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Worksheets

MSSK EMQ MCQ

Total questions: 88

Worksheet time: 1hrs 28mins

Name
Class
Date
1.

A patient with advanced bladder carcinoma suffers from difficulty while walking. Examination reveals weakened adduction of the right thigh. This nerve that supplies the

a)

Obturator externus

b)

Tibialis anterior

c)

Adductor magnus

d)

Semintendinosus

2.

CT scan examination of a patient presenting with complaints of a painful knee & difficulty in walking, reveals a very large cyst in the popliteal fossa compressing the tibial. This muscle is most likely to be involved.

a)

obturator externus

b)

tibialis anterior

c)

semitendinosus

d)

adductor magnus

3.

This is the prominent osteophyte at distal interphalangeal joint.

a)

Heberden node

b)

Bouchard node

c)

Swan neck deformity

d)

Boutounniere deformity

4.

Impingement of spiral foramina by osteophytes can cause this clinical feature.

a)

Neurological deficit

b)

Dysplastic nevus

c)

Muscle atrophy

d)

Muscle spasm

5.

A 59 y/o man, a known case of carcinoma of stomach, was also noted to have hyperpigmented verrucous plaques lesions over the back of neck & axillary folds.

a)

Acanthosis nigricans

b)

Dysplastic nevus

c)

Seborrheic keratosis

d)

Systemic Lupus Erythematosus

6.

A 77 y/o man has a lesion on his right side of his face. The lesion enlarged slowly over the past 5 years. On examination, the 3 cm lesion has irregular border, variegated brown to black pigmentation & bleeding.

a)

Seborrheic keratosis

b)

Acanthosis nigricans

c)

Dysplastic nevus

d)

Ephelis

7.

10 y/o girl has flat, uniform black skin lesion measuring about 2cm on right buttock

a)

Freckle (ephelis)

b)

Seborrheic keratosis

c)

Acanthosis nigricans

d)

Xeroderma pigmentosa

8.

73 y/o man has a demarcated uniform brown pigmented papule over the trunk for 20 years, which is slowly enlarging. He was told by his doctor that he has the most common benign epidermal tumor.

a)

Seborrheic keratosis

b)

Acanthosis nigricans

c)

Dysplastic nevus

d)

Scalded skin syndrome

9.

This substance promotes the activation of immune system.

a)

interleukin

b)

fibronectin

c)

hydroxycloroquine

d)

toxoid

10.

This is an opsonin that helps in phagocytosis.

a)

interleukin

b)

fibronectin

c)

toxoid

d)

immune serum globulin

11.

Exogenous antigens broken down to peptides are bound to this.

a)

MHC Class II

b)

MHC Class I

c)

CD4+

d)

CD8+

12.

This is found in the epidermis & can present antigens.

a)

Langerhans cell

b)

Dendritic cell

c)

Macrophage

d)

Monocyte

13.

This condition is caused when autoantibodies are formed against DNA & the patients present with characteristic ‘butterfly rash’.

a)

Systemic lupus erythematosus

b)

Acanthosis nigricans

c)

Xeroderma pigmentosa

d)

Scalded skin syndrome

14.

Patients with this condition develop autoantibodies against receptors for thyroid-stimulating hormone (TSH).

a)

Graves disease

b)

Myasthenia gravis

c)

Goodpasture's disease

d)

Systemic lupus eryhtematosus

15.

This vaccine is not suitable to be administered to immunocompromised individuals.

a)

live attenuated vaccine

b)

peptide subunit vaccine

16.

This vaccine utilizes specific epitopes of microbial protein to bring about desired immune response.

a)

live attenuated vaccine

b)

peptide subunit vaccine

17.

Extensive sloughing of the epidermal cells caused by the bacterial toxin leads to this condition.

a)

scalded skin syndrome

b)

acanthosis nigricans

c)

ephelis

d)

SLE

18.

Skin and soft tissue infections: This condition is common among adolescents & young adults.

(a)  

19.

This parasite can cause post kala-azar dermal lesions.

a)

strongyloides stercoralis

b)

ancylostoma caninum

c)

leishmania donovani

d)

austrobilharzia variglandis

20.

This parasite can cause cutaneous larva migrans.

a)

ancylostoma caninum

b)

leishmania donovani

c)

strongyloides stercoralis

d)

sarcoptes scabiei

21.

Prolonged use of this drug is known to cause fibrosis & cirrhosis of liver.

a)

methotrexate

b)

baclofen

c)

aspirin

d)

infliximab

22.

This drug is a monoclonal antibody that neutralizes the biological activity of TNF-alpha.α.

a)

infliximab

b)

methotrexate

c)

baclofen

d)

aspirin

23.

The patient had history of injury to the right side of his chest wall. During physical examination, he was asked to push both his hands against the wall. His right scapula stood out like a wing. This nerve is most likely to be injured.

a)

long thoracic nerve

b)

median nerve

c)

ulnar nerve

d)

radial nerve

24.

A typist complained of burning pain along the palmar aspect of the skin of her lateral three and a half fingers. This nerve is likely to be compressed.

a)

median nerve

b)

long thoracic nerve

c)

ulnar nerve

d)

radial nerve

25.

Drug can cause Reye Syndrome if administered to a child suffering from viral fever.

a)

aspirin

b)

paracetamol

c)

celecoxib

d)

colchicine

26.

Drug can be used parenterally as a morphine substitute to reduce post-operative pain because its analgesic action is more than its anti-inflammatory action.

a)

ketorolac

b)

baclofen

c)

aspirin

d)

paracetamol

27.

45 y/o teacher suffered from prolapsed intervertebral disc after lifting a heavy baggage. The affected joint is categorized under this type.

a)

primary cartilaginous joint

b)

secondary cartilaginous joint

c)

fibrous joint

d)

synovial joint

28.

Patient had difficulty in locking & unlocking the door. Examination of his hand muscles revealed no abnormality. The affected joint is categorized under this type.

a)

synovial ellipsoidal joint

b)

synovial ball-and-socket joint

c)

cartilagenous joint

d)

fibrous joint

29.

Patient fell to the left side when he tried to stand only on his right foot. The weakened hip abductors of the right side are supplied by this nerve.

a)

inferior gluteal nerve

b)

sciatic nerve

c)

fibular nerve

d)

tibial nerve

30.

Patient was unable to raise his right foot after he  received an intramuscular injection. This nerve could have been injured.

a)

sciatic nerve

b)

inferior gluteal nerve

c)

tibial nerve

d)

fibular nerve

31.

Secretion of this hypocalcaemic hormone shows a direct linear relationship with plasma calcium.

a)

calcitonin

b)

parathyroid hormone

32.

Secretion of this hypercalcaemic hormone shows an inverse linear relationship with plasma calcium.

a)

calcitonin

b)

parathyroid hormone

33.

Phosphate binds with this to form a complex that triggers events of smooth muscle.

a)

myosin light chain kinase

b)

calmodulin

c)

myosin light chain phosphatase

d)

calcequestrin

34.

Binding of alpha-GTP with this will produce 2 seconds messengers.

a)

phospholipase C

b)

phospholipase D

c)

phospholipase B

d)

phospholipase A2

35.

During excitation of nerve impulse, calcium is released & binds to this protein inside the sarcoplasmic reticulum.

a)

calsequestrin

b)

calcineurin

c)

calmodulin

d)

caldesmon

36.

This calmodulin regulating protein plays an important role in regulating both slow & fast twitch muscle fibres.

a)

calcineurin

b)

calmodulin

c)

calsequestrin

d)

caldesmon

37.

Patient with colorectal cancer was treated with a combination of chemotherapeutic drugs, which include 5-fluorouracil (5-FU). 5-FU is inhibited by this enzyme.

a)

thymidylate synthase

b)

dihyrofolate reductase

c)

adenosine deaminase

d)

PRPP synthethase

38.

1 y/o boy had an immune disorder where both B cells and T cells are deficient with an accumulation of adenosine & dATP. This enzyme deficiency may lead to severe combined immunodeficiency disease (SCID).

a)

adenosine deaminase

b)

thymidylate synthase

c)

dihydrofolate reductase

d)

PRPP synthetase

39.

A 2 week- break of endurance training affects this drastically.

(a)  

40.

This central adaptation has a direct effect in supplying oxygen to the exercising muscles.

a)

increased red blood cell count

b)

decreased red blood cell count

c)

increased white blood cell count

d)

decreased white blood cell count

41.

10 y/o boy developed multiple skin lesions on his feet with pustular bullae & crusted black necrosis. Culture of the pus grew beta haemolytic colonies. This is likely cause of the infection.

a)

streptococcus pyogenes

b)

staphylococcus aureus

c)

neisseria gonorrhea

d)

microsporum canis

42.

35 y/o woman reported to the physician that she feels fine in the morning but experiences drooping of her upper eyelids & weakness of muscles in the extremities during late afternoon. This is the most probable diagnosis.

a)

myasthenia gravis

b)

good pasture's disease

c)

graves disease

d)

rheumatoid arthritis

43.

A patient developed Klumpke Palsy after he tried to catch hold of a tree branch when he fell from height. This part of the brachial plexus is injured.

a)

lower trunk

b)

upper trunk

44.

Accelerated de novo purine nucleotide biosynthesis in the Lesch-Nyhan Syndrome is most probable due to this.

Increased availability of (a)  

45.

Peri-umbilical distribution of lesions resembling ‘thumb prints’ is characteristic of massive migration of this parasite.

a)

strongyloides stercoralis

b)

ancylostoma caninum

c)

austrobilharzia variglandis

d)

sarcoptes scabiei

46.

Subcapsular sinuses are seen in this lymphatic organ/tissue.

(a)  

47.

The following cells can present an antigen except:

a)

monocyte

b)

macrophage

c)

B lymphocyte

d)

dendritic cell

48.

The medial meniscus is more frequently torn in injuries than the lateral meniscus because it is firmly attached to one of the following structures:

a)

medial collateral ligament

b)

posterior cruciate ligament

c)

anterior cruciate ligament

d)

patellar tendon

49.

This artery is a branch of the 2nd part of the axillary artery.

a)

thoracoacromial

b)

subclavian

c)

brachial

50.

This cell surface marker is found on cytotoxic T lymphocytes.

a)

CD8+

b)

CD4+

c)

MHC Class I

d)

MHC Class II

51.

This clinical condition is due to fusion of joint-ends with calcification.

a)

bony ankylosis

b)

fibrous ankylosis

c)

osteoarthritis

d)

osteomyelitis

52.

This confers passive immunity

a)

toxoid

b)

interleukin

c)

calcineurin

d)

immune serum globulin

53.

This drug inhibits the microtubules & prevents the diapedesis of neutrophils to the inflammatory site.

a)

colchicine

b)

indomethacin

c)

aspirin

d)

methotrexate

54.

This drug if administered to a pregnant woman after 32 weeks, can prematurely close patent ductus arteriosus in the fetus.

a)

indomethacin

b)

aspirin

c)

celecoxib

d)

colchicine

55.

This enzyme catalyses the rate limiting step of pyrimidine synthesis where cytidine triphosphate ( CTP) exhibits allosteric inhibition.

a)

aspartate trasncarbamoylase

b)

PRPP synthetase

c)

adenosine deaminase

d)

guanine deaminase

56.

This is exchanged with calcium in the plasma against concentration gradient that contributes to cardiac muscle relaxation.

a)

Na+

b)

K+

c)

PO42-

57.

This is the most reliable landmark to identify the femoral veins.

Femoral vein lies _____ to femoral artery

a)

medial

b)

anterior

c)

posterior

d)

lateral

58.

Type of skin lesion that is premalignant.

a)

actinic keratosis

b)

acanthosis nighricans

c)

xeroderma pigmentosa

d)

scalded skin syndrome

59.

True regarding stretch reflex.

a)

Has type Ia afferent nerve fibers

b)

Has type Ib afferent nerve fibers

c)

Polysynaptic (disynaptic)

d)

Effector is flexor

60.

Portion of Ab fixes compliment.

a)

Fc

b)

Fab

61.

Type of malignant skin lesions that is only locally invasive.

a)

basal cell carcinoma

b)

squamous cell carcinoma

c)

melanocytic nevi

d)

ephelis

62.

location of thymic dependent

a)

paracortex

b)

postcapillary venules

c)

medulla

d)

subscapular sinus

63.

This causes Reye's syndrome in children with viral fever

a)

indomethacin

b)

aspirin

c)

paracetamol

d)

celecoxib

64.

This drug will cause hepatotoxicity to the liver and leads to fibrosis and cirrhosis to the liver in the long-term use.

a)

methotrexate

b)

aspirin

c)

paracetamol

d)

celecoxib

65.

Swelling and have multinucleated giant cell

a)

osteoclastoma

b)

osteochondroma

c)

osteoblastoma

d)

osteosarcoma

66.

This drug is an anti tnf-a monoclonal antibody which neutralises tnf-a antibody

a)

infliximab

b)

baclofen

c)

aspirin

d)

methrotrexate

67.

Cell that induced apoptosis of cell.

a)

CD4+

b)

CD8+

68.

this drug have more analgesic effect than opioid

a)

ketorolac

b)

celecoxib

c)

baclofen

d)

aspirin

69.

Hormone that produce by parafollicular c cell of thyroid gland

a)

calcitonin

b)

parathormone

c)

calcitriol

70.

What parasite that burrow on upper layer of the skins and cause rash frequently on the webbing of the finger

a)

sarcoptes scabiei

b)

ancylostoma caninum

c)

austrobilharzia variglandis

d)

strongyloides stercoralis

71.

Full elevation of arm to 180° by which muscle?

a)

serratus anterior

b)

deltoid

c)

brachioradialis

72.

The patient had injury at his thumb involving the carpo-metacarpal joint. This carpal joint likely to be fractured

 

a)

trapezium

b)

pisiform

c)

scaphoid

d)

trapezoid

73.

Type of benign lesion and also known as freckle

a)

ephelis

b)

actinic keratosis

c)

acanthosis nigricans

d)

xeroderma pigmentosa

74.

50 year old male patient presented with intense redness, heat and pain over his right great toe at metatarsophalangeal joint. Fluid from this joint showed birefringent crystals on polaroid light microscopy. These features might have developed due to degradation of excessive amount of this

a)

adenine

b)

guanine

c)

cytosine

d)

thymine

75.

Charecteristic of type 1 muscle fiber

Resistant to (a)  

76.

Insertion site of flexor digitorum muscles?

a)

Phalanges

b)

Ulnar

c)

Radius

d)

Humerus

77.

An 18 year old boy consulted a doctor for mild pain and swelling for his right knee for last 15 days. Histopathological picture of this lesion shows plump pleomorphic cells with osteoid formation.

a)

osteosarcoma

b)

osteochondroma

c)

osteoblastoma

d)

osteochondroma

78.

This inhibit microtubules and prevent diapedesis of neutrophil to inflammatory sites

a)

colchicine

b)

methotrexate

c)

celecoxib

d)

aspirin

79.

Acetylcholine receptors are located at this site.

a)

sarcolemma

b)

sarcoplasmic reticulum

c)

terminal cisternae

d)

T-tubule

80.

Calcium ions that trigger events of muscle contraction are released from this.

a)

sarcoplasmic reticulum

b)

sarcolemma

c)

T-tubule

d)

terminal cisternae

81.

Excess post-exercise oxygen consumption (EPOC) is not used for this

a)

hormone balancing

b)

storage of glycogen

c)

cellular repair

d)

innervation

82.

Transfer of antibodies from mother to child is an example for this mode of acquiring immunity.

a)

passive natural

b)

active natural

c)

active artificial

d)

passive artificial

83.

This hormone is essential to maintain normal plasma calcium between 3 mg/dL to 10 mg/dL

a)

parathormone

b)

calcitriol

c)

calcitonin

84.

 

Compression of this nerve leads to carpal tunnel syndrome.

a)

median nerve

b)

ulnar nerve

c)

radial nerve

d)

musculocutaneous nerve

85.

This is the normal articulation of hand as seen on X-ray.

(a)   articulates with the radius

86.

Smooth muscle contraction is initiated when Ca2+ bind mainly to this.

a)

calmodulin

b)

calsequestrin

c)

caldesmon

87.

This substance provides an anti-viral state to uninfected cells during viral infection.

a)

interleukin

b)

interferons

c)

calcineurin

88.

This influences the initiation of liver glycogenolysis.

a)

glucose-6-phosphatase

b)

HGPRTase

c)

APRTase

d)

PRPP synthetase