquid form
a)
less polar
b)
more polar
c)
less dense
d)
more dense
30.
The property of water that allows water molecules to stick to another substance is
a)
adhesion
b)
cohesion
c)
density
d)
specific heat
31.
The property of water that allows water molecules to stick to each other is
a)
adhesion
b)
cohesion
c)
density
d)
specific heat
32.
Which of the following is correctly defined as the attraction of the hydrogen from one molecule to the oxygen of a different molecule?
a)
amphipathic
b)
hydrophobic
c)
hydrogen bonding
d)
adhesion
33.
Which biomolecule is mainly hydrocarbons and therefore very hydrophobic?
a)
carbohydrate
b)
nucleic acid
c)
protein
d)
lipid
34.
When water is added to split a molecule, the reaction is known as a(n) __ reaction.
a)
dehydration synthesis
b)
condensation
c)
hydrolysis
d)
super magical 
35.
Peptide bonds are formed when _ link to form a polymer.
a)
nucleic acids
b)
amino acids
c)
monosaccharides
d)
polypeptides
36.
Fats & oils are examples of this type of macromolecule
a)
Carbohydrates
b)
Lipids
c)
Proteins
d)
Nucleic Acids
37.
Breads, rice, & pasta are examples of foods that contain this macromoleucle
a)
Carbohydrates
b)
Lipids
c)
Proteins
d)
Nucleic Acids
38.
DNA & RNA are examples of this type of macromolecule.
a)
Carbohydrates
b)
Lipids
c)
Proteins
d)
Nucleic Acids
39.
The three elements that make up most of all 4 types of macromolecules
a)
Water, Oxygen, & Hydrogen
b)
Carbon, Hydrogen, & Oxygen
c)
Nitrogen, Hydrogen, & Oxygen
d)
Nitrogen, Phosphorus, & Sulfur
40.
Which is not a class of macromolecule?
a)
Lipid
b)
Protein
c)
Nucleic Acid
d)
Amino Acid
41.
The structural level of a protein least affected by hydrogen bonds is
a)
primary level
b)
secondary level
c)
tertiary level
d)
all levels are equally affected
42.
Which of these atoms is NOT found in a Carbohydrate?
a)
Carbon (C)
b)
Oxygen (O)
c)
Hydrogen (H)
d)
Phosphorous (P)
43.
What makes up a protein?
a)
Monosaccharide
b)
Amino Acid
c)
Disaccharide
d)
Fatty Acid
44.
Why do lipids provide longer lasting energy than Carbohydrates?
a)
They have many more C-H bonds
b)
They have fewer C-H bonds
c)
They have more Oxygen
d)
They have less Oxygen
45.
Which of these describes a saturated fatty acid?
a)
All C-H bonds are full
b)
They form straight chains
c)
They are solids at room temp.
d)
All of the above
46.
What molecule is this?
a)
this is a monosaccharide
b)
this is a polysaccharide
c)
this is a protein
d)
this is a lipid
47.
Which of the following is the process used to bond the monomers together?
a)
Hydrolysis
b)
Water Removal
c)
Dehydration Synthesis
d)
Water Synthesis
48.
A large molecule made up of many similar or identical subunits. 
a)
Monomer 
b)
Lipids 
c)
Polymer 
d)
Enzyme 
49.
What are the building blocks of a lipid?
a)
3 gylcerols and 1 fatty acid
b)
1 glycerol and 3 fatty acids
c)
3 amino acids
d)
3 simple sugars
50.
Which fatty acid tail is unsaturated?
a)
Only the bottom tail is unsaturated.
b)
Only the top tail is unsaturated.
c)
Both tails are unsaturated.
d)
Neither tail is unsaturated.
51.
Water is polar because...
a)
The unequal sharing of electrons gives the water molecule a slight negative charge near its oxygen atom and a slight positive charge near its hydrogen atoms.
b)
The molecule has two poles, at which the it is colder than other regions of the molecule.
c)
The unequal sharing of electrons gives the water molecule a slight negative charge near its hydrogen atoms and a slight positive charge near its oxygen atom.
d)
The water molecule is neutral.
52.
The 20 different amino acids found in polypeptides exhibit different chemical and physical properties because of different
a)
amino groups attached to an alpha  carbon
b)
asymmetric carbons.
c)
carboxyl groups attached to an alpha  carbon
d)
side chains (R groups).
53.

A covalent chemical bond is one in which

a)

electrons are removed from one atom and transferred to another atom so that the two atoms become oppositely charged.

b)

protons and neutrons are shared by two atoms so as to satisfy the requirements of both atoms.

c)

outer-shell electrons of two atoms are shared so as to satisfactorily fill the outer electron shells of both atoms.

54.

What gives rise to the cohesiveness of water molecules?

a)

hydrophobic interactions

b)

nonpolar covalent bonds

c)

ionic bonds

d)

hydrogen bonds

55.

Which of the following statements is/are true regarding the chemical reaction illustrated in the Figure?

a)

It is a hydrolysis reaction.

b)

It results in a peptide bond.

c)

It joins two fatty acids together.

56.
How do isotopes of the same element differ from each other?
a)
number of protons
b)
number of electrons
c)
valence electron distribution
d)
number of neutrons
57.
Which two functional groups are always found in amino acids?
a)
ketone and aldehyde
b)
hydroxyl and aldehyde
c)
carboxyl and amine
d)
carbonyl and carboxyl
58.
Which molecule is an alcohol?
a)
Molecule A
b)
Molecule B
c)
Molecule C
d)
Molecule D
59.
This is a picture of a?
a)
Polypeptide
b)
Nuceotide
c)
Steroid
d)
Polysaccharide
60.
The monomer of a nucleic acid is
a)
Monosaccharide
b)
Amino Acid
c)
Nucleotide
d)
Fatty Acid
61.
Water has a pH of
a)
6
b)
15
c)
3
d)
7
62.
When atoms combine, they may gain, lose, or share:
a)
protons
b)
electrons
c)
neutrons
d)
nuclei
63.
Water molecules require a lot of energy to separate one from the others.  This gives water a high
a)
density
b)
polarity
c)
solvency
d)
specific heat
64.

Which of the following best describes water's ability to dissolve certain substances such as glucose, but remain separate from other substances such as oils?

a)

Water molecules are polar, consisting of two partially positive hydrogen atoms, and one partially negative oxygen atom.

b)

Water molecules can only form ionic bonds with polar molecules, such as glucose.

c)

Due to hydrogen bonding, water is more dense as a liquid than a solid.

d)

Water has an overall negative charge, which allows it to easily dissolve nonpolar substances like glucose.

65.

Which of the following examples explains how biological activity relies on water's adhesive properties?

a)

Water travels through vascular tissue (xylem) from the roots to the leaves of a plant.

b)

Stomata (openings) in leaves control transpiration of water out of the leaf as water vapor.

c)

Vacuoles in plant cells swell as water dilutes the contents of the vacuole.

d)

Feathers retain an oily coating that repels water droplets.

66.

Given the structure of water (H2O), which of the following must be true?

a)

Each water molecule can form four hydrogen bonds.

b)

Each water molecule will form covalent bonds with its neighbors.

c)

Water has an overall negative charge.

d)

Water is able to easily dissolve nonpolar substances.

67.

Which of the following describes a covalent bond?

a)

It involves an atom that gains an electron.

b)

Two or more atoms share electron pairs.

c)

Molecules linked by covalent bonds are less dense when in solid form than when in liquid form.

d)

A hydrogen atom with a partial positive charge is attracted to another atom with a partial negative charge.

68.

Which of the following statements regarding carbon is FALSE?

a)

Carbon has the capacity to form single and double bonds.

b)

Carbon has the ability to bond together to form extensive branched or unbranched "carbon skeletons."

c)

Carbon has the ability to bond with up to six other atoms.

d)

Carbon has a tendency to form covalent bonds.

69.

Which of the following best describes the role that water plays in the reaction depicted here?

a)

Water catalyzes the formation of a covalent bond in the dimer through hydrolysis.

b)

When water condenses out of the reaction, a dimer is created as a covalent bond forms between two monomers.

c)

When water combines with the two monomers, a dimer forms.

d)

Water is an input of the reaction, leading to the formation of a covalent bond in the dimer product.

70.

Which of the following questions would a researcher most likely ask if they wanted to know whether a hydrolysis reaction or a dehydration synthesis reaction is occurring?

a)

Are the monomers identical to one another?

b)

Is an enzyme involved in the reaction?

c)

Which polymer is involved in the reaction?

d)

Is water a reactant or product of the reaction?

71.

Lactose is a dimer sugar composed of two monomeric subunits (galactose and glucose). In an investigation, researchers placed intestinal cells in a nutrient medium containing lactose. The researchers determined that the lactose had broken down to galactose and glucose in the manner depicted in the reaction shown here.


The cells were then modified and re-exposed to the lactose medium. The researchers were no longer able to detect the presence of galactose and glucose. Which of the following conclusions best explains an outcome of this modification?

a)

The cells were unable to hydrolyze lactose, resulting in the formation of a covalent bond between galactose and glucose.

b)

The cells were unable to hydrolyze the lactose dimer into its monomeric subunits.

c)

The cells were able to perform dehydration synthesis reactions in order to break down lactose into its monomeric subunits.

d)

The cells were able to undergo a reverse reaction and build lactose.

72.

A researcher wants to identify a newly isolated DNA strand. The first step in identifying the DNA strand is to measure its length. To do this, the researcher wants to develop a fluorescent tag that emits light once it binds to both ends of the strand.

Which of the following best describes how the researcher should develop a fluorescent tag with an ability to bind to both ends of the strand?

a)

The tag should have an affinity to bind only guanine (G) and cytosine (C) nitrogenous bases.

b)

The tag should have an affinity to bind only free amino (-NH2) and carboxyl (-COOH) functional groups.

c)

The tag should have an affinity to bind only adenine (A) and thymine (T) nitrogenous bases.

d)

The tag should have an affinity to bind only free 3' hydroxyl (-OH) and 5' phosphate (-PO4) functional groups.

73.

The image depicts how the bacterial protein barnase undergoes modifications that involve changing its conformation, or shape. In order to function in the cell, barnase has to be folded from a nonfunctional conformation into a functional conformation.

a)

The functional conformation of barnase has a tertiary structure because it consists of a polypeptide chain folded into a three-dimensional shape.

b)

The functional composition of barnase has a quaternary structure because it consists of interactions between multiple polypeptide units.

c)

The functional composition of barnase has a secondary structure because it consists of a single alpha-helix.

d)

The functional composition of barnase has a primary structure because it consists of a linear chain of amino acids.

74.

Amino acids can be distinguished from one another by

a)

the number of R groups found on the amino acid molecules.

b)

the type of bond between the R group and the rest of the amino acid molecule.

c)

the chemical properties of their R groups.

d)

the chemical properties of their amino and carboxyl groups.

75.

Which of the following statements about enzymes is false?

a)

They are monomers used to build proteins.

b)

They regulate virtually all chemical reactions in a cell.

c)

They function as chemical catalysts.

d)

They increase the rate of chemical reactions.

76.

Your first big biology exam is coming up in a few days, and in order to prepare for late-night study sessions, you buy a box of Yummies, a delicious type of snack cake. After checking out the nutrition facts label on the side of the box, you discover that a single Yummie cake contains 4.5 grams of total fat, 27 grams of carbohydrate, 0 grams of fiber, and 1 gram of protein.


The pH of the stomach is extremely acidic (~ pH 2). If you ate a Yummie cake, what do you think would happen to the protein that you ingested as it passes through the stomach?

a)

The protein would form longer proteins via dehydration reactions.

b)

The protein would get broken down via dehydration reactions.

c)

The protein would become denatured due to the acidic environment.

d)

The protein would speed up digestion because it is an enzyme.

77.

What is the complementary sequence to the DNA strand TCGATGG?

a)

AGCUACC

b)

AGCTACC

c)

GGTAGCT

d)

TCGATGG

78.

Which of the following correctly matches the macromolecule with its monomer?

a)

carbohydrates: monosaccharides

b)

proteins: polysaccharides

c)

lipids: nucleotides

d)

nucleic acids: polypeptides

79.

In the cell membrane, carbohydrate chains can be covalently linked to membrane proteins to form glycoproteins. They can also be covalently linked to membrane phospholipids to form glycolipids. These two cell membrane structures are shown in the image provided.


During an investigation, researchers discover a new toxin that enters a cell after binding to a carbohydrate on the cell membrane. Which of the following best describes how the toxin attaches to the cell membrane?

a)

The toxin attaches to specific phospholipids on the cell membrane.

b)

The toxin attaches to specific amino acids on the cell membrane.

c)

The toxin attaches to specific fatty acids on the cell membrane.

d)

The toxin attaches to specific monosaccharides on the cell membrane.

80.

Cowpox is classified as a DNA virus because its genome, or genetic material, consists of double-stranded DNA.

Which of the following claims is best supported by the information above?

a)

Cowpox contains a five-carbon sugar called ribose in its nucleic acid structure.

b)

Uracil nucleotides are not found in the cowpox genome.

c)

Cowpox has a single-stranded nucleic acid structure.

d)

Thymine nucleotides are not found in the cowpox genome.

81.

The following excerpt describes a potential origin of the first living cells on earth:


"We have proposed that a simple primitive cell, or protocell, would consist of two key components: a protocell membrane that defines a spatially localized compartment, and an informational polymer that allows for the replication and inheritance of functional information."


Based on this excerpt, which of the following questions would best direct an investigation on whether the "informational polymer" is DNA or RNA?

a)

Which type of bonds connect individual nucleotides in the sugar-phosphate backbone of the informational polymer?

b)

Which nitrogenous bases are present in the structure of the informational polymer?

c)

Which functional group is located on the 3' end of the informational polymer?

d)

Which functional group is located on the 5' end of the informational polymer?

82.

Which of the following molecules is a carbohydrate?

a)

C51H98O6

b)

C22H49O10N5

c)

C45H84O8P4

d)

C60H100O50