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anti depressants

Total questions: 110

Worksheet time: 55mins

Name
Class
Date
1.

1. Specify antidepressant:

a)

carbidopa

b)

sodium thiopental

c)

amitriptyline

d)

phenobarbital

e)

levodopa

2.

2. Tricyclic antidepressant

a)

paroxetine

b)

moclobemide

c)

fluoxetine

d)

amitriptyline

e)

pyridrol

3.

3. Drug for the treatment of depression:

a)

amitriptyline

b)

aminazine

c)

haloperidol

d)

lithium carbonate

e)

clonazepam

4.

4. Indications for the use of fluoxetine :

a)

insomnia

b)

anorexia

c)

depression

d)

schizophrenia

e)

alcoholism

5.

5. An antidepressant-non-selective monoamine oxidase inhibitor ( MAO-A and MAO-B) is

a)

maprotiline

b)

fluoxetine

c)

moclobemide

d)

amitriptyline

e)

nialamide

6.

6. An antidepressant-selective monoamine oxidase inhibitor (MAO-A) is:

a)

maprotiline

b)

moclobemide

c)

fluoxetine

d)

amitriptyline

e)

nialamide

7.

7. Depression is treated with the following group:

a)

antidepressants

b)

mood stabilizers

c)

neuroleptics

d)

tranquilizers

e)

psychotherapy

8.

8. Side effect of amitriptyline:

a)

stimulation of the central nervous system

b)

parkinsonism

c)

anticholinergic effect

d)

bradycardia

e)

miosis

9.

9. An antidepressant that blocks the neuronal uptake of norepinephrine

a)

maprotiline

b)

paroxetine

c)

imipramine

d)

nialamide

e)

moclobemide

10.

0. A patient with depression was prescribed a drug. On the third day of taking the medicine, the patient

had dinner at a restaurant, the table included lamb, red wine and cheese. 2 hours after dinner, the

patient’s blood pressure rose sharply and tachycardia developed. Which drug was most likely prescribed

to the patient?

a)

fluoxetine

b)

diazepam

c)

prednisolone

d)

maprotiline

e)

nialamide

11.

11. Select a selective crue that blocks the neuronal uptake of serotonin:

a)

fluoxetine

b)

nialamide

c)

amitriptyline

d)

maprotiline

e)

tyramine

12.

12. Specify the mechanism of action of nialamide

a)

inhibits cholinesterase

b)

inhibits catechol - o - methyltransferase (COMT)

c)

inhibits monoamine oxidase (MAO )

d)

inhibits adenylate cyclase

e)

inhibits phospholipase

13.

13. Fluoxetine:

a)

stimulates dopamine receptors

b)

MAO-A inhibitor

c)

disrupts the neuronal reuptake of serotonin

d)

increases the content of gamma-aminobutyric acid (GABA) in the central nervous system

e)

bewakoof matarr > akalmand tamatarrr

14.

14. Specify the main effect of nialamide

a)

reduces symptoms of depression

b)

suppression of fear, anxiety

c)

suppression of delusions, hallucinations

d)

promotes sleep

e)

reduces motor activity

15.

15. The combination of Paroxetine is contraindicated with:

a)

antacids

b)

antispasmodics

c)

non-selective MAO inhibItors

d)

antibiotics

e)

NSAIDS

16.

16. Which antidepressants have the following side effects such as headache, insomnia, agitation, dry

mucous membranes, tachycardia, dyspeptic disorders:

a)

inhibitors of neuronal serotonin uptake

b)

tricyclic antidepressants

c)

Inhibitors of neuronal norepinephrine uptake

d)

MAO inhibitors

e)

inhibitors of presynaptic alpha-2 adrenergic receptors

17.

7. Name a tricyclic antidepressant that differs in the positive direction by the absence of

M-anticholinergic properties. It is used for mild to moderate depression:

a)

amitriptyline

b)

imipramine

c)

clomipramine

d)

paroxetine

e)

pipofezin

18.

18. Patient M., 45 years old, suffers from pathologically low mood, with ideas of self-blame, suicidal

thoughts and anxiety. Select a drug for treatment:

a)

diazepam

b)

phenobarbital

c)

chloropyramine

d)

amitriptyline

e)

piracetam

19.

19. MAO-A primarily inactivates:

a)

dopamine

b)

norepinephrine and serotonin

c)

serotonin

d)

norepinephrine

e)

bradykinin

20.

20. For the treatment of depression, patient G., 45 years old, was prescribed maprotiline . Select the

mechanism of action of the drug:

a)

blocks dopamine receptors

b)

increases the affinity of GABA receptors for GABA

c)

blocks MAO

d)

blocks the reuptake of monoamines

e)

blocks the neuronal reuptake of serotonin

21.

21. Patient F., 62 years old, was prescribed a drug for the treatment of depression; after some time the

patient began to complain of dry mouth, urinary retention, dilated pupils, blurred vision, and hand tremors.

What pharmacological group of drugs could cause these side effects?

a)

tricyclic antidepressants

b)

blocking the neuronal uptake of serotonin

c)

blocking the neuronal uptake of norepinephrine

d)

MAO-A inhibitors

e)

MAO-B inhibitors

22.

22. A 42-year-old woman consulted a doctor with complaints of worsening appetite, sleep disturbances, a

feeling of extreme fatigue and loss of strength and anxiety. Laboratory and instrumental examination

revealed no pathology. Prescribe treatment.

a)

amitriptyline

b)

lithium carbonate

c)

aminazine

d)

carbamazepine

e)

there are no indications for prescribing any medications

23.

23. A 55-year-old man is brought to the emergency department by ambulance after experiencing severe

tremors, confusion, and agitation. Paramedics report that the patient has a history of depression and is

currently taking an MAO inhibitor. His wife reports that he has not been feeling well for the past few days

and has started taking a new medication for depression. Which pharmacological group of drugs caused

side effects in the patient?

a)

SPVA

b)

methylxanthine derivatives

c)

psychostimulants

d)

neuroleptics

e)

SSRIs, TCAs, SNRIs

24.

24. Indications for the use of fluoxetine

a)

insomnia

b)

anorexia

c)

depression

d)

alcoholism

e)

schizophrenia

25.

25. An antidepressant-non-selective monoamine oxidase inhibitor ( MAO-A and MAO-B) is:

a)

moclobemide

b)

amitriptyline

c)

maprotiline

d)

nialamide

e)

fluoxetine

26.

26. An antidepressant-selective monoamine oxidase inhibitor (MAO-A) is:

a)

maprotiline

b)

moclobemide

c)

fluoxetine

d)

amitriptyline

e)

nialamide

27.

27. Depression is treated with the following group:

a)

neuroleptics

b)

antidepressants

c)

mood stabilizers

d)

tranquilizers

e)

psychotherapy

28.

28. Side effect of amitriptyline.

a)

stimulation of the central nervous system

b)

anticholinergic effect

c)

anticholinergic effect

d)

bradycardia

e)

miosis

29.

29. An antidepressant that blocks the neuronal uptake of norepinephrine:

a)

imipramine

b)

paroxetine

c)

moclobemide

d)

maprotiline

e)

nialamide

30.

30. Select a selective drug that blocks the neuronal uptake of serotonin:

a)

fluoxetine

b)

nialamide

c)

amitriptyline

d)

maprotiline

e)

tyramine

31.

1. Specify long acting benzodiazepine anxiolytic:

a)

Naloxone

b)

Lorazepam

c)

Phenazepam

d)

Buspirone

e)

Midazolam

32.

2. Specify benzodiazepine Medium-acting anxiolytic:

a)

Phenazepam

b)

Lorazepam

c)

Diazepam

d)

Ropinirole

e)

Buspirone

33.

3. "Daytime tranquilizer", a benzodiazepine derivative

a)

Diazepam

b)

Gabapentin

c)

Midazolam

d)

Phenazepam

e)

Medazepam

34.

4. Anxiolytic - agonist of serotonin receptors:

a)

Buspirone

b)

Amizil

c)

Lorazepam

d)

Chlordiazepoxide

e)

Diazepam

35.

5. Anxiolytic with a central H-histamine blocker effect :

a)

Hydroxyzine

b)

Buspirone

c)

Medazepam

d)

Amizil

e)

Phenazepam

36.

6. The action of benzodiazepines is mediated by:

a)

GABA

b)

Serotonin

c)

Acetylcholine

d)

Norepinephrine

e)

Dopamine

37.

7. Reducing internal tension, eliminating anxiety, fear is called

a)

Antidepressant

b)

Sedative

c)

Neuroleptic

d)

Anticonvulsant

e)

Anxiolytic

38.

8.Specific benzodiazepine receptor antagonist:

a)

Galopidol

b)

Diazepam

c)

Flumazenil

d)

Naphazoline

e)

Chlorpromazine

39.

9. benzodiazepine receptor agonist except

a)

Diazepam

b)

Hydroxyzine

c)

Phenazepam

d)

Medazepam

e)

Nitrazepam

40.

10. A 3-year-old child was admitted to the intensive care unit with severe atony of skeletal muscles,

and tomus, respiratory depression and collapse. According to her mother, she takes pills due to

neurosis and forgot to remove them after taking them. After a while she discovered the medicine

next to a child who lies and does not breathe. The child was suspected of benzodiazepine poisoning.What should be administered to neutralize the effect of the drug?:

a)

Atropine

b)

Naloxone

c)

Amisil

d)

Flumazenil

e)

Phenobarbital

41.

11. The following effects are typical for benzodiazepine drugs

a)

Anxiolytic , antipsychotic. anticonvulsant

b)

sedative, hypnotic, antiparkinsonian

c)

amnestic, muscle relaxant, analgesic

d)

antidepressive, anticonvulsant, amnestic

e)

muscle relaxant, anticonvulsant, hypnotic

42.

12. Receptor structures with which buspirone interacts

a)

GABA-A receptors

b)

M- cholinergic receptors

c)

5-HT1A

d)

5-HT2 and histamine receptor

e)

NMDA receptors

43.

13. Anxiolytic which lacks sedative, anticonvulsant and muscle-relaxing effects:

a)

Buspirone

b)

Hydroxyzine

c)

Amitriptyline

d)

Phenazepam

e)

Flumazenil

44.

14. With chloride ion channels under the influence of anxiolytics, benzodiazepine series occurs

a)

Full block

b)

Longer opening

c)

More frequent opening

d)

Partial block

e)

Doesn't change

45.

15. The main mechanism of action of phenazepam is associated with;

a)

excitation of barbiturate receptors by the benzodiazepine -barbiturate- GABAergic complex

b)

Excitation of omega-1, omega-2, omega-5 benzodiazepine receptors benzodiazepine -barbiturate

- GABAergic complex

c)

Inhibition of GABA transferase

d)

reduced permeability of ca 2+ channels

e)

reduced Na + permeability channels

46.

16. The anxiolytic effect of phenazepam is associated with the effect on:

a)

Medulla

b)

Extrapyramidal system

c)

Mesolimbic system

d)

sympathetic nervous system

e)

Hypothalamus

47.

17. The muscle relaxant effect of benzodiazepines is due to:

a)

Blockade of M- cholinergic receptors of the extrapyramidal system

b)

Direct effect on skeletal muscle myofibrils

c)

Strengthening the inhibitory effects of intercalary GABAergic neurons on motor neurons of the

spinal cord

d)

Suppression of the limbic system

e)

Inhibition of the reticular formation

48.

18.When benzodiazepine receptors are excited, which ion channels open?

a)

Chlorine

b)

Sodium

c)

Magnesium

d)

Calcium

e)

Potassium

49.

19. The main indication for prescribing anxiolytics is

a)

Psycho-emotional stress, phobias

b)

Artenal hypertension

c)

Convulsive syndrome

d)

Myasthenic syndrome

e)

Mania

50.

20. As a result of long-term use of the drug by the patient to eliminate increased irritability against

the background of a positive therapeutic effect, general weakness, lethargy, tachycardia, dry mouth,and numbness of the tongue. What drug did the patient take?

a)

Buspirone

b)

Phenazepam

c)

Amizil

d)

Diazepam

e)

Midazolam

51.

21. A 46-year-old patient, a van driver, became nervous and irritable after an accident. Select a drugfrom the group of anxiolytics, taking into account the patient's profession:

a)

Diazepam

b)

Nitrazepam

c)

Phenazepam

d)

Medazepam

e)

Lorazepam

52.

22. Determine the group of drugs: They reduce feelings of fear, tension, anxiety, are able to relax

skeletal muscles, reduce motor activity, potentiate the effect of sleeping pills and narcotics. They donot eliminate delusions and hallucinations; they should not be prescribed the day before or during work to drive or person whose work involves the need for a quick reaction:

a)

Antipsychotics

b)

Anxiolytics

c)

Antidepressants

d)

Sedatives

e)

Sleeping pills

53.

23. A 15-year-old teenager consulted a doctor with complaints of constant restlessness, anxiety,

insomnia, and nervousness. He connects his condition with the death of his father. What drug can be recommended to a patient to eliminate feelings of internal tension?

a)

Oxazepam

b)

Diazepam

c)

Haloperidol

d)

Clozapine

e)

Aminazine

54.

24. Mechanism of action of hydroxyzine:

a)

Excitation of omega-1, omega-2, omega-5 benzodiazepine receptors benzodiazepine-barbiturate- GABAergic complex

b)

Inhibits GABA transferase

c)

Blocks 5-HT1A serotonin receptors

d)

Stimulates 5-HT1A serotonin receptors

e)

Competitive blockade of H1 histamine receptors

55.

25. Anxiolytic with a central H- histamine blocker effect:

a)

Buspirone

b)

Hydroxyzine

c)

Phenazepam

d)

Medazepam

e)

Amizil

56.

26. The action of benzodiazepines is mediated by:

a)

Norepinephrine

b)

Acetylcholine

c)

Dopamine

d)

GABA

e)

Serotonin

57.

27. Reducing internal tension, eliminating anxiety, fear is called

a)

Antidepressant

b)

Sedative

c)

Neuroleptic

d)

Anxiolytic

e)

Anticonvulsant

58.

28. Specific benjodiatepire receptor antagonist

a)

Chlorpromazine

b)

Naphazoline

c)

Flumazenil

d)

Diazepam

e)

Galopidol

59.

29. benzodiazepine receptor agonist except

a)

Phenatepam

b)

Diazepam

c)

Hydroxyzine

d)

Medazepam

e)

Nitratepam

60.

30. Receptor structures with which buspirone interacts:

a)

NMDA receptors

b)

5-HT2 and histamine receptors

c)

5-HT1A

d)

M- cholinergic receptors

e)

GABA-A receptors

61.

1. Receptor structures whose activity is modulated by benzodiazepine derivatives:

a)

H2 receptors

b)

H1 receptors

c)

GABA receptors

d)

HT2 receptors

e)

Omega 1 receptors

62.

2. An antiepileptic drug, the mechanism of action of which is to activate the

GABAergic system:

a)

Phenytoin

b)

Ethosuximide

c)

Atenolol

d)

Phenobarbital

e)

Lamotrigine

63.

3. The mechanism of action of Selegiline is:

a)

Inhibition of MAO B

b)

Stimulation of dopamine receptors

c)

Blocking NMDA receptors

d)

Blocking dopamine receptors

e)

Replenishment of dopamine deficiency

64.

4. According to the mechanism of action, Biperiden belongs to

a)

Dopamine precursors

b)

Monoamine oxidase B inhibitors

c)

Dopamine receptor agonists

d)

Drugs that inhibit cholinergic effects

e)

Monoamine oxidase A inhibitors

65.

5. What drugs are used to treat Parkinson’s disease

a)

Trihexyphenidyl and chlorpromazine

b)

Chlorpromazine and levodopa

c)

Levodopa and trihexyphenidyl

d)

Chlorpromazine and haloperidol

e)

Carbamazepine and valproic acid

66.

6. Which groups of drugs most often cause drug-induced parkinsonism

a)

Tranquilizers

b)

Analgesics

c)

Anticonvulsants

d)

Neuroleptics

e)

Sleeping pills

67.

7. Amantadine is used as:

a)

Sleeping pills

b)

Antiemetic

c)

Antiparkinsonian drug

d)

Analgesic

e)

Antileptic drug

68.

8. Mechanism of action of anticonvulsants:

a)

Reduces vascular permeability, helps restore microcirculation

b)

Increases the density of the vascular wall, reduce exudation

c)

Increases cerebral blood flow, improves oxygen supply to the brain

d)

Improve the metabolism of brain cells , increase the resistance of cells to

hypoxia

e)

By stabilizing neuron membranes, they inhibit interneuronal transmission of

excitation

69.

9. Patient K, 55 years old, was diagnosed with Parkinson's disease for the first time.

Recommend the patient a drug from the group of MAO inhibitors to start

pharmacotherapy. What drug is this?

a)

carbidopa

b)

Levodopa

c)

Amantadine

d)

Pramipexole

e)

Selegiline

70.

10. The patient suffers from clonic-tonic convulsions. To prevent epileptic

seizures, a drug was prescribed, which had to be discontinued. A

contraindication for prescribing this drug was the detection of II-Ill degree AV

block on the ECG. What drug is this?

a)

sodium channel blocker difenin

b)

activators GABA-sodium valproate

c)

benzodiazepine receptor agonist - diazepam

d)

calcium channel blocker T type ethosuximide

e)

inhibitors of the glutamatergic system – topiramate

71.

11. Select groups of drugs used to treat Parkinson's disease

a)

anticoagulants and antiplatelet agents;

b)

muscle relaxants and NSAIDs

c)

neuroleptics

d)

anticholinesterase drugs;

e)

dopamine precursors;

72.

12. The classic triad of Parkinson's disease includes:

a)

tremor, rigidity, bradykinesia

b)

tremor, rigidity, depression;

c)

rigidity, anosmia, agitation

d)

bradykinesia, rigidity, mental disorders;

e)

anosmia, tremor, postural instability;

73.

13. Antiepileptic drug, sodium channel blocker:

a)

Ethosuximide

b)

Phenobarbital

c)

Phenytoin

d)

Clonazepam

e)

sodium valproate

74.

14. For the treatment of grand mal seizures of epilepsy, use

a)

Phenobarbital

b)

Zopiclone

c)

Bromhexine

d)

Trimethine

e)

Carbamazepine

75.

15. Antiepileptic drug, the use of which may develop hyperplastic gingivitis:

a)

Chlorakon

b)

Phenytoin

c)

Carbamazepine

d)

Trimethin

e)

Sodium valproate

76.

16. Amantadine is used as:

a)

Antiepileptic drug

b)

Analgesic

c)

Antiparkinsonian drug

d)

antiemetic

e)

Sleeping pills

77.

17. Drugs used for drug-induced parkinsonism

a)

Biperidin

b)

Levodopa

c)

Selegiline

d)

Amantadine

e)

pirenzipine

78.

18. For grand mal seizures , a drug is prescribed whose action is combined with a favourable psychotropic effect

a)

Levodopa

b)

Carbamazepine

c)

Phenobarbital

d)

rispolept

e)

Gabapentin

79.

19) Status epilepticus is a dangerous condition when attacks follow each other.

Diazepam may be the drug of choice. Select an effect uncharacteristic of diazepam:

a)

short action

b)

risk of respiratory depression

c)

occurrence of hypotension

d)

blocks sodium channels of neurocytes

e)

causes muscle relaxation

80.

20. A patient with Parkinson's disease is prescribed medication a drug that caused

tachycardia, difficulty urinating, and worsened glaucoma. What drug are we talking

about?

a)

Trihexyphenidyl

b)

Levodopa

c)

Bromocriptine

d)

Selegiline

e)

amantadine

81.

21. Specify a drug that is a dopamine receptor agonist

a)

Selegiline

b)

Bromocriptine

c)

Levodopa

d)

Tolcapone

e)

amitriptyline

82.

22. Specify a drug that stimulates the release of dopamine and inhibits its neuronal reuptake

a)

Tolcapone

b)

Amantadine

c)

Selegiline

d)

Carbidopa

e)

Bromocriptine

83.

23. Specify the effects caused by the anticholinergic activity

of trihexyphenidy

a)

Appetite disturbances

b)

Swelling

c)

Visual hallucinations

d)

Increased intraocular pressure

e)

bradycardia

84.

24. An anticonvulsant that also has an analgesic effect in trigeminal neuralgia

a)

Sodium valproate

b)

Phenytoin

c)

Hexamidine

d)

Carbamazepine

e)

tiagabine

85.

25 . Select indications for prescribing sodium valproate

a)

Grand anal seizure

b)

Manic state

c)

Depressive syndrome

d)

Parkinson’s disease

e)

Meniere’s disease

86.

26. A GABAergic drug, with long term use of which there is a risk of accumulation and severe dependence

a)

Difenin

b)

Phenobarbital

c)

Phenobarbital

d)

Zopiclone

e)

Amitriptyline

87.

27. Diphenin has, in addition to the main effect:

a)

Antiarrhythmic , analgesic, muscle relaxant effects

b)

Neuroleptic , sedative, adrenergic blocking effects

c)

Sedative , depressant, calming effects

d)

M-anticholinergic, anxiolytic, antidepressant effects

e)

psychostimulating , antispasmodic , antiemetic effects

88.

28. Specify a peripheral DOPA decarboxylase inhibitor, the use of which in the treatment of parkinsonism neutralizes the side effects of levodopa:

a)

Carbidopa

b)

Benserazide

c)

Domperidone

d)

Clozapine

e)

aminazine

89.

29. A 51-year-old woman complained of a resting tremor of her left hand,

difficulty writing, and a painful feeling of internal restlessness. After a thorough

neurological examination, a diagnosis was made and appropriate therapy was

prescribed, including a drug that acts as a partial agonist of dopamine D2

receptors in the brain. What drug was most likely to be prescribed?

a)

Pramipexole

b)

Selegiline

c)

Amantadine

d)

Levodopa

e)

carbamazepine

90.

30. Antiepileptie drugs should not be discontinued suddenly, but gradually, because:

a)

Tachyphylaxis may develop

b)

It is fraught with adrenal insufficiency

c)

This is a prevention of hepatotoxicity

d)

Drug addiction should be prevented

e)

The phenomenon of "recoil" may develop

91.

31. Select a benzodiazepine anticovulsant antagonist:

a)

Ditilin

b)

Buspirone

c)

Isonitrazine

d)

Naloxone

e)

Flumazenil

92.

32. Select indications for prescribing sodium valproate

a)

Depressive syndrome

b)

Manic state

c)

Grand mal seizure

d)

Meniere’s disease

e)

Parkinson’s disease

93.

33. Drugs used for drug-induced Parkinsonism

a)

Levodopa

b)

Selegiline

c)

Amantadine

d)

Biperiden

e)

Pirenzipine

94.

34. Receptor structures, blocker of which amantadine is

a)

5-HT2 receptors

b)

GABA receptors

c)

H1 receptors

d)

NMDA receptors

e)

Opioid receptors

95.

35. To treat Parkinson’s disease use:

a)

Sodium Valproate

b)

Carbamazepine

c)

Levodopa

d)

Zopiclone

e)

Diazepam

96.

36. Identify the drug : it has anti epileptic , hypnotic and sedative effects, stimulates GABAergic processes in the brain, causes the induction of microsomal liver enzymes:

a)

Phenobarbital

b)

Naloxone

c)

Fentanyl

d)

Morphine

e)

Butorphanol

97.

37. Specify the main reason why it is impossible to use dopamine as replacement therapy for Parkinsonism

a)

Dopamine causes psychosis with long term use

b)

Dopamine practically does not penetrate the blood brain barrier

c)

Dopamine practically does penetrate the blood brain barrier

d)

Dopamine is contraindicated for intravenous administration

e)

Dopamine blocks dopamine receptors

98.

38. Specify an antiparkinsonian drug, a monoamine oxidase inhibitor:

a)

Levodopa

b)

Midantan

c)

Cyclodol

d)

Selegiline

e)

Nialamide

99.

39. This drug was chosen by a doctor to treat a patient with myoclonus epilepsy.

The mechanism of action is diverse, but is not associated with the glutamatergic

system. SIDE effects : nausea, ataxia, drowsiness. Select drug

a)

Topiramate

b)

Lamotrigine

c)

Clonazepam

d)

Phenobarbital

e)

Sodium valproate

100.

40. Combined drug for the treatment for Parkinsonism. Replenishes dopamine

deficiency in the basal ganglia of the CNS. The second part of the drug prevents

the destruction of the active principle in peripheral tissues. Select drug

combination:

a)

Levodopa + Bromocriptine

b)

Levodopa + Carbidopa

c)

Amantadine + selegiline

d)

Levodopa + amantadine

e)

Amantadine + biperiden

101.

41. Antiepileptic drug, T-type calcium channel blocker:

a)

Clonazepam

b)

Ethosuximide

c)

Phenobarbital

d)

Phenytoin

e)

sodium valproate

102.

42.What drugs are used to treat Parkinson's disease?

a)

trihexyphenidyl and chlorpromazine;

b)

chlorpromazine and levodopa;

c)

levodopa and trihexyphenidyl

d)

chlorpromazine and haloperidol.

e)

carbamazepine and valproic acid

103.

43.Antiepileptic drug, the use of which may develop hyperplastic gingivitis

a)

Chlorakon

b)

Carbamazepine

c)

Sodium valproate

d)

Phenytoin

e)

Trimethin

104.

44 .What is the mechanism of action of levodopa?

a)

increases the content of gamma-aminobutyric acid (GABA) in the central nervous

system

b)

increases the content of enkephalins in the central nervous system

c)

increases the content of dopamine in the central nervous system

d)

increases the content of serotonin in the central nervous system

e)

increases the content of acetylcholine in the central nervous system

105.

45.Specify a drug that is a dopamine receptor agonist

a)

Bromocriptine

b)

levodopa

c)

tolcapone

d)

Selegiline

e)

amitriptyline

106.

46. For grand mal seizures , a drug is prescribed whose action is combined with a favourable psychotropic effect

a)

Levodopa

b)

Carbamazepine

c)

Phenobarbital

d)

Gabapentin

e)

Rispolept

107.

47. Specify a drug that is a dopamine receptor agonist

a)

Selegiline

b)

Bromocriptine

c)

levodopa

d)

amitriptyline

e)

tolcapone

108.

48.Select benzodiazepine anticonvulsant antagonist:

a)

Ditilin

b)

Buspirone

c)

Isonitrazine

d)

naloxone

e)

flumazenil

109.

49.Status epilepticus is a dangerous condition when attacks follow each other. Diazepam may be the drug of choice. Select an effect uncharacteristic of diazepam:

a)

short action

b)

isk of respiratory depression

c)

occurrence of hypotension

d)

blocks sodium channels of neurocytes

e)

causes muscle relaxation

110.

50. An 82-year-old man receiving the combination drug levodopa/carbidopa (Sinemet)

for the treatment of Parkinson's disease must be prescribed an additional drug,

because the therapeutic effect of Sinemet has become insufficient. From the

anamnesis it is known that several years ago the same patient received a certain

antiparkinsonian drug, which is also used in gynecological practice for the treatment of

infertility associated with hyperprolactinemia. What drug is this?

a)

Amantadine

b)

Bromocriptine

c)

Carbamazepine

d)

Dopamine

e)

Lorazepam

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